KEGG 05205 Proteoglycans in cancer
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa05205 Proteoglycans in cancer 85
hsa05200 Pathways in cancer 42
hsa04810 Regulation of actin cytoskeleton 35
hsa04510 Focal adhesion 34
hsa05165 Human papillomavirus infection 30
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu05205 Proteoglycans in cancer 94
mmu05200 Pathways in cancer 53
mmu04510 Focal adhesion 44
mmu05165 Human papillomavirus infection 43
mmu04810 Regulation of actin cytoskeleton 42
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno05205 Proteoglycans in cancer 108
rno05200 Pathways in cancer 61
rno05165 Human papillomavirus infection 48
rno04510 Focal adhesion 41
rno04151 PI3K-Akt signaling pathway 40
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc05205 Proteoglycans in cancer 96
mcc05200 Pathways in cancer 54
mcc04510 Focal adhesion 45
mcc04810 Regulation of actin cytoskeleton 37
mcc05163 Human cytomegalovirus infection 36
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa05205 Proteoglycans in cancer 90
cfa05200 Pathways in cancer 48
cfa04510 Focal adhesion 40
cfa05165 Human papillomavirus infection 36
cfa04151 PI3K-Akt signaling pathway 32
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca05205 Proteoglycans in cancer 88
fca05200 Pathways in cancer 49
fca04510 Focal adhesion 43
fca05165 Human papillomavirus infection 40
fca04810 Regulation of actin cytoskeleton 36
Gene list in the network
Symbol Function*
ACTB actin beta
ACTG1 actin gamma 1
AKT2 AKT serine/threonine kinase 2
ANK2 ankyrin 2
ANK3 ankyrin 3
FAS Fas cell surface death receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
RHOA ras homolog family member A
BGN biglycan
CAV1 caveolin 1
CAV2 caveolin 2
CDC42 cell division cycle 42
CFL1 cofilin 1
COL1A1 collagen type I alpha 1 chain
COL1A2 collagen type I alpha 2 chain
COL3A1 collagen type III alpha 1 chain
COL5A2 collagen type V alpha 2 chain
DCN decorin
HBEGF heparin binding EGF like growth factor
EMP3 epithelial membrane protein 3
CTTN cortactin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
GPC4 glypican 4
FGF2 fibroblast growth factor 2
FLNA filamin A
FLNB filamin B
MTOR mechanistic target of rapamycin kinase
GPC3 glypican 3
GNAI2 G protein subunit alpha i2
GPC1 glypican 1
HCLS1 hematopoietic cell-specific Lyn substrate 1
HGF hepatocyte growth factor
HSPG2 heparan sulfate proteoglycan 2
IGF1 insulin like growth factor 1
ITGA2 integrin subunit alpha 2
ITGA5 integrin subunit alpha 5
ITGAV integrin subunit alpha V
ITGB1 integrin subunit beta 1
ITGB5 integrin subunit beta 5
ITPR1 inositol 1,4,5-trisphosphate receptor type 1
ITPR2 inositol 1,4,5-trisphosphate receptor type 2
ITPR3 inositol 1,4,5-trisphosphate receptor type 3
KIF5B kinesin family member 5B
LUM lumican
MDM2 MDM2 proto-oncogene
MET MET proto-oncogene, receptor tyrosine kinase
MFGE8 milk fat globule EGF and factor V/VIII domain containing
MMP2 matrix metallopeptidase 2
MSN moesin
MYH9 myosin heavy chain 9
PPP1R12A protein phosphatase 1 regulatory subunit 12A
PCSK6 proprotein convertase subtilisin/kexin type 6
PAK1 p21 (RAC1) activated kinase 1
PCOLCE procollagen C-endopeptidase enhancer
PDGFRA platelet derived growth factor receptor alpha
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCG1 phospholipase C gamma 1
PPP1CA protein phosphatase 1 catalytic subunit alpha
PRKCD protein kinase C delta
MAPK3 mitogen-activated protein kinase 3
MAPK11 mitogen-activated protein kinase 11
MAPK13 mitogen-activated protein kinase 13
MAP2K2 mitogen-activated protein kinase kinase 2
HTRA1 HtrA serine peptidase 1
PTPN6 protein tyrosine phosphatase non-receptor type 6
PTPN11 protein tyrosine phosphatase non-receptor type 11
RAC1 Rac family small GTPase 1
ROCK1 Rho associated coiled-coil containing protein kinase 1
RPS6KA1 ribosomal protein S6 kinase A1
RPS6KB2 ribosomal protein S6 kinase B2
RRAS RAS related
MAPK12 mitogen-activated protein kinase 12
SDC1 syndecan 1
SDC2 syndecan 2
SDC4 syndecan 4
SMO smoothened, frizzled class receptor
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
SPTAN1 spectrin alpha, non-erythrocytic 1
TGFB1 transforming growth factor beta 1
THY1 Thy-1 cell surface antigen
TLN1 talin 1
TPM4 tropomyosin 4
TWIST1 twist family bHLH transcription factor 1
USF2 upstream transcription factor 2, c-fos interacting
VAV1 vav guanine nucleotide exchange factor 1
EZR ezrin
WNT3 Wnt family member 3
WNT5A Wnt family member 5A
WNT6 Wnt family member 6
WNT7B Wnt family member 7B
WNT11 Wnt family member 11
WNT9A Wnt family member 9A
FZD7 frizzled class receptor 7
FZD9 frizzled class receptor 9
CDC42BPA CDC42 binding protein kinase alpha
IQGAP1 IQ motif containing GTPase activating protein 1
SYNJ2 synaptojanin 2
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
SCAF11 SR-related CTD associated factor 11
NTN1 netrin 1
AKAP6 A-kinase anchoring protein 6
ROCK2 Rho associated coiled-coil containing protein kinase 2
KIAA0100 KIAA0100
WDR1 WD repeat domain 1
ARPC4 actin related protein 2/3 complex subunit 4
CAP1 cyclase associated actin cytoskeleton regulatory protein 1
NCKAP1 NCK associated protein 1
RRAS2 RAS related 2
NINL ninein like
ATP11B ATPase phospholipid transporting 11B (putative)
ARHGEF12 Rho guanine nucleotide exchange factor 12
TES testin LIM domain protein
TNFRSF12A TNF receptor superfamily member 12A
SEPTIN11 septin 11
WNT10A Wnt family member 10A
WNT5B Wnt family member 5B
RAB1B RAB1B, member RAS oncogene family
TMEM47 transmembrane protein 47
CREB3L1 cAMP responsive element binding protein 3 like 1
TWIST2 twist family bHLH transcription factor 2
NOTUM notum, palmitoleoyl-protein carboxylesterase
TUBB tubulin beta class I
ARHGAP30 Rho GTPase activating protein 30
SERINC2 serine incorporator 2
MIR650 microRNA 650
Symbol Function*
Actb actin, beta
Actg1 actin, gamma, cytoplasmic 1
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Rhoa ras homolog family member A
Bgn biglycan
Camk2g calcium/calmodulin-dependent protein kinase II gamma
Capns1 calpain, small subunit 1
Cav1 caveolin 1, caveolae protein
Cav2 caveolin 2
Cav3 caveolin 3
Ccnd1 cyclin D1
Cd44 CD44 antigen
Cdc42 cell division cycle 42
Cfl1 cofilin 1, non-muscle
Coro1a coronin, actin binding protein 1A
Col3a1 collagen, type III, alpha 1
Col5a1 collagen, type V, alpha 1
Col5a2 collagen, type V, alpha 2
Col1a1 collagen, type I, alpha 1
Col1a2 collagen, type I, alpha 2
Cttn cortactin
Dcn decorin
Twist2 twist basic helix-loop-helix transcription factor 2
Des desmin
Dync1h1 dynein cytoplasmic 1 heavy chain 1
Egfr epidermal growth factor receptor
Ephb3 Eph receptor B3
Ephb4 Eph receptor B4
Erbb2 erb-b2 receptor tyrosine kinase 2
Ptk2 PTK2 protein tyrosine kinase 2
Ccn2 cellular communication network factor 2
Fn1 fibronectin 1
Fzd1 frizzled class receptor 1
Fzd7 frizzled class receptor 7
Fzd8 frizzled class receptor 8
Fzd9 frizzled class receptor 9
Gas1 growth arrest specific 1
Ghr growth hormone receptor
Gpc4 glypican 4
Grb2 growth factor receptor bound protein 2
Hcls1 hematopoietic cell specific Lyn substrate 1
Ptpn6 protein tyrosine phosphatase, non-receptor type 6
Hbegf heparin-binding EGF-like growth factor
Hras Harvey rat sarcoma virus oncogene
Sdc2 syndecan 2
Hspg2 perlecan (heparan sulfate proteoglycan 2)
Inpp5d inositol polyphosphate-5-phosphatase D
Itga2 integrin alpha 2
Itga5 integrin alpha 5 (fibronectin receptor alpha)
Itgb1 integrin beta 1 (fibronectin receptor beta)
Itgb3 integrin beta 3
Itgb5 integrin beta 5
Itpr1 inositol 1,4,5-trisphosphate receptor 1
Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1
Lox lysyl oxidase
Loxl1 lysyl oxidase-like 1
Lrmp lymphoid-restricted membrane protein
Lrp1 low density lipoprotein receptor-related protein 1
Lum lumican
Mbd3 methyl-CpG binding domain protein 3
Met met proto-oncogene
Mmp14 matrix metallopeptidase 14 (membrane-inserted)
Mmp2 matrix metallopeptidase 2
Mrc2 mannose receptor, C type 2
Msn moesin
Msx2 msh homeobox 2
Myh9 myosin, heavy polypeptide 9, non-muscle
Ppp1r12a protein phosphatase 1, regulatory subunit 12A
Septin2 septin 2
Nes nestin
Nid1 nidogen 1
Nras neuroblastoma ras oncogene
Pcolce procollagen C-endopeptidase enhancer protein
Pfn1 profilin 1
Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Prkcb protein kinase C, beta
Plaur plasminogen activator, urokinase receptor
Lcp1 lymphocyte cytosolic protein 1
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Mapk11 mitogen-activated protein kinase 11
Cavin1 caveolae associated 1
Rac1 Rac family small GTPase 1
Rac2 Rac family small GTPase 2
Rock1 Rho-associated coiled-coil containing protein kinase 1
Rock2 Rho-associated coiled-coil containing protein kinase 2
Rras related RAS viral (r-ras) oncogene
Prrx2 paired related homeobox 2
Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1
Cavin2 caveolae associated 2
Sema3c sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Sparc secreted acidic cysteine rich glycoprotein
Src Rous sarcoma oncogene
Stat3 signal transducer and activator of transcription 3
Stat5a signal transducer and activator of transcription 5A
Sdc1 syndecan 1
Tgfb1 transforming growth factor, beta 1
Thbs1 thrombospondin 1
Timp3 tissue inhibitor of metalloproteinase 3
Tnf tumor necrosis factor
Twist1 twist basic helix-loop-helix transcription factor 1
Vav1 vav 1 oncogene
Ezr ezrin
Wnt10a wingless-type MMTV integration site family, member 10A
Wnt10b wingless-type MMTV integration site family, member 10B
Wnt4 wingless-type MMTV integration site family, member 4
Wnt5a wingless-type MMTV integration site family, member 5A
Wnt5b wingless-type MMTV integration site family, member 5B
Wnt6 wingless-type MMTV integration site family, member 6
Wnt7a wingless-type MMTV integration site family, member 7A
Wnt7b wingless-type MMTV integration site family, member 7B
Tlr2 toll-like receptor 2
Map2k2 mitogen-activated protein kinase kinase 2
Mapk1 mitogen-activated protein kinase 1
Mapk14 mitogen-activated protein kinase 14
Mapk3 mitogen-activated protein kinase 3
Ror2 receptor tyrosine kinase-like orphan receptor 2
Islr immunoglobulin superfamily containing leucine-rich repeat
Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a
Mapk12 mitogen-activated protein kinase 12
Iqgap1 IQ motif containing GTPase activating protein 1
Nckap1 NCK-associated protein 1
Mtch1 mitochondrial carrier 1
Mtor mechanistic target of rapamycin kinase
Fzd2 frizzled class receptor 2
Slc44a2 solute carrier family 44, member 2
Flnc filamin C, gamma
Hspb2 heat shock protein 2
Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12
Cd248 CD248 antigen, endosialin
Nipbl NIPBL cohesin loading factor
Dlg5 discs large MAGUK scaffold protein 5
Rap2b RAP2B, member of RAS oncogene family
Actr3 ARP3 actin-related protein 3
Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Ppp1r18 protein phosphatase 1, regulatory subunit 18
Gpr84 G protein-coupled receptor 84
Fzd10 frizzled class receptor 10
Csnk1g2 casein kinase 1, gamma 2
Ano6 anoctamin 6
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta
Braf Braf transforming gene
Grk2 G protein-coupled receptor kinase 2
Fgfrl1 fibroblast growth factor receptor-like 1
Hdac10 histone deacetylase 10
Flna filamin, alpha
Daam1 dishevelled associated activator of morphogenesis 1
Adamts2 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
Wnt9a wingless-type MMTV integration site family, member 9A
Taok1 TAO kinase 1
Arhgap30 Rho GTPase activating protein 30
Ppp1r12c protein phosphatase 1, regulatory subunit 12C
Plcg2 phospholipase C, gamma 2
Cpz carboxypeptidase Z
Ehd2 EH-domain containing 2
Flnb filamin, beta
Tpm4 tropomyosin 4
Frs2 fibroblast growth factor receptor substrate 2
Mast4 microtubule associated serine/threonine kinase family member 4
Ep300 E1A binding protein p300
Cdkl5 cyclin-dependent kinase-like 5
Symbol Function*
Egfr epidermal growth factor receptor
Erbb2 erb-b2 receptor tyrosine kinase 2
Igf2 insulin-like growth factor 2
Itgb1 integrin subunit beta 1
Kras KRAS proto-oncogene, GTPase
Nras NRAS proto-oncogene, GTPase
Serpine1 serpin family E member 1
Sdc4 syndecan 4
Slc9a1 solute carrier family 9 member A1
Sparc secreted protein acidic and cysteine rich
Tp53 tumor protein p53
Tpm4 tropomyosin 4
Lox lysyl oxidase
Pvr PVR cell adhesion molecule
Syk spleen associated tyrosine kinase
Vav1 vav guanine nucleotide exchange factor 1
Bgn biglycan
Sdc1 syndecan 1
Smo smoothened, frizzled class receptor
Casp3 caspase 3
Cav1 caveolin 1
Cd44 CD44 molecule (Indian blood group)
Hbegf heparin-binding EGF-like growth factor
Nrdc nardilysin convertase
Prkg2 protein kinase cGMP-dependent 2
Kdr kinase insert domain receptor
Agrn agrin
Ppp1cb protein phosphatase 1 catalytic subunit beta
Ptk2 protein tyrosine kinase 2
Sdc2 syndecan 2
Prkaca protein kinase cAMP-activated catalytic subunit alpha
Gnai3 G protein subunit alpha i3
Fn1 fibronectin 1
Itpr3 inositol 1,4,5-trisphosphate receptor, type 3
Igf1r insulin-like growth factor 1 receptor
Plcg1 phospholipase C, gamma 1
Ankrd1 ankyrin repeat domain 1
Dcn decorin
Cav3 caveolin 3
Vtn vitronectin
Tlr4 toll-like receptor 4
Itgb3 integrin subunit beta 3
Plcg2 phospholipase C, gamma 2
Col1a1 collagen type I alpha 1 chain
Shh sonic hedgehog signaling molecule
Mapk13 mitogen activated protein kinase 13
Hif1a hypoxia inducible factor 1 subunit alpha
Pcolce procollagen C-endopeptidase enhancer
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Bok BCL2 family apoptosis regulator BOK
Plaur plasminogen activator, urokinase receptor
Cr1l complement C3b/C4b receptor 1 like
Mtor mechanistic target of rapamycin kinase
Cnr2 cannabinoid receptor 2
Nckap1 NCK-associated protein 1
Fzd1 frizzled class receptor 1
Ccnd1 cyclin D1
Gpc1 glypican 1
Map2k2 mitogen activated protein kinase kinase 2
Tgfb1 transforming growth factor, beta 1
Twist2 twist family bHLH transcription factor 2
Arhgef1 Rho guanine nucleotide exchange factor 1
Mapk12 mitogen-activated protein kinase 12
Cttn cortactin
Ccn2 cellular communication network factor 2
Cdc42 cell division cycle 42
Fzd2 frizzled class receptor 2
Wnt5a Wnt family member 5A
Rab2a RAB2A, member RAS oncogene family
Fgfr1 Fibroblast growth factor receptor 1
Mtpn myotrophin
Grb2 growth factor receptor bound protein 2
Msn moesin
Lum lumican
Mmp2 matrix metallopeptidase 2
Mmp9 matrix metallopeptidase 9
Msx1 msh homeobox 1
Pdpk1 3-phosphoinositide dependent protein kinase-1
Tgfb2 transforming growth factor, beta 2
Vim vimentin
Actb actin, beta
Bmp1 bone morphogenetic protein 1
Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator
Cpz carboxypeptidase Z
Bambi BMP and activin membrane-bound inhibitor
Col3a1 collagen type III alpha 1 chain
Col1a2 collagen type I alpha 2 chain
Wnt4 Wnt family member 4
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Twist1 twist family bHLH transcription factor 1
Col5a1 collagen type V alpha 1 chain
Ptch1 patched 1
Prrx2 paired related homeobox 2
Braf B-Raf proto-oncogene, serine/threonine kinase
Wnt7a Wnt family member 7A
Cdkn1a cyclin-dependent kinase inhibitor 1A
Mapk1 mitogen activated protein kinase 1
Ptpn6 protein tyrosine phosphatase, non-receptor type 6
Rhoa ras homolog family member A
Tpm3 tropomyosin 3
Lama5 laminin subunit alpha 5
Wnt11 Wnt family member 11
Hspb2 heat shock protein family B (small) member 2
Map2k1 mitogen activated protein kinase kinase 1
Itga2 integrin subunit alpha 2
Ilk integrin-linked kinase
Foxc2 forkhead box C2
Ipmk inositol polyphosphate multikinase
Itgb5 integrin subunit beta 5
Fzd6 frizzled class receptor 6
Zfp496 zinc finger protein 496
Serpinf1 serpin family F member 1
Scarf2 scavenger receptor class F, member 2
Ephb3 Eph receptor B3
Hcls1 hematopoietic cell specific Lyn substrate 1
Evc EvC ciliary complex subunit 1
Actr2 actin related protein 2
Id4 inhibitor of DNA binding 4, HLH protein
Ppic peptidylprolyl isomerase C
Plekhg2 pleckstrin homology and RhoGEF domain containing G2
Hras HRas proto-oncogene, GTPase
Flna filamin A
Slc35g1 solute carrier family 35, member G1
Foxo3 forkhead box O3
Vav3 vav guanine nucleotide exchange factor 3
Col15a1 collagen type XV alpha 1 chain
Raver1 ribonucleoprotein, PTB-binding 1
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Eif4b eukaryotic translation initiation factor 4B
Fbxo11 F-box protein 11
Rhbdf1 rhomboid 5 homolog 1
Evpl envoplakin
Tiam1 TIAM Rac1 associated GEF 1
Orai2 ORAI calcium release-activated calcium modulator 2
Aebp1 AE binding protein 1
Flnb filamin B
Cdh5 cadherin 5
Fndc1 fibronectin type III domain containing 1
Drosha drosha ribonuclease III
Tlr2 toll-like receptor 2
Ash1l ASH1 like histone lysine methyltransferase
Mlf2 myeloid leukemia factor 2
Tln1 talin 1
Hspg2 heparan sulfate proteoglycan 2
Casz1 castor zinc finger 1
Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1
Epyc epiphycan
Frs2 fibroblast growth factor receptor substrate 2
Mdm2 MDM2 proto-oncogene
Wnt7b Wnt family member 7B
Itga5 integrin subunit alpha 5
Loxl1 lysyl oxidase-like 1
Wnt6 Wnt family member 6
Wnt10a Wnt family member 10A
Sash3 SAM and SH3 domain containing 3
Fzd5 frizzled class receptor 5
Pxn paxillin
Enah ENAH, actin regulator
Ehd2 EH-domain containing 2
Rras RAS related
Aen apoptosis enhancing nuclease
Iqgap1 IQ motif containing GTPase activating protein 1
Rps6kb2 ribosomal protein S6 kinase B2
Tspan12 tetraspanin 12
Flnc filamin C
Yap1 Yes1 associated transcriptional regulator
Cav2 caveolin 2
Rac1 Rac family small GTPase 1
Fzd10 frizzled class receptor 10
Foxc1 forkhead box C1
Fzd8 frizzled class receptor 8
Dse dermatan sulfate epimerase
Ptch2 patched 2
Arhgef12 Rho guanine nucleotide exchange factor 12
Thbs1 thrombospondin 1
Capza2 capping actin protein of muscle Z-line subunit alpha 2
Arhgap30 Rho GTPase activating protein 30
Wnt16 Wnt family member 16
Cbl Cbl proto-oncogene
Rbpj recombination signal binding protein for immunoglobulin kappa J region
Irf2bp2 interferon regulatory factor 2 binding protein 2
Ebi3 Epstein-Barr virus induced 3
Mapk11 mitogen-activated protein kinase 11
Fzd7 frizzled class receptor 7
Ap1g2 adaptor related protein complex 1 subunit gamma 2
Symbol Function*
STAT3 signal transducer and activator of transcription 3
COL3A1 collagen type III alpha 1 chain
FGF2 fibroblast growth factor 2
COL1A1 collagen type I alpha 1 chain
ACTB actin beta
TLR2 toll like receptor 2
ITGB1 integrin subunit beta 1
ITGA5 integrin subunit alpha 5
CCND1 cyclin D1
FAS Fas cell surface death receptor
TLR4 toll like receptor 4
TIMP3 TIMP metallopeptidase inhibitor 3
ERBB4 erb-b2 receptor tyrosine kinase 4
CAP1 cyclase associated actin cytoskeleton regulatory protein 1
NPEPPS aminopeptidase puromycin sensitive
ADAM17 ADAM metallopeptidase domain 17
CASP3 caspase 3
FZD6 frizzled class receptor 6
MYC MYC proto-oncogene, bHLH transcription factor
GAS1 growth arrest specific 1
COL6A3 collagen type VI alpha 3 chain
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
ADCY7 adenylate cyclase 7
CTHRC1 collagen triple helix repeat containing 1
POSTN periostin
FBLIM1 filamin binding LIM protein 1
PPP1R12A protein phosphatase 1 regulatory subunit 12A
WNT9A Wnt family member 9A
PXN paxillin
RAC2 Rac family small GTPase 2
WNT11 Wnt family member 11
FBLN5 fibulin 5
BGN biglycan
ERBB2 erb-b2 receptor tyrosine kinase 2
LMO7 LIM domain 7
AKAP13 A-kinase anchoring protein 13
ROCK1 Rho associated coiled-coil containing protein kinase 1
KDR kinase insert domain receptor
GPC1 glypican 1
IGF1 insulin like growth factor 1
MMP2 matrix metallopeptidase 2
EGF epidermal growth factor
PIK3R1 phosphoinositide-3-kinase regulatory subunit 1
ANK3 ankyrin 3
FLNA filamin A
RPS6KA5 ribosomal protein S6 kinase A5
FGFR1 fibroblast growth factor receptor 1
DPT dermatopontin
FLNC filamin C
COL4A1 collagen type IV alpha 1 chain
COL1A2 collagen type I alpha 2 chain
EIF3H eukaryotic translation initiation factor 3 subunit H
TMEM43 transmembrane protein 43
SRC SRC proto-oncogene, non-receptor tyrosine kinase
PRKCB protein kinase C beta
SMO smoothened, frizzled class receptor
PSD4 pleckstrin and Sec7 domain containing 4
GRB2 growth factor receptor bound protein 2
CAMK2D calcium/calmodulin dependent protein kinase II delta
PRELP proline and arginine rich end leucine rich repeat protein
FLNB filamin B
FZD7 frizzled class receptor 7
LCP1 lymphocyte cytosolic protein 1
GNAI2 G protein subunit alpha i2
FZD1 frizzled class receptor 1
LAPTM5 lysosomal protein transmembrane 5
CAV1 caveolin 1
MET MET proto-oncogene, receptor tyrosine kinase
HIF1A hypoxia inducible factor 1 subunit alpha
WNT2 Wnt family member 2
FHIP2A FHF complex subunit HOOK interacting protein 2A
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
LOC705671 actin, cytoplasmic 2-like
NCKAP1L NCK associated protein 1 like
PLAU plasminogen activator, urokinase
ZYX zyxin
RHOA ras homolog family member A
PDLIM7 PDZ and LIM domain 7
GPC3 glypican 3
TES testin LIM domain protein
CAV2 caveolin 2
TNFRSF19 TNF receptor superfamily member 19
HSPG2 heparan sulfate proteoglycan 2
HIP1R huntingtin interacting protein 1 related
TFAP4 transcription factor AP-4
TGFB2 transforming growth factor beta 2
TCF21 transcription factor 21
WNT4 Wnt family member 4
MMP9 matrix metallopeptidase 9
CLMP CXADR like membrane protein
THBS2 thrombospondin 2
CTTN cortactin
FZD8 frizzled class receptor 8
ROCK2 Rho associated coiled-coil containing protein kinase 2
ITPR2 inositol 1,4,5-trisphosphate receptor type 2
CCNYL1 cyclin Y like 1
RDX radixin
NRAS NRAS proto-oncogene, GTPase
IQGAP1 IQ motif containing GTPase activating protein 1
PCBP1 poly(rC) binding protein 1
PRKACB protein kinase cAMP-activated catalytic subunit beta
LUM lumican
DCN decorin
PPP1CC protein phosphatase 1 catalytic subunit gamma
EEA1 early endosome antigen 1
MAP2K1 mitogen-activated protein kinase kinase 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
PFN1 profilin 1
FZD5 frizzled class receptor 5
IGF2 insulin like growth factor 2
SDC4 syndecan 4
MSN moesin
RRS1 ribosome biogenesis regulator 1 homolog
PTPN11 protein tyrosine phosphatase non-receptor type 11
ARHGEF12 Rho guanine nucleotide exchange factor 12
GP1BB glycoprotein Ib platelet subunit beta
CD9 CD9 molecule
LOC712274 40S ribosomal protein S6
CLIC4 chloride intracellular channel 4
SPARC secreted protein acidic and cysteine rich
PCOLCE procollagen C-endopeptidase enhancer
VAV2 vav guanine nucleotide exchange factor 2
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif 2
FBLN1 fibulin 1
ACTG1 actin gamma 1
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
CD34 CD34 molecule
WNT7B Wnt family member 7B
CCR9 C-C motif chemokine receptor 9
HCLS1 hematopoietic cell-specific Lyn substrate 1
PTPN6 protein tyrosine phosphatase non-receptor type 6
NYNRIN NYN domain and retroviral integrase containing
ITGB5 integrin subunit beta 5
MAPK12 mitogen-activated protein kinase 12
MAPK11 mitogen-activated protein kinase 11
CEP350 centrosomal protein 350
CD44 CD44 molecule
ITGB3 integrin subunit beta 3
KIAA2026 KIAA2026
TAP1 transporter 1, ATP binding cassette subfamily B member
RAC1 Rac family small GTPase 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
COL12A1 collagen type XII alpha 1 chain
INPP5D inositol polyphosphate-5-phosphatase D
IRAK3 interleukin 1 receptor associated kinase 3
ITPR3 inositol 1,4,5-trisphosphate receptor type 3
CHMP6 charged multivesicular body protein 6
PRKCA protein kinase C alpha
MAPK13 mitogen-activated protein kinase 13
WNT5B Wnt family member 5B
RPS6KB2 ribosomal protein S6 kinase B2
PPP1CA protein phosphatase 1 catalytic subunit alpha
MAP2K2 mitogen-activated protein kinase kinase 2
CFL1 cofilin 1
FERMT3 FERM domain containing kindlin 3
VAV1 vav guanine nucleotide exchange factor 1
TSTD1 thiosulfate sulfurtransferase like domain containing 1
OLFML1 olfactomedin like 1
CPZ carboxypeptidase Z
MYL6B myosin light chain 6B
TGFB1 transforming growth factor beta 1
TMEM158 transmembrane protein 158
Symbol Function*
TLR4 toll like receptor 4
PLAU plasminogen activator, urokinase
MET MET proto-oncogene, receptor tyrosine kinase
HSPG2 heparan sulfate proteoglycan 2
PRKACA protein kinase cAMP-activated catalytic subunit alpha
ACTB actin beta
COL1A1 collagen type I alpha 1 chain
MDM2 MDM2 proto-oncogene
MMP2 matrix metallopeptidase 2
ITGB3 integrin subunit beta 3
COL1A2 collagen type I alpha 2 chain
FN1 fibronectin 1
FGF2 fibroblast growth factor 2
ERBB2 erb-b2 receptor tyrosine kinase 2
MMP9 matrix metallopeptidase 9
DCN decorin
CD44 CD44 molecule
CAV1 caveolin 1
RAB5A RAB5A, member RAS oncogene family
EGFR epidermal growth factor receptor
PTGS2 prostaglandin-endoperoxide synthase 2
IGF1R insulin like growth factor 1 receptor
TLR2 toll like receptor 2
AKT2 AKT serine/threonine kinase 2
CCND1 cyclin D1
FRS2 fibroblast growth factor receptor substrate 2
CNOT2 CCR4-NOT transcription complex subunit 2
DMXL1 Dmx like 1
CDKN1A cyclin dependent kinase inhibitor 1A
CALU calumenin
CAV2 caveolin 2
CAP1 cyclase associated actin cytoskeleton regulatory protein 1
PPP1R12A protein phosphatase 1 regulatory subunit 12A
ACTG1 actin gamma 1
CCN2 cellular communication network factor 2
SYMPK symplekin
PLAUR plasminogen activator, urokinase receptor
ITPR1 inositol 1,4,5-trisphosphate receptor type 1
DDA1 DET1 and DDB1 associated 1
ACP5 acid phosphatase 5, tartrate resistant
CTNNB1 catenin beta 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
ATP9A ATPase phospholipid transporting 9A (putative)
POSTN periostin
PTPN11 protein tyrosine phosphatase non-receptor type 11
MFAP5 microfibril associated protein 5
NRP1 neuropilin 1
ITGB1 integrin subunit beta 1
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
SLC9A1 solute carrier family 9 member A1
ALCAM activated leukocyte cell adhesion molecule
CCDC80 coiled-coil domain containing 80
COL3A1 collagen type III alpha 1 chain
COL5A2 collagen type V alpha 2 chain
IQGAP1 IQ motif containing GTPase activating protein 1
ANK3 ankyrin 3
VCL vinculin
ARHGEF12 Rho guanine nucleotide exchange factor 12
RDX radixin
PDPK1 3-phosphoinositide dependent protein kinase 1
ARHGAP29 Rho GTPase activating protein 29
ROCK1 Rho associated coiled-coil containing protein kinase 1
RPS6KB1 ribosomal protein S6 kinase B1
COL5A1 collagen type V alpha 1 chain
ATRX ATRX chromatin remodeler
FLNA filamin A
ERBB3 erb-b2 receptor tyrosine kinase 3
MYH9 myosin heavy chain 9
TIMP3 TIMP metallopeptidase inhibitor 3
ARHGAP25 Rho GTPase activating protein 25
WNT9A Wnt family member 9A
SMO smoothened, frizzled class receptor
FLNC filamin C
FZD1 frizzled class receptor 1
MKNK1 MAPK interacting serine/threonine kinase 1
KERA keratocan
LUM lumican
ZYX zyxin
PLAT plasminogen activator, tissue type
ROCK2 Rho associated coiled-coil containing protein kinase 2
SLC20A1 solute carrier family 20 member 1
WNT2B Wnt family member 2B
GRB2 growth factor receptor bound protein 2
CTNND1 catenin delta 1
EZR ezrin
PTCH1 patched 1
SYK spleen associated tyrosine kinase
CD37 CD37 molecule
FLNB filamin B
FKBP8 FKBP prolyl isomerase 8
VAV1 vav guanine nucleotide exchange factor 1
FZD4 frizzled class receptor 4
SDC4 syndecan 4
GPC1 glypican 1
PXN paxillin
ITGA5 integrin subunit alpha 5
ITPR2 inositol 1,4,5-trisphosphate receptor type 2
PTPN6 protein tyrosine phosphatase non-receptor type 6
PLCE1 phospholipase C epsilon 1
THBS1 thrombospondin 1
NEO1 neogenin 1
ITGAV integrin subunit alpha V
FZD7 frizzled class receptor 7
ERBB4 erb-b2 receptor tyrosine kinase 4
WNT6 Wnt family member 6
TGFB2 transforming growth factor beta 2
ITGA2 integrin subunit alpha 2
OSMR oncostatin M receptor
CBL Cbl proto-oncogene
GPR153 G protein-coupled receptor 153
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
PLCG2 phospholipase C gamma 2
FZD9 frizzled class receptor 9
CORO1A coronin 1A
PRKCB protein kinase C beta
UBN1 ubinuclein 1
MAPKAPK2 MAPK activated protein kinase 2
NYNRIN NYN domain and retroviral integrase containing
AKT1 AKT serine/threonine kinase 1
STAT3 signal transducer and activator of transcription 3
MSN moesin
FHL1 four and a half LIM domains 1
HBEGF heparin binding EGF like growth factor
MEDAG mesenteric estrogen dependent adipogenesis
VAV2 vav guanine nucleotide exchange factor 2
FAP fibroblast activation protein alpha
FSTL1 follistatin like 1
RAB31 RAB31, member RAS oncogene family
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
CTTN cortactin
NOTCH3 notch receptor 3
CAMK2D calcium/calmodulin dependent protein kinase II delta
SERPINF1 serpin family F member 1
MAP2K2 mitogen-activated protein kinase kinase 2
WNT2 Wnt family member 2
WNT4 Wnt family member 4
TMEM98 transmembrane protein 98
PPP1R12C protein phosphatase 1 regulatory subunit 12C
DIAPH1 diaphanous related formin 1
SSPN sarcospan
EP300 E1A binding protein p300
HCLS1 hematopoietic cell-specific Lyn substrate 1
LRRC17 leucine rich repeat containing 17
PODN podocan
MYH14 myosin heavy chain 14
ZMAT3 zinc finger matrin-type 3
EPYC epiphycan
SPARC secreted protein acidic and cysteine rich
CD53 CD53 molecule
ARHGEF1 Rho guanine nucleotide exchange factor 1
TLN1 talin 1
FGFRL1 fibroblast growth factor receptor like 1
LOC102155568 uncharacterized LOC102155568
LOC111097892 uncharacterized LOC111097892
LOC119870648 pantetheinase-like
Symbol Function*
CAV2 caveolin 2
CAV1 caveolin 1
MET MET proto-oncogene, receptor tyrosine kinase
TLR4 toll like receptor 4
HGF hepatocyte growth factor
TLR2 toll like receptor 2
CASP3 caspase 3
CDKN1A cyclin dependent kinase inhibitor 1A
ITGB1 integrin subunit beta 1
CCND1 cyclin D1
THBD thrombomodulin
FGF2 fibroblast growth factor 2
ACTG1 actin gamma 1
DAG1 dystroglycan 1
AKT2 AKT serine/threonine kinase 2
EGFR epidermal growth factor receptor
CTHRC1 collagen triple helix repeat containing 1
MXRA5 matrix remodeling associated 5
NEK6 NIMA related kinase 6
MSN moesin
PXN paxillin
FLNC filamin C
COL6A3 collagen type VI alpha 3 chain
MAP2K1 mitogen-activated protein kinase kinase 1
FN1 fibronectin 1
SOCS3 suppressor of cytokine signaling 3
COL5A1 collagen type V alpha 1 chain
FLNA filamin A
PHF3 PHD finger protein 3
FZD1 frizzled class receptor 1
PDGFRL platelet derived growth factor receptor like
USP4 ubiquitin specific peptidase 4
CRIM1 cysteine rich transmembrane BMP regulator 1
WNT7A Wnt family member 7A
CD248 CD248 molecule
ARHGEF1 Rho guanine nucleotide exchange factor 1
CAMK2A calcium/calmodulin dependent protein kinase II alpha
PTCH1 patched 1
FZD2 frizzled class receptor 2
PTPN11 protein tyrosine phosphatase non-receptor type 11
ARHGEF12 Rho guanine nucleotide exchange factor 12
LOC101085837 myosin regulatory light polypeptide 9
CLEC1A C-type lectin domain family 1 member A
KCTD10 potassium channel tetramerization domain containing 10
ERC1 ELKS/RAB6-interacting/CAST family member 1
FZD7 frizzled class receptor 7
VAV3 vav guanine nucleotide exchange factor 3
MID2 midline 2
PRND prion like protein doppel
MAPK1 mitogen-activated protein kinase 1
IQGAP1 IQ motif containing GTPase activating protein 1
SEPHS1 selenophosphate synthetase 1
CD276 CD276 molecule
AKT1 AKT serine/threonine kinase 1
EHD2 EH domain containing 2
GAB1 GRB2 associated binding protein 1
EP300 E1A binding protein p300
PLCE1 phospholipase C epsilon 1
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
PRKCB protein kinase C beta
FBLN1 fibulin 1
COL1A2 collagen type I alpha 2 chain
RASGEF1B RasGEF domain family member 1B
ARAF A-Raf proto-oncogene, serine/threonine kinase
NUDT6 nudix hydrolase 6
ITGA2 integrin subunit alpha 2
WNT16 Wnt family member 16
PRKACA protein kinase cAMP-activated catalytic subunit alpha
PLXNA1 plexin A1
RDX radixin
FRMD4B FERM domain containing 4B
FKBP9 FKBP prolyl isomerase 9
TIMP3 TIMP metallopeptidase inhibitor 3
PLAUR plasminogen activator, urokinase receptor
PCOLCE procollagen C-endopeptidase enhancer
COL1A1 collagen type I alpha 1 chain
TPM4 tropomyosin 4
LIMD1 LIM domain containing 1
ROCK1 Rho associated coiled-coil containing protein kinase 1
THBS1 thrombospondin 1
MRAS muscle RAS oncogene homolog
TLN1 talin 1
NUDT16L1 nudix hydrolase 16 like 1
PIK3R3 phosphoinositide-3-kinase regulatory subunit 3
IGF2 insulin like growth factor 2
MYH9 myosin heavy chain 9
ITGA5 integrin subunit alpha 5
WNT10B Wnt family member 10B
ACTN4 actinin alpha 4
TWIST1 twist family bHLH transcription factor 1
WNT1 Wnt family member 1
LIMS1 LIM zinc finger domain containing 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
ROCK2 Rho associated coiled-coil containing protein kinase 2
HSPG2 heparan sulfate proteoglycan 2
RRAS2 RAS related 2
CDC42 cell division cycle 42
FLRT3 fibronectin leucine rich transmembrane protein 3
WNT4 Wnt family member 4
DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2
PRKACB protein kinase cAMP-activated catalytic subunit beta
TFAP4 transcription factor AP-4
PRRX2 paired related homeobox 2
RRAS RAS related
ANK1 ankyrin 1
LOC101096508 E3 ubiquitin-protein ligase CBL
PVR PVR cell adhesion molecule
CTNNB1 catenin beta 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
FZD5 frizzled class receptor 5
MTOR mechanistic target of rapamycin kinase
MTMR1 myotubularin related protein 1
PLAU plasminogen activator, urokinase
ACTB actin beta
FLNB filamin B
CAMK2B calcium/calmodulin dependent protein kinase II beta
CPXM1 carboxypeptidase X, M14 family member 1
CPZ carboxypeptidase Z
MMP2 matrix metallopeptidase 2
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
PLXNB2 plexin B2
COL3A1 collagen type III alpha 1 chain
FLII FLII actin remodeling protein
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
ZYX zyxin
COL5A2 collagen type V alpha 2 chain
IHH Indian hedgehog signaling molecule
PACC1 proton activated chloride channel 1
MAP2K2 mitogen-activated protein kinase kinase 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
RNF175 ring finger protein 175
TMEM47 transmembrane protein 47
KERA keratocan
LUM lumican
DCN decorin
ITGB5 integrin subunit beta 5
RAC1 Rac family small GTPase 1
ARL5A ADP ribosylation factor like GTPase 5A
LOC102901005 uncharacterized LOC102901005
LOC102902292 uncharacterized LOC102902292
LOC105261147 collagen alpha-1(I) chain
TWIST2 twist family bHLH transcription factor 2
MAPK12 mitogen-activated protein kinase 12
LOC111557124 uncharacterized LOC111557124
SHH sonic hedgehog signaling molecule
PITPNM3 PITPNM family member 3


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