functional annotation |
Function |
epoxide hydrolase 1, microsomal |
|
GO BP |
GO:0097176 [list] [network] epoxide metabolic process
|
(4 genes)
|
IBA
ISO
|
|
GO:0034312 [list] [network] diol biosynthetic process
|
(20 genes)
|
ISO
|
|
GO:0019369 [list] [network] arachidonic acid metabolic process
|
(78 genes)
|
IBA
ISO
|
|
GO:0009636 [list] [network] response to toxic substance
|
(123 genes)
|
IEA
|
|
GO:0019439 [list] [network] aromatic compound catabolic process
|
(305 genes)
|
IEA
|
|
GO:0014070 [list] [network] response to organic cyclic compound
|
(731 genes)
|
IMP
|
|
GO:0006725 [list] [network] cellular aromatic compound metabolic process
|
(2451 genes)
|
IMP
|
|
|
GO CC |
GO:0005783 [list] [network] endoplasmic reticulum
|
(1825 genes)
|
IEA
|
|
GO:0005886 [list] [network] plasma membrane
|
(5442 genes)
|
ISO
|
|
GO:0016021 [list] [network] integral component of membrane
|
(5954 genes)
|
IEA
|
|
GO:0016020 [list] [network] membrane
|
(9571 genes)
|
ISO
|
|
GO:0043231 [list] [network] intracellular membrane-bounded organelle
|
(11551 genes)
|
ISO
|
|
|
GO MF |
GO:0033961 [list] [network] cis-stilbene-oxide hydrolase activity
|
(1 genes)
|
ISO
|
|
GO:0004301 [list] [network] epoxide hydrolase activity
|
(5 genes)
|
IBA
ISO
|
|
GO:0019899 [list] [network] enzyme binding
|
(2298 genes)
|
ISO
|
|
GO:0016787 [list] [network] hydrolase activity
|
(2400 genes)
|
IEA
|
|
GO:0003824 [list] [network] catalytic activity
|
(5635 genes)
|
IEA
|
|
|
KEGG |
mmu00980 [list] [network] Metabolism of xenobiotics by cytochrome P450 (73 genes) |
|
mmu04976 [list] [network] Bile secretion (100 genes) |
|
mmu05204 [list] [network] Chemical carcinogenesis - DNA adducts (84 genes) |
|
mmu05207 [list] [network] Chemical carcinogenesis - receptor activation (225 genes) |
|
mmu05208 [list] [network] Chemical carcinogenesis - reactive oxygen species (222 genes) |
|
Protein |
NP_001299847.1
NP_034275.1
|
BLAST |
NP_001299847.1
NP_034275.1
|
Orthologous |
[Ortholog page]
EPHX1 (hsa)
Ephx1 (rno)
Jheh2 (dme)
Jheh3 (dme)
W01A11.1 (cel)
Jheh1 (dme)
ephx5 (dre)
ephx1 (dre)
EPHX1 (gga)
EPHX1L (gga)
EPHX1 (cfa)
EPHX1 (mcc)
C45B11.6 (cel)
EPHX1 (fca)
|
Subcellular localization wolf |
E.R. 4,
pero 3,
extr 2
|
(predict for NP_001299847.1)
|
E.R. 3,
pero 3,
extr 2
|
(predict for NP_034275.1)
|
|
Gene coexpression |
Network*for coexpressed genes |
KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
mmu00982 |
Drug metabolism - cytochrome P450 |
13 |
|
mmu00980 |
Metabolism of xenobiotics by cytochrome P450 |
12 |
|
mmu05204 |
Chemical carcinogenesis - DNA adducts |
12 |
|
mmu00983 |
Drug metabolism - other enzymes |
11 |
|
mmu05207 |
Chemical carcinogenesis - receptor activation |
11 |
|
Genes directly connected with Ephx1 on the network
coex z* |
Locus |
Function* |
Coexpression detail |
CoexPub |
Entrez Gene ID* |
7.4 |
Gstm1 |
glutathione S-transferase, mu 1 |
[detail] |
9 |
14862 |
6.9 |
Aox1 |
aldehyde oxidase 1 |
[detail] |
3 |
11761 |
6.2 |
Dglucy |
D-glutamate cyclase |
[detail] |
0 |
217830 |
6.0 |
Cd81 |
CD81 antigen |
[detail] |
0 |
12520 |
|
Coexpressed gene list |
[Coexpressed gene list for Ephx1]
|
Gene expression |
All samples |
[Expression pattern for all samples]
|
Tissue specificity* |
|