KEGG 05207 Chemical carcinogenesis - receptor activation
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa05207 Chemical carcinogenesis - receptor activation 77
hsa05200 Pathways in cancer 40
hsa00980 Metabolism of xenobiotics by cytochrome P450 26
hsa05204 Chemical carcinogenesis - DNA adducts 25
hsa05208 Chemical carcinogenesis - reactive oxygen species 23
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu05207 Chemical carcinogenesis - receptor activation 102
mmu05200 Pathways in cancer 52
mmu05204 Chemical carcinogenesis - DNA adducts 42
mmu05208 Chemical carcinogenesis - reactive oxygen species 36
mmu00980 Metabolism of xenobiotics by cytochrome P450 36
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno05207 Chemical carcinogenesis - receptor activation 101
rno05200 Pathways in cancer 56
rno05204 Chemical carcinogenesis - DNA adducts 40
rno00980 Metabolism of xenobiotics by cytochrome P450 34
rno05208 Chemical carcinogenesis - reactive oxygen species 34
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc05207 Chemical carcinogenesis - receptor activation 74
mcc05200 Pathways in cancer 43
mcc05208 Chemical carcinogenesis - reactive oxygen species 29
mcc05163 Human cytomegalovirus infection 26
mcc04926 Relaxin signaling pathway 25
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa05207 Chemical carcinogenesis - receptor activation 61
cfa05200 Pathways in cancer 43
cfa05208 Chemical carcinogenesis - reactive oxygen species 27
cfa05225 Hepatocellular carcinoma 25
cfa04935 Growth hormone synthesis, secretion and action 24
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca05207 Chemical carcinogenesis - receptor activation 51
fca05200 Pathways in cancer 34
fca05208 Chemical carcinogenesis - reactive oxygen species 23
fca05225 Hepatocellular carcinoma 19
fca04935 Growth hormone synthesis, secretion and action 19
Gene list in the network
Symbol Function*
ADCY1 adenylate cyclase 1
ADCY8 adenylate cyclase 8
ADCY9 adenylate cyclase 9
AFM afamin
AHR aryl hydrocarbon receptor
AKT2 AKT serine/threonine kinase 2
APOC3 apolipoprotein C3
ARRB2 arrestin beta 2
ATF3 activating transcription factor 3
FMNL1 formin like 1
CACNA1A calcium voltage-gated channel subunit alpha1 A
CACNA1B calcium voltage-gated channel subunit alpha1 B
CCND3 cyclin D3
CCNE1 cyclin E1
CDC6 cell division cycle 6
CDC25A cell division cycle 25A
CHRNA4 cholinergic receptor nicotinic alpha 4 subunit
CREB1 cAMP responsive element binding protein 1
ATF2 activating transcription factor 2
ATF6B activating transcription factor 6 beta
CYP1A1 cytochrome P450 family 1 subfamily A member 1
CYP1A2 cytochrome P450 family 1 subfamily A member 2
CYP1B1 cytochrome P450 family 1 subfamily B member 1
CYP2B6 cytochrome P450 family 2 subfamily B member 6
CYP3A4 cytochrome P450 family 3 subfamily A member 4
CYP3A5 cytochrome P450 family 3 subfamily A member 5
DUSP1 dual specificity phosphatase 1
EPHX1 epoxide hydrolase 1
F9 coagulation factor IX
FGF7 fibroblast growth factor 7
FGF10 fibroblast growth factor 10
FOS Fos proto-oncogene, AP-1 transcription factor subunit
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
MTOR mechanistic target of rapamycin kinase
GNAI3 G protein subunit alpha i3
GNAS GNAS complex locus
GRB2 growth factor receptor bound protein 2
ARHGAP35 Rho GTPase activating protein 35
GSTA1 glutathione S-transferase alpha 1
GSTA2 glutathione S-transferase alpha 2
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2
GSTM3 glutathione S-transferase mu 3
GSTM4 glutathione S-transferase mu 4
GSTM5 glutathione S-transferase mu 5
HSPA8 heat shock protein family A (Hsp70) member 8
HSP90AA1 heat shock protein 90 alpha family class A member 1
HSP90AB1 heat shock protein 90 alpha family class B member 1
JUN Jun proto-oncogene, AP-1 transcription factor subunit
KPNA1 karyopherin subunit alpha 1
KPNA3 karyopherin subunit alpha 3
KPNA4 karyopherin subunit alpha 4
MGST1 microsomal glutathione S-transferase 1
NFKB1 nuclear factor kappa B subunit 1
NOTCH1 notch receptor 1
NRAS NRAS proto-oncogene, GTPase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
PRKCA protein kinase C alpha
MAP2K2 mitogen-activated protein kinase kinase 2
RB1 RB transcriptional corepressor 1
RELB RELB proto-oncogene, NF-kB subunit
RPS6KA1 ribosomal protein S6 kinase A1
RXRA retinoid X receptor alpha
RXRB retinoid X receptor beta
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
STAT3 signal transducer and activator of transcription 3
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
UGT2B4 UDP glucuronosyltransferase family 2 member B4
UGT2B7 UDP glucuronosyltransferase family 2 member B7
UGT2B10 UDP glucuronosyltransferase family 2 member B10
UGT2B15 UDP glucuronosyltransferase family 2 member B15
UGT2B17 UDP glucuronosyltransferase family 2 member B17
USF2 upstream transcription factor 2, c-fos interacting
TFEB transcription factor EB
FGF17 fibroblast growth factor 17
EXO1 exonuclease 1
KLF4 Kruppel like factor 4
IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon
PTGES3 prostaglandin E synthase 3
UGT2A1 UDP glucuronosyltransferase family 2 member A1 complex locus
ZHX3 zinc fingers and homeoboxes 3
ATP11B ATPase phospholipid transporting 11B (putative)
UBR4 ubiquitin protein ligase E3 component n-recognin 4
SF3B1 splicing factor 3b subunit 1
KPNA6 karyopherin subunit alpha 6
AIPL1 aryl hydrocarbon receptor interacting protein like 1
CACYBP calcyclin binding protein
DLL1 delta like canonical Notch ligand 1
UGT1A10 UDP glucuronosyltransferase family 1 member A10
UGT1A9 UDP glucuronosyltransferase family 1 member A9
UGT1A4 UDP glucuronosyltransferase family 1 member A4
UGT1A1 UDP glucuronosyltransferase family 1 member A1
MCM10 minichromosome maintenance 10 replication initiation factor
COL20A1 collagen type XX alpha 1 chain
SMAP2 small ArfGAP2
UGT2A3 UDP glucuronosyltransferase family 2 member A3
CREB3L3 cAMP responsive element binding protein 3 like 3
ATCAY ATCAY kinesin light chain interacting caytaxin
PAQR8 progestin and adipoQ receptor family member 8
CSMD2 CUB and Sushi multiple domains 2
OSBPL11 oxysterol binding protein like 11
RIMS4 regulating synaptic membrane exocytosis 4
PAQR7 progestin and adipoQ receptor family member 7
LOC100130691 uncharacterized LOC100130691
LOC101927136 uncharacterized LOC101927136
Symbol Function*
Adcy7 adenylate cyclase 7
Adcy8 adenylate cyclase 8
Adcy9 adenylate cyclase 9
Adrb2 adrenergic receptor, beta 2
Adrb3 adrenergic receptor, beta 3
Ahr aryl-hydrocarbon receptor
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Aox1 aldehyde oxidase 1
Ar androgen receptor
Atf2 activating transcription factor 2
Atf3 activating transcription factor 3
Atf4 activating transcription factor 4
Btg2 BTG anti-proliferation factor 2
Nr1i3 nuclear receptor subfamily 1, group I, member 3
Coro1a coronin, actin binding protein 1A
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2
Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1
Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4
Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10
Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13
Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9
Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38
Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11
Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13
Cyp3a16 cytochrome P450, family 3, subfamily a, polypeptide 16
Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1
Ddt D-dopachrome tautomerase
Dll1 delta like canonical Notch ligand 1
Dll3 delta like canonical Notch ligand 3
E2f1 E2F transcription factor 1
Egfr epidermal growth factor receptor
Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1
Ephx1 epoxide hydrolase 1, microsomal
Ephx2 epoxide hydrolase 2, cytoplasmic
Esr1 estrogen receptor 1 (alpha)
Fgf10 fibroblast growth factor 10
Fos FBJ osteosarcoma oncogene
Fosb FBJ osteosarcoma oncogene B
Gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting 1
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2
Gnb2 guanine nucleotide binding protein (G protein), beta 2
Gsta2 glutathione S-transferase, alpha 2 (Yc2)
Gsta3 glutathione S-transferase, alpha 3
Gsta4 glutathione S-transferase, alpha 4
Gstm1 glutathione S-transferase, mu 1
Gstm2 glutathione S-transferase, mu 2
Gstm3 glutathione S-transferase, mu 3
Gstm4 glutathione S-transferase, mu 4
Gstm6 glutathione S-transferase, mu 6
Gstt1 glutathione S-transferase, theta 1
Gstt2 glutathione S-transferase, theta 2
Gsto1 glutathione S-transferase omega 1
Hras Harvey rat sarcoma virus oncogene
Hspa8 heat shock protein 8
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1
Kpnb1 karyopherin (importin) beta 1
Jun jun proto-oncogene
Klf2 Kruppel-like factor 2 (lung)
Klf4 Kruppel-like factor 4 (gut)
Kpna1 karyopherin (importin) alpha 1
Kpna3 karyopherin (importin) alpha 3
Kpna4 karyopherin (importin) alpha 4
Kpna6 karyopherin (importin) alpha 6
Kras Kirsten rat sarcoma viral oncogene homolog
Ksr1 kinase suppressor of ras 1
Mbd3 methyl-CpG binding domain protein 3
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
Nras neuroblastoma ras oncogene
Otc ornithine transcarbamylase
Pappa pregnancy-associated plasma protein A
Pgr progesterone receptor
Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Prkca protein kinase C, alpha
Prkcb protein kinase C, beta
Phox2b paired-like homeobox 2b
Prkx protein kinase, X-linked
Dusp1 dual specificity phosphatase 1
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Stat3 signal transducer and activator of transcription 3
Stat5a signal transducer and activator of transcription 5A
Stat5b signal transducer and activator of transcription 5B
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
Th tyrosine hydroxylase
Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5
Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor
Trpv2 transient receptor potential cation channel, subfamily V, member 2
Arih1 ariadne RBR E3 ubiquitin protein ligase 1
Cdc6 cell division cycle 6
Map2k2 mitogen-activated protein kinase kinase 2
Mapk3 mitogen-activated protein kinase 3
Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6
Slco1a1 solute carrier organic anion transporter family, member 1a1
Sult1d1 sulfotransferase family 1D, member 1
Rdh7 retinol dehydrogenase 7
Dll4 delta like canonical Notch ligand 4
Set SET nuclear oncogene
Nupr1 nuclear protein transcription regulator 1
Ptges3 prostaglandin E synthase 3
Rybp RING1 and YY1 binding protein
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25
Mtch1 mitochondrial carrier 1
Mgst1 microsomal glutathione S-transferase 1
Mtor mechanistic target of rapamycin kinase
Nudt11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
Sqor sulfide quinone oxidoreductase
Rps6ka6 ribosomal protein S6 kinase polypeptide 6
Ptgr1 prostaglandin reductase 1
Gstm7 glutathione S-transferase, mu 7
Chac1 ChaC, cation transport regulator 1
St13 suppression of tumorigenicity 13
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1
Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3
Paqr8 progestin and adipoQ receptor family member VIII
Cyp2d26 cytochrome P450, family 2, subfamily d, polypeptide 26
Dtl denticleless E3 ubiquitin protein ligase
Ugt2a1 UDP glucuronosyltransferase 2 family, polypeptide A1
Ugt1a6a UDP glucuronosyltransferase 1 family, polypeptide A6A
Ugt2b38 UDP glucuronosyltransferase 2 family, polypeptide B38
Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34
Ces2a carboxylesterase 2A
Gstt3 glutathione S-transferase, theta 3
Csnk1g2 casein kinase 1, gamma 2
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4
Rps6ka3 ribosomal protein S6 kinase polypeptide 3
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3
Chrna2 cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
Ugt2b37 UDP glucuronosyltransferase 2 family, polypeptide B37
Mlc1 megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
Mgst2 microsomal glutathione S-transferase 2
Arrb2 arrestin, beta 2
Cdc27 cell division cycle 27
Cps1 carbamoyl-phosphate synthetase 1
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36
Acsm2 acyl-CoA synthetase medium-chain family member 2
Kcns3 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
Ugt2b35 UDP glucuronosyltransferase 2 family, polypeptide B35
Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13
Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44
Xkr9 X-linked Kx blood group related 9
Ces3a carboxylesterase 3A
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C
Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5
Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9
Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B
Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1
Cyp2c67 cytochrome P450, family 2, subfamily c, polypeptide 67
9130409I23Rik RIKEN cDNA 9130409I23 gene
Sult2a2 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
Symbol Function*
Ar androgen receptor
Cacna1c calcium voltage-gated channel subunit alpha1 C
Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2
Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1
Gsta1 glutathione S-transferase alpha 1
Gsta2 glutathione S-transferase alpha 2
Gstm1 glutathione S-transferase mu 1
Gstm2 glutathione S-transferase mu 2
Jak2 Janus kinase 2
Jun Jun proto-oncogene, AP-1 transcription factor subunit
Nras NRAS proto-oncogene, GTPase
Rb1 RB transcriptional corepressor 1
Ugt1a1 UDP glucuronosyltransferase family 1 member A1
Ugt2b UDP glycosyltransferase 2 family, polypeptide B
Esr1 estrogen receptor 1
Sult2a6 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
Stat5a signal transducer and activator of transcription 5A
Chrna3 cholinergic receptor nicotinic alpha 3 subunit
Chrnb4 cholinergic receptor nicotinic beta 4 subunit
Stat5b signal transducer and activator of transcription 5B
Ccnd3 cyclin D3
Akt2 AKT serine/threonine kinase 2
Gstt1 glutathione S-transferase theta 1
Rxra retinoid X receptor alpha
Ephx1 epoxide hydrolase 1
Oxtr oxytocin receptor
Arrb1 arrestin, beta 1
Atf3 activating transcription factor 3
Fgf10 fibroblast growth factor 10
Prph2 peripherin 2
Chrna4 cholinergic receptor nicotinic alpha 4 subunit
Prkaca protein kinase cAMP-activated catalytic subunit alpha
Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
Gnai3 G protein subunit alpha i3
Adrb3 adrenoceptor beta 3
Gnai1 G protein subunit alpha i1
Akr7a3 aldo-keto reductase family 7 member A3
Adcy8 adenylate cyclase 8
Ddt D-dopachrome tautomerase
Gstt2 glutathione S-transferase, theta 2
Notch2 notch receptor 2
Homer1 homer scaffold protein 1
Ugt2b37 UDP-glucuronosyltransferase 2 family, member 37
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Adcy4 adenylate cyclase 4
Aox1 aldehyde oxidase 1
Map2k2 mitogen activated protein kinase kinase 2
Aipl1 aryl hydrocarbon receptor-interacting protein-like 1
Pik3r3 phosphoinositide-3-kinase regulatory subunit 3
Ugt2a1 UDP glucuronosyltransferase family 2 member A1
Xiap X-linked inhibitor of apoptosis
Sult1b1 sulfotransferase family 1B member 1
Gstm5 glutathione S-transferase, mu 5
Adcy3 adenylate cyclase 3
Adcy5 adenylate cyclase 5
Mtpn myotrophin
Nr4a1 nuclear receptor subfamily 4, group A, member 1
Atf4 activating transcription factor 4
Atf2 activating transcription factor 2
Mmp14 matrix metallopeptidase 14
Nfkb1 nuclear factor kappa B subunit 1
Gstm7 glutathione S-transferase, mu 7
Ugt2b35 UDP glucuronosyltransferase 2 family, polypeptide B35
Rps6kb1 ribosomal protein S6 kinase B1
Dll1 delta like canonical Notch ligand 1
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Cacna1f calcium voltage-gated channel subunit alpha1 F
Klf4 Kruppel like factor 4
Zyx zyxin
Mapk1 mitogen activated protein kinase 1
Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1
Ptpn12 protein tyrosine phosphatase, non-receptor type 12
Septin2 septin 2
Abcc3 ATP binding cassette subfamily C member 3
Selenbp1 selenium binding protein 1
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C
Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62
Map2k1 mitogen activated protein kinase kinase 1
Ces2c carboxylesterase 2C
Mgst1 microsomal glutathione S-transferase 1
Ipmk inositol polyphosphate multikinase
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22
Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13
Stip1 stress-induced phosphoprotein 1
Ces2a carboxylesterase 2A
Trib3 tribbles pseudokinase 3
Drgx dorsal root ganglia homeobox
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18
Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2
Ugt2b15 UDP glucuronosyltransferase family 2 member B15
Slc17a3 solute carrier family 17 member 3
Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3
Ugt2b17 UDP glucuronosyltransferase family 2 member B17
Kpna1 karyopherin subunit alpha 1
Gpr39 G protein-coupled receptor 39
Mapkapk2 MAPK activated protein kinase 2
Cacybp calcyclin binding protein
Ugt2a3 UDP glucuronosyltransferase family 2 member A3
Mcm5 minichromosome maintenance complex component 5
Hras HRas proto-oncogene, GTPase
Carnmt1 carnosine N-methyltransferase 1
Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
Mgst2 microsomal glutathione S-transferase 2
Zbtb7b zinc finger and BTB domain containing 7B
Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3
Zdhhc22 zinc finger DHHC-type palmitoyltransferase 22
Hsp90aa1 heat shock protein 90 alpha family class A member 1
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Gsta4 glutathione S-transferase alpha 4
Hsp90ab1 heat shock protein 90 alpha family class B member 1
Fbxo11 F-box protein 11
Ugt2b10 UDP glucuronosyltransferase 2 family, polypeptide B10
Rela RELA proto-oncogene, NF-kB subunit
Hif1an hypoxia inducible factor 1 subunit alpha inhibitor
Nfkb2 nuclear factor kappa B subunit 2
Shoc2 SHOC2 leucine-rich repeat scaffold protein
Dll4 delta like canonical Notch ligand 4
Mlf2 myeloid leukemia factor 2
Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1
Fos Fos proto-oncogene, AP-1 transcription factor subunit
Creb3l3 cAMP responsive element binding protein 3-like 3
Paqr8 progestin and adipoQ receptor family member 8
Rps6ka6 ribosomal protein S6 kinase A6
Cdc6 cell division cycle 6
Kpna3 karyopherin subunit alpha 3
Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Heatr3 HEAT repeat containing 3
Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2
Kpna4 karyopherin subunit alpha 4
Lnpk lunapark, ER junction formation factor
Creb3l1 cAMP responsive element binding protein 3-like 1
Kpna6 karyopherin subunit alpha 6
Ptges3 prostaglandin E synthase 3
Ctdsp1 CTD small phosphatase 1
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Ptges3l1 prostaglandin E synthase 3-like 1
Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2
E2f1 E2F transcription factor 1
Ier2 immediate early response 2
Gsta5 glutathione S-transferase alpha 5
Gsta3 glutathione S-transferase alpha 3
Gstt3 glutathione S-transferase, theta 3
Gstm6 glutathione S-transferase, mu 6
Gstm4 glutathione S-transferase mu 4
Nrarp Notch-regulated ankyrin repeat protein
Gins1 GINS complex subunit 1
Gsta6 glutathione S-transferase alpha 6
RGD1559459 similar to Expressed sequence AI788959
Ugt1a5 UDP glucuronosyltransferase family 1 member A5
Fam199x family with sequence similarity 199, X-linked
Cfhr2 complement factor H-related 2
Tmem169 transmembrane protein 169
LOC100361492 cytochrome P450, family 2, subfamily c, polypeptide 55-like
LOC100361907 complement factor H-related protein B
LOC100364155 UDP-glucuronosyltransferase 2B2-like
LOC100911718 cytochrome P450 2C6-like
LOC120093077 cytochrome P450 2C6
Symbol Function*
STAT3 signal transducer and activator of transcription 3
STAT5A signal transducer and activator of transcription 5A
VEGFA vascular endothelial growth factor A
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
CHRNA7 cholinergic receptor nicotinic alpha 7 subunit
AIPL1 aryl hydrocarbon receptor interacting protein like 1
SLCO1B3 solute carrier organic anion transporter family member 1B3
UGT2B9*2 UDP Glucuronosyltransferase 2 family, polypeptide B9*2
CYP3A4 cytochrome P450 3A64
CYP2C8 cytochrome P450 family 2 subfamily C member 8
CYP1A1 cytochrome P450 family 1 subfamily A member 1
KPNA1 karyopherin subunit alpha 1
LOC693438 heat shock 60kDa protein 1 (chaperonin)-like
TRIB1 tribbles pseudokinase 1
KPNB1 karyopherin subunit beta 1
JAK2 Janus kinase 2
LOC694289 guanine nucleotide-binding protein G(s) subunit alpha
KLF5 Kruppel like factor 5
MYBL2 MYB proto-oncogene like 2
PAQR5 progestin and adipoQ receptor family member 5
ANGPTL3 angiopoietin like 3
UHRF1 ubiquitin like with PHD and ring finger domains 1
LOC695543 cocaine esterase
NR1H4 nuclear receptor subfamily 1 group H member 4
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
STUB1 STIP1 homology and U-box containing protein 1
HNF4G hepatocyte nuclear factor 4 gamma
GADD45G growth arrest and DNA damage inducible gamma
MGST2 microsomal glutathione S-transferase 2
RRBP1 ribosome binding protein 1
HSPD1 heat shock protein family D (Hsp60) member 1
OTC ornithine transcarbamylase
EGF epidermal growth factor
HRAS HRas proto-oncogene, GTPase
PIK3R1 phosphoinositide-3-kinase regulatory subunit 1
ATF2 activating transcription factor 2
HSP90B1 heat shock protein 90 beta family member 1
GSTM4 glutathione S-transferase mu 4
GSTM2 glutathione S-transferase mu 2
CDC6 cell division cycle 6
CHRNA9 cholinergic receptor nicotinic alpha 9 subunit
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
MGST1 microsomal glutathione S-transferase 1
GRB2 growth factor receptor bound protein 2
FOS Fos proto-oncogene, AP-1 transcription factor subunit
HSP90AB1 heat shock protein 90 alpha family class B member 1
APOA4 apolipoprotein A4
DUSP1 dual specificity phosphatase 1
RRM2 ribonucleotide reductase regulatory subunit M2
GNAI2 G protein subunit alpha i2
PLG plasminogen
B4GALT2 beta-1,4-galactosyltransferase 2
PJA2 praja ring finger ubiquitin ligase 2
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
KPNA6 karyopherin subunit alpha 6
KPNA7 karyopherin subunit alpha 7
HYOU1 hypoxia up-regulated 1
KRAS KRAS proto-oncogene, GTPase
ADCY6 adenylate cyclase 6
TAT tyrosine aminotransferase
MASP1 MBL associated serine protease 1
HSP90AA1 heat shock protein 90 alpha family class A member 1
RAD51 RAD51 recombinase
DUSP6 dual specificity phosphatase 6
UGT2B7 UDP glucuronosyltransferase family 2 member B7
AADAC arylacetamide deacetylase
LOC709132 UDP-glucuronosyltransferase 2B30
GSTA1 glutathione S-transferase alpha 1
LOC709234 UDP-glucuronosyltransferase 2B19
CACYBP calcyclin binding protein
ARRB2 arrestin beta 2
TK1 thymidine kinase 1
LOC709417 glutathione S-transferase A5
UGT2A3 UDP glucuronosyltransferase family 2 member A3
GSTA3 glutathione S-transferase alpha 3
BIRC5 baculoviral IAP repeat containing 5
PRKACB protein kinase cAMP-activated catalytic subunit beta
NR5A2 nuclear receptor subfamily 5 group A member 2
STAT5B signal transducer and activator of transcription 5B
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
IDH1 isocitrate dehydrogenase (NADP(+)) 1
NFKB1 nuclear factor kappa B subunit 1
LOC710412 UDP-glucuronosyltransferase 2B20
KLF6 Kruppel like factor 6
CDC25A cell division cycle 25A
KLF4 Kruppel like factor 4
FAM83B family with sequence similarity 83 member B
TM4SF4 transmembrane 4 L six family member 4
RBM22 RNA binding motif protein 22
PTGES3 prostaglandin E synthase 3
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
AOC1 amine oxidase copper containing 1
E2F1 E2F transcription factor 1
AHR aryl hydrocarbon receptor
ADCY4 adenylate cyclase 4
CREB3L2 cAMP responsive element binding protein 3 like 2
ITGB5 integrin subunit beta 5
GBA3 glucosylceramidase beta 3
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
RELA RELA proto-oncogene, NF-kB subunit
GSTO1 glutathione S-transferase omega 1
C8A complement C8 alpha chain
JUN Jun proto-oncogene, AP-1 transcription factor subunit
ITGB3 integrin subunit beta 3
KIAA2026 KIAA2026
SULT2A1 sulfotransferase family 2A member 1
BAD BCL2 associated agonist of cell death
LOC718141 UDP-glucuronosyltransferase 1-9
EPHX3 epoxide hydrolase 3
SPP2 secreted phosphoprotein 2
CHMP6 charged multivesicular body protein 6
HAO1 hydroxyacid oxidase 1
PRKACA protein kinase cAMP-activated catalytic subunit alpha
CCL16 C-C motif chemokine ligand 16
RGS19 regulator of G protein signaling 19
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
NUDC nuclear distribution C, dynein complex regulator
KDM5A lysine demethylase 5A
RPS6KB2 ribosomal protein S6 kinase B2
CTDNEP1 CTD nuclear envelope phosphatase 1
MAP2K2 mitogen-activated protein kinase kinase 2
CREB3L3 cAMP responsive element binding protein 3 like 3
LOC100424766 uncharacterized LOC100424766
GSTM5 glutathione S-transferase mu 5
ADRB1 adrenoceptor beta 1
LOC100427327 UDP-glucuronosyltransferase 2B23
LOC106992770 UDP-glucuronosyltransferase 1-8 pseudogene
CFHR2 complement factor H related 2
LOC107000278 uncharacterized LOC107000278
LOC114671445 UDP-glucuronosyltransferase 1-8-like
Symbol Function*
PRKACA protein kinase cAMP-activated catalytic subunit alpha
PGR progesterone receptor
ESR2 estrogen receptor 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
ADRB2 adrenoceptor beta 2
GNAS GNAS complex locus
EGFR epidermal growth factor receptor
NFKB1 nuclear factor kappa B subunit 1
AKT3 AKT serine/threonine kinase 3
PTGR1 prostaglandin reductase 1
ATF6B activating transcription factor 6 beta
LOC474938 glutathione S-transferase A2
GSTA4 glutathione S-transferase alpha 4
AHR aryl hydrocarbon receptor
PPP1R15A protein phosphatase 1 regulatory subunit 15A
SHKBP1 SH3KBP1 binding protein 1
DDA1 DET1 and DDB1 associated 1
DENND5A DENN domain containing 5A
KPNA3 karyopherin subunit alpha 3
FNDC3A fibronectin type III domain containing 3A
RB1 RB transcriptional corepressor 1
EPHX2 epoxide hydrolase 2
LOC477556 glutathione S-transferase theta-1
LOC477558 glutathione S-transferase theta-1
MGST1 microsomal glutathione S-transferase 1
GSTO1 glutathione S-transferase omega 1
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
GNAI1 G protein subunit alpha i1
MTOR mechanistic target of rapamycin kinase
KPNA1 karyopherin subunit alpha 1
ATF2 activating transcription factor 2
IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon
RXRG retinoid X receptor gamma
LOC479911 glutathione S-transferase Mu 3
LOC479912 glutathione S-transferase Mu 1
ADCY4 adenylate cyclase 4
KLF4 Kruppel like factor 4
RXRB retinoid X receptor beta
TIE1 tyrosine kinase with immunoglobulin like and EGF like domains 1
NOTCH2 notch receptor 2
GRB2 growth factor receptor bound protein 2
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
CACNA1D calcium voltage-gated channel subunit alpha1 D
FKBP8 FKBP prolyl isomerase 8
KLHL40 kelch like family member 40
LOC486404 glutathione S-transferase theta-4
NFKB2 nuclear factor kappa B subunit 2
KPNA6 karyopherin subunit alpha 6
DUSP1 dual specificity phosphatase 1
OSMR oncostatin M receptor
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
ADCY9 adenylate cyclase 9
CACNA1S calcium voltage-gated channel subunit alpha1 S
MAPKAPK2 MAPK activated protein kinase 2
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
FOS Fos proto-oncogene, AP-1 transcription factor subunit
AKT1 AKT serine/threonine kinase 1
PRKCA protein kinase C alpha
FMNL1 formin like 1
STAT3 signal transducer and activator of transcription 3
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
CREB3L2 cAMP responsive element binding protein 3 like 2
ADRB1 adrenoceptor beta 1
ARRB2 arrestin beta 2
DLL4 delta like canonical Notch ligand 4
MGST3 microsomal glutathione S-transferase 3
JUN Jun proto-oncogene, AP-1 transcription factor subunit
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
LOC610304 glutathione S-transferase A4-like
RPS6KB2 ribosomal protein S6 kinase B2
ERN1 endoplasmic reticulum to nucleus signaling 1
AHCYL1 adenosylhomocysteinase like 1
MAP2K2 mitogen-activated protein kinase kinase 2
EMC1 ER membrane protein complex subunit 1
RPS6KA2 ribosomal protein S6 kinase A2
PTGES3 prostaglandin E synthase 3
C18H11orf24 chromosome 18 C11orf24 homolog
EPHX3 epoxide hydrolase 3
APBA1 amyloid beta precursor protein binding family A member 1
PCDH18 protocadherin 18
GSTT2B glutathione S-transferase theta 2B
PRR16 proline rich 16
DLL1 delta like canonical Notch ligand 1
IGFBP3 insulin like growth factor binding protein 3
DDT D-dopachrome tautomerase
LOC100856518 glutathione S-transferase theta-3-like
LOC102153624 uncharacterized LOC102153624
TXNDC17 thioredoxin domain containing 17
LOC111094294 uncharacterized LOC111094294
NAA50 N-alpha-acetyltransferase 50, NatE catalytic subunit
Symbol Function*
MET MET proto-oncogene, receptor tyrosine kinase
BIRC5 baculoviral IAP repeat containing 5
BCL2 BCL2 apoptosis regulator
FOS Fos proto-oncogene, AP-1 transcription factor subunit
CYP1A2 cytochrome P450 family 1 subfamily A member 2
CYP1A1 cytochrome P450 family 1 subfamily A member 1
CACNA1S calcium voltage-gated channel subunit alpha1 S
LRCH1 leucine rich repeats and calponin homology domain containing 1
BCL2L2 BCL2 like 2
CHRNA3 cholinergic receptor nicotinic alpha 3 subunit
FGF2 fibroblast growth factor 2
NFKB1 nuclear factor kappa B subunit 1
KLF4 Kruppel like factor 4
AKT2 AKT serine/threonine kinase 2
EGFR epidermal growth factor receptor
CYP3A132 cytochrome P450 family 3 subfamily A member 132
CYP3A131 cytochrome P450 family 3 subfamily A member 131
TTN titin
POC1A POC1 centriolar protein A
RXRG retinoid X receptor gamma
MAP2K1 mitogen-activated protein kinase kinase 1
PHF3 PHD finger protein 3
USP4 ubiquitin specific peptidase 4
LOC101083370 glutathione S-transferase theta-1
LOC101083623 glutathione S-transferase theta-4-like
TNS1 tensin 1
GSTA4 glutathione S-transferase alpha 4
EPHX1 epoxide hydrolase 1
IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon
MAPK1 mitogen-activated protein kinase 1
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
MTMR3 myotubularin related protein 3
GNAI2 G protein subunit alpha i2
NUDT6 nudix hydrolase 6
ARG1 arginase 1
CHRNB4 cholinergic receptor nicotinic beta 4 subunit
PRKACA protein kinase cAMP-activated catalytic subunit alpha
STAT5B signal transducer and activator of transcription 5B
STAT5A signal transducer and activator of transcription 5A
RGS19 regulator of G protein signaling 19
ADCY6 adenylate cyclase 6
KCTD17 potassium channel tetramerization domain containing 17
EPHX2 epoxide hydrolase 2
LOC101092550 glutathione S-transferase theta-1-like
GNAI1 G protein subunit alpha i1
PIK3R3 phosphoinositide-3-kinase regulatory subunit 3
ARRB2 arrestin beta 2
EMP1 epithelial membrane protein 1
PON2 paraoxonase 2
VASP vasodilator stimulated phosphoprotein
CACNA1A calcium voltage-gated channel subunit alpha1 A
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
FAM241B family with sequence similarity 241 member B
STAT3 signal transducer and activator of transcription 3
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
LOC101096317 glutathione S-transferase A2
BCL6 BCL6 transcription repressor
CCDC68 coiled-coil domain containing 68
JUN Jun proto-oncogene, AP-1 transcription factor subunit
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
KPNA6 karyopherin subunit alpha 6
MTOR mechanistic target of rapamycin kinase
MTMR1 myotubularin related protein 1
E2F1 E2F transcription factor 1
MGST1 microsomal glutathione S-transferase 1
SELENBP1 selenium binding protein 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
CREB3L2 cAMP responsive element binding protein 3 like 2
ADCY5 adenylate cyclase 5
CCND3 cyclin D3
CYP2B6 cytochrome P450 family 2 subfamily B member 6
LOC105260134 cytochrome P450 2B11-like
LOC109492199 uncharacterized LOC109492199
URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
LOC111560471 glutathione S-transferase A2-like


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