KEGG 04623 Cytosolic DNA-sensing pathway
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa05169 Epstein-Barr virus infection 4
hsa04621 NOD-like receptor signaling pathway 3
hsa04622 RIG-I-like receptor signaling pathway 3
hsa04623 Cytosolic DNA-sensing pathway 3
hsa04625 C-type lectin receptor signaling pathway 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04623 Cytosolic DNA-sensing pathway 22
mmu04621 NOD-like receptor signaling pathway 17
mmu05164 Influenza A 17
mmu05169 Epstein-Barr virus infection 16
mmu05171 Coronavirus disease - COVID-19 15
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04623 Cytosolic DNA-sensing pathway 19
rno04621 NOD-like receptor signaling pathway 16
rno05164 Influenza A 15
rno05171 Coronavirus disease - COVID-19 14
rno05162 Measles 13
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04623 Cytosolic DNA-sensing pathway 12
gga05164 Influenza A 11
gga04620 Toll-like receptor signaling pathway 10
gga04621 NOD-like receptor signaling pathway 10
gga04060 Cytokine-cytokine receptor interaction 9
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre04623 Cytosolic DNA-sensing pathway 20
dre04621 NOD-like receptor signaling pathway 9
dre03020 RNA polymerase 9
dre05132 Salmonella infection 8
dre04622 RIG-I-like receptor signaling pathway 8
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04623 Cytosolic DNA-sensing pathway 19
mcc05164 Influenza A 13
mcc05171 Coronavirus disease - COVID-19 13
mcc04621 NOD-like receptor signaling pathway 11
mcc04620 Toll-like receptor signaling pathway 10
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04623 Cytosolic DNA-sensing pathway 20
cfa05171 Coronavirus disease - COVID-19 15
cfa05164 Influenza A 13
cfa04620 Toll-like receptor signaling pathway 12
cfa05169 Epstein-Barr virus infection 11
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04623 Cytosolic DNA-sensing pathway 21
fca04620 Toll-like receptor signaling pathway 13
fca05164 Influenza A 12
fca05171 Coronavirus disease - COVID-19 12
fca04621 NOD-like receptor signaling pathway 11
Gene list in the network
Symbol Function*
NFKB1 nuclear factor kappa B subunit 1
NFKBIB NFKB inhibitor beta
RELB RELB proto-oncogene, NF-kB subunit
IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon
Symbol Function*
Casp1 caspase 1
Casp8 caspase 8
Fas Fas (TNF receptor superfamily member 6)
Cxcl10 chemokine (C-X-C motif) ligand 10
Ikbkb inhibitor of kappaB kinase beta
Il18 interleukin 18
Il1b interleukin 1 beta
Irf9 interferon regulatory factor 9
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1
Polr2j polymerase (RNA) II (DNA directed) polypeptide J
Ccl4 chemokine (C-C motif) ligand 4
Trim26 tripartite motif-containing 26
Timm13 translocase of inner mitochondrial membrane 13
Irf7 interferon regulatory factor 7
Ccrl2 chemokine (C-C motif) receptor-like 2
Tyk2 tyrosine kinase 2
Adar adenosine deaminase, RNA-specific
Ikbke inhibitor of kappaB kinase epsilon
Ripk3 receptor-interacting serine-threonine kinase 3
Zbp1 Z-DNA binding protein 1
Polr2e polymerase (RNA) II (DNA directed) polypeptide E
Polr2l polymerase (RNA) II (DNA directed) polypeptide L
Rtp4 receptor transporter protein 4
Polr2f polymerase (RNA) II (DNA directed) polypeptide F
Tasl TLR adaptor interacting with endolysosomal SLC15A4
Sting1 stimulator of interferon response cGAMP interactor 1
Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58
Ddx58 DEAD/H box helicase 58
Aim2 absent in melanoma 2
Isg15 ISG15 ubiquitin-like modifier
Symbol Function*
Il1b interleukin 1 beta
Il6 interleukin 6
Mx1 MX dynamin like GTPase 1
Casp1 caspase 1
Ccl3 C-C motif chemokine ligand 3
Adar adenosine deaminase, RNA-specific
Nfkb1 nuclear factor kappa B subunit 1
Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta
Cxcl2 C-X-C motif chemokine ligand 2
Ccl4 C-C motif chemokine ligand 4
Zbp1 Z-DNA binding protein 1
Ripk3 receptor-interacting serine-threonine kinase 3
Pycard PYD and CARD domain containing
Mapkapk2 MAPK activated protein kinase 2
Irf7 interferon regulatory factor 7
Ddx58 DEXD/H-box helicase 58
Slfn2 schlafen family member 2
Aim2 absent in melanoma 2
Irf9 interferon regulatory factor 9
Rela RELA proto-oncogene, NF-kB subunit
Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Nfkb2 nuclear factor kappa B subunit 2
Usp18 ubiquitin specific peptidase 18
Rtp4 receptor (chemosensory) transporter protein 4
Polr3a RNA polymerase III subunit A
Polr3b RNA polymerase III subunit B
Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon
Epsti1 epithelial stromal interaction 1
Sting1 stimulator of interferon response cGAMP interactor 1
Cyth4 cytohesin 4
Nol11 nucleolar protein 11
Tyk2 tyrosine kinase 2
Symbol Function*
TNFRSF6B TNF receptor superfamily member 6b
IL1B interleukin 1, beta
IL6 interleukin 6
CCL4 C-C motif chemokine ligand 4
POLR2F RNA polymerase II subunit F
LOC395551 chemokine (C-C motif) ligand 4
IL8L1 interleukin 8-like 1
NFKB1 nuclear factor kappa B subunit 1
NFKBIA NFKB inhibitor alpha
IL8L2 interleukin 8-like 2
CCLL4 chemokine-like ligand 4
CCL5 C-C motif chemokine ligand
TLR15 toll-like receptor 15
TMEM173 transmembrane protein 173
ADAR adenosine deaminase, RNA specific
POLR2L RNA polymerase II subunit L
NDUFA1 NADH:ubiquinone oxidoreductase subunit A1
PMLL promyelocytic leukemia-like
STAT2 signal transducer and activator of transcription 2
IFNKL1 interferon kappa-like 1
IL18BP interleukin 18 binding protein
Symbol Function*
pycard PYD and CARD domain containing
caspa caspase a
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
polr3c polymerase (RNA) III (DNA directed) polypeptide C
polr3d polymerase (RNA) III (DNA directed) polypeptide D
prmt7 protein arginine methyltransferase 7
polr1c RNA polymerase I and III subunit C
irf7 interferon regulatory factor 7
snrpe small nuclear ribonucleoprotein polypeptide E
nfkbiaa nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
rela v-rel avian reticuloendotheliosis viral oncogene homolog A
hgh1 HGH1 homolog (S. cerevisiae)
polr3k polymerase (RNA) III (DNA directed) polypeptide K
polr1d RNA polymerase I and III subunit D
polr3gla RNA polymerase III subunit GL a
polr2h RNA polymerase II, I and III subunit H
polr2l RNA polymerase II, I and III subunit L
trmt112 tRNA methyltransferase activator subunit 11-2
si:dkeyp-118h9.7 si:dkeyp-118h9.7
cgasa cyclic GMP-AMP synthase a
ikbkb inhibitor of nuclear factor kappa B kinase subunit beta
nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
ripk1l receptor (TNFRSF)-interacting serine-threonine kinase 1, like
nxt2 nuclear transport factor 2-like export factor 2
elp5 elongator acetyltransferase complex subunit 5
polr2k RNA polymerase II, I and III subunit K
ddx58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
Symbol Function*
IL18 interleukin 18
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CXCL10 C-X-C motif chemokine ligand 10
CCL3 chemokine (C-C motif) ligand 3
LOC694538 guanylate-binding protein 1
NFKBIB NFKB inhibitor beta
IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon
ACOD1 aconitate decarboxylase 1
PRDM1 PR/SET domain 1
PLEK pleckstrin
POLR3B RNA polymerase III subunit B
DDX58 DExD/H-box helicase 58
IKBKB inhibitor of nuclear factor kappa B kinase subunit beta
IL1B interleukin 1 beta
IL6 interleukin 6
LOC706568 caspase-1
PTGDR prostaglandin D2 receptor
EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2
NFKB1 nuclear factor kappa B subunit 1
FMNL3 formin like 3
NOLC1 nucleolar and coiled-body phosphoprotein 1
LOC714689 nuclear factor NF-kappa-B p100 subunit
SLFN12 schlafen family member 12
RIPK3 receptor interacting serine/threonine kinase 3
CGAS cyclic GMP-AMP synthase
RNF213 ring finger protein 213
ADAR adenosine deaminase RNA specific
POLR3A RNA polymerase III subunit A
LOC100426388 caspase-1-like
LOC100426632 C-C motif chemokine 4
LOC100430627 C-C motif chemokine 4
Symbol Function*
CCL5 C-C motif chemokine ligand 5
RPS18 ribosomal protein S18
MX1 MX dynamin like GTPase 1
CXCL8 C-X-C motif chemokine ligand 8
IL1B interleukin 1 beta
IL6 interleukin 6
NFKB1 nuclear factor kappa B subunit 1
CCL4 chemokine (C-C motif) ligand 4
CCL3 chemokine (C-C motif) ligand 3
POLR3B RNA polymerase III subunit B
RPS9 ribosomal protein S9
IRF3 interferon regulatory factor 3
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
PDCD11 programmed cell death 11
CXCL10 C-X-C motif chemokine ligand 10
POLR2H RNA polymerase II, I and III subunit H
IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon
MVP major vault protein
NFKBIA NFKB inhibitor alpha
RELB RELB proto-oncogene, NF-kB subunit
NFKB2 nuclear factor kappa B subunit 2
POLR3G RNA polymerase III subunit G
CGAS cyclic GMP-AMP synthase
ZBP1 Z-DNA binding protein 1
BLM BLM RecQ like helicase
POLR1D RNA polymerase I and III subunit D
DDX58 DExD/H-box helicase 58
ISG15 ISG15 ubiquitin like modifier
ADAR adenosine deaminase RNA specific
POLR3D RNA polymerase III subunit D
LOC111092404 DNA-directed RNA polymerases I and III subunit RPAC2
IRF7 interferon regulatory factor 7
XAF1 XIAP associated factor 1
Symbol Function*
CCL5 C-C motif chemokine ligand 5
CXCL8 C-X-C motif chemokine ligand 8
IL1B interleukin 1 beta
IKBKB inhibitor of nuclear factor kappa B kinase subunit beta
NFKB1 nuclear factor kappa B subunit 1
LOC100302541 chemokine (C-C motif) ligand 4-like
LOC101080774 interferon regulatory factor 4-like
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4
R3HCC1L R3H domain and coiled-coil containing 1 like
LOC101082677 guanylate-binding protein 6
IRF7 interferon regulatory factor 7
POLR2H RNA polymerase II, I and III subunit H
ADAR adenosine deaminase RNA specific
IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon
RIPK1 receptor interacting serine/threonine kinase 1
POLR1C RNA polymerase I and III subunit C
POLR3K RNA polymerase III subunit K
NFKBIA NFKB inhibitor alpha
STING1 stimulator of interferon response cGAMP interactor 1
RHBDD1 rhomboid domain containing 1
STX11 syntaxin 11
ZBP1 Z-DNA binding protein 1
RIBC2 RIB43A domain with coiled-coils 2
DDX58 DExD/H-box helicase 58
COA4 cytochrome c oxidase assembly factor 4 homolog
RIPK3 receptor interacting serine/threonine kinase 3
CGAS cyclic GMP-AMP synthase
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
TREX1 three prime repair exonuclease 1
OASL 2'-5'-oligoadenylate synthetase like
IFIH1 interferon induced with helicase C domain 1
CXCL11 C-X-C motif chemokine ligand 11
CXCL10 C-X-C motif chemokine ligand 10
CXCL9 C-X-C motif chemokine ligand 9
LGALS8 galectin 8
POLR2F RNA polymerase II, I and III subunit F


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