KEGG 04216 Ferroptosis
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04216 Ferroptosis 20
hsa04217 Necroptosis 4
hsa04978 Mineral absorption 4
hsa00061 Fatty acid biosynthesis 3
hsa00071 Fatty acid degradation 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04216 Ferroptosis 17
mmu04978 Mineral absorption 6
mmu01240 Biosynthesis of cofactors 5
mmu05200 Pathways in cancer 4
mmu05225 Hepatocellular carcinoma 4
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04216 Ferroptosis 12
rno04978 Mineral absorption 4
rno04217 Necroptosis 4
rno05208 Chemical carcinogenesis - reactive oxygen species 3
rno00270 Cysteine and methionine metabolism 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04216 Ferroptosis 12
gga00480 Glutathione metabolism 4
gga01240 Biosynthesis of cofactors 3
gga04137 Mitophagy - animal 2
gga04140 Autophagy - animal 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre04216 Ferroptosis 24
dre04217 Necroptosis 7
dre04137 Mitophagy - animal 4
dre00480 Glutathione metabolism 4
dre04115 p53 signaling pathway 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04216 Ferroptosis 10
mcc05010 Alzheimer disease 4
mcc04978 Mineral absorption 3
mcc04066 HIF-1 signaling pathway 3
mcc05012 Parkinson disease 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04216 Ferroptosis 12
cfa04978 Mineral absorption 4
cfa00480 Glutathione metabolism 4
cfa00270 Cysteine and methionine metabolism 3
cfa01240 Biosynthesis of cofactors 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04216 Ferroptosis 11
fca04978 Mineral absorption 3
fca00270 Cysteine and methionine metabolism 2
fca00480 Glutathione metabolism 2
fca01240 Biosynthesis of cofactors 2
Gene list in the network
Symbol Function*
ACSL1 acyl-CoA synthetase long chain family member 1
ACSL3 acyl-CoA synthetase long chain family member 3
ACSL4 acyl-CoA synthetase long chain family member 4
FTH1 ferritin heavy chain 1
FTL ferritin light chain
GCLC glutamate-cysteine ligase catalytic subunit
GCLM glutamate-cysteine ligase modifier subunit
HMOX1 heme oxygenase 1
SLC11A2 solute carrier family 11 member 2
PCBP1 poly(rC) binding protein 1
PCBP2 poly(rC) binding protein 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC3A2 solute carrier family 3 member 2
SREBF1 sterol regulatory element binding transcription factor 1
TFRC transferrin receptor
VDAC2 voltage dependent anion channel 2
NCOA4 nuclear receptor coactivator 4
SQSTM1 sequestosome 1
NAMPT nicotinamide phosphoribosyltransferase
LPCAT3 lysophosphatidylcholine acyltransferase 3
EIF1 eukaryotic translation initiation factor 1
CTDNEP1 CTD nuclear envelope phosphatase 1
SLC7A11 solute carrier family 7 member 11
GHITM growth hormone inducible transmembrane protein
SLC39A8 solute carrier family 39 member 8
ATP13A3 ATPase 13A3
MAP1LC3B microtubule associated protein 1 light chain 3 beta
SRXN1 sulfiredoxin 1
SLC7A11-AS1 SLC7A11 antisense RNA 1
Symbol Function*
C3 complement component 3
Cp ceruloplasmin
Fth1 ferritin heavy polypeptide 1
Ftl1 ferritin light polypeptide 1
Gclc glutamate-cysteine ligase, catalytic subunit
Gclm glutamate-cysteine ligase, modifier subunit
Lpcat3 lysophosphatidylcholine acyltransferase 3
Gss glutathione synthetase
Hmox1 heme oxygenase 1
Rdh11 retinol dehydrogenase 11
Nqo1 NAD(P)H dehydrogenase, quinone 1
Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Trf transferrin
Tfrc transferrin receptor
Trp53 transformation related protein 53
Pcbp1 poly(rC) binding protein 1
Txnrd1 thioredoxin reductase 1
Acsl4 acyl-CoA synthetase long-chain family member 4
Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1
Acsl3 acyl-CoA synthetase long-chain family member 3
Srxn1 sulfiredoxin 1 homolog (S. cerevisiae)
Sf3b4 splicing factor 3b, subunit 4
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
Blvrb biliverdin reductase B (flavin reductase (NADPH))
Acsl5 acyl-CoA synthetase long-chain family member 5
Ftl1-ps2 ferritin light polypeptide, pseudogene 2
Symbol Function*
Hmox1 heme oxygenase 1
Gclc glutamate-cysteine ligase, catalytic subunit
Fth1 ferritin heavy chain 1
Asns asparagine synthetase (glutamine-hydrolyzing)
Ftl1 ferritin light chain 1
Gclm glutamate cysteine ligase, modifier subunit
Slc3a2 solute carrier family 3 member 2
Slc7a5 solute carrier family 7 member 5
Vdac2 voltage-dependent anion channel 2
Vdac3 voltage-dependent anion channel 3
Slc40a1 solute carrier family 40 member 1
Srxn1 sulfiredoxin 1
Slc7a11 solute carrier family 7 member 11
Pcbp2 poly(rC) binding protein 2
Pcbp1 poly(rC) binding protein 1
Symbol Function*
SAT1 spermidine/spermine N1-acetyltransferase 1
GPX4 glutathione peroxidase 4
FTH1 ferritin heavy chain 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAP1LC3A microtubule associated protein 1 light chain 3 alpha
PGD phosphogluconate dehydrogenase
SDR16C5 short chain dehydrogenase/reductase family 16C member 5
GCLC glutamate-cysteine ligase catalytic subunit
NCOA4 nuclear receptor coactivator 4
ACSL5 acyl-CoA synthetase long-chain family member 5
SLC40A1 solute carrier family 40 member 1
GCLM glutamate-cysteine ligase modifier subunit
ACSL3 acyl-CoA synthetase long chain family member 3
CREBL2 cAMP responsive element binding protein like 2
MAP1LC3B microtubule associated protein 1 light chain 3 beta
SLC25A13 solute carrier family 25 member 13
Symbol Function*
tp53 tumor protein p53
baxa BCL2 associated X, apoptosis regulator a
slc40a1 solute carrier family 40 member 1
slc4a1a solute carrier family 4 member 1a (Diego blood group)
abhd17aa abhydrolase domain containing 17A, depalmitoylase a
map1lc3b microtubule-associated protein 1 light chain 3 beta
gclc glutamate-cysteine ligase, catalytic subunit
gclm glutamate-cysteine ligase, modifier subunit
gpx4a glutathione peroxidase 4a
selenop selenoprotein P
slc3a2b solute carrier family 3 member 2b
hmox1b heme oxygenase 1b
map1lc3a microtubule-associated protein 1 light chain 3 alpha
sat1a.2 spermidine/spermine N1-acetyltransferase 1a, duplicate 2
fthl27 ferritin, heavy polypeptide-like 27
gss glutathione synthetase
tfr1a transferrin receptor 1a
fthl31 ferritin, heavy polypeptide-like 31
fthl30 ferritin, heavy polypeptide-like 30
sat1a.1 spermidine/spermine N1-acetyltransferase 1a, duplicate 1
sat1b spermidine/spermine N1-acetyltransferase 1b
hmox1a heme oxygenase 1a
gabarapb GABA(A) receptor-associated protein b
slc3a2a solute carrier family 3 member 2a
slc39a14 solute carrier family 39 member 14
fthl28 ferritin, heavy polypeptide-like 28
slc7a8a solute carrier family 7 member 8a
zgc:173594 zgc:173594
fthl29 ferritin, heavy polypeptide-like 29
steap3 STEAP family member 3, metalloreductase
Symbol Function*
SERPINA3 serpin family A member 3
SLC11A2 solute carrier family 11 member 2
ACSL5 acyl-CoA synthetase long chain family member 5
CYBB cytochrome b-245 beta chain
CASP7 caspase 7
SAT1 spermidine/spermine N1-acetyltransferase 1
GOLPH3 golgi phosphoprotein 3
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PCBP1 poly(rC) binding protein 1
SLC39A8 solute carrier family 39 member 8
CP ceruloplasmin
GCLM glutamate-cysteine ligase modifier subunit
HMOX1 heme oxygenase 1
TF transferrin
Symbol Function*
LOC403631 ferritin heavy chain 1
GSS glutathione synthetase
HMOX1 heme oxygenase 1
ATG7 autophagy related 7
RFT1 RFT1 homolog
FTL ferritin light chain
SLC40A1 solute carrier family 40 member 1
ACSL3 acyl-CoA synthetase long chain family member 3
ACSL4 acyl-CoA synthetase long chain family member 4
SLC3A2 solute carrier family 3 member 2
SLC7A11 solute carrier family 7 member 11
CTSB cathepsin B
GCLC glutamate-cysteine ligase catalytic subunit
SC5D sterol-C5-desaturase
GCLM glutamate-cysteine ligase modifier subunit
FTH1 ferritin heavy chain 1
CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1
Symbol Function*
FTL ferritin light chain
LOC101081158 ceruloplasmin
GCLM glutamate-cysteine ligase modifier subunit
CTSB cathepsin B
LOC101085148 serotransferrin
MARCHF5 membrane associated ring-CH-type finger 5
PCBP2 poly(rC) binding protein 2
LOC101087599 inhibitor of carbonic anhydrase-like
ACSL4 acyl-CoA synthetase long chain family member 4
PCBP1 poly(rC) binding protein 1
GCLC glutamate-cysteine ligase catalytic subunit
SLC39A8 solute carrier family 39 member 8
ACSL5 acyl-CoA synthetase long chain family member 5


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