KEGG 03460 Fanconi anemia pathway
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) dme(Fly) cel(Nematoda) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa03460 Fanconi anemia pathway 26
hsa03440 Homologous recombination 10
hsa01524 Platinum drug resistance 3
hsa05200 Pathways in cancer 3
hsa03420 Nucleotide excision repair 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu03460 Fanconi anemia pathway 22
mmu03440 Homologous recombination 10
mmu05224 Breast cancer 2
mmu05200 Pathways in cancer 2
mmu05212 Pancreatic cancer 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno03460 Fanconi anemia pathway 22
rno03440 Homologous recombination 9
rno04110 Cell cycle 5
rno04115 p53 signaling pathway 4
rno04218 Cellular senescence 4
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga03460 Fanconi anemia pathway 30
gga03440 Homologous recombination 11
gga03030 DNA replication 6
gga04110 Cell cycle 4
gga03420 Nucleotide excision repair 4
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre03460 Fanconi anemia pathway 31
dre03440 Homologous recombination 14
dre03030 DNA replication 8
dre03420 Nucleotide excision repair 6
dre03430 Mismatch repair 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dme03460 Fanconi anemia pathway 12
dme03440 Homologous recombination 7
dme03430 Mismatch repair 6
dme03030 DNA replication 5
dme03420 Nucleotide excision repair 4
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cel03460 Fanconi anemia pathway 12
cel03440 Homologous recombination 3
cel03420 Nucleotide excision repair 2
cel04150 mTOR signaling pathway 2
cel03430 Mismatch repair 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc03460 Fanconi anemia pathway 19
mcc03440 Homologous recombination 9
mcc01524 Platinum drug resistance 3
mcc03430 Mismatch repair 3
mcc05200 Pathways in cancer 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa03460 Fanconi anemia pathway 19
cfa03440 Homologous recombination 8
cfa03430 Mismatch repair 3
cfa01524 Platinum drug resistance 2
cfa05224 Breast cancer 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca03460 Fanconi anemia pathway 20
fca03440 Homologous recombination 6
fca04110 Cell cycle 3
fca05200 Pathways in cancer 2
fca05212 Pancreatic cancer 2
Gene list in the network
Symbol Function*
ATR ATR serine/threonine kinase
BLM BLM RecQ like helicase
BRCA1 BRCA1 DNA repair associated
BRCA2 BRCA2 DNA repair associated
ERCC4 ERCC excision repair 4, endonuclease catalytic subunit
FANCA FA complementation group A
FANCD2 FA complementation group D2
FANCE FA complementation group E
FANCB FA complementation group B
FANCG FA complementation group G
MLH1 mutL homolog 1
RAD51 RAD51 recombinase
REV3L REV3 like, DNA directed polymerase zeta catalytic subunit
RPA1 replication protein A1
RPA3 replication protein A3
RRM1 ribonucleotide reductase catalytic subunit M1
TCF19 transcription factor 19
TOP3A DNA topoisomerase III alpha
USP1 ubiquitin specific peptidase 1
CDC45 cell division cycle 45
RAD54L RAD54 like
CASP8AP2 caspase 8 associated protein 2
TRAIP TRAF interacting protein
WDHD1 WD repeat and HMG-box DNA binding protein 1
CNOT10 CCR4-NOT transcription complex subunit 10
UBE2T ubiquitin conjugating enzyme E2 T
DTL denticleless E3 ubiquitin protein ligase homolog
GINS2 GINS complex subunit 2
FANCI FA complementation group I
BIRC6 baculoviral IAP repeat containing 6
WDR48 WD repeat domain 48
PALB2 partner and localizer of BRCA2
ATAD5 ATPase family AAA domain containing 5
RMI1 RecQ mediated genome instability 1
CDT1 chromatin licensing and DNA replication factor 1
DYNC2I2 dynein 2 intermediate chain 2
FAAP24 FA core complex associated protein 24
MTFR2 mitochondrial fission regulator 2
SMYD4 SET and MYND domain containing 4
RMI2 RecQ mediated genome instability 2
EME1 essential meiotic structure-specific endonuclease 1
CENPS centromere protein S
Symbol Function*
Bard1 BRCA1 associated RING domain 1
Blm Bloom syndrome, RecQ like helicase
Brca1 breast cancer 1, early onset
Brca2 breast cancer 2, early onset
Fanca Fanconi anemia, complementation group A
Fancc Fanconi anemia, complementation group C
Pms2 PMS1 homolog2, mismatch repair system component
Rad51 RAD51 recombinase
Rad51ap1 RAD51 associated protein 1
Rad54l RAD54 like (S. cerevisiae)
Top3a topoisomerase (DNA) III alpha
Traip TRAF-interacting protein
Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4
Fancg Fanconi anemia, complementation group G
Ube2t ubiquitin-conjugating enzyme E2T
Cenps centromere protein S
Ticrr TOPBP1-interacting checkpoint and replication regulator
Fancm Fanconi anemia, complementation group M
B3galt6 UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
Eme2 essential meiotic structure-specific endonuclease subunit 2
Kntc1 kinetochore associated 1
Fanci Fanconi anemia, complementation group I
Fancd2 Fanconi anemia, complementation group D2
Nrde2 nrde-2 necessary for RNA interference, domain containing
Wdhd1 WD repeat and HMG-box DNA binding protein 1
Rmi2 RecQ mediated genome instability 2
Zranb3 zinc finger, RAN-binding domain containing 3
Wdr62 WD repeat domain 62
Palb2 partner and localizer of BRCA2
Fancb Fanconi anemia, complementation group B
Atad5 ATPase family, AAA domain containing 5
Brip1 BRCA1 interacting protein C-terminal helicase 1
Zfp473 zinc finger protein 473
Eme1 essential meiotic structure-specific endonuclease 1
Fancf Fanconi anemia, complementation group F
Symbol Function*
Nxf1 nuclear RNA export factor 1
Rpa2 replication protein A2
Chek2 checkpoint kinase 2
Polk DNA polymerase kappa
Mis18a MIS18 kinetochore protein A
Pms2 PMS1 homolog 2, mismatch repair system component
Cenpl centromere protein L
Pbk PDZ binding kinase
Mcm5 minichromosome maintenance complex component 5
Palb2 partner and localizer of BRCA2
Atm ATM serine/threonine kinase
Atrip ATR interacting protein
Slx4 SLX4 structure-specific endonuclease subunit
Atad5 ATPase family, AAA domain containing 5
Kntc1 kinetochore associated 1
Pole DNA polymerase epsilon, catalytic subunit
Wdhd1 WD repeat and HMG-box DNA binding protein 1
Rmi1 RecQ mediated genome instability 1
Blm BLM RecQ like helicase
Fancd2 FA complementation group D2
Usp1 ubiquitin specific peptidase 1
Fancm FA complementation group M
Cnot10 CCR4-NOT transcription complex, subunit 10
Polh DNA polymerase eta
Brca2 BRCA2, DNA repair associated
Brip1 BRCA1 interacting helicase 1
Ube2t ubiquitin-conjugating enzyme E2T
Cenpn centromere protein N
Fanca FA complementation group A
Ccne2 cyclin E2
Chaf1a chromatin assembly factor 1 subunit A
Brca1 BRCA1, DNA repair associated
Rmi2 RecQ mediated genome instability 2
Rad51c RAD51 paralog C
LOC498265 similar to hypothetical protein FLJ10706
Nsl1 NSL1 component of MIS12 kinetochore complex
Rad51 RAD51 recombinase
Atr ATR serine/threonine kinase
Rad51ap1 RAD51 associated protein 1
Fancg FA complementation group G
Fanci FA complementation group I
Symbol Function*
BRCA1 BRCA1 DNA repair associated
BRCA2 BRCA2, DNA repair associated
FANCG Fanconi anemia complementation group G
HES4 hes family bHLH transcription factor 4
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RAD51 RAD51 recombinase
FAN1 FANCD2/FANCI-associated nuclease 1
FANCI Fanconi anemia complementation group I
BLM Bloom syndrome RecQ like helicase
FAAP24 Fanconi anemia core complex associated protein 24
FANCA Fanconi anemia complementation group A
FANCD2 Fanconi anemia complementation group D2
HAUS1 HAUS augmin like complex subunit 1
TOP3A topoisomerase (DNA) III alpha
SLX4 SLX4 structure-specific endonuclease subunit homolog
TOP3B topoisomerase (DNA) III beta
KNTC1 kinetochore associated 1
POLE DNA polymerase epsilon, catalytic subunit
RPA1 replication protein A1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
POLR3B RNA polymerase III subunit B
FANCB Fanconi anemia complementation group B
CSE1L chromosome segregation 1 like
RPA2 replication protein A2
FANCE Fanconi anemia complementation group E
MTBP MDM2 binding protein
RPA3 replication protein A3
RTTN rotatin
UBE2T ubiquitin conjugating enzyme E2 T
FANCL Fanconi anemia complementation group L
PBK PDZ binding kinase
EME1 essential meiotic structure-specific endonuclease 1
CEP135 centrosomal protein 135
DNA2 DNA replication helicase/nuclease 2
MKI67 marker of proliferation Ki-67
TEDC1 tubulin epsilon and delta complex 1
CDC7 cell division cycle 7
ATR ATR serine/threonine kinase
GINS1 GINS complex subunit 1
MCM4 minichromosome maintenance complex component 4
FANCC Fanconi anemia complementation group C
CLSPN claspin
ZGRF1 zinc finger GRF-type containing 1
HES1 hes family bHLH transcription factor 1
DUT deoxyuridine triphosphatase
CENPS centromere protein S
NDC1 NDC1 transmembrane nucleoporin
FAM110A family with sequence similarity 110 member A
NCAPG2 non-SMC condensin II complex subunit G2
FANCF Fanconi anemia, complementation group F
CENPX centromere protein X
PMS2 PMS1 homolog 2, mismatch repair system component
Symbol Function*
her6 hairy-related 6
dnmt1 DNA (cytosine-5-)-methyltransferase 1
pcna proliferating cell nuclear antigen
rpa2 replication protein A2
tyms thymidylate synthetase
her9 hairy-related 9
pola1 polymerase (DNA directed), alpha 1
pask PAS domain containing serine/threonine kinase
fanci FA complementation group I
ercc4 excision repair cross-complementation group 4
rpa1 replication protein A1
nrarpa NOTCH regulated ankyrin repeat protein a
fen1 flap structure-specific endonuclease 1
rmi1 RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
rpa3 replication protein A3
mlh1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
rad54l RAD54 like
fancd2 FA complementation group D2
fancg FA complementation group G
fancl FA complementation group L
rad51 RAD51 recombinase
cdc45 CDC45 cell division cycle 45 homolog (S. cerevisiae)
prim2 DNA primase subunit 2
topbp1 DNA topoisomerase II binding protein 1
xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1
rad51c RAD51 paralog C
haus5 HAUS augmin-like complex, subunit 5
anapc4 anaphase promoting complex subunit 4
rbbp8 retinoblastoma binding protein 8
pole polymerase (DNA directed), epsilon
gins2 GINS complex subunit 2
mcm9 minichromosome maintenance 9 homologous recombination repair factor
eme1 essential meiotic structure-specific endonuclease 1
mutyh mutY DNA glycosylase
haus6 HAUS augmin-like complex, subunit 6
faap24 FA core complex associated protein 24
sfi1 SFI1 centrin binding protein
top3a DNA topoisomerase III alpha
rad54b RAD54 homolog B
pms2 PMS1 homolog 2, mismatch repair system component
fan1 FANCD2 and FANCI associated nuclease 1
brca2 BRCA2 DNA repair associated
cenps centromere protein S
blm BLM RecQ like helicase
polh polymerase (DNA directed), eta
fanca FA complementation group A
fancc FA complementation group C
fancf FA complementation group F
smyd4 SET and MYND domain containing 4
zgc:153352 zgc:153352
dclre1b DNA cross-link repair 1B
ube2t ubiquitin-conjugating enzyme E2T (putative)
telo2 TEL2, telomere maintenance 2, homolog (S. cerevisiae)
brip1 BRCA1 interacting helicase 1
faap100 FA core complex associated protein 100
fancm FA complementation group M
wdr90 WD repeat domain 90
anapc2 anaphase promoting complex subunit 2
fancb FA complementation group B
Symbol Function*
RPA3 Replication protein A3
Marcal1 Marcal1
dgt2 dim gamma-tubulin 2
Top3alpha Topoisomerase 3alpha
RPA2 Replication protein A2
Mlh1 Mlh1
FANCI Fanconi anemia complementation group I
mms4 Methyl methanesulfonate sensitivity 4
Pms2 Pms2
rad50 rad50
RfC4 Replication factor C subunit 4
DNApol-eta DNA polymerase eta
RpA-70 Replication Protein A 70
DNApol-alpha73 DNA polymerase alpha 73kD subunit
spn-A spindle A
DNApol-zeta DNA polymerase zeta catalytic subunit
Irbp Inverted repeat-binding protein
Fancd2 Fancd2
Symbol Function*
mus-81 ERCC4 domain-containing protein
slx-1 Structure-specific endonuclease subunit SLX1 homolog
ercc-1 ERCC (DNA excision repair protein) homolog
rtel-1 Regulator of telomere elongation helicase 1 homolog
wrn-1 putative Werner syndrome ATP-dependent helicase homolog 1
rev-1 DNA repair protein REV1
xpf-1 ERCC4 domain-containing protein
Y48C3A.14 DNA topoisomerase
rev-3 DNA polymerase
clk-2 Telomere length regulation protein clk-2
top-3 DNA topoisomerase 3
mlh-1 DNA_mis_repair domain-containing protein
fan-1 Fanconi-associated nuclease;Fanconi-associated nuclease 1 homolog
R10H10.7 Uncharacterized protein
pms-2 PMS (Post Meiotic Segregation) family
Symbol Function*
NCAPG2 non-SMC condensin II complex subunit G2
REV3L REV3 like, DNA directed polymerase zeta catalytic subunit
THOC1 THO complex 1
MLH1 mutL homolog 1
KIF11 kinesin family member 11
FANCI FA complementation group I
PALB2 partner and localizer of BRCA2
GINS4 GINS complex subunit 4
BLM BLM RecQ like helicase
RAD51 RAD51 recombinase
REV1 REV1 DNA directed polymerase
SASS6 SAS-6 centriolar assembly protein
RMI2 RecQ mediated genome instability 2
FANCB FA complementation group B
BRIP1 BRCA1 interacting helicase 1
BRCA1 BRCA1 DNA repair associated
ERCC4 ERCC excision repair 4, endonuclease catalytic subunit
FAAP100 FA core complex associated protein 100
LOC716070 Fanconi anemia group D2 protein
HEXD hexosaminidase D
CEP350 centrosomal protein 350
RPA2 replication protein A2
MCM8 minichromosome maintenance 8 homologous recombination repair factor
RPA1 replication protein A1
BRCA2 BRCA2 DNA repair associated
EME2 essential meiotic structure-specific endonuclease subunit 2
EME1 essential meiotic structure-specific endonuclease 1
Symbol Function*
BRCA1 BRCA1 DNA repair associated
BRCA2 BRCA2 DNA repair associated
RRM1 ribonucleotide reductase catalytic subunit M1
MLH1 mutL homolog 1
WDR48 WD repeat domain 48
FANCM FA complementation group M
SMC2 structural maintenance of chromosomes 2
FANCD2 FA complementation group D2
CENPJ centromere protein J
ALKBH8 alkB homolog 8, tRNA methyltransferase
EME2 essential meiotic structure-specific endonuclease subunit 2
WDHD1 WD repeat and HMG-box DNA binding protein 1
EME1 essential meiotic structure-specific endonuclease 1
BRIP1 BRCA1 interacting helicase 1
HROB homologous recombination factor with OB-fold
MASTL microtubule associated serine/threonine kinase like
FANCC FA complementation group C
FAAP100 FA core complex associated protein 100
TEPSIN TEPSIN adaptor related protein complex 4 accessory protein
PALB2 partner and localizer of BRCA2
FANCA FA complementation group A
ERI2 ERI1 exoribonuclease family member 2
C7H1orf112 chromosome 7 C1orf112 homolog
POLI DNA polymerase iota
RMI1 RecQ mediated genome instability 1
BLM BLM RecQ like helicase
RPA1 replication protein A1
FANCI FA complementation group I
RPA2 replication protein A2
Symbol Function*
BRCA2 BRCA2 DNA repair associated
KIF20B kinesin family member 20B
USP1 ubiquitin specific peptidase 1
MMS22L MMS22 like, DNA repair protein
ATAD2 ATPase family AAA domain containing 2
CEP57 centrosomal protein 57
TELO2 telomere maintenance 2
NCAPG non-SMC condensin I complex subunit G
ATR ATR serine/threonine kinase
FANCC FA complementation group C
POLH DNA polymerase eta
RAD51 RAD51 recombinase
MCM4 minichromosome maintenance complex component 4
PALB2 partner and localizer of BRCA2
FANCI FA complementation group I
EME1 essential meiotic structure-specific endonuclease 1
BRIP1 BRCA1 interacting helicase 1
FANCG FA complementation group G
FANCD2 FA complementation group D2
NCAPH non-SMC condensin I complex subunit H
FANCB FA complementation group B
SLX4 SLX4 structure-specific endonuclease subunit
LOC101096495 centromere protein S
FANCL FA complementation group L
STIL STIL centriolar assembly protein
FAAP100 FA core complex associated protein 100
DDX11 DEAD/H-box helicase 11
PLK1 polo like kinase 1
DUT deoxyuridine triphosphatase
BLM BLM RecQ like helicase
RMI2 RecQ mediated genome instability 2


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