KEGG 00380 Tryptophan metabolism
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) dme(Fly) cel(Nematoda) mcc(Monkey) cfa(Dog) sce(Budding yeast) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa00380 Tryptophan metabolism 18
hsa00071 Fatty acid degradation 11
hsa00280 Valine, leucine and isoleucine degradation 11
hsa00310 Lysine degradation 10
hsa01212 Fatty acid metabolism 7
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu00380 Tryptophan metabolism 24
mmu00280 Valine, leucine and isoleucine degradation 15
mmu00310 Lysine degradation 13
mmu00071 Fatty acid degradation 11
mmu01212 Fatty acid metabolism 8
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno00380 Tryptophan metabolism 27
rno00280 Valine, leucine and isoleucine degradation 16
rno00310 Lysine degradation 14
rno00071 Fatty acid degradation 12
rno01200 Carbon metabolism 9
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga00380 Tryptophan metabolism 20
gga00280 Valine, leucine and isoleucine degradation 10
gga00310 Lysine degradation 10
gga00071 Fatty acid degradation 8
gga01240 Biosynthesis of cofactors 7
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre00380 Tryptophan metabolism 39
dre00071 Fatty acid degradation 20
dre00280 Valine, leucine and isoleucine degradation 20
dre00310 Lysine degradation 20
dre00330 Arginine and proline metabolism 14
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dme00310 Lysine degradation 10
dme00380 Tryptophan metabolism 10
dme00280 Valine, leucine and isoleucine degradation 7
dme00071 Fatty acid degradation 6
dme01200 Carbon metabolism 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cel00380 Tryptophan metabolism 24
cel00310 Lysine degradation 17
cel00280 Valine, leucine and isoleucine degradation 16
cel00071 Fatty acid degradation 15
cel01212 Fatty acid metabolism 11
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc00380 Tryptophan metabolism 19
mcc00280 Valine, leucine and isoleucine degradation 13
mcc00310 Lysine degradation 10
mcc00071 Fatty acid degradation 9
mcc01240 Biosynthesis of cofactors 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa00380 Tryptophan metabolism 18
cfa00280 Valine, leucine and isoleucine degradation 11
cfa00310 Lysine degradation 10
cfa00071 Fatty acid degradation 9
cfa01240 Biosynthesis of cofactors 7
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
sce00380 Tryptophan metabolism 11
sce01240 Biosynthesis of cofactors 10
sce00310 Lysine degradation 5
sce00620 Pyruvate metabolism 5
sce00010 Glycolysis / Gluconeogenesis 4
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca00380 Tryptophan metabolism 19
fca00310 Lysine degradation 12
fca00280 Valine, leucine and isoleucine degradation 11
fca00071 Fatty acid degradation 10
fca00410 beta-Alanine metabolism 6
Gene list in the network
Symbol Function*
ACADM acyl-CoA dehydrogenase medium chain
ACAT1 acetyl-CoA acetyltransferase 1
ACO1 aconitase 1
ALDH1B1 aldehyde dehydrogenase 1 family member B1
ALDH9A1 aldehyde dehydrogenase 9 family member A1
ATP5F1A ATP synthase F1 subunit alpha
ALDH7A1 aldehyde dehydrogenase 7 family member A1
CAT catalase
CYP1A1 cytochrome P450 family 1 subfamily A member 1
CYP1A2 cytochrome P450 family 1 subfamily A member 2
CYP1B1 cytochrome P450 family 1 subfamily B member 1
DLD dihydrolipoamide dehydrogenase
ECHS1 enoyl-CoA hydratase, short chain 1
FH fumarate hydratase
GCDH glutaryl-CoA dehydrogenase
HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
HADHB hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
HADH hydroxyacyl-CoA dehydrogenase
HSD17B4 hydroxysteroid 17-beta dehydrogenase 4
MAOA monoamine oxidase A
MAOB monoamine oxidase B
ALDH6A1 aldehyde dehydrogenase 6 family member A1
MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
KMO kynurenine 3-monooxygenase
KYNU kynureninase
ECI2 enoyl-CoA delta isomerase 2
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
Symbol Function*
Acadvl acyl-Coenzyme A dehydrogenase, very long chain
Acads acyl-Coenzyme A dehydrogenase, short chain
Aox1 aldehyde oxidase 1
Bckdhb branched chain ketoacid dehydrogenase E1, beta polypeptide
Cat catalase
Cyp2j5 cytochrome P450, family 2, subfamily j, polypeptide 5
Ddc dopa decarboxylase
Dld dihydrolipoamide dehydrogenase
Dpp4 dipeptidylpeptidase 4
Hadh hydroxyacyl-Coenzyme A dehydrogenase
Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4
Maoa monoamine oxidase A
Suclg2 succinate-Coenzyme A ligase, GDP-forming, beta subunit
Aadat aminoadipate aminotransferase
Aass aminoadipate-semialdehyde synthase
Aldh9a1 aldehyde dehydrogenase 9, subfamily A1
Etfdh electron transferring flavoprotein, dehydrogenase
Pccb propionyl Coenzyme A carboxylase, beta polypeptide
Kynu kynureninase
Afmid arylformamidase
Aox3 aldehyde oxidase 3
Bdh1 3-hydroxybutyrate dehydrogenase, type 1
Aldh1b1 aldehyde dehydrogenase 1 family, member B1
Stra6l STRA6-like
Mccc2 methylcrotonoyl-Coenzyme A carboxylase 2 (beta)
Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Upb1 ureidopropionase, beta
Haao 3-hydroxyanthranilate 3,4-dioxygenase
Maob monoamine oxidase B
Acat1 acetyl-Coenzyme A acetyltransferase 1
Aldh7a1 aldehyde dehydrogenase family 7, member A1
Dhtkd1 dehydrogenase E1 and transketolase domain containing 1
Kyat3 kynurenine aminotransferase 3
Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
Aldh8a1 aldehyde dehydrogenase 8 family, member A1
Gcdh glutaryl-Coenzyme A dehydrogenase
Symbol Function*
Acadm acyl-CoA dehydrogenase medium chain
Cat catalase
Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2
Ddc dopa decarboxylase
Ivd isovaleryl-CoA dehydrogenase
Pccb propionyl-CoA carboxylase subunit beta
Cth cystathionine gamma-lyase
Acat1 acetyl-CoA acetyltransferase 1
Gamt guanidinoacetate N-methyltransferase
Acsl1 acyl-CoA synthetase long-chain family member 1
Maob monoamine oxidase B
Maoa monoamine oxidase A
Aadat aminoadipate aminotransferase
Aldh2 aldehyde dehydrogenase 2 family member
Acox1 acyl-CoA oxidase 1
Aox1 aldehyde oxidase 1
Haao 3-hydroxyanthranilate 3,4-dioxygenase
Kmo kynurenine 3-monooxygenase
Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10
Aldh9a1 aldehyde dehydrogenase 9 family, member A1
Decr2 2,4-dienoyl-CoA reductase 2
Aldh3a2 aldehyde dehydrogenase 3 family, member A2
Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4
Aldh6a1 aldehyde dehydrogenase 6 family, member A1
Hadh hydroxyacyl-CoA dehydrogenase
Kynu kynureninase
Decr1 2,4-dienoyl-CoA reductase 1
Echs1 enoyl-CoA hydratase, short chain 1
Sdha succinate dehydrogenase complex flavoprotein subunit A
Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
Acmsd aminocarboxymuconate semialdehyde decarboxylase
Aldh7a1 aldehyde dehydrogenase 7 family, member A1
Aass aminoadipate-semialdehyde synthase
Dld dihydrolipoamide dehydrogenase
Dlst dihydrolipoamide S-succinyltransferase
Iyd iodotyrosine deiodinase
Dhtkd1 dehydrogenase E1 and transketolase domain containing 1
Gcdh glutaryl-CoA dehydrogenase
Aox3 aldehyde oxidase 3
Kyat3 kynurenine aminotransferase 3
Aldh4a1 aldehyde dehydrogenase 4 family, member A1
Gstz1 glutathione S-transferase zeta 1
Afmid arylformamidase
Symbol Function*
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
UQCRC1 ubiquinol-cytochrome c reductase core protein 1
COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor
ALDH3A2 aldehyde dehydrogenase 3 family member A2
DLD dihydrolipoamide dehydrogenase
HGD homogentisate 1,2-dioxygenase
LOC418414 uncharacterized LOC418414
MAOB monoamine oxidase B
MAOA monoamine oxidase A
ACAT1 acetyl-CoA acetyltransferase 1
ECHDC3 enoyl-CoA hydratase domain containing 3
HADH hydroxyacyl-CoA dehydrogenase
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
TDO2 tryptophan 2,3-dioxygenase
DLST dihydrolipoamide S-succinyltransferase
CAT catalase
ACADL acyl-CoA dehydrogenase, long chain
KMO kynurenine 3-monooxygenase
AOX1 aldehyde oxidase 1
AOX2 aldehyde oxidase 2
ACMSD aminocarboxymuconate semialdehyde decarboxylase
KYNU kynureninase
ALDH9A1 aldehyde dehydrogenase 9 family member A1
UQCRC2 ubiquinol-cytochrome c reductase core protein II
AADAT aminoadipate aminotransferase
PCCB propionyl-CoA carboxylase beta subunit
ECHS1 enoyl-CoA hydratase, short chain 1
GCDH glutaryl-CoA dehydrogenase
ECH1 enoyl-CoA hydratase 1
GCAT glycine C-acetyltransferase
Symbol Function*
cat catalase
exorh extra-ocular rhodopsin
aanat2 arylalkylamine N-acetyltransferase 2
gnat1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
aldob aldolase b, fructose-bisphosphate
aldh3a2a aldehyde dehydrogenase 3 family, member A2a
tdo2b tryptophan 2,3-dioxygenase b
aldh7a1 aldehyde dehydrogenase 7 family, member A1
hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
tph1a tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a
aldh2.2 aldehyde dehydrogenase 2 family member, tandem duplicate 2
kmo kynurenine 3-monooxygenase
dlst dihydrolipoamide S-succinyltransferase
echs1 enoyl CoA hydratase, short chain, 1, mitochondrial
grk7b G protein-coupled receptor kinase 7b
slc13a1 solute carrier family 13 member 1
acad11 acyl-CoA dehydrogenase family, member 11
kyat3.2 kynurenine aminotransferase 3, tandem duplicate 2
aldh2.1 aldehyde dehydrogenase 2 family member, tandem duplicate 1
gcdha glutaryl-CoA dehydrogenase a
fh fumarate hydratase
acadl acyl-CoA dehydrogenase long chain
dldh dihydrolipoamide dehydrogenase
aldh9a1b aldehyde dehydrogenase 9 family, member A1b
adh8b alcohol dehydrogenase 8b
nit2 nitrilase family, member 2
mao monoamine oxidase
mccc2 methylcrotonyl-CoA carboxylase subunit 2
ddc dopa decarboxylase
got2a glutamic-oxaloacetic transaminase 2a, mitochondrial
tph2 tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)
hadh hydroxyacyl-CoA dehydrogenase
acat1 acetyl-CoA acetyltransferase 1
aldh3a2b aldehyde dehydrogenase 3 family, member A2b
park7 parkinson protein 7
haao 3-hydroxyanthranilate 3,4-dioxygenase
aldh16a1 aldehyde dehydrogenase 16 family, member A1
dhtkd1 dehydrogenase E1 and transketolase domain containing 1
afmid arylformamidase
phyh phytanoyl-CoA 2-hydroxylase
hadhaa hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
atp5f1b ATP synthase F1 subunit beta
aoc1 amine oxidase copper containing 1
si:ch211-127i16.2 si:ch211-127i16.2
ces2b carboxylesterase 2b
gstr glutathione S-transferase rho
aox6 aldehyde oxidase 6
zgc:162816 zgc:162816
ido1 indoleamine 2,3-dioxygenase 1
kyat1 kynurenine aminotransferase 1
hadhab hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b
ehhadh enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
aldh9a1a.1 aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
aldh9a1a.2 aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2
tdo2a tryptophan 2,3-dioxygenase a
asmt acetylserotonin O-methyltransferase
kynu kynureninase
wu:fb14d09 wu:fb14d09
Symbol Function*
CG10932 uncharacterized protein
shop shopper
CG9547 uncharacterized protein
muc midline uncoordinated
LKRSDH Lysine ketoglutarate reductase/saccharopine dehydrogenase
Mtpalpha Mitochondrial trifunctional protein alpha subunit
UK114 UK114
CG8080 uncharacterized protein
Etf-QO Electron transfer flavoprotein-ubiquinone oxidoreductase
Echs1 Enoyl-CoA hydratase, short chain 1
SdhA Succinate dehydrogenase, subunit A (flavoprotein)
SCOT Succinyl-CoA:3-ketoacid CoA transferase
CG7430 uncharacterized protein
Aldh7A1 Aldehyde dehydrogenase 7 family member A1
ND-39 NADH dehydrogenase (ubiquinone) 39 kDa subunit
CG5214 uncharacterized protein
Kyat Kynurenine aminotransferase
CG31075 uncharacterized protein
CG1544 uncharacterized protein
CG31548 uncharacterized protein
Symbol Function*
hgo-1 Homogentisate 1,2-dioxygenase
atp-1 ATP synthase subunit alpha, mitochondrial
ech-7 Enoyl-CoA Hydratase
pod-2 Acetyl-CoA carboxylase
Y25C1A.13 Uncharacterized protein
kat-1 Acetyl-CoA acetyltransferase homolog, mitochondrial
B0334.3 Uncharacterized protein
F54D5.7 putative glutaryl-CoA dehydrogenase, mitochondrial
VF13D12L.3 Uncharacterized protein
ctl-2 Peroxisomal catalase 1
ctl-3 Catalase
M01F1.4 Uncharacterized protein
alh-1 Aldedh domain-containing protein
hach-1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
ucr-1 Cytochrome b-c1 complex subunit 1, mitochondrial;Peptidase_M16_C domain-containing protein
bas-1 Biogenic Amine Synthesis related
alh-9 Putative aldehyde dehydrogenase family 7 member A1 homolog
tdo-2 Tryptophan 2,3-dioxygenase
alh-12 Aldedh domain-containing protein
ech-6 putative enoyl-CoA hydratase, mitochondrial
acaa-2 ACetyl-CoA Acyltransferase 2 homolog
ogdh-1 2-oxoglutarate dehydrogenase, mitochondrial;Transket_pyr domain-containing protein
elo-5 Elongation of very long chain fatty acids protein 5
elo-6 Elongation of very long chain fatty acids protein 6
dld-1 Dihydrolipoyl dehydrogenase, mitochondrial
hacd-1 Hydroxy-Acyl-CoA Dehydrogenase
alh-5 Aldehyde dehydrogenase
alh-4 Aldehyde dehydrogenase
dlst-1 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
kmo-1 Kynurenine 3-monooxygenase
ogdh-2 Transket_pyr domain-containing protein;putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial
ech-1.1 Enoyl-CoA Hydratase
Y51A2D.18 MFS domain-containing protein
kynu-1 Kynureninase
alh-10 Aldedh domain-containing protein
B0272.3 putative 3-hydroxyacyl-CoA dehydrogenase B0272.3
tbc-6 Growth hormone-regulated TBC protein 6
C05D11.5 Putative hydroxypyruvate isomerase
alh-11 Aldedh domain-containing protein
ckc-1 Choline Kinase C
T02G5.7 Uncharacterized protein
Symbol Function*
IDO1 indoleamine 2,3-dioxygenase 1
DDC dopa decarboxylase
ALDH9A1 aldehyde dehydrogenase 9 family member A1
HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
HADH hydroxyacyl-CoA dehydrogenase
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
SUCLG2 succinate-CoA ligase GDP-forming subunit beta
UQCRC2 ubiquinol-cytochrome c reductase core protein II
GHR growth hormone receptor
DLD dihydrolipoamide dehydrogenase
AOX1 aldehyde oxidase 1
EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
ALDH7A1 aldehyde dehydrogenase 7 family member A1
AIFM1 apoptosis inducing factor mitochondria associated 1
KYNU kynureninase
KMO kynurenine 3-monooxygenase
ACAT1 acetyl-CoA acetyltransferase 1
MCCC1 methylcrotonyl-CoA carboxylase subunit 1
MAOB monoamine oxidase B
ACMSD aminocarboxymuconate semialdehyde decarboxylase
ACAA2 acetyl-CoA acyltransferase 2
UGT2A3 UDP glucuronosyltransferase family 2 member A3
ALDH2 aldehyde dehydrogenase 2 family member
AOC1 amine oxidase copper containing 1
SAMM50 SAMM50 sorting and assembly machinery component
PCCB propionyl-CoA carboxylase subunit beta
CAT catalase
CYP4A11 cytochrome P450 family 4 subfamily A member 11
ECHS1 enoyl-CoA hydratase, short chain 1
VAT1 vesicle amine transport 1
LOC114680279 uncharacterized LOC114680279
Symbol Function*
MAOA monoamine oxidase A
CAT catalase
DLD dihydrolipoamide dehydrogenase
ACSS3 acyl-CoA synthetase short chain family member 3
IDO1 indoleamine 2,3-dioxygenase 1
GCDH glutaryl-CoA dehydrogenase
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
HADH hydroxyacyl-CoA dehydrogenase
SDHA succinate dehydrogenase complex flavoprotein subunit A
KMO kynurenine 3-monooxygenase
ALDH7A1 aldehyde dehydrogenase 7 family member A1
IDO2 indoleamine 2,3-dioxygenase 2
KYNU kynureninase
NMRK1 nicotinamide riboside kinase 1
IL4I1 interleukin 4 induced 1
EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
ACAT1 acetyl-CoA acetyltransferase 1
ACADM acyl-CoA dehydrogenase medium chain
ACAA2 acetyl-CoA acyltransferase 2
ALDH6A1 aldehyde dehydrogenase 6 family member A1
ALDH2 aldehyde dehydrogenase 2 family member
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
DLST dihydrolipoamide S-succinyltransferase
HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
Symbol Function*
LPD1 dihydrolipoyl dehydrogenase
BNA6 nicotinate-nucleotide diphosphorylase (carboxylating)
BNA5 kynureninase
KGD2 alpha-ketoglutarate dehydrogenase KGD2
BNA7 arylformamidase
FDC1 putative phenylacrylic acid decarboxylase FDC1
BNA4 kynurenine 3-monooxygenase
CTT1 catalase T
BNA1 3-hydroxyanthranilate 3,4-dioxygenase
BNA2 dioxygenase BNA2
NRT1 nicotinamide riboside transporter
ALD4 aldehyde dehydrogenase (NADP(+)) ALD4
MSC1 Msc1p
ALD3 aldehyde dehydrogenase (NAD(+)) ALD3
FUM1 fumarase FUM1
ALD6 aldehyde dehydrogenase (NADP(+)) ALD6
Symbol Function*
ALDH9A1 aldehyde dehydrogenase 9 family member A1
MPND MPN domain containing
AFMID arylformamidase
ALDH16A1 aldehyde dehydrogenase 16 family member A1
KYAT3 kynurenine aminotransferase 3
KYAT1 kynurenine aminotransferase 1
PCCB propionyl-CoA carboxylase subunit beta
DDC dopa decarboxylase
HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
ACAD9 acyl-CoA dehydrogenase family member 9
ALDH7A1 aldehyde dehydrogenase 7 family member A1
GCDH glutaryl-CoA dehydrogenase
HADH hydroxyacyl-CoA dehydrogenase
ACAT1 acetyl-CoA acetyltransferase 1
ECHS1 enoyl-CoA hydratase, short chain 1
IVD isovaleryl-CoA dehydrogenase
AADAT aminoadipate aminotransferase
HSD17B4 hydroxysteroid 17-beta dehydrogenase 4
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
NIT2 nitrilase family member 2
CAT catalase
ACADVL acyl-CoA dehydrogenase very long chain
RBKS ribokinase
DLST dihydrolipoamide S-succinyltransferase
ACO1 aconitase 1
KYNU kynureninase
ALDH3A2 aldehyde dehydrogenase 3 family member A2
LOC101098145 dehydrogenase/reductase SDR family member 4
HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
LOC109502579 uncharacterized LOC109502579


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