KEGG 00260 Glycine, serine and threonine metabolism
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) dme(Fly) cel(Nematoda) mcc(Monkey) cfa(Dog) sce(Budding yeast) spo(Fission yeast) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa00260 Glycine, serine and threonine metabolism 21
hsa01200 Carbon metabolism 9
hsa00270 Cysteine and methionine metabolism 8
hsa01230 Biosynthesis of amino acids 8
hsa00330 Arginine and proline metabolism 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu00260 Glycine, serine and threonine metabolism 24
mmu01200 Carbon metabolism 13
mmu01230 Biosynthesis of amino acids 13
mmu00270 Cysteine and methionine metabolism 8
mmu00630 Glyoxylate and dicarboxylate metabolism 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno00260 Glycine, serine and threonine metabolism 26
rno01200 Carbon metabolism 11
rno00270 Cysteine and methionine metabolism 10
rno01230 Biosynthesis of amino acids 10
rno00630 Glyoxylate and dicarboxylate metabolism 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga00260 Glycine, serine and threonine metabolism 21
gga01230 Biosynthesis of amino acids 8
gga00330 Arginine and proline metabolism 7
gga01200 Carbon metabolism 7
gga00270 Cysteine and methionine metabolism 7
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre00260 Glycine, serine and threonine metabolism 33
dre01200 Carbon metabolism 17
dre01230 Biosynthesis of amino acids 17
dre00270 Cysteine and methionine metabolism 10
dre00630 Glyoxylate and dicarboxylate metabolism 9
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dme00260 Glycine, serine and threonine metabolism 20
dme01200 Carbon metabolism 10
dme01230 Biosynthesis of amino acids 9
dme00270 Cysteine and methionine metabolism 7
dme00630 Glyoxylate and dicarboxylate metabolism 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cel00260 Glycine, serine and threonine metabolism 19
cel01200 Carbon metabolism 11
cel01230 Biosynthesis of amino acids 10
cel00270 Cysteine and methionine metabolism 5
cel00630 Glyoxylate and dicarboxylate metabolism 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc00260 Glycine, serine and threonine metabolism 17
mcc01230 Biosynthesis of amino acids 11
mcc01200 Carbon metabolism 9
mcc00270 Cysteine and methionine metabolism 8
mcc00010 Glycolysis / Gluconeogenesis 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa00260 Glycine, serine and threonine metabolism 14
cfa01200 Carbon metabolism 7
cfa00270 Cysteine and methionine metabolism 6
cfa01230 Biosynthesis of amino acids 5
cfa00630 Glyoxylate and dicarboxylate metabolism 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
sce01230 Biosynthesis of amino acids 21
sce00260 Glycine, serine and threonine metabolism 20
sce01200 Carbon metabolism 12
sce00270 Cysteine and methionine metabolism 8
sce00680 Methane metabolism 7
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
spo00260 Glycine, serine and threonine metabolism 22
spo01230 Biosynthesis of amino acids 15
spo00270 Cysteine and methionine metabolism 9
spo01200 Carbon metabolism 7
spo01240 Biosynthesis of cofactors 7
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca00260 Glycine, serine and threonine metabolism 15
fca01230 Biosynthesis of amino acids 7
fca01200 Carbon metabolism 6
fca00270 Cysteine and methionine metabolism 6
fca00330 Arginine and proline metabolism 4
Gene list in the network
Symbol Function*
ACADM acyl-CoA dehydrogenase medium chain
AFM afamin
AMT aminomethyltransferase
AOC2 amine oxidase copper containing 2
BHMT betaine--homocysteine S-methyltransferase
CTH cystathionine gamma-lyase
DAO D-amino acid oxidase
DLD dihydrolipoamide dehydrogenase
G6PC1 glucose-6-phosphatase catalytic subunit 1
GAMT guanidinoacetate N-methyltransferase
GATM glycine amidinotransferase
MAOA monoamine oxidase A
MAOB monoamine oxidase B
PLG plasminogen
PSPH phosphoserine phosphatase
SHMT2 serine hydroxymethyltransferase 2
AOC3 amine oxidase copper containing 3
SDS serine dehydratase
GCAT glycine C-acetyltransferase
BHMT2 betaine--homocysteine S-methyltransferase 2
PHGDH phosphoglycerate dehydrogenase
DMGDH dimethylglycine dehydrogenase
PSAT1 phosphoserine aminotransferase 1
PIPOX pipecolic acid and sarcosine oxidase
AGXT2 alanine--glyoxylate aminotransferase 2
GPT2 glutamic--pyruvic transaminase 2
SDSL serine dehydratase like
NUDT8 nudix hydrolase 8
LOC105378936 uncharacterized LOC105378936
Symbol Function*
Agxt alanine-glyoxylate aminotransferase
Alas2 aminolevulinic acid synthase 2, erythroid
Bhmt betaine-homocysteine methyltransferase
Bpgm 2,3-bisphosphoglycerate mutase
Cbs cystathionine beta-synthase
Gamt guanidinoacetate methyltransferase
Gnmt glycine N-methyltransferase
Hpd 4-hydroxyphenylpyruvic acid dioxygenase
Maoa monoamine oxidase A
Pgam1 phosphoglycerate mutase 1
Snca synuclein, alpha
Tpi1 triosephosphate isomerase 1
Aldh18a1 aldehyde dehydrogenase 18 family, member A1
Bhmt2 betaine-homocysteine methyltransferase 2
Gcsh glycine cleavage system protein H (aminomethyl carrier)
Tha1 threonine aldolase 1
Dmgdh dimethylglycine dehydrogenase precursor
Grhpr glyoxylate reductase/hydroxypyruvate reductase
Psph phosphoserine phosphatase
Gldc glycine decarboxylase
Psat1 phosphoserine aminotransferase 1
Aldh1l1 aldehyde dehydrogenase 1 family, member L1
Cth cystathionase (cystathionine gamma-lyase)
Shmt2 serine hydroxymethyltransferase 2 (mitochondrial)
Gpt2 glutamic pyruvate transaminase (alanine aminotransferase) 2
Maob monoamine oxidase B
Qdpr quinoid dihydropteridine reductase
Sardh sarcosine dehydrogenase
Gls2 glutaminase 2 (liver, mitochondrial)
Sds serine dehydratase
Phgdh 3-phosphoglycerate dehydrogenase
Sdsl serine dehydratase-like
Amt aminomethyltransferase
Symbol Function*
Agt angiotensinogen
Cbs cystathionine beta synthase
Hbb hemoglobin subunit beta
Cth cystathionine gamma-lyase
Sds serine dehydratase
Gamt guanidinoacetate N-methyltransferase
Tst thiosulfate sulfurtransferase
Asns asparagine synthetase (glutamine-hydrolyzing)
Alas2 5'-aminolevulinate synthase 2
Maob monoamine oxidase B
Maoa monoamine oxidase A
Slc37a4 solute carrier family 37 member 4
Phgdh phosphoglycerate dehydrogenase
Bhmt betaine-homocysteine S-methyltransferase
Agxt2 alanine-glyoxylate aminotransferase 2
Sardh sarcosine dehydrogenase
Gcsh glycine cleavage system protein H
Dmgdh dimethylglycine dehydrogenase
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4
Chdh choline dehydrogenase
Aldh7a1 aldehyde dehydrogenase 7 family, member A1
Psat1 phosphoserine aminotransferase 1
Bpgm bisphosphoglycerate mutase
Mkrn1 makorin ring finger protein 1
Shmt2 serine hydroxymethyltransferase 2
Pipox pipecolic acid and sarcosine oxidase
Psph phosphoserine phosphatase
Amt aminomethyltransferase
Yars1 tyrosyl-tRNA synthetase 1
Sdsl serine dehydratase-like
Dhtkd1 dehydrogenase E1 and transketolase domain containing 1
Tkfc triokinase and FMN cyclase
Suclg2 succinate-CoA ligase GDP-forming subunit beta
Bhmt2 betaine-homocysteine S-methyltransferase 2
Gcat glycine C-acetyltransferase
Acad8 acyl-CoA dehydrogenase family, member 8
Grhpr glyoxylate and hydroxypyruvate reductase
Glyctk glycerate kinase
Etnppl ethanolamine-phosphate phospho-lyase
LOC688286 similar to threonine aldolase 1
Symbol Function*
ATP5F1AZ ATP synthase F1 subunit alpha Z chromosome
GATM glycine amidinotransferase
AMT aminomethyltransferase
GPT2 glutamic--pyruvic transaminase 2
GCSH glycine cleavage system protein H
DMGDH dimethylglycine dehydrogenase
BHMT2 betaine--homocysteine S-methyltransferase 2
PSPH phosphoserine phosphatase
CBSL cystathionine-beta-synthase like
MAOB monoamine oxidase B
MAOA monoamine oxidase A
FOXRED1 FAD dependent oxidoreductase domain containing 1
MAT1A methionine adenosyltransferase 1A
ALDH18A1 aldehyde dehydrogenase 18 family member A1
PHGDH phosphoglycerate dehydrogenase
CTH cystathionine gamma-lyase
OAT ornithine aminotransferase
GRHPR glyoxylate and hydroxypyruvate reductase
ALDH7A1 aldehyde dehydrogenase 7 family member A1
ACSM5 acyl-CoA synthetase medium-chain family member 5
PSAT1 phosphoserine aminotransferase 1
AVDL avidin-like
AGXT2 alanine--glyoxylate aminotransferase 2
ALAS1 5'-aminolevulinate synthase 1
MPC2 mitochondrial pyruvate carrier 2
CPN1 carboxypeptidase N subunit 1
GNMT glycine N-methyltransferase
AGXT alanine-glyoxylate aminotransferase
GAMT guanidinoacetate N-methyltransferase
PIPOX pipecolic acid and sarcosine oxidase
HSDL2 hydroxysteroid dehydrogenase like 2
TCEA3 transcription elongation factor A3
GCAT glycine C-acetyltransferase
LOC101751878 solute carrier family 2, facilitated glucose transporter member 11-like
Symbol Function*
pcxb pyruvate carboxylase b
agxtb alanine--glyoxylate and serine--pyruvate aminotransferase b
fabp10a fatty acid binding protein 10a, liver basic
gpia glucose-6-phosphate isomerase a
gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase)
cbsb cystathionine beta-synthase b
gapdh glyceraldehyde-3-phosphate dehydrogenase
gldc glycine dehydrogenase (decarboxylating)
aldob aldolase b, fructose-bisphosphate
phgdh phosphoglycerate dehydrogenase
cth cystathionase (cystathionine gamma-lyase)
bhmt betaine-homocysteine methyltransferase
arg2 arginase 2
pgam1a phosphoglycerate mutase 1a
pgam1b phosphoglycerate mutase 1b
psat1 phosphoserine aminotransferase 1
aldh7a1 aldehyde dehydrogenase 7 family, member A1
slc1a4 solute carrier family 1 member 4
mtr 5-methyltetrahydrofolate-homocysteine methyltransferase
ahcy adenosylhomocysteinase
shmt1 serine hydroxymethyltransferase 1 (soluble)
sardh sarcosine dehydrogenase
gcat glycine C-acetyltransferase
nit2 nitrilase family, member 2
grhprb glyoxylate reductase/hydroxypyruvate reductase b
gnmt glycine N-methyltransferase
mao monoamine oxidase
tdh L-threonine dehydrogenase
tha1 threonine aldolase 1
agxta alanine--glyoxylate and serine--pyruvate aminotransferase a
akr7a3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
gcshb glycine cleavage system protein H (aminomethyl carrier), b
cthl cystathionase (cystathionine gamma-lyase), like
slc27a2a solute carrier family 27 member 2a
amt aminomethyltransferase
aldh16a1 aldehyde dehydrogenase 16 family, member A1
dhtkd1 dehydrogenase E1 and transketolase domain containing 1
cbsa cystathionine beta-synthase a
ttc38 tetratricopeptide repeat domain 38
uroc1 urocanate hydratase 1
acmsd aminocarboxymuconate semialdehyde decarboxylase
si:ch211-127i16.2 si:ch211-127i16.2
pipox pipecolic acid oxidase
ces2b carboxylesterase 2b
ugt5c3 UDP glucuronosyltransferase 5 family, polypeptide C3
glyctk glycerate kinase
pgam2 phosphoglycerate mutase 2 (muscle)
dao.1 D-amino-acid oxidase, tandem duplicate 1
agxt2 alanine--glyoxylate aminotransferase 2
thnsl2 threonine synthase-like 2
acsf2 acyl-CoA synthetase family member 2
gamt guanidinoacetate N-methyltransferase
hal histidine ammonia-lyase
dmgdh dimethylglycine dehydrogenase
shmt2 serine hydroxymethyltransferase 2 (mitochondrial)
aldh1l1 aldehyde dehydrogenase 1 family, member L1
Symbol Function*
Shmt Serine hydroxymethyl transferase
Spat Serine pyruvate aminotransferase
Paics PAICS bifunctional enzyme
CG1673 uncharacterized protein
Ahcy Adenosylhomocysteinase
Cbs Cystathionine beta-synthase
CG9886 uncharacterized protein
Pfas Phosphoribosylformylglycinamidine synthase
CG9547 uncharacterized protein
Galt Galactose-1-phosphate uridylyltransferase
CG11236 uncharacterized protein
CG6415 uncharacterized protein
CG6287 uncharacterized protein
hll heimdall
Cyt-b5-r Cytochrome b5-related
CG10621 uncharacterized protein
Sardh Sarcosine dehydrogenase
Eip55E Ecdysone-induced protein 55E
Alas Aminolevulinate synthase
Prat2 Phosphoribosylamidotransferase 2
aay astray
CG10361 uncharacterized protein
CG7430 uncharacterized protein
Aldh7A1 Aldehyde dehydrogenase 7 family member A1
Oat Ornithine aminotransferase precursor
CG5955 uncharacterized protein
CG11425 uncharacterized protein
Sodh-1 Sorbitol dehydrogenase 1
CG18473 uncharacterized protein
Srr Serine racemase
CG3999 uncharacterized protein
Gnmt Glycine N-methyltransferase
UQCR-C1 Ubiquinol-cytochrome c reductase core protein 1
AdSL Adenylosuccinate Lyase
CG10184 uncharacterized protein
CG11089 uncharacterized protein
CG11899 uncharacterized protein
Symbol Function*
Y37E3.17 Uncharacterized protein
T19B4.3 Adenine phosphoribosyltransferase
T09B4.8 Uncharacterized protein
ipgm-1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
gcsh-2 Glycine cleavage system H protein
F26H9.5 putative phosphoserine aminotransferase
hprt-1 Hypoxanthine phosphoribosyltransferase
gldc-1 Glycine cleavage system P protein
cth-2 Putative cystathionine gamma-lyase 2
K01C8.1 Threonine ammonia-lyase
pah-1 Phenylalanine-4-hydroxylase
enol-1 Enolase
C31C9.2 Uncharacterized protein
alh-9 Putative aldehyde dehydrogenase family 7 member A1 homolog
R102.4 Beta_elim_lyase domain-containing protein
T25B9.1 Aminotran_1_2 domain-containing protein
Y62E10A.13 O-phosphoserine phosphohydrolase
dld-1 Dihydrolipoyl dehydrogenase, mitochondrial
nuo-5 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
F08F3.4 Epimerase domain-containing protein
gcst-1 Aminomethyltransferase
Y51A2D.18 MFS domain-containing protein
dpyd-1 Dihydropyrimidine dehydrogenase [NADP(+)]
argn-1 ARGiNase Homolog
cbs-1 PALP domain-containing protein
gcsh-1 Glycine cleavage system H protein
serr-1 L-serine ammonia-lyase
Symbol Function*
GAPDH glyceraldehyde-3-phosphate dehydrogenase
CYP2C8 cytochrome P450 family 2 subfamily C member 8
CHDH choline dehydrogenase
CTH cystathionine gamma-lyase
LOC696959 phosphoglycerate mutase 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
AGXT2 alanine--glyoxylate aminotransferase 2
SLC1A4 solute carrier family 1 member 4
AGXT alanine--glyoxylate and serine--pyruvate aminotransferase
PGAM1 phosphoglycerate mutase 1
PSAT1 phosphoserine aminotransferase 1
LOC708053 membrane primary amine oxidase
DMGDH dimethylglycine dehydrogenase
WASF3 WASP family member 3
LOC711820 amine oxidase copper containing 3
PHGDH phosphoglycerate dehydrogenase
BHMT2 betaine--homocysteine S-methyltransferase 2
BHMT betaine--homocysteine S-methyltransferase
SHMT2 serine hydroxymethyltransferase 2
SDSL serine dehydratase like
PYCR1 pyrroline-5-carboxylate reductase 1
GLDC glycine decarboxylase
PRAP1 proline rich acidic protein 1
CBS cystathionine beta-synthase
AOC2 amine oxidase copper containing 2
Symbol Function*
CYP2E1 cytochrome P450 family 2 subfamily E member 1
ALAD aminolevulinate dehydratase
PSAT1 phosphoserine aminotransferase 1
KNG1 kininogen 1
BHMT betaine--homocysteine S-methyltransferase
CTH cystathionine gamma-lyase
PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial
GCAT glycine C-acetyltransferase
ALDH7A1 aldehyde dehydrogenase 7 family member A1
GLDC glycine decarboxylase
GLYCTK glycerate kinase
SDSL serine dehydratase like
BHMT2 betaine--homocysteine S-methyltransferase 2
DMGDH dimethylglycine dehydrogenase
PSPH phosphoserine phosphatase
SHMT2 serine hydroxymethyltransferase 2
GRHPR glyoxylate and hydroxypyruvate reductase
AGXT2 alanine--glyoxylate aminotransferase 2
AGXT alanine--glyoxylate and serine--pyruvate aminotransferase
Symbol Function*
ILV6 acetolactate synthase regulatory subunit
THR4 threonine synthase THR4
SHM2 glycine hydroxymethyltransferase SHM2
SAM1 methionine adenosyltransferase SAM1
CYS3 cystathionine gamma-lyase CYS3
GCV3 glycine decarboxylase subunit H
GPM2 phosphoglycerate mutase family protein GPM2
GCV1 glycine decarboxylase subunit T
HOM2 aspartate-semialdehyde dehydrogenase
HEM1 5-aminolevulinate synthase
ARO8 bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase
TPN1 Tpn1p
TRP5 tryptophan synthase TRP5
CYS4 cystathionine beta-synthase CYS4
SER2 phosphoserine phosphatase
BNA3 kynurenine--oxoglutarate transaminase
TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
GPM1 phosphoglycerate mutase GPM1
MTD1 methylenetetrahydrofolate dehydrogenase (NAD(+))
MET22 3'(2'),5'-bisphosphate nucleotidase
GPM3 phosphoglycerate mutase family protein GPM3
DED1 DEAD-box ATP-dependent RNA helicase DED1
SER33 phosphoglycerate dehydrogenase SER33
ILV2 acetolactate synthase catalytic subunit
GCV2 glycine decarboxylase subunit P
ADE4 amidophosphoribosyltransferase
THR1 homoserine kinase
GLY1 threonine aldolase GLY1
HOM3 aspartate kinase
SER3 phosphoglycerate dehydrogenase SER3
ILV1 threonine ammonia-lyase ILV1
Symbol Function*
SPCC320.14 putative threo-3-hydroxyaspartate ammonia-lyase
pps1 phosphatidylserine synthase Pps1
SPCC1450.07c putative D-amino acid oxidase
SPCC1827.06c putative aspartate semialdehyde dehydrogenase
SPCC364.07 putative D-3 phosphoglycerate dehydrogenase
ade10 IMP cyclohydrolase/phosphoribosylaminoimidazolecarboxamideformyltransferase
sam1 S-adenosylmethionine synthetase
cho2 phosphatidylethanolamine N-methyltransferase Cho2
SPBC19F5.04 putative aspartate kinase
SPBC4C3.03 putative homoserine kinase
fap1 L-pipecolate oxidase
cho1 putative phosphatidyl-N-methylethanolamine N-methyltransferase
SPBC776.03 putative homoserine dehydrogenase
SPBC839.16 C1-5,6,7,8-tetrahydrofolate (THF) synthase
gcv3 putative glycine decarboxylase complex subunit H
SPAC1F7.09c putative allantoicase
lys3 saccharopine dehydrogenase Lys3
gpd2 glycerol-3-phosphate dehydrogenase Gpd2
SPAP11E10.01 putative ornithine cyclodeaminase family protein
cao1 Cu(2+) amine oxidase Cao1
gly1 putative threonine aldolase Gly1
frs1 putative phenylalanine--tRNA (Phe) ligase beta subunit Frs1
hem1 putative 5-aminolevulinate synthase
trp2 putative tryptophan synthase
shm2 putative serine hydroxymethyltransferase Shm2
SPAC1F12.07 putative phosphoserine aminotransferase
SPAC24C9.12c putative glycine hydroxymethyltransferase
SPAC9E9.06c putative threonine synthase
ade2 adenylosuccinate synthetase Ade2
gcv2 putative glycine cleavage complex subunit P
SPAC1039.07c aminotransferase
SPAC1039.06 putative alanine racemase
gcv1 putative glycine decarboxylase T subunit gcv1
SPAC323.04 putative ATPase
SPAC56E4.03 putative aromatic aminotransferase
SPAC521.03 putative dehydrogenase
SPAC922.03 putative 1-aminocyclopropane-1-carboxylate deaminase
met26 homocysteine methyltransferase Met26
Symbol Function*
GATM glycine amidinotransferase
GRHPR glyoxylate and hydroxypyruvate reductase
GLYCTK glycerate kinase
PSPH phosphoserine phosphatase
GBA3 glucosylceramidase beta 3
BHMT2 betaine--homocysteine S-methyltransferase 2
BHMT betaine--homocysteine S-methyltransferase
SHMT1 serine hydroxymethyltransferase 1
ALDH7A1 aldehyde dehydrogenase 7 family member A1
DAO D-amino acid oxidase
QDPR quinoid dihydropteridine reductase
GPT2 glutamic--pyruvic transaminase 2
PHGDH phosphoglycerate dehydrogenase
DMGDH dimethylglycine dehydrogenase
CHDH choline dehydrogenase
SLC1A5 solute carrier family 1 member 5
MAOB monoamine oxidase B
CBS cystathionine beta-synthase
KLF15 Kruppel like factor 15
PSAT1 phosphoserine aminotransferase 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
AGXT2 alanine--glyoxylate aminotransferase 2


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