KEGG 00630 Glyoxylate and dicarboxylate metabolism

30  hsa genes in this database.
32  mmu genes in this database.
31  rno genes in this database.
31  gga genes in this database.
37  dre genes in this database.
33  dme genes in this database.
36  cel genes in this database.
32  mcc genes in this database.
33  cfa genes in this database.
29  sce genes in this database.
18  spo genes in this database.
31  fca genes in this database.

List of genes in hsa


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
38 , M ACAT1 acetyl-CoA acetyltransferase 1
39 , M ACAT2 acetyl-CoA acetyltransferase 2
48 , Y ACO1 aconitase 1
50 , M ACO2 aconitase 2
189 , Y AGXT alanine--glyoxylate and serine--pyruvate aminotransferase
275 , M AMT aminomethyltransferase
847 , Y CAT catalase
1431 , M CS citrate synthase
1738 , M DLD dihydrolipoamide dehydrogenase
2653 , M GCSH glycine cleavage system protein H
2731 , M GLDC glycine decarboxylase
2752 , Y GLUL glutamate-ammonia ligase
4190 , Y MDH1 malate dehydrogenase 1
4191 , M MDH2 malate dehydrogenase 2
4594 , Y MMUT methylmalonyl-CoA mutase
5095 , M PCCA propionyl-CoA carboxylase subunit alpha
5096 , M PCCB propionyl-CoA carboxylase subunit beta
6470 , Y SHMT1 serine hydroxymethyltransferase 1
6472 , M SHMT2 serine hydroxymethyltransferase 2
9380 , M GRHPR glyoxylate and hydroxypyruvate reductase
51179 , K HAO2 hydroxyacid oxidase 2
54363 , Y HAO1 hydroxyacid oxidase 1
55902 , Y ACSS2 acyl-CoA synthetase short chain family member 2
81888 , M HYI hydroxypyruvate isomerase (putative)
84532 , M ACSS1 acyl-CoA synthetase short chain family member 1
84693 , M MCEE methylmalonyl-CoA epimerase
112817 , S HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
125061 , Y AFMID arylformamidase
132158 , M GLYCTK glycerate kinase
283871 , S PGP phosphoglycolate phosphatase


List of genes in mmu


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
11428 , Y Aco1 aconitase 1
11429 , M Aco2 aconitase 2, mitochondrial
11611 , Y Agxt alanine-glyoxylate aminotransferase
12359 , Y Cat catalase
12974 , M Cs citrate synthase
13382 , M Dld dihydrolipoamide dehydrogenase
14645 , Y Glul glutamate-ammonia ligase (glutamine synthetase)
15112 , Y Hao1 hydroxyacid oxidase 1, liver
17448 , M Mdh2 malate dehydrogenase 2, NAD (mitochondrial)
17449 , Y Mdh1 malate dehydrogenase 1, NAD (soluble)
17850 , M Mmut methylmalonyl-Coenzyme A mutase
20425 , Y Shmt1 serine hydroxymethyltransferase 1 (soluble)
56185 , Y Hao2 hydroxyacid oxidase 2
60525 , Y Acss2 acyl-CoA synthetase short-chain family member 2
66904 , M Pccb propionyl Coenzyme A carboxylase, beta polypeptide
67078 , Y Pgp phosphoglycolate phosphatase
67432 , P Hoga1 4-hydroxy-2-oxoglutarate aldolase 1
68133 , M Gcsh glycine cleavage system protein H (aminomethyl carrier)
68180 , M Hyi hydroxypyruvate isomerase (putative)
68738 , M Acss1 acyl-CoA synthetase short-chain family member 1
71562 , P Afmid arylformamidase
71832 , M Csl citrate synthase like
73724 , M Mcee methylmalonyl CoA epimerase
76238 , M Grhpr glyoxylate reductase/hydroxypyruvate reductase
104174 , M Gldc glycine decarboxylase
108037 , M Shmt2 serine hydroxymethyltransferase 2 (mitochondrial)
110446 , M Acat1 acetyl-Coenzyme A acetyltransferase 1
110460 , X Acat2 acetyl-Coenzyme A acetyltransferase 2
110821 , M Pcca propionyl-Coenzyme A carboxylase, alpha polypeptide
224530 , X Acat3 acetyl-Coenzyme A acetyltransferase 3
235582 , M Glyctk glycerate kinase
434437 , M Amt aminomethyltransferase


List of genes in rno


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
24248 , Y Cat catalase
24551 , Y Mdh1 malate dehydrogenase 1
24624 , M Pccb propionyl-CoA carboxylase subunit beta
24792 , M Agxt alanine--glyoxylate and serine--pyruvate aminotransferase
24957 , Y Glul glutamate-ammonia ligase
25014 , M Acat1 acetyl-CoA acetyltransferase 1
50655 , Y Aco1 aconitase 1
79250 , M Aco2 aconitase 2
81829 , M Mdh2 malate dehydrogenase 2
84029 , Y Hao2 hydroxyacid oxidase 2
170587 , M Cs citrate synthase
171133 , M Gcsh glycine cleavage system protein H
287115 , Y Pgp phosphoglycolate phosphatase
287379 , K Shmt1 serine hydroxymethyltransferase 1
293829 , M Mcee methylmalonyl CoA epimerase
293949 , M Hoga1 4-hydroxy-2-oxoglutarate aldolase 1
296259 , M Acss1 acyl-CoA synthetase short-chain family member 1
298942 , M Dld dihydrolipoamide dehydrogenase
299857 , M Shmt2 serine hydroxymethyltransferase 2
306586 , M Amt aminomethyltransferase
308100 , X Acat2 acetyl-CoA acetyltransferase 2
309312 , M Gldc glycine decarboxylase
311446 , Y Hao1 hydroxyacid oxidase 1
311569 , Y Acss2 acyl-CoA synthetase short-chain family member 2
365096 , X Acat2l1 acetyl-CoA acetyltransferase 2-like 1
500536 , M Hyi hydroxypyruvate isomerase
680021 , M Grhpr glyoxylate and hydroxypyruvate reductase
684314 , M Glyctk glycerate kinase
687008 , M Pcca propionyl-CoA carboxylase subunit alpha
688283 , Y_N Afmid arylformamidase
688517 , Y Mmut methylmalonyl-CoA mutase


List of genes in gga


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
373916 , Y ACO1 aconitase 1, soluble
374009 , M ACO2 aconitase 2
374222 , N GLDC glycine decarboxylase
395566 , M AMT aminomethyltransferase
396489 , Y GLUL glutamate-ammonia ligase
415385 , M MCEE methylmalonyl-CoA epimerase
415803 , M GCSH glycine cleavage system protein H
416520 , N SHMT1 serine hydroxymethyltransferase 1
416559 , M PGP phosphoglycolate phosphatase
416714 , Y ACSS1A acyl-CoA synthetase short-chain family member 1A
416728 , Y HAO1 hydroxyacid oxidase 1
417253 , S GSL glutamine synthetase-like
417517 , M MDH2 malate dehydrogenase 2
417699 , M DLD dihydrolipoamide dehydrogenase
418311 , Y HAO2 hydroxyacid oxidase 2
418774 , M PCCA propionyl-CoA carboxylase alpha subunit
418968 , M ACAT1 acetyl-CoA acetyltransferase 1
419158 , Y ACSS2 acyl-CoA synthetase short-chain family member 2
421281 , M MDH1 malate dehydrogenase 1
421587 , X ACAT2 acetyl-CoA acetyltransferase 2
422049 , M MUT methylmalonyl-CoA mutase
423347 , M ACSS1B acyl-CoA synthetase short-chain family member 1B
423600 , Y CAT catalase
424567 , Y HYI hydroxypyruvate isomerase (putative)
426806 , M GRHPR glyoxylate and hydroxypyruvate reductase
427577 , M GLYCTK glycerate kinase
768706 , M PCCB propionyl-CoA carboxylase beta subunit
769005 , Y AFMID arylformamidase
770036 , M HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
770344 , M AGXT alanine-glyoxylate aminotransferase
100858903 , M CS citrate synthase


List of genes in dre


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
30068 , Y cat catalase
30643 , X acat2 acetyl-CoA acetyltransferase 2
79378 , M agxtb alanine--glyoxylate and serine--pyruvate aminotransferase b
321621 , M gldc glycine dehydrogenase (decarboxylating)
322339 , M cs citrate synthase
322670 , M aco2 aconitase 2, mitochondrial
335715 , M mdh1ab malate dehydrogenase 1Ab, NAD (soluble)
336473 , Y glulb glutamate-ammonia ligase (glutamine synthase) b
393305 , Y_N hyi hydroxypyruvate isomerase
393455 , Y hao2 hydroxyacid oxidase 2 (long chain)
394021 , Y shmt1 serine hydroxymethyltransferase 1 (soluble)
399479 , M dldh dihydrolipoamide dehydrogenase
399662 , S mdh1aa malate dehydrogenase 1Aa, NAD (soluble)
402827 , Y hao1 hydroxyacid oxidase (glycolate oxidase) 1
402985 , M grhprb glyoxylate reductase/hydroxypyruvate reductase b
405806 , M hoga1 4-hydroxy-2-oxoglutarate aldolase 1
405861 , M pccb propionyl-CoA carboxylase subunit beta
406405 , M mdh2 malate dehydrogenase 2, NAD (mitochondrial)
436603 , Y agxta alanine--glyoxylate and serine--pyruvate aminotransferase a
436852 , S gcshb glycine cleavage system protein H (aminomethyl carrier), b
436914 , Y acss2 acyl-CoA synthetase short chain family member 2
437019 , M pcca propionyl-CoA carboxylase subunit alpha
445290 , M acat1 acetyl-CoA acetyltransferase 1
450000 , M amt aminomethyltransferase
497183 , M grhpra glyoxylate reductase/hydroxypyruvate reductase a
541329 , S gcsha glycine cleavage system protein H (aminomethyl carrier), a
541435 , M acss1 acyl-CoA synthetase short chain family member 1
550372 , Y afmid arylformamidase
553804 , M mcee methylmalonyl CoA epimerase
560020 , Y acss2l acyl-CoA synthetase short chain family member 2 like
566165 , Y glulc glutamate-ammonia ligase (glutamine synthase) c
568448 , Y aco1 aconitase 1, soluble
569581 , M mmut methylmalonyl CoA mutase
570678 , M glyctk glycerate kinase
792824 , M pgp phosphoglycolate phosphatase
100000775 , Y glula glutamate-ammonia ligase (glutamine synthase) a
100144628 , M shmt2 serine hydroxymethyltransferase 2 (mitochondrial)


List of genes in dme


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
31524 , Y Shmt Serine hydroxymethyl transferase
31579 , M kdn knockdown
31587 , Y Spat Serine pyruvate aminotransferase
31695 , M CG10932 uncharacterized protein
31960 , Y Gip GIP-like
32087 , Y Gs2 Glutamine synthetase 2
33172 , M Gs1 Glutamine synthetase 1
33431 , M CG9886 uncharacterized protein
33907 , Y KFase Kynurenine formamidase
34198 , Y CG9314 uncharacterized protein
34414 , Y Mdh1 Malate dehydrogenase 1
34474 , M CG6415 uncharacterized protein
37541 , M CG11291 uncharacterized protein
38147 , X CG9149 uncharacterized protein
38358 , Y CG32487 uncharacterized protein
39469 , M CG10748 uncharacterized protein
39470 , Y CG10749 uncharacterized protein
39985 , Y_N CG5577 uncharacterized protein
39986 , M CG5567 uncharacterized protein
39988 , M CG7430 uncharacterized protein
40048 , Y Cat Catalase
40348 , Y AcCoAS Acetyl Coenzyme A synthase
40349 , M ppl pumpless
40708 , M CG1236 uncharacterized protein
41253 , M CG3999 uncharacterized protein
41269 , Y Irp-1B Iron regulatory protein 1B
41326 , M mAcon2 Mitochondrial aconitase 2
41468 , Y CG14740 uncharacterized protein
42185 , Y Mdh2 Malate dehydrogenase 2
42689 , Y Irp-1A Iron regulatory protein 1A
44149 , M mAcon1 Mitochondrial aconitase 1
326220 , M CG32488 uncharacterized protein
3771779 , Y CG18003 uncharacterized protein


List of genes in cel


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
172486 , M gcsh-2 Glycine cleavage system H protein
172514 , M mce-1 VOC domain-containing protein
174012 , Y gldc-1 Glycine cleavage system P protein
174161 , M kat-1 Acetyl-CoA acetyltransferase homolog, mitochondrial
174414 , M agxt-1 Serine--pyruvate aminotransferase
175085 , Y ctl-2 Peroxisomal catalase 1
175086 , Y ctl-3 Catalase
175500 , Y acs-19 Acetyl-coenzyme A synthetase
175503 , M mmcm-1 putative methylmalonyl-CoA mutase, mitochondrial
175915 , Y mel-32 Serine hydroxymethyltransferase
175936 , M mdh-2 putative malate dehydrogenase, mitochondrial
176121 , Y aco-2 putative aconitate hydratase, mitochondrial
176407 , Y gln-2 putative glutamine synthetase
176437 , M cts-1 putative citrate synthase, mitochondrial
177499 , Y afmd-1 Abhydrolase_3 domain-containing protein
177808 , N gln-6 Glutamine synthetase
178387 , M dld-1 Dihydrolipoyl dehydrogenase, mitochondrial
178452 , Y gln-3 Gln-synt_C domain-containing protein;Glutamine synthetase
178505 , N gln-5 Glutamine synthetase
178583 , Y_N icl-1 Malate synthase
178960 , M gcst-1 Aminomethyltransferase
178963 , N pgph-1 PhosphoGlycolate Phosphatase Homolog
178964 , N pgph-3 PhosphoGlycolate Phosphatase Homolog
178965 , N pgph-2 PhosphoGlycolate Phosphatase Homolog
179041 , M mdh-1 Malate dehydrogenase
179241 , Y F41E6.5 FMN hydroxy acid dehydrogenase domain-containing protein
180596 , Y pccb-1 Propionyl Coenzyme A Carboxylase Beta subunit
180875 , M gln-1 Gln-synt_C domain-containing protein
181026 , M pcca-1 Propionyl-CoA carboxylase alpha chain, mitochondrial
181324 , Y aco-1 putative cytoplasmic aconitate hydratase
182258 , M C05D11.5 Putative hydroxypyruvate isomerase
183469 , Y C45E5.1 Uncharacterized protein
183902 , M gcsh-1 Glycine cleavage system H protein
259738 , Y ctl-1 Catalase-2
266887 , M C13B9.2 Uncharacterized protein
3565206 , Y T02G5.7 Uncharacterized protein


List of genes in mcc


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
694185 , M GRHPR glyoxylate and hydroxypyruvate reductase
694703 , Y MDH1 malate dehydrogenase 1
695591 , S PGP phosphoglycolate phosphatase
697521 , M GLYCTK glycerate kinase
698520 , M LOC698520 glycine cleavage system H protein, mitochondrial
699844 , M PCCA propionyl-CoA carboxylase subunit alpha
699941 , M AGXT alanine--glyoxylate and serine--pyruvate aminotransferase
700494 , M DLD dihydrolipoamide dehydrogenase
700926 , M HYI hydroxypyruvate isomerase (putative)
701186 , Y SHMT1 serine hydroxymethyltransferase 1
704094 , M MCEE methylmalonyl-CoA epimerase
705060 , M ACSS1 acyl-CoA synthetase short chain family member 1
705075 , Y ACO1 aconitase 1
706189 , Y MMUT methylmalonyl-CoA mutase
706515 , M AMT aminomethyltransferase
706661 , M HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
706703 , Y ACSS2 acyl-CoA synthetase short chain family member 2
707441 , M ACO2 aconitase 2
707653 , M ACAT1 acetyl-CoA acetyltransferase 1
709604 , M CS citrate synthase
712615 , K HAO2 hydroxyacid oxidase 2
714433 , Y SHMT2 serine hydroxymethyltransferase 2
715153 , M AFMID arylformamidase
715563 , M GLDC glycine decarboxylase
715952 , Y GLUL glutamate-ammonia ligase
716964 , M PCCB propionyl-CoA carboxylase subunit beta
717406 , Y CAT catalase
717440 , M GCSH glycine cleavage system protein H
718360 , Y HAO1 hydroxyacid oxidase 1
719983 , M MDH2 malate dehydrogenase 2
100427660 , X ACAT2 acetyl-CoA acetyltransferase 2
106997075 , S LOC106997075 methylmalonyl-CoA epimerase, mitochondrial-like


List of genes in cfa


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
403443 , Y GLUL glutamate-ammonia ligase
403474 , Y CAT catalase
403978 , M DLD dihydrolipoamide dehydrogenase
474403 , M CS citrate synthase
474487 , M ACO2 aconitase 2
474614 , Y MDH1 malate dehydrogenase 1
474930 , M MMUT methylmalonyl-CoA mutase
475814 , Y HAO2 hydroxyacid oxidase 2
476975 , Y PCCA propionyl-CoA carboxylase subunit alpha
477002 , M ACSS1 acyl-CoA synthetase short chain family member 1
477076 , M PCCB propionyl-CoA carboxylase subunit beta
477205 , Y ACSS2 acyl-CoA synthetase short chain family member 2
479018 , S MCEE methylmalonyl-CoA epimerase
479633 , M GCSH glycine cleavage system protein H
481534 , M GLDC glycine decarboxylase
481576 , Y ACO1 aconitase 1
482531 , M HYI hydroxypyruvate isomerase (putative)
482945 , M MDH2 malate dehydrogenase 2
484063 , X ACAT2 acetyl-CoA acetyltransferase 2
484738 , M GLYCTK glycerate kinase
484770 , M AMT aminomethyltransferase
485342 , Y LOC485342 aminomethyltransferase, mitochondrial-like
485774 , Y HAO1 hydroxyacid oxidase 1
489421 , M ACAT1 acetyl-CoA acetyltransferase 1
489536 , Y SHMT1 serine hydroxymethyltransferase 1
607458 , Y SHMT2 serine hydroxymethyltransferase 2
608755 , M HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
612041 , M GRHPR glyoxylate and hydroxypyruvate reductase
612295 , Y LOC612295 glutamine synthetase-like
100855679 , M AGXT alanine--glyoxylate and serine--pyruvate aminotransferase
102151507 , Y LOC102151507 malate dehydrogenase, mitochondrial-like
102152275 , Y LOC102152275 malate dehydrogenase, mitochondrial-like
119863893 , M AFMID arylformamidase


List of genes in sce


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
850361 , N CIT2 citrate (Si)-synthase CIT2
850514 , Y AGX1 alanine--glyoxylate transaminase
850527 , M LPD1 dihydrolipoyl dehydrogenase
850747 , Y SHM2 glycine hydroxymethyltransferase SHM2
850846 , Y ACS2 acetate--CoA ligase ACS2
851013 , Y ACO1 aconitate hydratase ACO1
851245 , Y ACS1 acetate--CoA ligase 1
851254 , M GCV3 glycine decarboxylase subunit H
851481 , Y MDH3 malate dehydrogenase MDH3
851582 , M GCV1 glycine decarboxylase subunit T
851843 , Y_N CTA1 catalase A
852038 , N BNA7 arylformamidase
852523 , Y PCS60 Pcs60p
852565 , M SHM1 glycine hydroxymethyltransferase SHM1
852979 , Y_N CTT1 catalase T
853119 , Y_N TDA10 putative ATP-dependent kinase
853777 , Y MDH1 malate dehydrogenase MDH1
853994 , Y MDH2 malate dehydrogenase MDH2
854570 , Y FDH1 formate dehydrogenase (NAD+)
854849 , Y_X DAL7 malate synthase DAL7
855227 , M GCV2 glycine decarboxylase subunit P
855447 , Y GOR1 glyoxylate reductase
855606 , N MLS1 malate synthase MLS1
855732 , M CIT1 citrate (Si)-synthase CIT1
856079 , Y ERG10 acetyl-CoA C-acetyltransferase
856107 , M CIT3 citrate (Si)-synthase CIT3
856114 , M ICL2 methylisocitrate lyase ICL2
856147 , Y GLN1 glutamate--ammonia ligase
856794 , Y ICL1 isocitrate lyase 1


List of genes in spo


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
2538766 , M SPCC306.08c putative malate dehydrogenase
2539253 , Y SPCC1827.03c putative acetyl-CoA ligase
2539418 , Y_N ctt1 catalase
2539546 , Y SPCC191.02c putative acetyl-CoA ligase
2539803 , Y SPBC1683.11c putative isocitrate lyase
2540616 , Y erg10 putative acetyl-CoA C-acetyltransferase Erg10
2541294 , M gcv3 putative glycine decarboxylase complex subunit H
2541450 , M SPAC24C9.06c putative aconitate hydratase
2541752 , Y gln1 glutamate-ammonia ligase Gln1
2542242 , M shm2 putative serine hydroxymethyltransferase Shm2
2542594 , Y SPACUNK4.10 putative glyoxylate reductase
2542651 , Y SPAC24C9.12c putative glycine hydroxymethyltransferase
2542828 , M gcv2 putative glycine cleavage complex subunit P
2543137 , Y SPAC869.04 putative formamidase-like protein
2543195 , M gcv1 putative glycine decarboxylase T subunit gcv1
2543269 , M dld1 dihydrolipoamide dehydrogenase Dld1
2543283 , M cit1 citrate synthase Cit1
2543381 , N mug58 putative glycerate kinase


List of genes in fca


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
493924 , Y MDH1 malate dehydrogenase 1
727692 , M AGXT alanine--glyoxylate and serine--pyruvate aminotransferase
751515 , M CS citrate synthase
100302391 , M GRHPR glyoxylate and hydroxypyruvate reductase
101080758 , M PCCA propionyl-CoA carboxylase subunit alpha
101081046 , Y MMUT methylmalonyl-CoA mutase
101081096 , N AFMID arylformamidase
101081514 , S PGP phosphoglycolate phosphatase
101081790 , M GLYCTK glycerate kinase
101082847 , M PCCB propionyl-CoA carboxylase subunit beta
101083834 , Y ACSS2 acyl-CoA synthetase short chain family member 2
101084333 , M GCSH glycine cleavage system protein H
101084781 , M AMT aminomethyltransferase
101084845 , M MDH2 malate dehydrogenase 2
101085468 , M MCEE methylmalonyl-CoA epimerase
101086266 , Y_N SHMT1 serine hydroxymethyltransferase 1
101088259 , K HAO2 hydroxyacid oxidase 2
101088778 , M ACAT1 acetyl-CoA acetyltransferase 1
101089092 , Y_N ACSS1 acyl-CoA synthetase short chain family member 1
101089762 , Y HAO1 hydroxyacid oxidase 1
101091290 , M SHMT2 serine hydroxymethyltransferase 2
101093325 , Y GLUL glutamate-ammonia ligase
101093863 , X ACAT2 acetyl-CoA acetyltransferase 2
101093891 , Y CAT catalase
101094004 , M DLD dihydrolipoamide dehydrogenase
101095526 , Y ACO1 aconitase 1
101098729 , M HYI hydroxypyruvate isomerase (putative)
101100163 , M GLDC glycine decarboxylase
101101395 , M ACO2 aconitase 2
101101417 , M HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
102899556 , M LOC102899556 glycine cleavage system H protein, mitochondrial-like


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