Ortholog ID: 323
Species hsa hsa mmu mmu rno rno gga gga dre dre dme cel mcc mcc cfa cfa fca fca
Symbol PDK1 PDK4 Pdk1 Pdk4 Pdk4 Pdk1 PDK4 PDK3 pdk2b pdk4 Pdk pdhk-2 PDK4 PDK3 PDK1 PDK2 PDK1 PDK3
Function* pyruvate dehydrogenase kinase 1 pyruvate dehydrogenase kinase 4 pyruvate dehydrogenase kinase, isoenzyme 1 pyruvate dehydrogenase kinase, isoenzyme 4 pyruvate dehydrogenase kinase 4 pyruvate dehydrogenase kinase 1 pyruvate dehydrogenase kinase 4 pyruvate dehydrogenase kinase 3 pyruvate dehydrogenase kinase 2b pyruvate dehydrogenase kinase, isozyme 4 Pyruvate dehydrogenase kinase putative [pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial pyruvate dehydrogenase kinase 4 pyruvate dehydrogenase kinase 3 pyruvate dehydrogenase kinase 1 pyruvate dehydrogenase kinase 2 pyruvate dehydrogenase kinase 1 pyruvate dehydrogenase kinase 3
Expression Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples Expression pattern for all samples
Umap
Coexpression
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa00010 Glycolysis / Gluconeogenesis 8
hsa01200 Carbon metabolism 7
hsa04066 HIF-1 signaling pathway 7
hsa05230 Central carbon metabolism in cancer 5
hsa01230 Biosynthesis of amino acids 5
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa03320 PPAR signaling pathway 6
hsa00071 Fatty acid degradation 5
hsa01212 Fatty acid metabolism 5
hsa04714 Thermogenesis 3
hsa00280 Valine, leucine and isoleucine degradation 3
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04066 HIF-1 signaling pathway 7
mmu00010 Glycolysis / Gluconeogenesis 7
mmu05230 Central carbon metabolism in cancer 6
mmu04922 Glucagon signaling pathway 5
mmu01200 Carbon metabolism 5
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu03320 PPAR signaling pathway 7
mmu00280 Valine, leucine and isoleucine degradation 2
mmu05415 Diabetic cardiomyopathy 2
mmu00062 Fatty acid elongation 2
mmu00071 Fatty acid degradation 2
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno03320 PPAR signaling pathway 2
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno00190 Oxidative phosphorylation 7
rno04714 Thermogenesis 7
rno05010 Alzheimer disease 6
rno05012 Parkinson disease 6
rno05014 Amyotrophic lateral sclerosis 6
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04068 FoxO signaling pathway 2
gga04140 Autophagy - animal 2
gga04920 Adipocytokine signaling pathway 2
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga00190 Oxidative phosphorylation 3
gga04260 Cardiac muscle contraction 2
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre04150 mTOR signaling pathway 2
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre04910 Insulin signaling pathway 3
dre04068 FoxO signaling pathway 3
dre04137 Mitophagy - animal 3
dre03320 PPAR signaling pathway 2
dre04920 Adipocytokine signaling pathway 2
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dme00564 Glycerophospholipid metabolism 2
dme04120 Ubiquitin mediated proteolysis 2
dme04137 Mitophagy - animal 2
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cel04140 Autophagy - animal 3
cel04020 Calcium signaling pathway 2
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc00071 Fatty acid degradation 4
mcc01212 Fatty acid metabolism 4
mcc03320 PPAR signaling pathway 3
mcc05166 Human T-cell leukemia virus 1 infection 2
mcc05167 Kaposi sarcoma-associated herpesvirus infection 2
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc05415 Diabetic cardiomyopathy 4
mcc05014 Amyotrophic lateral sclerosis 4
mcc05022 Pathways of neurodegeneration - multiple diseases 4
mcc00190 Oxidative phosphorylation 3
mcc04714 Thermogenesis 3
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04066 HIF-1 signaling pathway 9
cfa00010 Glycolysis / Gluconeogenesis 7
cfa05230 Central carbon metabolism in cancer 6
cfa01200 Carbon metabolism 6
cfa01230 Biosynthesis of amino acids 6
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04722 Neurotrophin signaling pathway 2
cfa05022 Pathways of neurodegeneration - multiple diseases 2
cfa04137 Mitophagy - animal 2
cfa04920 Adipocytokine signaling pathway 2
cfa04510 Focal adhesion 2
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca01200 Carbon metabolism 6
fca05014 Amyotrophic lateral sclerosis 5
fca00020 Citrate cycle (TCA cycle) 5
fca05010 Alzheimer disease 4
fca05012 Parkinson disease 4
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca05168 Herpes simplex virus 1 infection 2
fca04144 Endocytosis 2
GO BP*
GO:0097411 [L] [N] hypoxia-inducible factor-1alpha signaling pathway  (5 genes)
GO:0010510 [L] [N] regulation of acetyl-CoA biosynthetic process from pyruvate  (8 genes)
GO:0008631 [L] [N] intrinsic apoptotic signaling pathway in response to oxidative stress  (15 genes)
GO:0010906 [L] [N] regulation of glucose metabolic process  (23 genes)
GO:0006006 [L] [N] glucose metabolic process  (55 genes)
GO:0008283 [L] [N] cell population proliferation  (132 genes)
GO:0006468 [L] [N] protein phosphorylation  (472 genes)
GO:0046320 [L] [N] regulation of fatty acid oxidation  (3 genes)
GO:0010565 [L] [N] regulation of cellular ketone metabolic process  (4 genes)
GO:0010510 [L] [N] regulation of acetyl-CoA biosynthetic process from pyruvate  (8 genes)
GO:0045124 [L] [N] regulation of bone resorption  (9 genes)
GO:0042304 [L] [N] regulation of fatty acid biosynthetic process  (10 genes)
GO:0006885 [L] [N] regulation of pH  (12 genes)
GO:2000811 [L] [N] negative regulation of anoikis  (17 genes)
GO:0010906 [L] [N] regulation of glucose metabolic process  (23 genes)
GO:0071398 [L] [N] cellular response to fatty acid  (26 genes)
GO:0072593 [L] [N] reactive oxygen species metabolic process  (31 genes)
GO:0042594 [L] [N] response to starvation  (39 genes)
GO:0006006 [L] [N] glucose metabolic process  (55 genes)
GO:0009267 [L] [N] cellular response to starvation  (68 genes)
GO:0008286 [L] [N] insulin receptor signaling pathway  (84 genes)
GO:0042593 [L] [N] glucose homeostasis  (105 genes)
GO:0006468 [L] [N] protein phosphorylation  (472 genes)
GO:0097411 [L] [N] hypoxia-inducible factor-1alpha signaling pathway  (3 genes)
GO:0010510 [L] [N] regulation of acetyl-CoA biosynthetic process from pyruvate  (4 genes)
GO:0008631 [L] [N] intrinsic apoptotic signaling pathway in response to oxidative stress  (18 genes)
GO:0010906 [L] [N] regulation of glucose metabolic process  (30 genes)
GO:0006006 [L] [N] glucose metabolic process  (77 genes)
GO:0008283 [L] [N] cell population proliferation  (167 genes)
GO:0018105 [L] [N] peptidyl-serine phosphorylation  (173 genes)
GO:0007166 [L] [N] cell surface receptor signaling pathway  (186 genes)
GO:0005975 [L] [N] carbohydrate metabolic process  (199 genes)
GO:0035556 [L] [N] intracellular signal transduction  (429 genes)
GO:0006468 [L] [N] protein phosphorylation  (564 genes)
GO:0016310 [L] [N] phosphorylation  (594 genes)
GO:0010510 [L] [N] regulation of acetyl-CoA biosynthetic process from pyruvate  (4 genes)
GO:0010565 [L] [N] regulation of cellular ketone metabolic process  (4 genes)
GO:0042304 [L] [N] regulation of fatty acid biosynthetic process  (4 genes)
GO:0046320 [L] [N] regulation of fatty acid oxidation  (4 genes)
GO:0045124 [L] [N] regulation of bone resorption  (8 genes)
GO:0071398 [L] [N] cellular response to fatty acid  (12 genes)
GO:2000811 [L] [N] negative regulation of anoikis  (15 genes)
GO:0042594 [L] [N] response to starvation  (20 genes)
GO:0006885 [L] [N] regulation of pH  (26 genes)
GO:0010906 [L] [N] regulation of glucose metabolic process  (30 genes)
GO:0072593 [L] [N] reactive oxygen species metabolic process  (41 genes)
GO:0008286 [L] [N] insulin receptor signaling pathway  (57 genes)
GO:0009267 [L] [N] cellular response to starvation  (74 genes)
GO:0006006 [L] [N] glucose metabolic process  (77 genes)
GO:0042593 [L] [N] glucose homeostasis  (150 genes)
GO:0005975 [L] [N] carbohydrate metabolic process  (199 genes)
GO:0006468 [L] [N] protein phosphorylation  (564 genes)
GO:0016310 [L] [N] phosphorylation  (594 genes)
GO:0010510 [L] [N] regulation of acetyl-CoA biosynthetic process from pyruvate  (4 genes)
GO:0010565 [L] [N] regulation of cellular ketone metabolic process  (4 genes)
GO:0042304 [L] [N] regulation of fatty acid biosynthetic process  (4 genes)
GO:0046320 [L] [N] regulation of fatty acid oxidation  (4 genes)
GO:0006086 [L] [N] acetyl-CoA biosynthetic process from pyruvate  (7 genes)
GO:0045124 [L] [N] regulation of bone resorption  (8 genes)
GO:2000811 [L] [N] negative regulation of anoikis  (16 genes)
GO:0006885 [L] [N] regulation of pH  (22 genes)
GO:0010906 [L] [N] regulation of glucose metabolic process  (30 genes)
GO:0071398 [L] [N] cellular response to fatty acid  (35 genes)
GO:0072593 [L] [N] reactive oxygen species metabolic process  (38 genes)
GO:0008286 [L] [N] insulin receptor signaling pathway  (61 genes)
GO:0042594 [L] [N] response to starvation  (62 genes)
GO:0006006 [L] [N] glucose metabolic process  (70 genes)
GO:0009267 [L] [N] cellular response to starvation  (81 genes)
GO:0042593 [L] [N] glucose homeostasis  (146 genes)
GO:0006468 [L] [N] protein phosphorylation  (491 genes)
GO:0010510 [L] [N] regulation of acetyl-CoA biosynthetic process from pyruvate  (4 genes)
GO:0097411 [L] [N] hypoxia-inducible factor-1alpha signaling pathway  (4 genes)
GO:0008631 [L] [N] intrinsic apoptotic signaling pathway in response to oxidative stress  (19 genes)
GO:0010906 [L] [N] regulation of glucose metabolic process  (30 genes)
GO:0006006 [L] [N] glucose metabolic process  (70 genes)
GO:0007166 [L] [N] cell surface receptor signaling pathway  (141 genes)
GO:0018105 [L] [N] peptidyl-serine phosphorylation  (171 genes)
GO:0008283 [L] [N] cell population proliferation  (179 genes)
GO:0006468 [L] [N] protein phosphorylation  (491 genes)
GO:0010906 [L] [N] regulation of glucose metabolic process  (9 genes)
GO:0016310 [L] [N] phosphorylation  (716 genes)
GO:0006468 [L] [N] protein phosphorylation  (732 genes)
GO:0010906 [L] [N] regulation of glucose metabolic process  (9 genes)
GO:0016310 [L] [N] phosphorylation  (716 genes)
GO:0006468 [L] [N] protein phosphorylation  (732 genes)
GO:0010906 [L] [N] regulation of glucose metabolic process  (2 genes)
GO:0006468 [L] [N] protein phosphorylation  (190 genes)
GO:0010906 [L] [N] regulation of glucose metabolic process  (1 genes)
GO:0006006 [L] [N] glucose metabolic process  (12 genes)
GO:0005975 [L] [N] carbohydrate metabolic process  (155 genes)
GO:0006468 [L] [N] protein phosphorylation  (422 genes)
GO:0016310 [L] [N] phosphorylation  (480 genes)
GO CC*
GO:0005967 [L] [N] mitochondrial pyruvate dehydrogenase complex  (4 genes)
GO:0005759 [L] [N] mitochondrial matrix  (380 genes)
GO:0005739 [L] [N] mitochondrion  (1320 genes)
GO:0005759 [L] [N] mitochondrial matrix  (380 genes)
GO:0005739 [L] [N] mitochondrion  (1320 genes)
GO:0005967 [L] [N] mitochondrial pyruvate dehydrogenase complex  (4 genes)
GO:0045254 [L] [N] pyruvate dehydrogenase complex  (8 genes)
GO:0005739 [L] [N] mitochondrion  (1808 genes)
GO:0005886 [L] [N] plasma membrane  (4367 genes)
GO:0005743 [L] [N] mitochondrial inner membrane  (420 genes)
GO:0005739 [L] [N] mitochondrion  (1808 genes)
GO:0005759 [L] [N] mitochondrial matrix  (186 genes)
GO:0005739 [L] [N] mitochondrion  (1331 genes)
GO:0005967 [L] [N] mitochondrial pyruvate dehydrogenase complex  (5 genes)
GO:0045254 [L] [N] pyruvate dehydrogenase complex  (8 genes)
GO:0005739 [L] [N] mitochondrion  (1331 genes)
GO:0005759 [L] [N] mitochondrial matrix  (76 genes)
GO:0005739 [L] [N] mitochondrion  (817 genes)
GO:0005759 [L] [N] mitochondrial matrix  (76 genes)
GO:0005739 [L] [N] mitochondrion  (817 genes)
GO:0005967 [L] [N] mitochondrial pyruvate dehydrogenase complex  (5 genes)
GO:0005739 [L] [N] mitochondrion  (554 genes)
GO:0005759 [L] [N] mitochondrial matrix  (66 genes)
GO:0048471 [L] [N] perinuclear region of cytoplasm  (95 genes)
GO:0005739 [L] [N] mitochondrion  (592 genes)
GO:0005737 [L] [N] cytoplasm  (2113 genes)
GO MF*
GO:0004740 [L] [N] pyruvate dehydrogenase (acetyl-transferring) kinase activity  (5 genes)
GO:0004672 [L] [N] protein kinase activity  (219 genes)
GO:0005524 [L] [N] ATP binding  (1474 genes)
GO:0005515 [L] [N] protein binding  (12443 genes)
GO:0004740 [L] [N] pyruvate dehydrogenase (acetyl-transferring) kinase activity  (5 genes)
GO:0004672 [L] [N] protein kinase activity  (219 genes)
GO:0005524 [L] [N] ATP binding  (1474 genes)
GO:0005515 [L] [N] protein binding  (12443 genes)
GO:0004740 [L] [N] pyruvate dehydrogenase (acetyl-transferring) kinase activity  (5 genes)
GO:0004674 [L] [N] protein serine/threonine kinase activity  (417 genes)
GO:0004672 [L] [N] protein kinase activity  (510 genes)
GO:0016301 [L] [N] kinase activity  (621 genes)
GO:0044877 [L] [N] protein-containing complex binding  (630 genes)
GO:0005524 [L] [N] ATP binding  (1396 genes)
GO:0000166 [L] [N] nucleotide binding  (1699 genes)
GO:0016740 [L] [N] transferase activity  (1746 genes)
GO:0042802 [L] [N] identical protein binding  (1906 genes)
GO:0004740 [L] [N] pyruvate dehydrogenase (acetyl-transferring) kinase activity  (5 genes)
GO:0004712 [L] [N] protein serine/threonine/tyrosine kinase activity  (29 genes)
GO:0004672 [L] [N] protein kinase activity  (510 genes)
GO:0016301 [L] [N] kinase activity  (621 genes)
GO:0005524 [L] [N] ATP binding  (1396 genes)
GO:0000166 [L] [N] nucleotide binding  (1699 genes)
GO:0016740 [L] [N] transferase activity  (1746 genes)
GO:0004740 [L] [N] pyruvate dehydrogenase (acetyl-transferring) kinase activity  (5 genes)
GO:0004672 [L] [N] protein kinase activity  (255 genes)
GO:0005524 [L] [N] ATP binding  (1380 genes)
GO:0004740 [L] [N] pyruvate dehydrogenase (acetyl-transferring) kinase activity  (5 genes)
GO:0004672 [L] [N] protein kinase activity  (255 genes)
GO:0004674 [L] [N] protein serine/threonine kinase activity  (311 genes)
GO:0044877 [L] [N] protein-containing complex binding  (647 genes)
GO:0005524 [L] [N] ATP binding  (1380 genes)
GO:0005515 [L] [N] protein binding  (1723 genes)
GO:0042802 [L] [N] identical protein binding  (1829 genes)
GO:0004740 [L] [N] pyruvate dehydrogenase (acetyl-transferring) kinase activity  (7 genes)
GO:0004674 [L] [N] protein serine/threonine kinase activity  (521 genes)
GO:0004672 [L] [N] protein kinase activity  (713 genes)
GO:0016301 [L] [N] kinase activity  (716 genes)
GO:0005524 [L] [N] ATP binding  (1578 genes)
GO:0000166 [L] [N] nucleotide binding  (1694 genes)
GO:0016740 [L] [N] transferase activity  (1739 genes)
GO:0004740 [L] [N] pyruvate dehydrogenase (acetyl-transferring) kinase activity  (7 genes)
GO:0016772 [L] [N] transferase activity, transferring phosphorus-containing groups  (27 genes)
GO:0004674 [L] [N] protein serine/threonine kinase activity  (521 genes)
GO:0004672 [L] [N] protein kinase activity  (713 genes)
GO:0016301 [L] [N] kinase activity  (716 genes)
GO:0005524 [L] [N] ATP binding  (1578 genes)
GO:0000166 [L] [N] nucleotide binding  (1694 genes)
GO:0016740 [L] [N] transferase activity  (1739 genes)
GO:0004740 [L] [N] pyruvate dehydrogenase (acetyl-transferring) kinase activity  (1 genes)
GO:0004672 [L] [N] protein kinase activity  (79 genes)
GO:0004740 [L] [N] pyruvate dehydrogenase (acetyl-transferring) kinase activity  (1 genes)
GO:0004672 [L] [N] protein kinase activity  (401 genes)
GO:0016301 [L] [N] kinase activity  (473 genes)
GO:0005524 [L] [N] ATP binding  (939 genes)
GO:0000166 [L] [N] nucleotide binding  (977 genes)
GO:0016740 [L] [N] transferase activity  (1062 genes)
KEGG*
04066 HIF-1 signaling pathway genomenet
05230 Central carbon metabolism in cancer genomenet
05415 Diabetic cardiomyopathy genomenet
04066 HIF-1 signaling pathway genomenet
05230 Central carbon metabolism in cancer genomenet
05415 Diabetic cardiomyopathy genomenet
05415 Diabetic cardiomyopathy genomenet
04066 HIF-1 signaling pathway genomenet
05230 Central carbon metabolism in cancer genomenet
05415 Diabetic cardiomyopathy genomenet
05415 Diabetic cardiomyopathy genomenet
04066 HIF-1 signaling pathway genomenet
05230 Central carbon metabolism in cancer genomenet
05415 Diabetic cardiomyopathy genomenet
04066 HIF-1 signaling pathway genomenet
05230 Central carbon metabolism in cancer genomenet
05415 Diabetic cardiomyopathy genomenet
Entrez Gene ID* 5163 5166 228026 27273 89813 116551 420570 418595 393971 561007 35970 176226 698726 699394 476828 491075 101092705 101095314


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