Orthologous genes in OrthoFinder**

Species Gene Description
 sce-u.3   PYC2   pyruvate carboxylase 2 
 sce-r.3   PYC2   pyruvate carboxylase 2 
 sce-m.4   PYC2   pyruvate carboxylase 2 
 sce-u.3   PYC1   pyruvate carboxylase 1 
 spo-u.3   SPBC26H8.16   hypothetical protein 
 hsa-u.4   PC   pyruvate carboxylase 
 mmu-u.4   Pcx   pyruvate carboxylase 
 rno-u.3   Pc   pyruvate carboxylase 
 gga-u.3   PC   pyruvate carboxylase 
 dre-u.3   pcxa   pyruvate carboxylase a 
 dre-u.3   pcxb   pyruvate carboxylase b 
 dme-u.3   PCB   Pyruvate carboxylase 
 cel-u.3   pyc-1   Pyruvate carboxylase 1 
 mcc-u.3   PC   pyruvate carboxylase 
 cfa-u.3   PC   pyruvate carboxylase 

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Top 50 coexpressed genes to PYC2 (sce-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 sce1230   Biosynthesis of amino acids  32 122 6.09
 sce1210   2-Oxocarboxylic acid metabolism  12 35 6.36
 sce400   Phenylalanine, tyrosine and tryptophan biosynthesis  10 17 6.62
 sce970   Aminoacyl-tRNA biosynthesis  7 40 6.00
 sce250   Alanine, aspartate and glutamate metabolism  6 28 6.97

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sce:PYC2 (pyruvate carboxylase 2) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

sce-u.3
for
PYC2
sce-r.3
for
PYC2
sce-m.4
for
PYC2
sce-u.3
for
PYC1
spo-u.3
for
SPBC26H8.16
hsa-u.4
for
PC
mmu-u.4
for
Pcx
rno-u.3
for
Pc
gga-u.3
for
PC
dre-u.3
for
pcxa
dre-u.3
for
pcxb
dme-u.3
for
PCB
cel-u.3
for
pyc-1
mcc-u.3
for
PC
cfa-u.3
for
PC
1 ARO1 pentafunctional protein ARO1p 851705 YDR127W 7.9 4.2
 3.4
 1.7




-0.2
-1.3
 -0.3
-1.7



2 ARO3 3-deoxy-7-phosphoheptulonate synthase ARO3 851605 YDR035W 6.6 3.4
 2.9











3 ILS1 isoleucine--tRNA ligase ILS1 852202 YBL076C 6.4 3.2
 2.9
 1.1
 0.4
 0.6
 0.7
 -0.3
 -1.3
 0.1
 0.0
 0.0
 1.5
 0.2
 0.6
4 CPA2 carbamoyl-phosphate synthase (glutamine-hydrolyzing) CPA2 853573 YJR109C 6.4 3.5
 2.7
 3.3
2.6
 0.7
 2.4
0.7
 1.6
-0.2
 2.3
-1.3
 1.2
1.0
 1.2
0.8
 2.2
-0.1
 0.5
 2.4
 2.2
-0.0
 1.3
-0.6
5 HIS4 trifunctional histidinol dehydrogenase/phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 850327 YCL030C 6.3 3.7
 2.4
 -0.4
 -0.4









6 ARG7 glutamate N-acetyltransferase 855084 YMR062C 6.3 2.9
 3.1
 -0.5
 0.7









7 ARO4 3-deoxy-7-phosphoheptulonate synthase ARO4 852551 YBR249C 6.0 3.0
 2.8
 -0.5
 1.0









8 TRP5 tryptophan synthase TRP5 852858 YGL026C 6.0 3.8
 2.0
 0.0










9 ILV6 acetolactate synthase regulatory subunit 850348 YCL009C 6.0 3.1
 2.7
 -0.1
 -0.2









10 HOM2 aspartate-semialdehyde dehydrogenase 851736 YDR158W 5.8 2.6
 2.9
 -0.3
 -0.8









11 VAS1 valine--tRNA ligase 852986 YGR094W 5.5 2.9
 2.5
 1.1
 0.2
 2.0
1.4
 2.4
1.3
 0.8
0.7
 3.3
2.4
 1.8
0.9
 0.7
-0.1
 0.2
0.2
 1.8
0.9
 2.3
1.4
 1.7
0.2
12 URA2 bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase 853311 YJL130C 5.3 3.0
3.3
2.6
 0.7
 2.4
0.7
 1.6
-0.2
 2.3
-1.3
 1.2
1.0
 1.2
0.8
 2.2
-0.1
 0.5
 2.4
 2.2
-0.0
 1.3
-0.6
13 ARG5,6 bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase 856800 YER069W 5.3 2.9
 2.2
 -0.6
1.9
 0.7
 -0.6






14 GGC1 Ggc1p 851329 YDL198C 5.2 2.5
 2.5
 0.9
 0.0









15 GLT1 glutamate synthase (NADH) 851383 YDL171C 5.1 2.7
 2.3
 1.0






3.6
 3.4

16 LYS2 L-aminoadipate-semialdehyde dehydrogenase 852412 YBR115C 4.9 2.6
 2.2
 0.1






0.6
0.4
 -0.2

17 ARG1 argininosuccinate synthase 854096 YOL058W 4.9 2.8
0.5
2.9
 2.3
 0.8
 -0.1
 0.1
 1.6
 1.5
0.6
 0.2
18 ACO2 aconitate hydratase ACO2 853230 YJL200C 4.9 3.0
 1.8
 2.6
-1.0
3.1
 4.3
 2.7
 0.9
 0.9
 0.2
 2.5
-0.2
 6.4
 3.4
 1.4
19 TRP3 bifunctional anthranilate synthase/indole-3-glycerol-phosphate synthase 853669 YKL211C 4.8 3.0
 1.7
 0.1
 0.4









20 ILV1 threonine ammonia-lyase ILV1 856819 YER086W 4.8 2.8
 1.9
 -0.0
-0.2
0.3
 -0.3
 1.1
 0.4
0.2
 0.8
-0.9
 -0.1
-0.6
 2.3
 0.9
0.5
 -0.7
 -2.2
21 ARO8 bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase 852672 YGL202W 4.7 2.9
 1.7
 1.1
0.5
-0.6
 0.0
 2.2
 0.4
 1.6
 -0.2
 1.5
0.3
 1.2
22 DPS1 aspartate--tRNA ligase DPS1 850643 YLL018C 4.7 2.5
 2.1
 -0.1
 -0.1
 -0.3
 0.8
 -0.3
 -0.4
 0.7
 -0.3
 -0.7
 0.3
 -2.2
 -2.0
23 ADE6 phosphoribosylformylglycinamidine synthase 852952 YGR061C 4.7 2.3
 2.3
 0.6
 -0.9
 1.7
 0.2
 0.6
 3.4
 3.2
 3.6
 3.7
 0.7
 0.5
 2.7
24 ARG4 argininosuccinate lyase ARG4 856411 YHR018C 4.7 2.6
 1.9
 0.2
 1.3
 2.8
 1.8
 2.0
 -0.2
-0.3
 0.2
 -0.5
 3.4
1.1
 -1.4
25 YHR020W proline--tRNA ligase 856413 YHR020W 4.6 2.4
 2.0
 1.1
0.1
 1.8
-0.3
 0.4
 1.0
 0.7
 -0.8
 1.4
 -0.7
 0.1
 2.0
0.4
 -1.0
 1.2
26 TRP4 anthranilate phosphoribosyltransferase 851956 YDR354W 4.6 2.4
 2.0
 -0.6
 1.3









27 YDR341C arginine--tRNA ligase 851942 YDR341C 4.6 2.6
 1.8
 0.9
-0.6
 -0.7
 -0.8
 0.1
 -0.7
 -1.2
 0.7
 -0.4
 -0.5
 -0.4
 -0.6
 -1.5
28 LYS4 homoaconitate hydratase LYS4 851820 YDR234W 4.4 2.1
 2.2
 -0.4










29 AAP1 arginine/alanine aminopeptidase 856443 YHR047C 4.4 2.5
 1.8
 1.2
-1.0
 1.0
 0.3
 0.2
 1.2
 1.3
 2.2
 0.2
 0.4
 3.3
 -0.2
 -0.6
30 ASN1 asparagine synthase (glutamine-hydrolyzing) 1 856268 YPR145W 4.4 2.8
 1.5
 0.9
0.5
-1.0
 1.3
 0.9
 -0.9
 1.6
 1.1
 2.8
 4.8
-0.6
 -0.9
 1.4
31 DED81 asparagine--tRNA ligase DED81 856412 YHR019C 4.3 2.6
 1.7
 -0.1
 -0.6
 -0.4
 -0.0
 -0.4
 -0.3
 0.1
 -1.4
 0.7
 0.3
 0.5
 0.5
32 LEU9 2-isopropylmalate synthase LEU9 854275 YOR108W 4.3 2.2
 2.0
 1.6
0.1










33 TRP2 anthranilate synthase TRP2 856824 YER090W 4.2 2.2
 1.9
 -0.9










34 HOM3 aspartate kinase 856778 YER052C 4.2 2.1
 2.1
 0.0










35 YMC1 organic acid transporter 856171 YPR058W 4.2 1.8
 2.3
 3.4
0.4
1.3
 0.3
 1.1
 2.0
 -0.0
 3.5
 2.9
-1.1
 2.1
0.0
 0.8
 -1.3
36 LEU4 2-isopropylmalate synthase LEU4 855619 YNL104C 4.2 1.5
 2.5
 1.6
0.1










37 HIS1 ATP phosphoribosyltransferase 856782 YER055C 4.2 2.2
 1.9
 -1.2










38 ARO2 bifunctional chorismate synthase/riboflavin reductase [NAD(P)H] ARO2 852729 YGL148W 4.1 2.1
 1.9
 -0.3
 -0.4









39 CAF16 putative ATP-binding cassette family ATPase CAF16 850516 YFL028C 4.1 1.8
 2.2
 -1.1
-1.1




1.4
 0.3
 1.5
1.3


40 ILV3 dihydroxy-acid dehydratase ILV3 853473 YJR016C 4.1 1.7
 2.3
 -0.1
 0.6









41 HIS7 imidazoleglycerol-phosphate synthase 852550 YBR248C 4.0 2.4
 1.5
 -0.1
 0.7









42 ILV2 acetolactate synthase catalytic subunit 855135 YMR108W 4.0 1.8
 2.1
 1.0










43 YBT1 bile acid-transporting ATPase YBT1 850678 YLL048C 3.9 2.2
 1.6
 0.8
0.5
2.0
1.3
 1.1
1.0
 1.0
0.7
 2.5
1.3
 1.7
0.8
 4.6
1.1
 2.3
2.0
 1.2
1.2
 1.8
1.3
 3.0
1.7
44 THR4 threonine synthase THR4 850420 YCR053W 3.8 2.2
 1.5
 -0.1
1.3
 1.3
 1.0
 2.0
 0.6
 -0.1

1.3
 1.7
45 SCP160 Scp160p 853365 YJL080C 3.8 1.8
 1.9
 1.3
 -0.6
-1.5
 1.5
 1.1
 2.3
 0.7
 2.1
1.6
 0.0
-0.2
 1.3
 3.4
 1.5
 2.1
46 PRO2 glutamate-5-semialdehyde dehydrogenase 854501 YOR323C 3.8 1.9
 1.8
 0.0
 0.4
 1.2
 0.0
-0.6
 0.4
 -1.3
 3.2
 1.5
 -0.6
 1.6
47 HIS5 histidinol-phosphate transaminase 854690 YIL116W 3.8 2.1
 1.5
 -0.5
 -2.1









48 ADE3 trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 853118 YGR204W 3.7 2.1
 1.5
 3.0
-0.3
2.7
 3.0
0.5
 2.8
-0.0
 2.4
 1.6
-0.4
 3.0
2.7
 3.2
 4.2
 0.7
0.5
 3.5
0.3
49 CDC60 leucine--tRNA ligase CDC60 855943 YPL160W 3.7 2.3
 1.3
 0.4
 -0.1
 0.1
 0.5
 -0.3
 -1.5
 1.7
 0.6
 0.8
 1.1
 -1.4
 -0.2
50 PDX3 pyridoxamine-phosphate oxidase PDX3 852323 YBR035C 3.6 1.7
 1.8
 0.7
 0.2
 1.6
 2.0
 2.0
 2.2
 0.8
 0.5
 0.0
 2.2
 0.3
 1.9
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