Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   klb   klotho beta 
 dre-r.3   klb   klotho beta 
 hsa-u.4   KLB   klotho beta 
 mmu-u.4   Klb   klotho beta 
 rno-u.3   Klb   klotho beta 
 gga-u.3   KLB   klotho beta 
 mcc-u.3   KLB   klotho beta 

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Top 50 coexpressed genes to klb (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre61   Fatty acid biosynthesis  1 22 -
 dre52   Galactose metabolism  1 34 -
 dre260   Glycine, serine and threonine metabolism  1 47 -
 dre71   Fatty acid degradation  1 56 -
 dre230   Purine metabolism  1 165 -

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dre:klb (klotho beta) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
klb
dre-r.3
for
klb
hsa-u.4
for
KLB
mmu-u.4
for
Klb
rno-u.3
for
Klb
gga-u.3
for
KLB
mcc-u.3
for
KLB
1 st3gal7 ST3 beta-galactoside alpha-2,3-sialyltransferase 7 554166 5.2 2.7




2 cideb cell death inducing DFFA like effector b 553467 5.1 2.7
 4.7
2.6
 4.3
1.8
 4.0
1.6
 0.7
0.3
 2.3
1.0
3 LOC100537272 macrophage mannose receptor 1-like 100537272 5.0 2.6
 0.1
-0.6
 0.6
0.3
 1.5
0.8
 0.6
0.5
 1.1
1.0
4 pdzd3a PDZ domain containing 3a 557269 4.9 2.6
1.1
 -0.5
 -0.1
 0.6
5 slc13a2 solute carrier family 13 member 2 406537 4.8 2.5
 2.2
-0.3
 1.6
0.4
 0.8
0.6
 1.4
1.1
 2.8
0.4
6 adgrg4a adhesion G protein-coupled receptor G4a 793963 4.7 2.5
 0.9
0.3
 0.7
-0.0
 1.2
-1.0
 0.9
0.2
 0.6
-0.3
7 acsl5 acyl-CoA synthetase long chain family member 5 447860 4.6 2.4
 1.2
0.8
 2.2
0.3
 2.1
1.2
 1.6
1.5
 1.0
-0.4
8 LOC103908636 protocadherin Fat 3-like 103908636 4.6 2.4


2.2
9 creb3l3b cAMP responsive element binding protein 3-like 3b 100538072 4.5 2.4
 2.3
 3.0
 1.2
 2.9
 0.7
10 myo7bb myosin VIIBb 566034 4.5 2.4




11 hnf1a HNF1 homeobox a 266961 4.3 2.3
 3.9
 1.9
 1.7
 3.4
 1.2
12 slc15a1b solute carrier family 15 member 1b 793301 4.3 2.3
 1.2
-0.3
 -0.2
 -0.8
 1.0
-1.1
 -1.7
13 naaladl1 N-acetylated alpha-linked acidic dipeptidase like 1 100000223 4.3 2.2
 2.1
0.2
 0.7
0.2
 1.4
-0.1
 1.2
0.0
 1.2
0.3
14 zanl zonadhesin, like 100147904 4.3 2.3




15 anpepb alanyl (membrane) aminopeptidase b 322533 4.3 2.3
 0.4
0.2
 2.7
-0.6
 0.0
-0.7
 2.2
1.1
 0.6
0.1
16 epdl2 ependymin-like 2 557419 4.2 2.2




17 slc22a4 solute carrier family 22 member 4 393822 4.2 2.2
 4.2
1.8
 2.2
2.1
 1.8
1.2
 2.8
2.1
 1.4
1.3
18 enpep glutamyl aminopeptidase 504088 4.1 2.2
 0.4
0.2
 2.7
-0.6
 0.0
-0.7
 2.2
1.1
 0.6
0.1
19 zgc:110410 zgc:110410 553618 4.1 2.2
 -0.2
-0.7
 0.3
-0.4
 0.6
0.5
 0.7
-0.0
 -0.3
-1.1
20 cldn34a claudin 34a 568833 4.1 2.1


0.5
21 eps8l3a EPS8-like 3a 100334248 4.0 2.1
 1.1
 0.6
0.2
 0.0
22 slc22a7b.3 solute carrier family 22 member 7b, tandem duplicate 3 100001772 4.0 2.1
 4.2
1.8
 2.2
2.1
 1.8
1.2
 2.8
2.1
 1.4
1.3
23 gucy2ca guanylate cyclase 2Ca 572052 3.9 2.1
 1.4
 0.5
 0.8
 1.4
 0.9
24 stk24a serine/threonine kinase 24a (STE20 homolog, yeast) 555297 3.9 2.1
 0.1
-0.1
 -0.1
-0.7
 0.0
-0.3
 0.3
-0.3
 -0.2
-0.4
25 apobb.1 apolipoprotein Bb, tandem duplicate 1 321166 3.9 2.1
 5.0
 3.0
 1.4
 4.4
 0.7
26 abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 393561 3.9 2.1
 2.7
-0.2
 3.8
2.7
 1.9
0.8
 2.9
1.6
 0.8
0.6
27 dpp4 dipeptidyl-peptidase 4 100301982 3.9 2.1
 1.2
0.3
 1.6
0.2
 0.8
0.3
 1.0
0.4
 1.0
0.3
28 eps8l3b EPS8-like 3b 393332 3.8 2.0
 1.1
 0.6
0.2
 0.0
29 si:zfos-741a10.3 si:zfos-741a10.3 796591 3.8 2.0




30 si:ch211-122f10.4 si:ch211-122f10.4 792966 3.8 2.0
 -0.3
 0.4
 -1.6
 -0.8
 -0.9
31 wu:fa56d06 wu:fa56d06 795664 3.8 2.0




32 clrn3 clarin 3 100000502 3.7 2.0
 1.0
 0.7
 -0.4
 1.2
 -0.3
33 naalad2 N-acetylated alpha-linked acidic dipeptidase 2 393247 3.7 2.0
 2.1
0.2
 0.7
0.2
 1.4
-0.1
 1.2
0.0
 1.2
0.3
34 cuzd1.2 CUB and zona pellucida-like domains 1, tandem duplicate 2 555768 3.7 2.0
0.9
 -0.3
 -0.5
-0.5
35 slc6a19a.1 solute carrier family 6 member 19a, tandem duplicate 1 553256 3.7 2.0
 1.3
 0.4
0.2
 -0.7
-0.9
 2.0
1.3
 -0.4
36 pdzk1 PDZ domain containing 1 337325 3.7 2.0
 2.7
 2.7
 1.6
 3.0
 1.4
37 LOC559107 lactase-phlorizin hydrolase 559107 3.7 2.0
 1.4
 -0.1
2.3
 0.1
38 zgc:103681 zgc:103681 449773 3.7 1.9
 1.0
0.4
 2.3
1.6
 1.4
0.7
 -0.9
 0.0
-1.0
39 prr15la proline rich 15 like a 445084 3.6 1.9
 1.5
 0.0
 0.6
 -0.5
 0.8
40 si:ch211-196f2.3 si:ch211-196f2.3 566363 3.6 1.9
 0.2
0.1
 0.9
0.4
-0.3
-1.2
 0.3
0.2
41 slc2a2 solute carrier family 2 member 2 322493 3.6 1.9
 3.1
1.4
 3.6
2.9
 1.0
0.7
 3.2
2.7
 1.3
1.2
42 mep1a.2 meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2 565535 3.6 1.9
 2.1
1.7
 1.2
0.2
 -0.1
-0.4
 1.2
0.7
 1.4
0.9
43 si:ch211-235m3.5 si:ch211-235m3.5 101884886 3.6 1.9




44 apoa4b.2 apolipoprotein A-IV b, tandem duplicate 2 570354 3.6 1.9
 1.4
 0.9
 0.9
0.3
45 slc6a19a.2 solute carrier family 6 member 19a, tandem duplicate 2 100334171 3.5 1.9
 1.3
 0.4
0.2
 -0.7
-0.9
 2.0
1.3
 -0.4
46 chs1 chitin synthase 1 322468 3.5 1.9




47 slc28a1 solute carrier family 28 member 1 571287 3.5 1.9
0.6
0.1
 0.5
-0.0
 2.0
-0.3
 0.4
48 apoa4b.3 apolipoprotein A-IV b, tandem duplicate 3 100004607 3.5 1.9
 1.4
 0.9
 0.9
0.3
49 sdsl serine dehydratase-like 563642 3.5 1.9
 0.5
-0.1
 2.3
1.1
 0.5
0.1
 0.7
 0.6
-0.3
50 cdh17 cadherin 17, LI cadherin (liver-intestine) 378452 3.5 1.9
 1.0
 -0.1
 0.4
 2.3
 -0.7
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