Orthologous genes in OrthoFinder**

Species Gene Description
 mmu-u.4   Ticrr   TOPBP1-interacting checkpoint and replication regulator 
 mmu-r.6   Ticrr   TOPBP1-interacting checkpoint and replication regulator 
 mmu-m.5   Ticrr   TOPBP1-interacting checkpoint and replication regulator 
 rno-u.3   Ticrr   TOPBP1-interacting checkpoint and replication regulator 
 hsa-u.4   TICRR   TOPBP1 interacting checkpoint and replication regulator 
 mcc-u.3   TICRR   TOPBP1 interacting checkpoint and replication regulator 
 cfa-u.3   TICRR   TOPBP1 interacting checkpoint and replication regulator 
 gga-u.3   TICRR   TOPBP1 interacting checkpoint and replication regulator 
 dre-u.3   ticrr   TopBP1-interacting, checkpoint, and replication regulator 
 cel-u.3   tres-1   TRESlin (TRESLIN) homolog 

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Top 50 coexpressed genes to Ticrr (mmu-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mmu3460   Fanconi anemia pathway  6 50 6.46
 mmu3440   Homologous recombination  5 37 7.14
 mmu4110   Cell cycle  4 122 3.35
 mmu3410   Base excision repair  2 32 2.40
 mmu1524   Platinum drug resistance  2 80 -

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mmu:Ticrr (TOPBP1-interacting checkpoint and replication regulator) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

mmu-u.4
for
Ticrr
mmu-r.6
for
Ticrr
mmu-m.5
for
Ticrr
rno-u.3
for
Ticrr
hsa-u.4
for
TICRR
mcc-u.3
for
TICRR
cfa-u.3
for
TICRR
gga-u.3
for
TICRR
dre-u.3
for
ticrr
cel-u.3
for
tres-1
1 Mybl2 myeloblastosis oncogene-like 2 17865 0 12.0 8.9
 7.0
 5.0
2.0
 7.9
2.6
 6.4
3.5
 2.8
1.7
 5.1
4.8
 4.9
2.8
2 Clspn claspin 269582 0 11.2 11.0
 5.0
 3.9
 6.3
 4.8
 1.4
 5.8
 7.9
 1.7
3 Exo1 exonuclease 1 26909 0 10.9 11.2
 4.6
 5.9
 10.0
 5.5
 3.1
 5.5
 4.8
 0.8
4 Orc1 origin recognition complex, subunit 1 18392 0 10.9 7.1
 6.9
 2.6
 9.2
 5.1
 3.6
 4.7
 4.1
 1.5
5 Foxm1 forkhead box M1 14235 0 10.3 9.8
 4.7
 3.2
 8.6
 8.4
 2.4
 5.4
-0.2
 5.4
6 Kif18b kinesin family member 18B 70218 0 10.3 11.6
 3.7
 6.8
4.8
 10.0
5.5
 9.6
3.9
 1.4
0.4
 5.8
5.7
 6.4
0.5
 0.6
7 Dtl denticleless E3 ubiquitin protein ligase 76843 0 10.2 10.2
 4.4
 5.3
 8.5
 5.9
 1.8
 6.3
 5.2
 1.9
8 Bard1 BRCA1 associated RING domain 1 12021 0 10.1 8.0
 5.5
 5.6
3.5
 1.7
 5.0
 3.5
9 Brca1 breast cancer 1, early onset 12189 0 10.0 10.0
 4.4
 5.5
 5.6
 4.0
 1.6
 6.4

10 Kif14 kinesin family member 14 381293 0 9.8 9.3
 4.5
 6.7
 7.4
 6.5
 2.0
 4.4
 6.7
11 Troap trophinin associated protein 78733 0 9.6 8.9
 4.6
 4.4
 7.4
 7.7

7.0
12 Ercc6l excision repair cross-complementing rodent repair deficiency complementation group 6 like 236930 0 9.5 10.3
 3.6
 5.2
 6.5
 4.1
 1.6
 6.2
 3.9
13 Cdca5 cell division cycle associated 5 67849 0 9.4 11.8
 2.7
8.6
 7.6

3.9
14 Hrob homologous recombination factor with OB-fold 217216 0 9.4 7.0
 5.5

3.3
 2.8
2.1
15 Kif4 kinesin family member 4 16571 0 9.3 8.4
 4.6
 4.0
 8.3
 6.6
 1.7
 8.0
 6.5
 1.8
16 Pole polymerase (DNA directed), epsilon 18973 0 9.3 10.2
 3.5
 7.3
 4.4
 5.2
 2.0
 5.7
 6.9
 0.9
17 Aunip aurora kinase A and ninein interacting protein 69885 0 9.2 7.6
 4.9
 4.2
 5.8
 3.0
 2.4
5.8
18 Dlgap5 DLG associated protein 5 218977 0 9.2 9.2
 4.0
 5.1
 6.5
 6.6
 2.2
 5.0
 5.5
 2.3
19 Brip1 BRCA1 interacting protein C-terminal helicase 1 237911 0 9.0 8.1
 4.5
 5.1
3.8
 1.7
 2.5
 4.3
 1.6
20 Mms22l MMS22-like, DNA repair protein 212377 0 9.0 7.8
 4.6
 5.0
 3.4
 2.9
 1.2
 4.2
 3.3
21 Sgo1 shugoshin 1 72415 0 8.9 9.6
 3.5
 5.8
 6.3
 3.9
 1.2
 5.5
 6.1
22 Cdca2 cell division cycle associated 2 108912 0 8.9 8.9
 3.9
 5.5
 9.7
 7.7
 2.2
 5.1
 4.4
23 Iqgap3 IQ motif containing GTPase activating protein 3 404710 0 8.9 8.9
 3.8
 4.8
1.2
 7.5
2.1
 5.3
1.1
 3.4
0.9
 4.0
1.1
 7.4
1.6
 -0.3
24 Rad54l RAD54 like (S. cerevisiae) 19366 0 8.8 8.3
 4.2
 4.6
 8.4
 7.5
 2.3
 4.3
 4.2
 -0.1
25 Lrr1 leucine rich repeat protein 1 69706 0 8.8 9.0
 3.7
2.2
 2.0
2.0
 1.1
 1.8
26 Mcm10 minichromosome maintenance 10 replication initiation factor 70024 0 8.7 7.3
 4.6
 4.1
 10.8
 5.2
 1.8
 4.7
 5.7
 2.1
27 Mis18bp1 MIS18 binding protein 1 217653 0 8.6 9.2
 3.4
 2.9
 1.8
 1.3
 1.6
 4.4
 5.8
28 Neil3 nei like 3 (E. coli) 234258 0 8.5 9.3
 3.3
7.0
 5.1
3.3
 4.1
29 Prr11 proline rich 11 270906 0 8.5 8.1
 3.9
 5.7
 4.7
 6.4
 1.6
 4.6
 5.3
30 Fanci Fanconi anemia, complementation group I 208836 1 8.5 8.1
 3.9
 3.7
 8.8
 3.3
 5.6
 6.3
 5.7
 3.8
31 Kntc1 kinetochore associated 1 208628 0 8.4 9.9
 2.8
 5.8
 3.9
 6.3
 1.7
 3.8
 5.7
 1.9
32 Kif2c kinesin family member 2C 73804 0 8.3 8.2
 3.6
 4.7
-1.1
 8.2
-0.2
 7.1
0.6
 1.6
1.1
 6.8
1.6
 1.3
-0.8
 0.7
33 Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 18140 0 8.2 11.1
 1.9
 4.7
 6.3
 5.7
 1.7
 4.7
 4.5
34 Stil Scl/Tal1 interrupting locus 20460 0 8.2 10.5
 2.2
 7.5
 7.3
 2.7
 2.9
 5.0
 8.5
35 Gtse1 G two S phase expressed protein 1 29870 0 8.1 6.8
 4.3
 3.8
 9.2
 7.2
 1.9
 5.6
 4.9
36 Top2a topoisomerase (DNA) II alpha 21973 0 8.1 10.3
 2.2
 5.5
-0.9
 6.6
0.1
 6.8
-0.2
 2.3
-0.5
 6.6
0.2
 4.8
0.5
 2.1
1.7
37 Chaf1a chromatin assembly factor 1, subunit A (p150) 27221 0 8.0 8.0
3.4
 5.6
 4.6
 3.3
 4.6
 5.7
 2.9
38 Cdc45 cell division cycle 45 12544 2 7.9 6.9
 4.1
 4.1
 8.1
 5.1
 3.0
 4.7
 6.2
 4.3
39 Espl1 extra spindle pole bodies 1, separase 105988 0 7.8 8.7
 2.9
 5.1
 9.6
 4.3
 2.4
 6.5
 7.8
 1.4
0.6
40 Ankle1 ankyrin repeat and LEM domain containing 1 234396 0 7.8 7.3
 3.6
 4.2
 0.7
 0.8
 1.8
 3.5
 2.4
 1.6
41 Fanca Fanconi anemia, complementation group A 14087 0 7.8 6.4
 4.2
 3.7
 7.3
 2.4
 2.1
 5.4
 3.3
42 Ttk Ttk protein kinase 22137 0 7.7 9.7
 2.3
 5.2
 7.3
 6.2
 1.9
 6.8
 4.8
43 Tedc1 tubulin epsilon and delta complex 1 104732 0 7.7 5.8
 4.4
 1.9
 0.5
 0.1
 0.7
 2.2
 0.1
44 Eme1 essential meiotic structure-specific endonuclease 1 268465 0 7.6 7.0
 3.7
 -0.6
 6.5
-0.8
 2.4
0.0
 2.7
-0.5
 4.4
-0.7
 4.1
45 Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 71988 0 7.6 10.2
 1.8
 5.3
-0.5
 8.3
0.8
 6.6
-0.9
 1.2
-0.7
 5.2
0.1
 2.8
2.0
 0.7
46 Fancd2 Fanconi anemia, complementation group D2 211651 0 7.6 6.5
 3.9
 4.7
 4.8
 2.9
 2.2
 4.4
 4.5
 0.3
47 Pask PAS domain containing serine/threonine kinase 269224 0 7.5 6.6
 3.8
 3.6
 2.4
 0.7
 1.3
 5.5
 4.9
48 Pif1 PIF1 5'-to-3' DNA helicase 208084 0 7.5 6.3
 3.9
5.8
 4.8
 2.9
 2.8
 3.2
 -0.2
49 Recql4 RecQ protein-like 4 79456 1 7.4 4.0
 5.2
 4.7
 5.0
 4.6
 1.7
 4.2
 5.2
50 Rad51ap1 RAD51 associated protein 1 19362 0 7.3 8.0
 2.7
 2.5
 5.5
 5.3
 2.7
 -0.9
 4.8
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