Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   hsd17b7   hydroxysteroid (17-beta) dehydrogenase 7 
 dre-r.3   hsd17b7   hydroxysteroid (17-beta) dehydrogenase 7 
 hsa-u.4   HSD17B7   hydroxysteroid 17-beta dehydrogenase 7 
 mmu-u.4   Hsd17b7   hydroxysteroid (17-beta) dehydrogenase 7 
 rno-u.3   Hsd17b7   hydroxysteroid (17-beta) dehydrogenase 7 
 gga-u.3   HSD17B7   hydroxysteroid 17-beta dehydrogenase 7 
 mcc-u.3   720399   3-keto-steroid reductase 
 cfa-u.3   HSD17B7   hydroxysteroid 17-beta dehydrogenase 7 
 sce-u.3   ERG27   3-keto-steroid reductase 

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Top 50 coexpressed genes to hsd17b7 (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre100   Steroid biosynthesis  11 20 6.82
 dre900   Terpenoid backbone biosynthesis  8 21 6.73
 dre3320   PPAR signaling pathway  5 84 5.71
 dre1240   Biosynthesis of cofactors  5 179 4.12
 dre1212   Fatty acid metabolism  4 73 4.51

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dre:hsd17b7 (hydroxysteroid (17-beta) dehydrogenase 7) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
hsd17b7
dre-r.3
for
hsd17b7
hsa-u.4
for
HSD17B7
mmu-u.4
for
Hsd17b7
rno-u.3
for
Hsd17b7
gga-u.3
for
HSD17B7
mcc-u.3
for
720399
cfa-u.3
for
HSD17B7
sce-u.3
for
ERG27
1 lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 795400 15.2 7.9
 10.1
 15.9
 14.2
 14.8
 3.2
 8.5
 5.8
2 msmo1 methylsterol monooxygenase 1 406662 14.5 7.5
 13.1
 16.6
 16.8
 15.7
 6.8
 7.6
2.3
 3.9
3 cyp51 cytochrome P450, family 51 414331 12.8 6.6
 6.5
 16.0
 14.9
8.5
 6.7
 3.5
4 sqlea squalene epoxidase a 799528 12.7 6.6
 10.7
 14.3
 14.4
 15.9
 7.0
 7.2
 4.1
5 sc5d sterol-C5-desaturase 447891 12.5 6.5
 8.5
 13.6
 13.6
 9.0
 3.1
 6.1
 5.3
6 ebp EBP cholestenol delta-isomerase 436600 12.4 6.4
 8.6
 4.3
 8.6
 10.4
 6.5
 5.0
7 hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 394060 12.1 6.3
 14.1
-0.0
 14.7
-0.2
 14.6
-1.8
 9.3
0.8
 6.6
-0.6
 9.3
1.0
 5.8
8 nsdhl NAD(P) dependent steroid dehydrogenase-like 550369 10.9 5.6
 11.8
 13.9
 12.9
 13.1
 7.2
 8.1
 9.3
9 hmgcra 3-hydroxy-3-methylglutaryl-CoA reductase a 559054 10.3 5.3
 12.9
 13.8
 12.3
 12.1
 2.0
 7.3
 3.6
0.2
10 fdps farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) 552997 10.2 5.3
 13.8
 13.0
 13.5
 12.9
 2.8
 7.8
 6.0
11 mvda mevalonate (diphospho) decarboxylase a 492781 9.9 5.2
 12.9
 12.3
8.6
 5.1
 4.7
 5.6
12 tm7sf2 transmembrane 7 superfamily member 2 494054 9.5 5.0
 11.3
5.0
 9.3
8.8
 11.1
10.5
 12.8
1.7
 5.6
2.4
 6.1
4.7
 4.1
3.8
13 dhcr24 24-dehydrocholesterol reductase 494102 8.8 4.6
 8.9
 11.4
 11.5
 14.1
 3.8
 5.5
14 tmem97 transmembrane protein 97 569147 8.3 4.3
 8.0
 6.5
 9.3
 0.1
 4.0
 2.8
 4.9
15 insig1 insulin induced gene 1 334189 8.0 4.2
 10.3
1.4
 10.3
1.2
 10.5
-0.8
 12.6
1.4
 3.8
1.1
 6.3
16 fdft1 farnesyl-diphosphate farnesyltransferase 1 571911 7.9 4.1
 12.4
 12.5
 13.1
 15.3
 5.9
 7.8
 6.8
17 scarb2a scavenger receptor class B, member 2a 192340 7.8 4.0
 -0.8
 -0.4
 -0.4
 0.6
 0.0
 0.3
18 fads2 fatty acid desaturase 2 140615 7.5 3.9
 7.5
7.0
 6.0
4.9
 5.2
4.1
 4.9
4.3
 3.4
1.8
 5.3
2.9
19 ebpl EBP like 768138 7.5 3.9
 0.7
 1.7
 2.2
1.3
 0.0
20 acat2 acetyl-CoA acetyltransferase 2 30643 7.1 3.7
 13.1
 10.4
1.0
 14.6
1.5
 6.9
6.1
21 dhcr7 7-dehydrocholesterol reductase 378446 7.0 3.7
 11.3
5.0
 9.3
8.8
 11.1
10.5
 12.8
1.7
 5.6
2.4
 6.1
4.7
 4.1
3.8
22 mvk mevalonate kinase 492477 6.9 3.6
 12.7
 11.3
 10.7
 8.9
 3.5
 5.5
 5.9
23 srebf2 sterol regulatory element binding transcription factor 2 100037309 6.8 3.6
 8.9
2.8
 9.5
2.1
 7.8
1.1
 11.1
4.2
 2.6
0.5
 1.6
 -0.2
-1.5
24 idi1 isopentenyl-diphosphate delta isomerase 1 553513 6.2 3.3
 11.4
 15.8
 14.9
 15.7
 8.3
1.1
 6.0
 2.8
25 ldlrb low density lipoprotein receptor b 393460 6.2 3.3
 9.7
4.4
 14.0
3.6
 9.2
2.9
 8.7
1.3
 5.1
1.2
 3.5
3.2
26 pcsk9 proprotein convertase subtilisin/kexin type 9 100150316 5.9 3.1
 4.8
 4.7
 6.3
 0.2
 0.9
1.2
0.4
27 sigmar1 sigma non-opioid intracellular receptor 1 393952 5.9 3.1
 0.2
 3.7
 3.9
 0.9
 1.4
 2.9
 7.5
28 erg28 ergosterol biosynthesis 28 homolog 565132 5.8 3.0
 9.1
 9.7
 8.1
 8.8
 4.5
 5.4
 5.1
29 cyb5r2 cytochrome b5 reductase 2 751641 5.7 3.0
 -0.1
-0.8
 1.1
-1.6
 1.8
0.5
 1.5
1.4
 0.0
-0.4
 2.0
0.3
 1.3
30 aacs acetoacetyl-CoA synthetase 393984 5.6 2.9
 4.4
 8.7
 10.0
 10.4
 2.7
 3.7
31 elovl2 ELOVL fatty acid elongase 2 678614 5.5 2.9
 5.4
1.4
 4.7
4.0
 3.1
1.5
 1.4
1.3
 1.8
1.3
 2.1
1.9
32 rdh12 retinol dehydrogenase 12 436597 5.2 2.7
 6.2
1.0
 8.9
0.6
 4.2
0.4
 7.1
1.1
 3.8
0.9
 4.7
1.4
 0.7
33 spra sepiapterin reductase a 554136 5.0 2.6
 0.8
 0.4
 -0.3
 1.9
 0.4
 1.0
34 pmvk phosphomevalonate kinase 100003383 4.8 2.5
 1.8
 8.4
 7.4
 5.6
 0.6
 1.3
35 alad aminolevulinate dehydratase 550338 4.5 2.4
 0.2
 0.2
 2.2
 2.4
 1.0
 0.8
 1.8
36 abcg4b ATP-binding cassette, sub-family G (WHITE), member 4b 794238 4.4 2.3
 -0.1
-0.7
 1.1
-0.1
 1.4
0.2
 1.3
-0.1
 0.8
-0.7
 0.1
-0.3
 0.1
37 igfbp2a insulin-like growth factor binding protein 2a 794176 4.3 2.3
 -0.1
 0.5
 0.0
 -0.6
 0.4
 -0.1
38 cyp8b3 cytochrome P450, family 8, subfamily B, polypeptide 3 447848 4.3 2.3
 -0.3
 1.3
 0.9
0.1
 0.4
39 nadsyn1 NAD synthetase 1 798974 4.1 2.2
 2.3
 0.5
 1.1
 1.7
 1.0
 1.8
 0.7
40 adck5 aarF domain containing kinase 5 100001584 4.1 2.2
 0.1
 -0.7
 -0.4
-1.2
 1.0
41 si:ch211-113j14.1 si:ch211-113j14.1 558239 4.1 2.1
 0.3
-0.1
 -0.3
 0.8
 -0.6
-0.8
 0.2
-0.2
 0.6
-0.2
42 aclya ATP citrate lyase a 436922 3.9 2.1
 6.5
 5.4
 7.0
 4.8
 3.0
 5.4
43 cyp8b2 cytochrome P450, family 8, subfamily B, polypeptide 2 100004274 3.9 2.1
 -0.3
 1.3
 0.9
0.1
 0.4
44 gmppaa GDP-mannose pyrophosphorylase Aa 431743 3.8 2.0
 1.8
 -0.8
 0.6
 1.9
 0.5
 1.0
45 elovl5 ELOVL fatty acid elongase 5 393425 3.8 2.0
 5.4
1.4
 4.7
4.0
 3.1
1.5
 1.4
1.3
 1.8
1.3
 2.1
1.9
46 ciao2a cytosolic iron-sulfur assembly component 2A 406300 3.8 2.0
 0.8
 -1.1
 -0.2
 0.5
 0.6
 0.5
47 acp6 acid phosphatase 6, lysophosphatidic 558758 3.7 2.0
 1.9
 -0.4
 -0.1
 0.6
 1.2
 0.0
48 lipg lipase, endothelial 393096 3.6 1.9
 4.6
 4.1
 2.3
 4.7
 2.2
 2.4
49 pmt phosphoethanolamine methyltransferase 767699 3.5 1.9






50 grtp1a growth hormone regulated TBC protein 1a 406711 3.5 1.8






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