Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   foxo1a   forkhead box O1 a 
 dre-r.3   foxo1a   forkhead box O1 a 
 dre-u.3   foxo1b   forkhead box O1 b 
 hsa-u.4   FOXO1   forkhead box O1 
 mmu-u.4   Foxo1   forkhead box O1 
 rno-u.3   Foxo1   forkhead box O1 
 gga-u.3   FOXO1   forkhead box O1 
 mcc-u.3   FOXO1   forkhead box O1 
 cfa-u.3   FOXO1   forkhead box O1 

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Top 50 coexpressed genes to foxo1a (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre4910   Insulin signaling pathway  5 171 4.21
 dre4068   FoxO signaling pathway  2 181 -
 dre4150   mTOR signaling pathway  2 206 -
 dre4020   Calcium signaling pathway  2 377 -
 dre4010   MAPK signaling pathway  3 409 -

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dre:foxo1a (forkhead box O1 a) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
foxo1a
dre-r.3
for
foxo1a
dre-u.3
for
foxo1b
hsa-u.4
for
FOXO1
mmu-u.4
for
Foxo1
rno-u.3
for
Foxo1
gga-u.3
for
FOXO1
mcc-u.3
for
FOXO1
cfa-u.3
for
FOXO1
1 hbp1 HMG-box transcription factor 1 554137 5.7 3.0
 0.9
 2.0
 1.8
 1.5
 1.7
 3.1
 1.0
2 pptc7a protein phosphatase targeting COQ7 a 492506 5.5 2.9
 2.1
1.2
 2.5
 4.6
 1.3
 2.6
 0.2
 3.8
3 rnf19b ring finger protein 19B 562396 5.3 2.8
 4.7
 0.5
 -0.7
 -0.9
 0.1
 -0.6
 1.2
4 socs2 suppressor of cytokine signaling 2 562062 5.1 2.7
 1.1
 1.4
 1.6
 -0.0
 1.2
 -0.3
 1.7
5 wbp1lb WW domain binding protein 1-like b 553658 5.0 2.6
 3.0
 1.2
 3.2
 2.8
 2.5
 1.9
 0.0
6 phka2 phosphorylase kinase, alpha 2 (liver) 556199 4.6 2.4
 1.7
1.5
 0.4
0.2
 0.8
 -0.1
-0.3
 0.2
0.1
 1.5
1.1
 -1.0
-1.1
7 dennd4a DENN/MADD domain containing 4A 558211 4.6 2.4
 1.8
 1.3
-0.7
 -0.0
-0.2
 -0.6
-0.7
 0.8
0.2
 1.0
0.2
 2.0
0.4
8 deptor DEP domain containing MTOR-interacting protein 768177 4.5 2.4
 0.4
 0.2
 2.3
 3.3
 0.2
 -0.5
 -0.3
9 arhgap46b Rho GTPase activating protein 46b 568268 4.4 2.3
 1.2
0.6
 0.1
 -0.1
 -0.7
 -1.9
-2.2
 -0.2
 -0.5
10 slc41a1 solute carrier family 41 member 1 325975 4.2 2.2
 1.6
0.2
 2.2
-0.4
 2.8
-0.3
 0.5
-0.4
 1.6
-0.6
 1.6
1.2
 1.6
0.3
11 loxl2a lysyl oxidase-like 2a 565508 4.1 2.2
 1.9
1.4
 0.1
-0.8
 0.3
0.0
 1.8
1.0
 1.0
0.7
 0.1
-0.5
 0.5
-0.1
12 ralgds ral guanine nucleotide dissociation stimulator 799483 4.0 2.1
 2.0
1.6
 0.0
-0.1
 0.4
0.1
 0.8
-0.9
 0.6
-0.6
 0.9
-0.0
 0.3
-0.2
13 crema cAMP responsive element modulator a 555432 4.0 2.1
 4.0
0.4
 0.6
-0.1
 0.5
-0.0
 0.3
0.0
 1.2
0.4
 1.6
0.3
 1.8
-0.1
14 furina furin (paired basic amino acid cleaving enzyme) a 566557 4.0 2.1
 1.1
1.0
 2.1
1.6
 2.2
1.7
 2.4
1.2
 1.5
1.2
 0.2
-0.4
 0.7
0.4
15 klf13 Kruppel-like factor 13 767805 3.9 2.1
 2.4
2.0
 2.5
 5.9
 6.9
 2.3
 2.7
 2.1
16 foxo1b forkhead box O1 b 567969 3.9 2.1
 3.9





17 insrb insulin receptor b 245700 3.9 2.1
 2.5
2.0
 2.2
2.0
 2.6
0.9
 1.6
0.9
 2.1
2.0
 2.0
1.5
 0.6
18 nr1i2 nuclear receptor subfamily 1, group I, member 2 565875 3.8 2.0
 0.9
 -0.4
 1.6
 1.5
-0.6
19 kiaa0355 KIAA0355 ortholog 100535053 3.8 2.0






20 slc27a6 solute carrier family 27 member 6 568835 3.8 2.0
 1.8
1.1
 0.5
0.3
 0.9
0.8
 1.4
-1.1
 1.1
0.8
 2.0
0.4
 1.9
1.4
21 slc12a7b solute carrier family 12 member 7b 567667 3.8 2.0
 1.4
0.8
 0.9
0.7
 1.5
1.3
 1.2
0.5
 1.3
0.9
 0.8
0.7
 1.1
0.8
22 rela v-rel avian reticuloendotheliosis viral oncogene homolog A 415099 3.8 2.0
 2.0
1.1
 1.7
0.8
 2.0
1.3
 3.3
1.2
 0.4
-0.6
 1.2
0.9
 2.7
1.5
23 slc35g1 solute carrier family 35 member G1 100001920 3.8 2.0
 1.8
1.1
 2.3
0.4
 0.1
24 tefb TEF transcription factor, PAR bZIP family member b 553686 3.7 2.0
 2.1
1.8
 1.0
 2.3
1.6
 1.6
-0.1
 2.0
0.1
 0.3
-0.4
 1.0
25 slc16a5a solute carrier family 16 member 5a 565514 3.7 2.0
 2.1
1.7
 1.7
0.7
 0.6
0.6
 1.3
0.6
 2.0
1.3
 0.5
0.3
 1.2
1.0
26 sox5 SRY-box transcription factor 5 567413 3.7 2.0
 1.1
0.6
 0.1
 0.3
-0.4
 -0.1
-1.1
 1.1
0.8
 -0.4
-1.2
 2.6
0.8
27 klf12b Kruppel-like factor 12b 100126139 3.7 2.0
 1.9
 2.1
 -0.3
 0.7
 -0.1
 0.9
 1.7
28 upp1 uridine phosphorylase 1 503707 3.7 2.0
 0.9
-0.7
 0.4
 0.1
 0.7
-0.2
 2.4
0.9
 -0.7
 -0.4
29 nedd4a NEDD4 E3 ubiquitin protein ligase a 619412 3.7 1.9
 1.5
0.7
 1.1
-0.4
 3.2
2.8
 2.9
2.2
 1.2
0.4
 3.1
1.3
 1.9
1.6
30 acer2 alkaline ceramidase 2 100331179 3.6 1.9
 1.3
-1.2
1.6
-0.2
 0.4
 -0.8
-0.9
0.4
31 rbms3 RNA binding motif, single stranded interacting protein 767747 3.6 1.9
 3.0
2.0
 1.2
0.5
 1.6
1.3
 0.8
0.2
 0.5
0.4
 1.5
1.0
 0.5
0.3
32 gpr155a G protein-coupled receptor 155a 100535239 3.6 1.9
 1.1
-1.1
 0.5
 2.0
 1.1
 0.7
 0.4
 0.4
33 wnk1b WNK lysine deficient protein kinase 1b 561159 3.6 1.9
 1.7
 1.5
 1.6
 3.7
 1.3
 2.6
 2.4
34 mef2d myocyte enhancer factor 2d 30580 3.5 1.9
 2.8
1.9
 2.8
1.7
 3.8
1.2
 4.6
2.9
 3.4
3.2
 2.1
0.6
 2.3
1.3
35 keap1a kelch-like ECH-associated protein 1a 321837 3.5 1.9






36 ssh2b slingshot protein phosphatase 2b 557912 3.5 1.9
 1.5
0.9
4.0
 0.8
 0.1
2.2
37 prkar1ab protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b 550427 3.5 1.9
 2.4
0.4
 0.5
0.1
 0.7
-1.4
 -0.6
-1.4
 0.7
-0.0
 0.4
-0.2
 1.0
-1.8
38 si:dkey-18a10.3 si:dkey-18a10.3 792628 3.5 1.9
 0.7
0.6
 0.3
-0.1
 0.4
-0.4
 0.2
-0.1
 1.0
0.6
 0.7
-0.8
 0.7
-0.5
39 abhd5a abhydrolase domain containing 5a 566493 3.5 1.9
 1.9
1.1
 1.2
-0.7
 1.4
-0.1
 1.0
-0.2
 3.2
 0.9
0.7
 -0.0
-0.3
40 pnpla2 patatin-like phospholipase domain containing 2 101887155 3.5 1.9
 1.4
0.1
 3.0
 3.1
 1.2
 2.1
-0.3
 1.7
 1.3
41 clpxb caseinolytic mitochondrial matrix peptidase chaperone subunit Xb 100332309 3.5 1.8
 1.2
0.7
 0.5
 -0.1
 1.0
0.6
 0.7
42 pdk4 pyruvate dehydrogenase kinase, isozyme 4 561007 3.5 1.8
 0.0
-0.4
 3.7
1.1
 2.6
2.3
 1.7
1.0
 2.0
1.4
 2.0
1.9
 2.1
0.9
43 epg5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 569543 3.5 1.8
 1.8
 -0.7
 -0.0
 1.0
 -0.1
 -0.7
 0.6
44 cpeb3 cytoplasmic polyadenylation element binding protein 3 100005268 3.5 1.8
 2.7
1.6
 0.7
 0.9
0.6
 1.4
1.2
 1.9
1.4
 1.1
-0.7
 1.7
0.5
45 tpra1 transmembrane protein, adipocyte asscociated 1 570573 3.4 1.8
 1.5
 -0.0
 0.5
 1.3
 -0.2
 -1.0
 1.6
46 pdgfrb platelet-derived growth factor receptor, beta polypeptide 559529 3.4 1.8
 0.4
 -1.2
 -1.1
 1.1
 -0.3
 0.1
 -0.6
47 lzts2b leucine zipper, putative tumor suppressor 2b 100005471 3.4 1.8
 2.3
1.5
 -0.8
 -0.6
 -1.0
 -1.7
 0.5
 -0.4
48 klhl24a kelch-like family member 24a 768198 3.4 1.8
 1.7
-0.8
 3.0
 1.0
 -0.2
 2.8
 1.0
 0.9
49 si:ch73-63e15.2 si:ch73-63e15.2 100002292 3.4 1.8
 0.6
-0.1
 1.0
0.2
 -0.8
 -0.3
-0.3
 1.8
-0.8
 1.0
0.9
 2.5
0.5
50 abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 100002010
1.8
0.8
 1.2
-0.1
 0.8
0.4
 1.5
1.0
 1.3
1.1
 1.5
1.5
 0.8
0.2
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