Orthologous genes in OrthoFinder**

Species Gene Description
 mcc-u.3   GBA   glucosylceramidase beta 
 mcc-r.3   GBA   glucosylceramidase beta 
 mcc-m.4   GBA   glucosylceramidase beta 
 hsa-u.4   GBA   glucosylceramidase beta 
 mmu-u.4   Gba   glucosidase, beta, acid 
 rno-u.3   Gba   glucosylceramidase beta 
 cfa-u.3   GBA   glucosylceramidase beta 
 gga-u.3   107050229   glucosylceramidase-like 
 gga-u.3   121112067   lysosomal acid glucosylceramidase-like 
 dre-u.3   gba   glucosidase, beta, acid 
 dme-u.3   Gba1b   Glucocerebrosidase 1b 
 dme-u.3   Gba1a   Glucocerebrosidase 1a 
 cel-u.3   gba-1   Putative glucosylceramidase 1 
 cel-u.3   gba-3   Putative glucosylceramidase 3 
 cel-u.3   gba-2   Putative glucosylceramidase 2 

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Top 50 coexpressed genes to GBA (mcc-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mcc4142   Lysosome  14 128 6.93
 mcc4141   Protein processing in endoplasmic reticulum  10 161 6.25
 mcc600   Sphingolipid metabolism  5 39 6.93
 mcc4140   Autophagy - animal  4 134 3.13
 mcc4145   Phagosome  4 154 2.90

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mcc:GBA (glucosylceramidase beta) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

mcc-u.3
for
GBA
mcc-r.3
for
GBA
mcc-m.4
for
GBA
hsa-u.4
for
GBA
mmu-u.4
for
Gba
rno-u.3
for
Gba
cfa-u.3
for
GBA
gga-u.3
for
107050229
gga-u.3
for
121112067
dre-u.3
for
gba
dme-u.3
for
Gba1b
dme-u.3
for
Gba1a
cel-u.3
for
gba-1
cel-u.3
for
gba-3
cel-u.3
for
gba-2
1 ATP6AP1 ATPase H+ transporting accessory protein 1 106995374 7.6 4.0
8.3
 9.0
 7.3
0.1
 4.6
 1.2
0.5
 -1.2
-1.5
 3.2
1.0
 1.6
-0.6
 -0.4
-0.5
 0.5
 -1.6
 0.4
2 LOC114677344 metaxin-1-like 114677344 7.5 3.9
5.7
-1.5
 2.1
-1.6
 2.1
-0.3
 3.5
-1.1
 -1.4
 0.0
 2.5
1.1
 -0.8
 -0.2
 -0.8
 0.5
 0.6
3 CTSA cathepsin A 708592 EGK_02341 7.1 3.7
 3.6
 13.6
 12.2
 7.6
 10.6
 3.9
 -0.5
 3.7
3.3

4.8
3.4
 3.2
1.1
 2.6
1.7
4 OS9 OS9 endoplasmic reticulum lectin 715555 6.9 3.6
5.9
 5.5
 5.5
 5.3
 6.5
 -0.4
 1.3




5 NCSTN nicastrin 719696 6.5 3.3
 3.4
 8.5
 5.6
 5.0
 2.9
 4.2
 -1.3
 1.0
 -0.5
 0.3
 -0.8
 -0.5
 -0.6
6 MFSD5 major facilitator superfamily domain containing 5 702021 EGK_03704 5.8 2.0
 4.3
 5.2
 5.2
 4.6
 4.6
 2.7
 -0.4
 3.3

2.1
 -0.9
 -0.1
7 CTSB cathepsin B 100424758 5.6 2.9
4.4
 6.4
 6.3
 3.6
 2.8
 -0.0
 1.5
0.8
 1.3
 0.8
 4.6
3.0
 0.2
-0.4
 1.6
1.2
8 GLMP glycosylated lysosomal membrane protein 719468 5.5 3.2
 2.5
 13.6
 13.9
 5.7
 11.5
 6.1
 0.5
 3.9




9 GRN granulin precursor 714851 5.5 2.9
8.5
 8.3
 7.2
 7.7

3.0
2.6

2.2
 1.6
 1.1
10 HEXA hexosaminidase subunit alpha 698251 EGK_17654 5.4 3.6
 1.7
 6.9
5.7
 5.5
5.2
 6.1
3.7
 7.1
4.7
 5.0
1.5
 -0.1
-1.8
 2.4
1.8
 0.4
0.3
 1.6
-0.6
 1.5
 1.3
 0.1
11 SLC35F6 solute carrier family 35 member F6 697195 EGK_05140 5.4 2.9
 2.7
 5.9
 6.0
 5.2
 3.7
 1.8
 -1.5
 3.7
 1.1
 0.5
 -1.2
 -0.9
 0.7
12 EDEM2 ER degradation enhancing alpha-mannosidase like protein 2 706150 EGK_02472 5.3 2.4
 3.2
 3.7
 3.3
 2.2
 2.6
 1.3
 -1.5
 1.8
 -0.1
 -0.3
 -0.7
 0.3
 -0.4
13 GANAB glucosidase II alpha subunit 718672 EGK_06108 5.2 2.8
4.4
 3.0
0.1
 4.3
0.8
 2.9
1.0
 -1.5
 0.0
 1.8
0.5
 -0.9
 0.9
 0.7
0.6
 1.1
-0.4
 -0.9
-0.9
14 GLB1 galactosidase beta 1 709355 5.2 2.7
6.6
3.9
 6.7
1.0
 6.9
3.1
 4.7
2.5
 2.5
0.9
 -0.8
-1.8
 3.3
2.5
 1.6
0.9
 2.2
0.2
 -0.2
 4.7
 -0.2
15 PIGS phosphatidylinositol glycan anchor biosynthesis class S 709115 5.1 2.7
4.6
 4.2
 7.0
 4.0
 4.2
 0.3
 1.5
 -0.2
 0.9
 -0.7
 1.1
 -0.2
16 C4H6orf89 chromosome 4 C6orf89 homolog 719165 5.0 2.7
4.2
 4.3
 1.7
 3.1
 0.7
 -1.7
 3.4




17 HM13 histocompatibility minor 13 713216 EGK_02537 5.0 2.6
 2.6
 4.3
 2.4
 1.9
 3.0
 1.5
 -0.8
 0.4
 -0.0
 0.3
 -1.4
 0.5
 -0.2
18 PLBD2 phospholipase B domain containing 2 714669 5.0 2.6
4.2
 4.5
 5.8
 5.8
 6.5
 -1.2
 2.2

1.2
0.9
 6.9
0.2
 1.1
-0.0
19 PSAP prosaposin 709510 4.9 2.6
5.4
-0.6
 4.3
0.4
 7.3
 5.3
 2.4
1.3
 2.5
-0.2
 1.6
 1.3
 0.8
 5.3
1.4
 5.8
1.8
 1.6
-1.0
20 TCTA T cell leukemia translocation altered 706633 EGK_11637 4.9 2.0
 3.2
 5.1
 2.2
 1.9
 2.3
 0.2
 -1.3
 0.4




21 SMPD1 sphingomyelin phosphodiesterase 1 711248 4.9 1.9
 3.3
 6.8
2.7
 5.0
2.5
 2.3
1.6
 4.0
1.5
 4.8
2.4
 -0.2
-0.4
 3.6
1.8
 1.5
1.5
 10.6
6.4
 3.0
2.9
 4.7
1.3
 2.9
2.4
22 TPP1 tripeptidyl peptidase 1 709838 4.8 4.5
 -0.1
 8.7
 7.5
 7.4
 7.2
 4.5
 -0.6
 2.8




23 LAMP1 lysosomal associated membrane protein 1 697331 4.8 2.5
7.4
5.5
 5.8
5.8
 5.7
4.2
 6.3
5.7
 1.7
0.7
 0.4
-1.2
 1.7
1.5
 0.5
 -0.1
 4.7
0.3
 0.8
0.7
 1.2
-0.2
24 SLC39A1 solute carrier family 39 member 1 715994 4.8 2.5
4.1
1.8
 3.2
1.6
 2.9
1.8
 2.2
0.9
 2.5
 0.1
 3.1
2.8
 -0.1
-0.8
 1.3
-0.0
 2.0
0.7
 1.7
1.4
 0.5
0.3
25 PIGT phosphatidylinositol glycan anchor biosynthesis class T 710556 4.7 2.3
 2.6
 6.3
 2.8
 5.1
 4.7
 2.8
 0.2
 0.4
 -1.6
 -1.0
 -0.9
 1.1
 0.0
26 ATP6V0D1 ATPase H+ transporting V0 subunit d1 698345 EGK_12894 4.7 2.5
7.5
1.1
 6.8
0.5
 6.8
0.5
 7.7
0.8
 3.7
1.2
 -0.5
-2.3
 2.5
 0.1
-1.4
 -0.1
-0.2
 -0.3
 -0.1
 -0.3
27 NEU1 neuraminidase 1 716740 EGK_14733 4.6 2.6
 2.1
 6.7
 5.5
 4.2
 2.2

2.2




28 RAB8A RAB8A, member RAS oncogene family 100423251 EGK_10269 4.6 2.5
2.7
1.2
 2.8
0.2
 2.7
2.6
 2.0
0.8
 0.5
-0.4
 1.0
0.5
 1.8
1.2
 0.2
-0.2
 -0.3
-0.4
 -0.7
-1.1
 1.4
-0.3
 -0.3
-0.5
29 G6PD glucose-6-phosphate dehydrogenase 701137 4.6 1.8
 3.2
 3.3
 2.6
 3.1
 3.4

2.5
 -0.2
-0.4
 0.8
0.0
 -0.6
 -0.2
 -0.2
30 TGOLN2 trans-golgi network protein 2 100426141 4.6 2.4
3.8
 3.9
 3.0
 2.3
 2.5
 -1.7
 3.0




31 NUDT18 nudix hydrolase 18 707061 4.5 1.5
 3.5
 1.4
 2.2
 2.9
 1.6
 2.7
 1.2
 0.7
 -0.4
 -0.6
 -0.5
 1.0
 -1.3
32 GLA galactosidase alpha 703129 EGK_20744 4.5 2.1
 2.7
 4.7
4.4
 7.4
5.2
 6.1
4.5
 3.7
2.4
 4.6
4.4
 -0.1
-1.4
 3.0
2.1
 1.9
-0.7
 0.7
-0.7
 0.7
 5.0
 -0.5
33 DNAJB12 DnaJ heat shock protein family (Hsp40) member B12 721891 EGK_19744 4.5 2.4
3.6
-1.3
 1.8
1.3
 2.5
2.5
 2.2
2.2
 2.5
-0.3
 0.2
-0.4
 0.3
0.1
 -0.1
 0.1
 -1.2
 -0.2
 0.6
34 BCAP31 B cell receptor associated protein 31 696663 4.5 2.0
 2.8
 4.1
0.8
 5.6
-0.9
 4.3
-0.2
 3.3
-1.7
 6.0
1.4
 0.1
-0.1
 1.6
0.3
 -0.7
 0.2
 1.5
 -0.2
 0.1
35 RPN2 ribophorin II 708971 4.5 2.8
 1.7
 4.7
 5.9
 3.2
 4.2
 2.3
 -1.0
 1.7
 -0.1
 0.8
 -0.2
 -0.1
 0.0
36 PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 714283 4.5 2.4
 2.3
 4.1
3.5
 3.7
3.3
 3.7
2.2
 2.8
0.6
 1.0
0.0
 -1.7
-1.8
 0.4
-0.2
 -0.8
 -0.8
 -1.0
 2.9
 0.1
37 GNS glucosamine (N-acetyl)-6-sulfatase 717500 4.4 2.8
 1.6
 7.5
 6.7
 5.3
 3.6
 3.0
 -2.2
 3.2
1.8
 -0.5
 -0.2


38 QSOX1 quiescin sulfhydryl oxidase 1 718589 4.4 2.0
 2.6
 4.4
-1.3
 2.1
0.5
 2.9
0.0
 1.9
-0.9
 5.0
1.1
 0.1
-0.8
 2.0
1.5
 2.0
0.6
 1.3
0.4
 0.9
0.6
 0.6
0.5
 0.9
-0.4
39 TMEM127 transmembrane protein 127 705069 EGK_05569 4.4 2.1
 2.6
 5.5
 3.1
 5.2
 2.7
 0.8
 0.4
 2.0




40 SEL1L SEL1L adaptor subunit of ERAD E3 ubiquitin ligase 708651 4.4 2.3
2.3
 3.3
 3.6
 2.5
 1.7
 -0.1
 2.2
 -0.4
 -0.3
 -0.3
 -0.2
 0.1
41 DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit 706148 4.4 2.3
3.7
 4.9
 4.3
 4.0
 2.7
 -1.0
 0.5
 -0.5
 0.2
 -0.2
 -0.2
 0.4
42 ZDHHC24 zinc finger DHHC-type containing 24 713870 4.4 1.2
 3.7
 2.6
 2.3
 2.4
 3.4

-0.3

0.0
 -1.3
 -0.3
43 SCAMP2 secretory carrier membrane protein 2 709720 4.4 2.9
 1.4
 4.4
 3.9
 3.3
 1.0
 2.6
 -1.6
 1.2
0.7




44 P4HB prolyl 4-hydroxylase subunit beta 714702 4.4 2.0
 2.6
 3.5
2.2
 3.8
3.5
 2.2
1.9
 2.8
1.6
 2.3
1.2
 -0.0
-1.1
 2.4
1.3
 -0.2
-0.4
 0.8
0.4
 0.1
-0.3
 0.3
0.1
 -0.3
-0.7
45 CYBC1 cytochrome b-245 chaperone 1 716212 EGK_09132 4.4 1.7
 2.9
3.0
 3.3
 0.8
 0.9
 -1.5
 2.8




46 RER1 retention in endoplasmic reticulum sorting receptor 1 694540 EGK_00133 4.3 1.8
 2.9
 2.2
 3.3
 2.2
 0.7
 0.1
 -0.9
 1.0
 -0.6
 0.2
 -0.7
 -0.1
 -0.0
47 LAMP2 lysosomal associated membrane protein 2 695379 EGK_20887 4.3 2.2
 2.2
 7.4
5.5
 5.8
5.8
 5.7
4.2
 6.3
5.7
 1.7
0.7
 0.4
-1.2
 1.7
1.5
 0.5
 -0.1
 4.7
0.3
 0.8
0.7
 1.2
-0.2
48 PDIA6 protein disulfide isomerase family A member 6 706781 4.2 2.1
 2.3
 1.4
 2.4
 2.9
 1.9
 0.7
 -0.8
 1.3
 0.2
 0.5
 1.4
-0.5
 -0.1
-0.5
 0.8
0.3
49 GPR108 G protein-coupled receptor 108 703831 4.2 1.9
 2.6
 4.7
3.6
 4.6
4.2
 3.7
3.2
 4.5
0.5
 1.6
 0.7
 0.7
-1.0
 -1.2
 0.2
 -0.8
 1.1
 -0.6
50 SLC22A18 solute carrier family 22 member 18 721230 4.2 1.3
 3.3
 3.1
 0.6
 2.7
 1.2
 -1.5
 -0.5
 -0.1

2.1
 1.6
 0.4
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