Orthologous genes in OrthoFinder**

Species Gene Description
 mcc-u.3   NANS   N-acetylneuraminate synthase 
 mcc-r.3   NANS   N-acetylneuraminate synthase 
 mcc-m.4   NANS   N-acetylneuraminate synthase 
 hsa-u.4   NANS   N-acetylneuraminate synthase 
 mmu-u.4   Nans   N-acetylneuraminic acid synthase (sialic acid synthase) 
 rno-u.3   Nans   N-acetylneuraminate synthase 
 cfa-u.3   NANS   N-acetylneuraminate synthase 
 dre-u.3   nansb   N-acetylneuraminic acid synthase b 
 dre-u.3   nansa   N-acetylneuraminic acid synthase a 
 dme-u.3   NANS   N-acetylneuraminic acid synthase 

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Top 50 coexpressed genes to NANS (mcc-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mcc5014   Amyotrophic lateral sclerosis  9 331 6.20
 mcc5010   Alzheimer disease  9 342 6.08
 mcc5022   Pathways of neurodegeneration - multiple diseases  9 426 5.30
 mcc5012   Parkinson disease  8 237 6.25
 mcc5016   Huntington disease  8 277 5.74

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mcc:NANS (N-acetylneuraminate synthase) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

mcc-u.3
for
NANS
mcc-r.3
for
NANS
mcc-m.4
for
NANS
hsa-u.4
for
NANS
mmu-u.4
for
Nans
rno-u.3
for
Nans
cfa-u.3
for
NANS
dre-u.3
for
nansb
dre-u.3
for
nansa
dme-u.3
for
NANS
1 XBP1 X-box binding protein 1 713863 5.8 2.2
 4.0
 6.2
 3.6
 3.4
 2.9
 0.1
 2.9
 -0.9
2 MANF mesencephalic astrocyte derived neurotrophic factor 700659 5.7 2.6
 3.4
 6.3
 7.3
 5.9
 5.1
 0.0
-0.5
 5.1
0.3
 -0.0
3 POLE4 DNA polymerase epsilon 4, accessory subunit 710562 5.7 3.0
1.9
 1.8
 -0.7
 1.0
 -0.6
 0.9
 -1.2
4 PRELID1 PRELI domain containing 1 699254 EGK_17190 5.5 2.3
 3.6
 3.4
 3.9
 2.5
 2.8
 0.8
-0.8
 0.5
-0.1
 -1.1
5 PDIA4 protein disulfide isomerase family A member 4 709716 5.5 2.5
 3.3
 4.5
 5.3
 6.6
 4.8
 -0.5
 5.8
6 SDF2L1 stromal cell derived factor 2 like 1 697928 5.5 2.4
 3.4
 6.2
2.4
 8.7
1.8
 5.0
2.2
 8.3
0.5
 0.1
-0.0
 4.8
2.1
 -0.6
7 PDCL3 phosducin like 3 715243 5.3 2.8
1.6
 1.2
0.0
 0.1
0.1
 -1.1
 -0.9
 1.3
 0.2
8 PDIA6 protein disulfide isomerase family A member 6 706781 5.2 2.3
 3.2
 3.2
 6.2
 7.2
 5.7
 -0.7
 4.9
 -0.5
9 PPIB peptidylprolyl isomerase B 706757 5.2 3.3
 1.8
 4.6
1.4
 5.7
0.5
 6.0
-0.0
 6.6
0.3
 1.0
0.3
 3.3
0.8
 -0.2
10 PHB prohibitin 699334 5.1 3.0
 2.1
 1.4
 1.4
 2.2
 0.8
 -0.3
 4.2
 0.2
11 HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 700018 EGK_20527 5.0 2.6
1.6
 0.3
 0.7
 1.6
 -0.8
 2.7
 -0.5
12 CLTA clathrin light chain A 693659 4.9 2.5
 2.5
 4.5
 3.2
2.0
 1.8
0.6
 4.8
2.0
 1.5
0.4
 5.3
0.6
 -1.2
13 LAGE3 L antigen family member 3 700924 4.8 2.6
1.3
 1.4
 2.6
-0.6
 -0.2
14 AKR1A1 aldo-keto reductase family 1 member A1 693380 EGK_00701 4.8 2.6
 2.4
 5.2
0.5
 2.9
2.3
 5.2
2.6
 2.0
1.0
 2.4
0.9
 3.3
0.8
 0.9
0.9
15 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 699482 4.8 2.3
 2.7
 5.8
 5.3
 5.6
 4.8
 -0.1
 4.4
 0.0
16 NDUFB11 NADH:ubiquinone oxidoreductase subunit B11 705984 4.8 2.5
1.5
 0.1
 -0.2
 0.2
 -0.2
 1.4
 -0.4
17 MLEC malectin 697934 EGK_04270 4.7 1.8
 3.3
 3.4
 4.8
 4.1
 1.1
 1.6
 2.7
 -0.7
18 AHSA1 activator of HSP90 ATPase activity 1 706547 EGK_18420 4.6 1.8
 3.1
 4.0
 2.6
2.0
 1.2
1.2
 1.1
 -0.0
-0.2
 1.6
0.3
 -0.7
19 JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase 720764 EGK_09020 4.6 2.4
3.3
 1.2
 0.9
 1.9
 2.2
 -0.8
 -1.4
20 PSMA7 proteasome 20S subunit alpha 7 720175 4.5 2.5
 2.2
 1.8
 2.2
 1.3
 1.4
 -0.3
 2.4
 -0.2
-0.8
21 GMPPB GDP-mannose pyrophosphorylase B 705454 4.5 2.2
 2.6
 5.6
 6.1
 6.9
 5.8
 0.8
 4.4
 -0.3
22 AK2 adenylate kinase 2 709737 4.5 2.5
 2.1
 1.6
 1.0
 2.3
 1.8
 0.5
 -0.3
 -0.5
23 ETHE1 ETHE1 persulfide dioxygenase 718089 EGK_10692 4.5 2.4
 2.3
 2.3
 2.3
 -0.6
 1.2
 0.8
 -0.7
 -0.7
24 MRPS21 mitochondrial ribosomal protein S21 706805 EGK_01225 4.4 2.4
-0.4
 0.8
 1.3
 2.3
 0.2
 1.6
 0.2
25 RNASEH2C ribonuclease H2 subunit C 700330 4.4 2.3
0.4
 2.0
 1.8
 2.7
 -0.5
 0.6
 0.7
26 SNF8 SNF8 subunit of ESCRT-II 700029 4.4 2.4
 2.1
 3.4
 1.9
 1.7
 1.0
 -1.1
 1.6
 -0.4
27 FKBP4 FKBP prolyl isomerase 4 708481 4.4 1.9
 2.7
 2.5
 2.1
 2.1
 2.9
 1.3
 1.2
 0.7
28 RABAC1 Rab acceptor 1 706397 EGK_10668 4.4 2.3
 2.2
 3.2
 0.7
 -0.3
 2.5
 0.2
 1.4
 0.3
29 CCT7 chaperonin containing TCP1 subunit 7 706157 4.3 2.4
 2.0
 3.3
 2.6
 2.4
 2.4
0.5
 -0.7
 1.1
 -0.3
30 SEC61A1 SEC61 translocon subunit alpha 1 709787 4.3 1.4
 3.3
 4.7
-1.6
 6.4
-1.1
 8.3
-1.6
 5.1
-0.7
 0.3
-0.8
 3.0
0.4
 -0.0
31 ATP5MC1 ATP synthase membrane subunit c locus 1 697950 4.3 2.6
 1.9
 2.1
1.3
 2.5
-0.2
 1.5
-0.3
 1.8
1.4
 0.5
-0.6
 5.0
2.1
 -0.9
32 FAM50A family with sequence similarity 50 member A 106995375 4.3 2.3
2.2
 2.4
 1.3
 0.7
 -1.5
 1.4
 0.1
33 SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 715183 4.3 2.3
0.7
 3.8
 2.0
 0.6
 0.5
 -0.2
 -0.1
34 COPE COPI coat complex subunit epsilon 719631 4.3 2.3
5.0
 5.7
 6.3
 4.4
 0.9
 4.2
 0.2
35 CDK4 cyclin dependent kinase 4 715650 EGK_03854 4.2 1.4
 3.2
 0.4
-0.1
 1.3
0.5
 1.2
-0.3
 -0.0
-0.3
 0.9
-0.1
 0.7
-1.4
 0.6
36 TUBA1B tubulin alpha 1b 709643 4.2 2.2
1.8
1.8
 2.8
2.5
 3.1
3.0
 1.5
0.9
 1.3
1.1
 3.2
2.2
 1.0
0.2
37 TBCB tubulin folding cofactor B 712355 4.1 2.2
0.2
 5.4
 3.2
 1.9
 0.0
 2.6
 0.3
38 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 703628 EGK_18852 4.1 2.2
3.5
0.2
 1.0
0.1
 1.3
-0.2
 3.2
-2.1
 0.4
0.2
 1.9
-0.8
 -1.3
39 MCTS1 MCTS1 re-initiation and release factor 696543 4.1 2.0
 2.4
 2.1
 0.2
-1.0
 2.1
0.1
 1.3
0.5
 -0.5
 3.6
 -1.6
40 TNIP2 TNFAIP3 interacting protein 2 722308 4.1 1.5
 2.9
 1.1
 0.0
 -1.7
 1.1
 -1.3
 -0.4
41 PSMB3 proteasome 20S subunit beta 3 694318 4.0 2.2
2.4
 2.3
 2.7
 2.4
 -0.5
 3.7
 -0.9
42 CD63 CD63 molecule 709828 EGK_03768 4.0 1.8
 2.6
 2.7
 0.6
 1.2
 2.4
 -1.8
 1.2
 0.2
-0.8
43 PSMD8 proteasome 26S subunit, non-ATPase 8 721897 4.0 2.5
 1.6
 2.7
 1.7
 1.3
 0.9
 -0.1
 5.1
 -0.5
-1.2
44 SHMT2 serine hydroxymethyltransferase 2 714433 EGK_03829 4.0 1.4
 3.0
 1.4
0.2
 1.2
0.1
 1.5
-0.1
 1.3
1.0
 0.5
-0.7
 2.8
0.5
 0.6
45 AHSA2P activator of HSP90 ATPase homolog 2, pseudogene 719540 EGK_05362 4.0 1.9
 2.3
 4.0
 2.6
2.0
 1.2
1.2
 1.1
 -0.0
-0.2
 1.6
0.3
 -0.7
46 TRIM27 tripartite motif containing 27 706129 EGK_14629 4.0 1.9
 2.3
 2.8
0.9
 3.2
0.8
 3.1
-0.0
 2.9
1.2
 2.8
2.7
 0.9
0.9
47 MRPS15 mitochondrial ribosomal protein S15 713412 4.0 2.1
1.7
 1.7
 0.9
 1.0
 -1.1
 2.0
 0.3
48 SEC13 SEC13 homolog, nuclear pore and COPII coat complex component 697339 EGK_11422 3.9 1.4
 2.8
 5.5
 4.2
 5.6
 6.1
 0.7
 5.9
 -0.2
49 NDUFA11 NADH:ubiquinone oxidoreductase subunit A11 697843 3.9 2.1
3.1
 1.3
 1.0
 1.0
 -0.5
 1.1
 0.6
50 SEC61B SEC61 translocon subunit beta 717815 3.9 1.9
 2.3
 7.0
 7.7
 6.4
 9.3
 -0.1
 1.9
 0.6
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