Orthologous genes in OrthoFinder**

Species Gene Description
 cfa-m.4   CDKL4   cyclin dependent kinase like 4 
 cfa-u.3   CDKL1   cyclin dependent kinase like 1 
 hsa-u.4   CDKL1   cyclin dependent kinase like 1 
 mmu-u.4   Cdkl1   cyclin-dependent kinase-like 1 (CDC2-related kinase) 
 mmu-u.4   Cdkl4   cyclin-dependent kinase-like 4 
 rno-u.3   Cdkl4   cyclin-dependent kinase-like 4 
 rno-u.3   Cdkl1   cyclin dependent kinase like 1 
 mcc-u.3   CDKL1   cyclin dependent kinase like 1 
 gga-u.3   CDKL1   cyclin dependent kinase like 1 
 dre-u.3   cdkl1   cyclin-dependent kinase-like 1 (CDC2-related kinase) 
 dme-u.3   CG7236   uncharacterized protein 
 cel-u.3   cdkl-1   Cyclin-dependent kinase-like 1;Protein kinase domain-containing protein 

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Top 50 coexpressed genes to CDKL4 (cfa-m.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 cfa630   Glyoxylate and dicarboxylate metabolism  2 33 -
 cfa71   Fatty acid degradation  1 43 -
 cfa330   Arginine and proline metabolism  1 49 -
 cfa4976   Bile secretion  2 73 -
 cfa190   Oxidative phosphorylation  1 169 -

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cfa:CDKL4 (cyclin dependent kinase like 4) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

cfa-m.4
for
CDKL4
cfa-u.3
for
CDKL1
hsa-u.4
for
CDKL1
mmu-u.4
for
Cdkl1
mmu-u.4
for
Cdkl4
rno-u.3
for
Cdkl4
rno-u.3
for
Cdkl1
mcc-u.3
for
CDKL1
gga-u.3
for
CDKL1
dre-u.3
for
cdkl1
dme-u.3
for
CG7236
cel-u.3
for
cdkl-1
1 ANKRD45 ankyrin repeat domain 45 611232 3.7

2.4
 3.0



3.0

2 DRC1 dynein regulatory complex subunit 1 475690 3.6 0.1
 1.2
 1.2
 5.3
 2.3
 0.9
 1.0
 2.7
 2.8
 -0.9
3 LOC483842 centrin-4 483842 3.3 0.8
-0.3
 0.4
 1.9
1.0
 2.6
0.7
 2.5
1.2
 0.6
-0.5
 2.4
-1.1
 0.9
-0.2
 1.8
0.8
 -0.6
-1.2
 -0.2
4 CDH16 cadherin 16 489770 3.2 1.9
 1.8
 1.8
 0.3
 -0.9
 0.4
 -0.2



5 FANK1 fibronectin type III and ankyrin repeat domains 1 611459 3.1 0.1
1.9
 6.4
 2.4
 0.0

0.5

6 CCDC148 coiled-coil domain containing 148 478758 3.1 0.5





1.8


7 IFT22 intraflagellar transport 22 479727 3.1 0.0
 -0.0
 1.5
 0.5
 2.3
 1.3
 1.1
 1.7
 1.5
4.9
8 ODAD3 outer dynein arm docking complex subunit 3 476706 3.0

1.2
 3.9
 2.2
 0.2
 -0.9
4.5

9 TSPAN1 tetraspanin 1 475370 2.9










10 MUC1 mucin 1, cell surface associated 448784 2.8 -0.0
 -0.2
 -1.0
 0.5
 -0.0
 -0.3
 1.3



11 SPATA17 spermatogenesis associated 17 608327 2.7 0.4
 0.7



-0.0
 2.6
 2.6

12 LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 486930 2.7 0.2
-1.5
 -0.3

-0.5
 -0.1
 -0.7
0.6
13 DYNLRB2 dynein light chain roadblock-type 2 479636 2.7 0.9
-0.6
 0.3
0.1
 0.9
-1.1
 4.5
0.4
 2.4
0.6
 0.5
-1.7
 1.2
0.3
 1.5
-0.3
 1.3
-0.5
 1.0
-0.4
 -0.7
14 NEK11 NIMA related kinase 11 485660 2.7 1.1
 2.0



0.2
 3.1
 1.9

15 CCDC198 coiled-coil domain containing 198 611129 2.7

1.7
 -0.5
 -1.1
 -0.5
1.0


16 EFCAB10 EF-hand calcium binding domain 10 609764 2.6



1.5
 -0.1
2.1
 1.9

17 FAM81A family with sequence similarity 81 member A 478326 2.6 0.7
 2.9
 2.5
 2.5
 0.8
 -0.1
 1.7
 2.2


18 SULT1D1 sulfotransferase family, cytosolic, 1D, member 1 403637 2.6 1.3
1.0
 0.8
0.7
 1.2
1.0
 2.1
1.4
 1.5
1.3
 0.3
0.3
 0.7
0.5
 0.7
0.3
 1.7
1.4
 1.2
0.8
 0.6
19 CYP4A37 cytochrome P450 4A37 482506 2.6 1.7
1.7
 2.1
0.7
 3.4
2.0
 2.8
1.4
 1.8
0.6
 1.2
1.1
 1.5
0.6
 1.4
0.5
 1.4
0.3
 1.2
1.2
 1.4
1.1
20 FXYD2 FXYD domain containing ion transport regulator 2 608594 2.5










21 CFAP69 cilia and flagella associated protein 69 609727 2.5

2.1
 2.2
 2.7
 -0.0
 0.8
 1.7


22 PIH1D2 PIH1 domain containing 2 479440 2.5
1.3
 1.3
 5.1
 2.2
 0.8
 -0.1
 1.8
-0.3
23 PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein like 479214 2.5 1.4
0.7
 0.5
0.1
 2.3
0.5
 1.1
-0.2
 0.0
-0.1
 0.6
0.3
 0.5
-0.8
 0.1
 1.5
-0.3
0.8
0.1
24 CLTRN collectrin, amino acid transport regulator 611445 2.4 1.5
 -0.2
 1.5
 1.0
 -0.9
 0.3
 -0.7
 2.3
 1.0

25 SUGCT succinyl-CoA:glutarate-CoA transferase 483247 2.4 1.1
0.8
 0.4
 -0.3
 0.5
 0.5
 0.2
0.3
26 ARMH1 armadillo like helical domain containing 1 475383 2.4 -0.3





2.9
 2.5

27 DNAI4 dynein axonemal intermediate chain 4 479538 2.4 0.5
 1.3

2.1
 0.1
 1.5
 2.2


28 RIPPLY1 ripply transcriptional repressor 1 610288 2.3 0.1









29 DNAH7 dynein axonemal heavy chain 7 488452 2.3 1.2
0.9
 1.2
1.0
 2.0
1.8
 5.6
4.3
 2.7
1.8
 2.0
1.4
 1.7
1.3
 2.8
2.4
 3.5
3.1
 5.0
4.4
30 ITGB8 integrin subunit beta 8 475253 2.3 0.2
 -0.5
 -0.2
 -1.3
 -1.5
 -1.2
 0.4
 0.9
 1.8

31 DNAJB13 DnaJ heat shock protein family (Hsp40) member B13 476809 2.3

-0.5
 4.4
 3.0
 0.2
 1.5
 1.6
 3.7

32 HAO2 hydroxyacid oxidase 2 475814 2.3 2.7
 0.5
-0.5
 0.9
-0.6
 0.2
-0.2
 0.3
-1.0
 0.4
-0.2
 0.1
-0.1
 0.5
0.1
 0.5
0.4
 -0.4
 1.1
33 EFCAB1 EF-hand calcium binding domain 1 477872 2.3 -0.5
1.7
 3.9
 1.6
-0.7
 -0.3
-0.5
2.0
 2.9

34 ZMYND10 zinc finger MYND-type containing 10 476615 2.3 0.4
 0.6
 2.2
 4.4
 3.7
 0.6
 1.0
 2.4
 4.1
 0.8
35 MINAR1 membrane integral NOTCH2 associated receptor 1 610163 2.3
1.6
 1.3
 0.1
 0.5
 1.2
0.7
 0.2

36 MDH1B malate dehydrogenase 1B 478883 2.3
-0.5



1.4
 1.4
 1.5

37 ROPN1L rhophilin associated tail protein 1 like 478616 2.3
1.0
 0.1
 2.3
 2.1
 1.1
 2.5
 1.5
 3.1

38 OSCP1 organic solute carrier partner 1 475334 2.3 0.5
 -0.1
 1.6
 3.2
 2.8
 0.3
 0.8
 3.0
 0.9
 4.8
39 CFAP61 cilia and flagella associated protein 61 477136 2.2



2.7
 0.1
 1.6
 1.8
 2.0
 -0.7
-0.7
40 CCDC173 coiled-coil domain containing 173 478786 2.2 0.6
 0.4
 0.6
 2.3

0.1
 1.5
 3.2

41 CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 610385 2.2 1.7
1.7
 2.1
0.7
 3.4
2.0
 2.8
1.4
 1.8
0.6
 1.2
1.1
 1.5
0.6
 1.4
0.5
 1.4
0.3
 1.2
1.2
 1.4
1.1
42 HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 608755 2.2 1.6
 0.6
 0.0
 -0.9
 -0.5
 -0.6
-0.4
 1.0

43 ABCC2 ATP binding cassette subfamily C member 2 403632 2.2 1.1
1.1
 4.4
1.1
 0.6
0.1
 0.4
0.3
 0.4
0.2
 0.3
-0.1
 1.4
0.8
 1.3
0.9
 1.5
1.1
 0.3
0.1
 0.8
0.6
44 USH1C USH1 protein network component harmonin 610850 2.2 -0.4
 1.1
 1.3
 -1.5
 -0.5
 0.1
 0.4
 0.9
 -0.3
 0.5
45 TDRD5 tudor domain containing 5 480050 2.2



-1.0
 1.3
0.3
 0.2
 -0.1
 -0.0
46 LRRC46 leucine rich repeat containing 46 480539 2.2 -1.3
 -0.4
 0.5
 2.7
 2.5
 -0.0
 0.9
 3.7


47 TMC5 transmembrane channel like 5 489989 2.2 0.3
 1.7
 -0.2
 1.2
 0.8
 0.2
 -0.6
 0.7
 0.5

48 IQCA1 IQ motif containing with AAA domain 1 477415 2.2
-0.1
 1.7
 5.8
 1.7
 -0.4
 -0.6
 1.5
 1.8
1.6
 2.4
49 EFHC2 EF-hand domain containing 2 480888 2.2 0.2
-0.5
 1.0
0.7
 2.2
0.5
 3.7
2.9
 3.6
1.7
 2.4
1.0
 0.6
-0.4
 2.5
2.1
 4.8
3.2
 2.7
0.8
50 DCDC2 doublecortin domain containing 2 488244










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