Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3  nhsb  Nance-Horan syndrome b (congenital cataracts and dental anomalies) 
 dre-r.3  nhsb  Nance-Horan syndrome b (congenital cataracts and dental anomalies) 
 dre-u.3  nhsa  Nance-Horan syndrome a (congenital cataracts and dental anomalies) 
 hsa-u.4  NHS  NHS actin remodeling regulator 
 mmu-u.4  Nhs  NHS actin remodeling regulator 
 rno-u.3  Nhs  NHS actin remodeling regulator 
 gga-u.3  NHS  NHS actin remodeling regulator 
 mcc-u.3  NHS  NHS actin remodeling regulator 
 cfa-u.3  NHS  NHS actin remodeling regulator 

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Top 50 coexpressed genes to nhsb (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre4260   Cardiac muscle contraction  3 133 2.37
 dre4261   Adrenergic signaling in cardiomyocytes  3 244 -
 dre4810   Regulation of actin cytoskeleton  2 308 -
 dre4020   Calcium signaling pathway  1 377 -
 dre4010   MAPK signaling pathway  3 409 -

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dre:nhsb (Nance-Horan syndrome b (congenital cataracts and dental anomalies)) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID LINK Target Reference

dre-u.3
for
nhsb


dre-r.3
for
nhsb


dre-u.3
for
nhsa


hsa-u.4
for
NHS


mmu-u.4
for
Nhs


rno-u.3
for
Nhs


gga-u.3
for
NHS


mcc-u.3
for
NHS


cfa-u.3
for
NHS

1 adgrb2 adhesion G protein-coupled receptor B2 556993 5.5 2.9
1.3
1.1
0.8
-0.9
0.6
0.2
0.1
2 tenm2b teneurin transmembrane protein 2b 568845 5.2 2.7
3.9
2.8
2.9
0.9
3.4
1.8
2.2
1.5
2.1
1.8
2.0
1.2
2.3
0.5
3 fryb furry homolog b (Drosophila) 792949 5.1 2.7
1.3
1.1
0.3
0.2
0.7
-1.3
1.9
-0.5
2.4
1.4
-0.5
-0.6
1.3
-0.7
4 pcdh1a protocadherin 1a 100006496 4.9 2.6
1.6
1.1
0.1
0.7
0.3
0.9
-0.4
0.4
5 pcp4l1 Purkinje cell protein 4 like 1 100008021 4.8 2.5
0.8
0.5
0.1

0.3
0.4
-1.0
6 kiaa1549la KIAA1549-like a 566592 4.6 2.4
0.8
-0.6
1.4
0.9
-0.5
1.9
0.3
1.7
7 fmnl2b formin-like 2b 492608 4.6 2.4
3.8
2.1
2.1
0.8
2.3
0.5
1.8
1.0
-0.7
-0.8
1.5
0.3
-0.0
-1.3
8 dscaml1 DS cell adhesion molecule like 1 100002762 4.6 2.4
0.9
-0.2
0.7
0.3
-0.7
0.1
-0.7
0.7
-1.2
0.5
-0.5
0.8
9 ccdc88aa coiled-coil domain containing 88Aa 100329473 4.6 2.4
1.0
0.7
0.0
-0.3
1.1
3.2
2.7
1.7
-0.9
0.3
0.2
0.5
0.3
10 lmo1 LIM domain only 1 280646 4.6 2.4
0.8
0.2
0.7
0.7
1.1
-1.0
-1.1
1.2
0.5
1.6
-0.7
0.2
-0.2
11 mast1b microtubule associated serine/threonine kinase 1b 796144 4.5 2.4
2.1
1.7
0.5
0.2
-0.7
-0.9
0.3
-0.2
1.6
0.1
0.4
-1.2
1.1
-0.9
12 podxl2 podocalyxin-like 2 563754 4.4 2.3
-0.2
0.1
1.0
-0.1
1.6
0.7
-0.9
13 sptbn4a spectrin, beta, non-erythrocytic 4a 100003123 4.4 2.3







14 LOC103911884 uncharacterized LOC103911884 103911884 4.4 2.3







15 si:ch211-220f16.2 si:ch211-220f16.2 797650 4.3 2.3
1.2



1.3


16 zmiz2 zinc finger, MIZ-type containing 2 100333571 4.3 2.3
2.6
2.3
1.4
-0.1
0.3
-0.1
0.0
-0.6
1.1
-0.3
-0.4
-0.6
1.8
0.3
17 clasp1a cytoplasmic linker associated protein 1a 562077 4.3 2.3
1.6
1.3
0.2
0.1
1.0
0.7
1.7
-0.5
1.3
0.9
-0.5
-1.4
0.5
0.1
18 rapgef2a Rap guanine nucleotide exchange factor 2a 793952 4.2 2.2
2.6
2.5
0.5
-0.3
1.6
0.3
2.0
-0.7
1.4
0.5
1.4
-0.5
0.5
-0.8
19 syn1 synapsin I 570672 4.2 2.2
-0.9
-1.2
0.9
-0.4
0.7
-0.5
1.2
1.0
1.3
1.1
0.2
0.2
0.4
0.2
20 rfx7a regulatory factor X7a 560368 4.2 2.2
3.1
1.9
0.6
2.0
2.1
1.2
0.8
0.1
21 arhgap35b Rho GTPase activating protein 35b 564565 4.1 2.2
2.3
2.3
0.3
0.0
0.9
0.4
1.9
0.0
0.6
-0.6
0.9
0.1
0.5
0.2
22 rgs3b regulator of G protein signaling 3b 557360 4.1 2.2







23 apc APC regulator of WNT signaling pathway 386762 4.0 2.1
1.3
1.1
0.3
-0.3
1.4
0.4
2.4
-0.4
0.8
0.6
0.2
-1.4
1.3
0.9
24 cacng3b calcium channel, voltage-dependent, gamma subunit 3b 564883 4.0 2.1
-0.4
-0.4
-0.1
-1.7
0.4
-0.2
0.6
25 shisa7b shisa family member 7 100034520 4.0 2.1
-0.2
-0.4
0.3
0.2
0.5
-0.3
-0.1

26 cacna1fb calcium channel, voltage-dependent, L type, alpha 1F subunit 559964 4.0 2.1
2.6
2.0
1.6
1.4
1.9
0.9
1.8
1.7
1.8
0.8
1.0
0.7
1.9
1.8
27 lrrn3a leucine rich repeat neuronal 3a 101887059 3.9 2.1
1.2
0.6
0.7
0.3
1.2
-0.8
0.1
-0.2
0.6
0.3
0.4
0.3
-0.4
-0.6
28 pdzd2 PDZ domain containing 2 569088 3.9 2.1
1.0
0.6
2.6
0.9
1.6
0.8
1.1
29 si:ch211-170a17.1 si:ch211-170a17.1 101884914 3.9 2.1
-0.9
-2.0
0.8
1.3

0.7
0.6

30 cuedc1a CUE domain containing 1a 768297 3.8 2.0
1.2
-0.3
1.6
-0.6
0.5
-0.0
0.5
0.8
31 sdk2a sidekick cell adhesion molecule 2a 561852 3.8 2.0
2.2
0.7
1.1
2.6
1.8
1.7
1.6
3.2
-0.2
2.2
-0.4
1.7
-0.3
32 igsf21b immunoglobin superfamily, member 21b 567714 3.8 2.0







33 fam171b family with sequence similarity 171 member B 561242 3.8 2.0
-0.9
1.3
-0.5
0.4
0.6
1.4
-0.2
34 lrfn5a leucine rich repeat and fibronectin type III domain containing 5a 100144400 3.8 2.0
1.3
1.1
0.9
0.3
1.2
1.0
0.6
-0.7
0.6
0.5
3.2
1.3
1.9
0.2
35 lhx1a LIM homeobox 1a 30463 3.8 2.0
-1.7
-2.3
1.7
1.1
0.8
0.2
1.3
0.9
0.4
-1.0

36 zgc:109889 zgc:109889 553542 3.8 2.0
0.7
0.2
0.9
2.9
0.9
1.7
1.2
0.4
0.9
37 sall2 spalt-like transcription factor 2 568044 3.8 2.0







38 rnf157 ring finger protein 157 555415 3.7 2.0
0.6
0.7
0.1
0.6
0.2
0.4
0.1
0.7
-1.9
0.6
-0.9
0.8
-0.1
39 kdm2ba lysine (K)-specific demethylase 2Ba 406446 3.7 2.0
0.8
-0.4
-0.9
-1.1
0.8
-0.9
0.6
-0.2
1.5
0.9
-0.5
-1.2
-1.2
-1.6
40 map1aa microtubule-associated protein 1Aa 100151220 3.7 2.0
2.2
1.7
1.4
-0.4
1.6
1.1
2.1
0.7
1.0
0.6
1.8
1.1
1.1
0.7
41 LOC100537815 potassium voltage-gated channel subfamily A member 2 100537815 3.7 2.0
3.3
2.8
0.3
-0.6
2.3
2.1
2.1
1.6
0.8
0.5
0.5
0.2
-0.3
-0.7
42 amph amphiphysin 393804 3.7 2.0
1.8
-0.2
1.6
0.0
-0.3
-1.5
1.4
-0.5
-0.6
-2.7
-0.2
-1.1
1.1
0.4
43 zc4h2 zinc finger, C4H2 domain containing 323487 3.7 1.9
-0.1
-0.0
0.1
-0.3
0.1
1.5
-0.2
44 six3a SIX homeobox 3a 30635 3.7 1.9
1.5
1.0
0.4
-0.9
1.5
1.0
0.6
-0.1
-0.0

45 cbx6b chromobox homolog 6b 556231 3.6 1.9
0.1
-1.5
1.7
-0.2
-1.0
2.2
-0.6
2.4
46 znf800a zinc finger protein 800a 568719 3.6 1.9
0.5
0.4
-0.8
0.2
1.2
1.2
0.4
1.1
47 slain1a SLAIN motif family, member 1a 560157 3.6 1.9
0.3
-1.0
-0.5
1.0
0.4
0.7
0.2
48 nav1a neuron navigator 1a 100536287 3.6 1.9
2.5
1.7
2.1
1.1
2.3
2.3
0.6
0.6
1.5
0.4
2.0
1.6
2.8
2.0
49 atp1a3a ATPase Na+/K+ transporting subunit alpha 3a 64610 3.6 1.9
1.8
0.8
0.7
0.7
1.4
0.5
1.1
0.6
1.2
1.1
3.1
1.0
1.1
0.7
50 negr1 neuronal growth regulator 1 445374 3.6 1.9
1.7
1.6
1.4
1.2
0.1
-0.2
1.3
0.5
1.9
0.7
3.1
2.2
2.1
0.3
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