Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4  PIAS4  protein inhibitor of activated STAT 4 
 hsa-r.6  PIAS4  protein inhibitor of activated STAT 4 
 hsa-m.7  PIAS4  protein inhibitor of activated STAT 4 
 hsa-m2.4  PIAS4  protein inhibitor of activated STAT 4 
 hsa-u.4  PIAS3  protein inhibitor of activated STAT 3 
 hsa-u.4  PIAS2  protein inhibitor of activated STAT 2 
 hsa-u.4  PIAS1  protein inhibitor of activated STAT 1 
 mcc-u.3  PIAS4  protein inhibitor of activated STAT 4 
 mcc-u.3  PIAS3  protein inhibitor of activated STAT 3 
 mcc-u.3  PIAS2  protein inhibitor of activated STAT 2 
 mmu-u.4  Pias2  protein inhibitor of activated STAT 2 
 mmu-u.4  Pias1  protein inhibitor of activated STAT 1 
 mmu-u.4  Pias3  protein inhibitor of activated STAT 3 
 rno-u.3  Pias2  protein inhibitor of activated STAT, 2 
 rno-u.3  Pias3  protein inhibitor of activated STAT, 3 
 rno-u.3  Pias1  protein inhibitor of activated STAT, 1 
 cfa-u.3  PIAS2  protein inhibitor of activated STAT 2 
 cfa-u.3  PIAS3  protein inhibitor of activated STAT 3 
 cfa-u.3  PIAS1  protein inhibitor of activated STAT 1 
 gga-u.3  PIAS3  protein inhibitor of activated STAT 3 
 gga-u.3  PIAS2  protein inhibitor of activated STAT 2 
 gga-u.3  PIAS1  protein inhibitor of activated STAT 1 
 dre-u.3  pias1a  protein inhibitor of activated STAT, 1a 
 dre-u.3  pias1b  protein inhibitor of activated STAT, 1b 
 dre-u.3  pias4a  protein inhibitor of activated STAT, 4a 
 dme-u.3  Su(var)2-10  Suppressor of variegation 2-10 
 cel-u.3  gei-17  E3 SUMO-protein ligase gei-17 
 sce-u.3  NFI1  SUMO ligase NFI1 
 sce-u.3  SIZ1  SUMO ligase SIZ1 

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Top 50 coexpressed genes to PIAS4 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa3040   Spliceosome  3 127 2.18
 hsa4140   Autophagy - animal  2 141 -
 hsa4120   Ubiquitin mediated proteolysis  2 142 -
 hsa4530   Tight junction  2 169 -
 hsa5202   Transcriptional misregulation in cancer  3 192 -

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hsa:PIAS4 (protein inhibitor of activated STAT 4) External Links;


Show/Hide Columns:          
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID CoexPub LINK Target Reference

hsa-u.4
for
PIAS4


hsa-r.6
for
PIAS4


hsa-m.7
for
PIAS4


hsa-m2.4
for
PIAS4


hsa-u.4
for
PIAS3


hsa-u.4
for
PIAS2


hsa-u.4
for
PIAS1


mcc-u.3
for
PIAS4


mcc-u.3
for
PIAS3


mcc-u.3
for
PIAS2


mmu-u.4
for
Pias2


mmu-u.4
for
Pias1


mmu-u.4
for
Pias3


rno-u.3
for
Pias2


rno-u.3
for
Pias3


rno-u.3
for
Pias1


cfa-u.3
for
PIAS2


cfa-u.3
for
PIAS3


cfa-u.3
for
PIAS1


gga-u.3
for
PIAS3


gga-u.3
for
PIAS2


gga-u.3
for
PIAS1


dre-u.3
for
pias1a


dre-u.3
for
pias1b


dre-u.3
for
pias4a


dme-u.3
for
Su(var)2-10


cel-u.3
for
gei-17


sce-u.3
for
NFI1


sce-u.3
for
SIZ1

1 MED16 mediator complex subunit 16 10025 0 8.9 10.2
4.1
5.5
1.0
0.1
0.4
2.2
1.1
-0.9
0.2
1.0
1.6
1.6
0.8
0.2
-1.3
0.6
-0.6
0.4
1.8
0.8
2.5
1.0
2.9
1.0



2 DCAF15 DDB1 and CUL4 associated factor 15 90379 0 8.8 7.6
1.5
7.9
3.9
0.2
1.6
2.6
1.2
-0.7
-1.0
0.3
3.7
-1.2
4.0
0.4
-0.2
0.8
1.4
6.7
0.0
0.2
-0.1
-0.3
1.7
2.2



3 RANBP3 RAN binding protein 3 8498 0 8.8 9.8
2.7
5.6
0.8
0.3
1.1
-0.3
3.1
0.7
1.2
-2.2
1.4
-0.9
0.6
-1.0
-0.6
1.1
1.7
1.2
0.2
1.6
-0.0
1.9
1.0
0.5
-0.7
0.3
-1.6
2.1
0.4
0.3
-1.2
2.7
-1.4
2.0
0.2
2.8
1.6
2.9
2.2
3.6
1.2
0.8
0.9
-1.1
0.1
4 FZR1 fizzy and cell division cycle 20 related 1 51343 2 8.4 7.9
2.2
6.9
1.6
0.7
0.1
-0.3
0.8
-0.2
2.9
0.7
0.4
0.1
-0.8
1.6
-0.1
2.8
-0.0
0.3
-0.9
1.8
-0.4
0.8
0.0
0.7
-0.7
-0.2
-0.8
0.2
0.0
1.7
-0.7
2.3
0.2
1.6
-0.8
0.5
0.3
3.0
-0.3
0.7
-0.2
2.3
1.3
1.2
2.5
0.5
0.4
-0.6
5 SIRT6 sirtuin 6 51548 0 7.9 8.3
2.7
5.7
-1.0
-1.4
0.0
1.7
-0.2
-1.3
-0.1
-1.1
1.3
-1.2
2.1
-0.7
-1.9
0.6
-1.5
-0.0
1.1
-0.3
-0.2
1.2
0.9
0.2
-0.1


6 ADAT3 adenosine deaminase tRNA specific 3 113179 0 7.9 7.9
3.0
6.0
0.4
0.2
0.4



0.8
-1.4
-0.4
-0.6
-0.1
-1.6
0.8
-1.5
-0.2
2.6
-0.3
-1.0
0.0
1.2
1.2
0.4
-3.2
0.2
-0.4
7 MIER2 MIER family member 2 54531 0 7.9 8.4
2.2
5.5
2.7
0.2
0.7
-0.4
2.3
0.6
3.2
0.4
2.5
0.1
1.2
-0.4
1.3
0.2
3.4
1.4
2.0
1.7
2.8
0.6
1.4
1.0
3.6
2.4
0.7
-0.3
0.7
-0.3
2.5
0.9
0.9
0.8
3.2
2.5
2.5
0.3
3.0
2.9
5.0
4.9
2.2
1.6
1.5
2.7
2.1


8 SUGP1 SURP and G-patch domain containing 1 57794 0 7.9 6.3
3.2
7.5
1.1
-0.3
1.0
4.3
0.6
0.7
0.6
1.5
1.2
1.0
1.5
1.7
-0.3
0.5
0.4
1.4
2.0
0.5
0.4
0.8
1.3
-0.1



9 HDGFL2 HDGF like 2 84717 0 7.8 9.3
3.4
4.4
2.5
0.1
1.6
1.0
1.4
0.3
4.1
1.9
0.5
0.3
2.2
1.2
3.2
1.6
2.1
0.3
2.2
-0.1
1.9
1.7
1.5
0.7
2.3
1.7
2.1
-0.1
1.8
0.3
2.2
0.3
2.4
0.2
2.5
1.7
0.1
-1.0
-0.4
-1.2
-0.3
-1.2
3.3
-0.2
1.9
0.3
3.6


10 APBA3 amyloid beta precursor protein binding family A member 3 9546 0 7.7 8.5
3.1
5.1
0.0
-1.1
-0.5
3.4
0.8
-1.6
0.4
-1.5
-0.1
-0.2
1.0
-1.6
-2.4
-0.7
-0.3
2.5
-0.7
-2.2
0.3
1.1
1.7




11 SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha 6449 1 7.6 7.9
3.4
5.5
-0.0
-1.1
0.6
0.4
0.9
0.5
3.8
-0.9
2.8
-0.1
0.8
0.4
1.9
1.5
1.1
0.0
0.7
0.4
1.8
1.4
0.1
-0.9
0.8
-0.5
1.7
-1.1
-0.2
-0.8
1.2
-0.6
0.0
-0.8
1.4
0.4
0.8
-0.2
-0.1
-1.8
-1.5
-2.8
-0.1
-0.3
-0.2
0.3


12 MAP2K7 mitogen-activated protein kinase kinase 7 5609 0 7.5 9.6
2.4
3.6
0.3
-0.5
1.3
5.5
-0.8
0.0
1.1
1.4
2.5
0.8
1.7
1.0
-0.1
0.8
0.3
3.8
2.2
4.2
2.8
2.7
0.6
1.5
0.5


13 NELFA negative elongation factor complex member A 7469 0 7.5 8.3
2.8
4.9
1.3
-0.7
1.3
4.1
4.2
0.2
-0.1
1.7
1.4
-0.3
3.9
2.1
-0.6
1.9
1.4
0.6
1.0
2.6
0.8
2.1
3.4
2.7



14 SAFB scaffold attachment factor B 6294 0 7.4 8.7
4.8
4.3
0.0
-0.7
0.1
-0.3
1.0
1.0
4.4
3.6
-0.2
-0.2
-0.1
-0.3
-0.3
-0.7
0.1
-0.1
-0.1
-0.2
-0.1
-0.5
1.7
-0.7
2.9
1.7
0.2
-0.1
0.8
0.4
2.8
2.7
1.2
0.4
0.9
-0.2
0.7
0.6
0.7
-0.2
3.6
1.9



15 DAPK3 death associated protein kinase 3 1613 2 7.3 8.4
3.3
4.5
-0.7
-0.5
-1.0
1.5
0.6
0.3
0.0
-0.7
-1.0
-0.7
-0.2
-1.1
-2.0
0.9
-1.7
2.0
-0.0
-1.1
-1.6
0.3
-0.1




16 MAP1S microtubule associated protein 1S 55201 0 7.3 7.7
2.0
5.1
1.5
0.6
1.2
0.2
1.0
0.4
1.8
-0.1
2.2
0.3
1.4
0.5
-0.2
-0.4
1.1
-0.3
2.1
0.3
0.1
-0.6
1.2
0.4
-0.4
-0.6
1.3
0.9
2.2
1.0
1.1
0.4
1.6
-0.1
0.8
-0.2
-0.4
-0.8
-0.6
-0.7
-1.0
-1.4
0.7
0.4
-0.5



17 XAB2 XPA binding protein 2 56949 0 7.3 7.6
1.2
5.2
0.9
-1.0
2.6
2.5
1.0
-0.2
-0.7
3.6
1.4
-0.3
0.2
2.3
-2.5
-0.6
1.4
2.4
0.3
-0.7
-0.3
-0.6
1.1
-0.1
1.1
0.1
0.9
18 REXO1 RNA exonuclease 1 homolog 57455 0 7.0 6.9
0.6
5.4
0.3
0.7
-0.2
1.7
1.2
0.8
-0.4
0.2
-0.1
0.4
0.6
-0.5
-0.5
0.3
-0.8
-1.0
0.2
-0.8
1.2
-0.4
2.4
0.1
1.4
-0.8
1.6
-1.0
0.9
-1.6
-1.4
19 RBM42 RNA binding motif protein 42 79171 0 6.9 6.7
1.6
5.4
1.1
-1.3
0.6
5.1
0.9
-1.0
-1.8
0.7
0.7
-0.3
1.7
0.2
-1.9
0.5
0.8



0.7
0.7
3.5
0.8
0.2


20 PHRF1 PHD and ring finger domains 1 57661 0 6.8 7.0
1.8
5.0
-0.2
0.1
0.1
5.5
1.8
-0.3
-0.5
0.7
0.3
0.0
1.7
2.1
0.4
0.7
1.2
-1.3
-0.7
1.6
1.1
2.3
2.2
3.7



21 STK11 serine/threonine kinase 11 6794 0 6.7 7.0
3.8
4.8
-0.3
0.6
-1.2
2.1
-0.5
0.8
0.9
-0.4
0.0
1.8
-1.3
-0.5
-1.5
-1.5
-0.1
-0.9
0.1
1.5
-0.3
3.3
2.9
0.9
1.7


22 E4F1 E4F transcription factor 1 1877 0 6.7 5.8
1.9
5.9
0.6
-1.5
0.3
0.1
1.0
0.3
-1.1
1.9
2.6
-1.5
2.1
-0.3
-1.8
0.0
-0.4
-0.3
1.2
1.3
1.7
1.7
0.9




23 POLRMT RNA polymerase mitochondrial 5442 1 6.7 6.6
3.4
5.1
-0.0
0.7
-0.6
3.6
-1.5
0.3
0.8
-1.3
0.9
-1.5
1.0
-0.7
-0.4
-0.4
-0.4
0.5
2.0
0.3
1.1
1.8
-0.3
0.6
1.2
0.8
0.7
24 C19orf25 chromosome 19 open reading frame 25 148223 0 6.5 6.3
3.3
5.2
-0.6
-0.3
-0.5
4.3
-0.5
-1.5
-2.0
-0.7
1.3
-0.6
1.1
-1.7
-1.6
0.5
-0.8
1.9
-0.2
-1.8
-0.1
-1.2
-0.5




25 SF3A2 splicing factor 3a subunit 2 8175 0 6.5 7.3
1.9
4.1
0.9
-0.2
1.3
3.8
2.8
2.0
0.3
0.6
0.0
0.1
1.5
2.5
-1.0
1.4
0.5
0.8
1.2
-0.3
-0.5
0.3
2.9
1.7
-0.9
-0.2
0.9
26 CHERP calcium homeostasis endoplasmic reticulum protein 10523 0 6.4 6.4
2.0
4.8
1.2
0.3
1.0
4.1
3.0
-0.0
0.0
1.6
1.2
-0.4
3.0
1.1
-0.3
0.9
0.4
0.7
1.6
0.1
-0.4
1.7
4.3
4.9
-0.1


27 ZBTB45 zinc finger and BTB domain containing 45 84878 0 6.3 6.8
1.9
4.3
1.3
-0.5
1.2
2.2
1.2
-1.3
0.3
0.6
1.2
-1.1
2.7
1.8
-0.3
-0.3
0.2
0.5
-1.4
-0.9
1.0
0.4
1.1




28 MLLT1 MLLT1 super elongation complex subunit 4298 0 6.2 6.9
2.9
4.1
0.1
-0.4
0.9
0.1
3.0
0.8
2.3
-0.4
1.7
-0.6
1.1
-0.1
1.3
-1.7
0.7
1.8
1.0
0.6
-0.6
2.9
0.3
-0.2
-1.1
1.0
-0.3
1.9
-1.5
0.5
-0.1
1.2
0.7
-0.6
-1.0
0.6
0.3
0.4
-0.2
1.6
0.2
5.7



29 TBC1D10B TBC1 domain family member 10B 26000 0 6.2 6.3
1.1
4.6
2.1
-0.5
1.2
2.7
2.3
-2.1
0.3
0.6
4.0
-0.6
2.2
0.1
-1.1
2.1
2.0










30 SAFB2 scaffold attachment factor B2 9667 0 6.1 6.5
2.5
4.2
0.0
-0.7
0.1
-0.3
1.0
1.0
4.4
3.6
-0.2
-0.2
-0.1
-0.3
-0.3
-0.7
0.1
-0.1
-0.1
-0.2
-0.1
-0.5
1.7
-0.7
2.9
1.7
0.2
-0.1
0.8
0.4
2.8
2.7
1.2
0.4
0.9
-0.2
0.7
0.6
0.7
-0.2
3.6
1.9



31 CACTIN cactin, spliceosome C complex subunit 58509 0 6.0 6.2
2.9
4.4
-0.6
-0.7
-0.9
4.0
1.6
0.2
-0.2
-1.0
0.6
-1.2
1.9
0.6
-2.0
0.1
0.6
0.7
0.6
0.0
0.9
0.6
3.1
-0.5
-0.4


32 RAVER1 ribonucleoprotein, PTB binding 1 125950 0 6.0 6.6
1.6
4.0
2.4
1.1
0.9
4.7
3.0
-1.6
-0.3
0.3
1.8
-0.3
1.6
1.9
0.5
1.7
1.8
7.1
1.7
-0.1
1.6
2.0
-0.7




33 RFX1 regulatory factor X1 5989 0 6.0 7.3
2.5
3.2
1.7
1.0
1.7
-0.2
2.3
1.0
2.0
0.3
1.1
-0.0
3.1
0.4
0.7
0.5
2.8
1.7
1.9
1.8
0.3
-0.1
2.5
0.3
1.4
0.9
1.3
0.1
0.9
0.2
2.1
0.6
1.5
0.6
0.9
-0.1
1.1
0.4
2.8
2.5
2.5
2.4
1.2
1.1
2.0
2.7
2.4
2.8
34 ZNF282 zinc finger protein 282 8427 0 6.0 5.9
2.0
4.6
0.4
-0.8
-0.6
3.2
0.9
-1.5
-0.6
-0.6
1.4
-1.3
2.9
-0.4
1.4
1.3
-0.5










35 UPF1 UPF1 RNA helicase and ATPase 5976 0 5.9 5.8
3.0
4.5
-0.4
0.1
1.0
4.3
2.5
-1.0
0.2
0.2
0.6
2.1
0.3
1.3
-1.2
0.1
1.8
-1.3
1.2
1.2
1.7
2.4
2.7
0.7
1.8
0.2
-0.0
36 ZNF653 zinc finger protein 653 115950 0 5.8 7.0
3.4
3.2
-0.4
0.6
-0.6
2.2
0.1
-0.8
0.7
0.8
1.1
0.1
2.3
1.0
-1.3
-0.6
0.5



1.6
2.0
0.3




37 TIMM29 translocase of inner mitochondrial membrane 29 90580 0 5.8 6.1
2.5
4.1
-0.6
-0.6
-0.6
1.9
1.1
0.1
2.3
0.1
-0.2
1.3
-2.1
-0.9
-0.7
0.2
0.0
3.2
-0.3
-0.5
-0.4
0.1
1.0
0.5
-1.2


38 YJU2 YJU2 splicing factor homolog 55702 0 5.8 5.4
3.7
4.8
-0.6
-0.3
0.8
3.7
-0.3
0.3
-1.8
1.6
0.0
-2.1
-0.9
0.0
-0.5
-0.7
1.0
0.3
0.8
0.8
0.3
1.8
1.5
1.1
4.1
1.1
0.5
39 CTDP1 CTD phosphatase subunit 1 9150 0 5.8 6.4
2.6
3.8
-1.3
3.7
0.3
6.9
-0.3
-0.5
1.6
0.7
0.1
2.0
0.0
-0.2
-0.2
-0.3
-1.1
-0.1
-0.4
1.9
2.3
1.3
-0.3
0.5
1.4
1.0
0.7
40 SCAF1 SR-related CTD associated factor 1 58506 0 5.7 7.6
0.1
2.6
1.4
-0.4
0.5
2.5
0.5
-1.4
-0.3
0.1
2.3
-0.0
1.7
1.4
-0.8
1.1
0.1



0.2
1.0
3.5




41 FBXL19 F-box and leucine rich repeat protein 19 54620 0 5.7 6.4
2.4
3.6
1.0
-0.1
-1.1
2.8
-0.9
-1.3
-1.0
-1.5
0.9
-1.1
0.9
-0.1
-0.6
0.6
0.5



0.6
1.4
4.5




42 MBD3 methyl-CpG binding domain protein 3 53615 0 5.7 5.6
2.1
4.4
1.5
-2.0
3.1
0.9
0.8
-2.0
2.6
1.4
0.9
-0.8
1.2
-0.6
1.5
1.3
0.9
-1.8
-0.7
-0.8
3.6
2.5
0.4
-0.7
0.6
-1.1
0.3
-0.8
0.0
-1.0
0.9
-1.3
1.1
0.3
1.9
0.2
1.2
0.5
0.7
-1.0
1.6
-0.7
3.8
1.2
3.3



43 DOHH deoxyhypusine hydroxylase 83475 0 5.7 6.0
2.3
4.0
-1.2
-0.2
-2.3
4.1
0.0
-0.7
0.1
-1.4
-1.4
0.8
-1.5
-1.2
-1.2
-0.5
-2.3
1.0
-0.2
-1.7
-0.9
-1.2
-1.5
-0.4
0.7
0.8
0.1
44 RAB40C RAB40C, member RAS oncogene family 57799 0 5.6 5.1
2.7
4.8
1.4
-0.1
0.8
-0.4
0.5
-1.2
1.5
1.0
-1.0
0.3
-0.6
0.4
0.0
3.2
-0.1
1.4
-0.1
4.0
0.7
0.8
-0.1
-0.0
2.0
-0.4
1.2
-1.1
1.3
-0.6
0.3
0.3
0.4
-0.4
2.1
-0.6
1.4
-1.3
1.3



45 KEAP1 kelch like ECH associated protein 1 9817 0 5.6 5.8
2.9
4.1
0.0
0.3
-1.2
3.4
1.8
-3.1
-0.5
0.2
1.1
0.0
0.2
-0.2
-2.0
0.3
1.0



1.2
1.2
0.2
0.1



46 PRCC proline rich mitotic checkpoint control factor 5546 0 5.6 5.5
1.4
4.4
5.2
0.3
2.1
3.2
2.6
1.4
0.9
-0.5
0.1
0.9
1.3
2.4
1.8
1.6
1.4
-0.3
1.0
-0.8
2.2
1.6
1.7
0.8
3.0


47 DOT1L DOT1 like histone lysine methyltransferase 84444 0 5.5 6.6
1.7
3.1
-0.6
-0.0
-0.6
2.9
0.5
1.4
1.4
-0.6
-1.0
0.9
-1.4
-1.0
-0.7
1.1
-1.2
-1.6
0.5
1.9
0.9
0.6
3.3
2.5
1.5
-1.3
0.7
-0.6
48 POLR2E RNA polymerase II, I and III subunit E 5434 0 5.5 5.9
2.5
3.8
-0.9
1.1
1.1
1.2
1.5
1.3
0.2
0.1
1.1
1.0
0.5
-0.2
-0.4
-0.2
-0.9
-2.8
-0.2
0.3
-0.3
-0.8
0.7
0.1
-0.1
-0.9
-0.1
49 AP3D1 adaptor related protein complex 3 subunit delta 1 8943 0 5.5 6.4
2.5
3.3
0.4
-0.2
-1.0
3.1
1.7
-0.4
-0.9
1.0
1.7
3.0
0.4
-0.4
-1.3
1.6
1.0
-1.2
1.2
0.0
1.1
0.2
-0.1
0.9
-0.4
-1.6
0.6
50 PEX14 peroxisomal biogenesis factor 14 5195 0 5.5 4.5
2.0
5.2
1.0
-0.6
1.9
2.6
2.0
0.9
0.7
-0.4
0.1
-0.2
0.7
0.3
0.1
0.3
-0.8
-0.5
-0.2
1.4
-2.0
0.4
-0.5
0.6
0.8
0.2
0.5
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