Orthologous genes in OrthoFinder**

Species Gene Description
 gga-u.3   ISL2   ISL LIM homeobox 2 
 gga-r.3   ISL2   ISL LIM homeobox 2 
 gga-m.5   ISL2   ISL LIM homeobox 2 
 gga-u.3   ISL1   ISL LIM homeobox 1 
 hsa-u.4   ISL2   ISL LIM homeobox 2 
 hsa-u.4   ISL1   ISL LIM homeobox 1 
 mmu-u.4   Isl2   insulin related protein 2 (islet 2) 
 mmu-u.4   Isl1   ISL1 transcription factor, LIM/homeodomain 
 rno-u.3   Lmo1   LIM domain only 1 
 rno-u.3   Isl2   ISL LIM homeobox 2 
 rno-u.3   Isl1   ISL LIM homeobox 1 
 dre-u.3   isl2b   ISL LIM homeobox 2b 
 dre-u.3   isl2a   ISL LIM homeobox 2a 
 dme-u.3   tup   tailup 
 cel-u.3   mec-3   Mechanosensory protein 3 
 cel-u.3   lim-7   LIM/homeobox protein lim-7 

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Top 50 coexpressed genes to ISL2 (gga-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 gga3460   Fanconi anemia pathway  2 47 2.02
 gga3030   DNA replication  1 31 -
 gga3420   Nucleotide excision repair  1 38 -
 gga4514   Cell adhesion molecules  2 126 -
 gga4120   Ubiquitin mediated proteolysis  2 135 -

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gga:ISL2 (ISL LIM homeobox 2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

gga-u.3
for
ISL2
gga-r.3
for
ISL2
gga-m.5
for
ISL2
gga-u.3
for
ISL1
hsa-u.4
for
ISL2
hsa-u.4
for
ISL1
mmu-u.4
for
Isl2
mmu-u.4
for
Isl1
rno-u.3
for
Lmo1
rno-u.3
for
Isl2
rno-u.3
for
Isl1
dre-u.3
for
isl2b
dre-u.3
for
isl2a
dme-u.3
for
tup
cel-u.3
for
mec-3
cel-u.3
for
lim-7
1 ISL1 ISL LIM homeobox 1 396383 4.3 1.4
 2.5
 4.3
 2.8
 2.8
 4.7
 4.7
 1.9
0.3
 2.3
1.9
 2.3
0.3
 8.8
8.2
 8.2
7.1
0.4
 0.4
2 BICRA BRD4 interacting chromatin remodeling complex associated protein 101749950 3.7 2.0
0.2
 2.5
 -0.2
 0.1
 0.0
 -0.3
 0.2
 -0.3
 0.8
0.3
 1.5
1.0
 0.1

3 NHLH2 nescient helix-loop-helix 2 395578 3.6 1.8
 1.6
 2.5
2.4
 2.9
 0.1
 2.9
1.8
 3.3
1.3
 0.8
-0.0
 0.8
0.4
 0.4
0.1
 2.2
 2.0


4 NAB2 NGFI-A binding protein 2 100873158 3.6 1.9
-0.1
-1.0
 0.6
-0.0
 0.7
-0.7
 -0.3
-0.8
 -0.3
-1.5
 1.0
-1.0
 -0.3
-0.8
 0.1
-0.4
 0.5
0.1
 0.3
-0.9
 0.4
 -0.4
 -0.2
5 TBX21 T-box 21 100858002 3.5 1.9
-0.9
 1.5
 -0.8
 -0.3
 -0.9
 -0.7
 -0.7
 -0.5
 1.7
 0.2


6 CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 395921 3.4 0.9
 2.3
 0.3
 -0.2
 -0.9
 -0.7
 -0.2
 0.4
 -0.1
 -0.5
 0.6
 -2.3
-0.9
 0.7
7 MARCKSL1 MARCKS like 1 770764 3.4 1.6
 1.6
 1.1
 1.4
 -1.1
 -0.1
 -0.6
 1.1
 -0.1
 -0.4
 1.1
0.5
 1.0
0.9


8 RUNX3 runt related transcription factor 3 769687 3.4 1.8
0.9
0.1
 2.1
0.6
 0.1
-0.1
 1.2
0.9
 -0.0
-0.2
 0.0
 0.4
 -0.3
 1.1
0.8
 1.1
0.8
 4.2
2.9
 1.1
 1.4
9 LOC107049666 integrin beta-7-like 107049666 3.3 1.8













10 LOC107051419 amphoterin-induced protein 1-like 107051419 3.3 1.8
-0.2
 -0.5
 -0.6
 0.0
 0.3
 -0.9
 -0.3
 0.5
 -0.1
 -1.0


11 TBKBP1 TBK1 binding protein 1 430679 3.3 1.8
0.3
 1.7
 -0.6
 0.6
 -0.8
 1.4
 0.3
 -1.1
 1.4
 0.4


12 RBPMS2 RNA binding protein, mRNA processing factor 2 395678 3.3 1.0
 2.1
 1.7
0.4
 0.7
-0.4
 -0.1
-1.1
 1.2
1.2
 -0.2
-0.2
 -0.0
-0.9
 0.7
0.1
 -0.7
-1.5
 3.2
2.2
 2.4
1.6
 -1.3
 -0.6
 2.8
13 POLD4 DNA polymerase delta 4, accessory subunit 112532567 3.3 1.8
0.5
 -0.7
 -0.8

-1.1
 -0.8
 0.2
 1.3
 0.6


14 BAZ2A bromodomain adjacent to zinc finger domain 2A 101747779 3.2 1.8
0.3
0.0
 -0.0
 0.6
 0.3
-0.2
 1.0
-0.5
 0.2
-1.2
 1.2
1.1
 0.5
0.1
 1.1
0.9
 2.9
0.2
 0.2
 0.6
 0.7
15 LOC107056270 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like 107056270 3.2 1.8
-0.1
-0.2
 -1.0
-1.1
 -0.6
-0.8
 0.4
0.0
 0.4
-0.4
 0.2
-1.6
 -0.4
-0.7
 -0.4
-0.5
 0.6
-0.1
 0.2
-0.7
0.1
 0.5
16 RFX5 regulatory factor X5 100857912 3.2 1.7
-0.3
 0.3
 -0.7
 -0.4
 -1.0
 -1.3
 -0.6
 -0.2
 -0.2
 -0.3
 -0.4

17 RPA3 replication protein A3 420578 3.2 1.5
 1.5
 0.3
 -0.0
 0.3
 0.0
 -0.4
 -0.4
 -0.4
 1.3
 -0.5
 -1.8


18 LOC121107191 WAS/WASL-interacting protein family member 1-like 121107191 3.2 1.7













19 PRF1 perforin 1 101750363 3.1 1.7
-0.5
 -0.0
 -0.3
 -0.3
 -1.1
 -0.8
 -0.7
 0.2
 -0.3
 -0.3


20 RTN4RL2 reticulon 4 receptor like 2 425201 3.1 1.7
0.9
0.6
 -0.8
 0.5
 -0.9
 -0.9
 0.9
 0.0
 -0.5
 0.9
-0.1
 -0.4
-0.6
-0.6
 0.7
21 LOC107050992 ribonucleoprotein PTB-binding 1-like 107050992 3.1 1.7
-0.4
 2.0
 -0.1
 0.9
 -0.6
 0.8
 0.7
 -0.3
 0.2
 -0.9


22 TOX2 TOX high mobility group box family member 2 419156 3.1 1.6
 1.3
 2.5
2.2
 1.1
0.6
 0.7
0.7
 0.2
-0.3
 2.1
1.2
 0.5
0.5
 1.4
0.3
 1.9
0.5
 2.4
1.8
 2.7
0.3
 -0.8

23 LOC107055390 tristetraprolin-like 107055390 3.1 1.7
0.4
 0.8
 -0.7
 0.2
 -0.6
 -1.3
 -0.2
 -0.9
 0.1
-0.8
 0.8
-0.1
0.3
 1.2
24 FMC1 formation of mitochondrial complex V assembly factor 1 homolog 107053781 3.1 1.7
-0.2
 -0.4
 0.3
 0.2
 -0.6
 0.4
 0.4
 -0.0
 0.1
 0.2
 -0.9
 0.6
 -0.6
25 BARX1 BARX homeobox 1 374017 3.0 1.7
2.8
 4.1
 1.7




4.2
 2.8


26 LOC424727 structure-specific endonuclease subunit SLX1-like 424727 3.0 1.6
-1.1

-0.2
 0.2
 0.3
 -0.7
 -0.6
 0.1
 -0.3
 -0.6
 0.7
 0.8
27 NEUROD1 neuronal differentiation 1 395754 3.0 1.3
 1.5
 2.5
1.8
 0.1
-1.4
 1.3
0.5
 2.2
1.4
 2.0
1.9
 1.0
0.4
 0.5
-0.8
 0.0
-1.2
 5.7
5.3
 3.2
2.5
0.4
 2.5
28 GPS2 G protein pathway suppressor 2 121108913 2.9 1.6
0.4
 1.1
 -0.1
 -0.2
 0.4
 0.6
 -0.6
 -0.9
 1.0
 1.4


29 CCL19 C-C motif chemokine ligand 19 427406 2.9 1.3
 1.5
 1.4
 -0.1
 -0.5

-0.2
 0.1
 -0.6
 0.2
-1.2
 -0.8
-1.4


30 HMX1 H6 family homeobox 1 396546 2.9 1.7
 1.1
 2.2











31 LOC121112584 zinc finger and BTB domain-containing protein 9-like 121112584 2.9 1.6
-0.9
 -0.1
 0.3
 -0.0
 -0.5
 -0.7
 0.7
 0.5


-0.1
 1.1
32 NCS1 neuronal calcium sensor 1 396336 2.8 0.9
 1.8
 1.2
0.9
 0.7
0.2
 1.5
0.7
 0.9
-0.0
 1.1
0.8
 1.9
1.1
 1.9
0.4
 1.0
0.8
 2.0
-0.3
 2.0
1.6
 0.3
0.3
 1.3
1.1
 0.3
-0.8
33 LOC769646 uncharacterized LOC769646 769646 2.8 1.6













34 LOC100857859 uncharacterized LOC100857859 100857859 2.8 1.5
0.0
 -0.1
 0.4
 0.1
 0.2
 0.9
 1.0
 1.2
 -0.4
 0.2
 -0.4
 0.4
 -1.0
35 NTNG2 netrin G2 417171 2.8 1.3
 1.3
 1.5

0.6
 -1.4
 1.0
 0.4
 0.1




36 IFITM5 interferon induced transmembrane protein 5 422992 2.8 1.6
 1.0
 0.6



-0.8
 -0.6
 -0.2
 -0.5
 0.1


37 LRFN1 leucine rich repeat and fibronectin type III domain containing 1 101750437 2.7 1.5
1.5
1.0
 2.9
1.5
 3.3
0.1
 1.7
0.7
 0.5
0.4
 2.8
0.8
 1.6
0.9
 2.0
-0.0
 2.6
1.8
 1.8
0.5
0.5
 -0.0
38 KCNMB4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 417852 2.7 1.9
 0.7
 0.8
 0.2
 0.1

1.9
 0.6
 -0.3




39 K123 K123 protein 395873 2.7 0.4
 2.2
 0.1
-0.4
 -1.2
 -0.4
 -0.1
 -0.7
 0.3
 -0.4
 -0.3
 0.1
0.1
 0.0


40 ECM1 extracellular matrix protein 1 107049123 2.7 1.5
0.4
 -1.0
 -0.9
 -0.4
 0.5
 0.9
 -0.2
 -0.8
 -0.2
 -2.1


41 LOC101748577 uncharacterized LOC101748577 101748577 2.7 1.5
0.9
-0.2
 0.4
-0.0
 -0.3
-0.9
 -0.6
-0.7
 0.1
-0.3
 0.0
-0.2
 1.1
-0.0
 0.4
0.1
 1.3
0.6
 1.1
-0.1
 2.7
 -0.2
-0.3
 1.1
0.6
42 EBF1 EBF transcription factor 1 395512 2.7 1.6
 0.9
 3.5
1.5
 2.1
1.3
 2.7
1.9
 3.7
2.0
 3.5
3.0
 1.6
1.0
 2.5
1.5
 2.0
1.1
 2.8
2.4
 3.0
1.8
 5.8
 2.0
 1.8
43 PIAS3 protein inhibitor of activated STAT 3 107055114 2.7 1.5
2.2
0.6
 2.0
0.8
 1.3
0.6
 1.7
-0.4
 0.3
-0.4
 1.2
-0.5
 1.2
0.7
 -0.4
-0.4
 0.8
0.6
 0.6
0.5
 1.1
 0.3
 0.8
44 PLACL2 PLAC8 like 2 100857411 2.7 1.5
0.7
-0.1
 -0.6
 0.4

-1.2
 -0.2
 -0.1
 0.5
0.3
 1.8
0.6


45 UBE2L6 ubiquitin-conjugating enzyme E2L 6 100858073 2.7 1.5













46 MEA1 male-enhanced antigen 1 107052849 2.7 1.5
-0.2
 -1.7
 -0.5
 -0.2
 -0.6
 0.9
 -0.5
 -0.5
 -0.4
 -0.4


47 DCAF15 DDB1 and CUL4 associated factor 15 112530997 2.7 1.5
-0.4
 1.3
 0.7
 0.5
 0.6
 -0.2
 0.2
 -0.4
 -0.0
 0.1
 -0.1

48 LOC100858381 chromosome 11 open reading frame, human C19orf12-like 100858381 2.7 1.5
0.6
0.4

0.1
 0.0
 -1.3
 -0.8
 -1.2
 0.0
-0.3
 -0.2
-0.8
 -0.6
-1.5

49 LOC107051857 translation initiation factor IF-2-like 107051857 2.6 1.5
0.5
 2.0
 0.4
 1.4
 0.1
 -0.2
 -0.3
 -0.2
 -0.4
-0.4
 0.5
-0.2


50 LOC107051537 retinoic acid receptor gamma-like 107051537 2.6 1.5
0.4
-0.3
 0.8
-0.4
 1.4
-0.4
 0.3
0.1
 2.1
-0.7
 -0.1
-0.3
 -0.1
-0.5
 0.9
-1.0
 1.1
0.9
 3.5
2.2
-1.2
 0.3
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