Orthologous genes in OrthoFinder**

Species Gene Description
 dme-u.3   Trh   Tryptophan hydroxylase 
 dme-r.4   Trh   Tryptophan hydroxylase 
 dme-m.5   Trh   Tryptophan hydroxylase 
 dme-u.3   Hn   Henna 
 cel-u.3   tph-1   BH4_AAA_HYDROXYL_2 domain-containing protein 
 cel-u.3   pah-1   Phenylalanine-4-hydroxylase 
 hsa-u.4   TPH1   tryptophan hydroxylase 1 
 hsa-u.4   PAH   phenylalanine hydroxylase 
 mmu-u.4   Tph2   tryptophan hydroxylase 2 
 mmu-u.4   Pah   phenylalanine hydroxylase 
 rno-u.3   Tph1   tryptophan hydroxylase 1 
 rno-u.3   Tph2   tryptophan hydroxylase 2 
 rno-u.3   Pah   phenylalanine hydroxylase 
 gga-u.3   TPH2   tryptophan hydroxylase 2 
 gga-u.3   PAH   phenylalanine hydroxylase 
 dre-u.3   tph1b   tryptophan hydroxylase 1b 
 dre-u.3   tph2   tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) 
 dre-u.3   tph1a   tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a 
 mcc-u.3   TPH1   tryptophan hydroxylase 1 
 mcc-u.3   PAH   phenylalanine hydroxylase 
 cfa-u.3   PAH   phenylalanine hydroxylase 

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Top 50 coexpressed genes to Trh (dme-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dme4080   Neuroactive ligand-receptor interaction  4 53 4.20
 dme350   Tyrosine metabolism  2 20 2.53
 dme220   Arginine biosynthesis  1 18 -
 dme250   Alanine, aspartate and glutamate metabolism  1 29 -
 dme230   Purine metabolism  1 94 -

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dme:Trh (Tryptophan hydroxylase) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dme-u.3
for
Trh
dme-r.4
for
Trh
dme-m.5
for
Trh
dme-u.3
for
Hn
cel-u.3
for
tph-1
cel-u.3
for
pah-1
hsa-u.4
for
TPH1
hsa-u.4
for
PAH
mmu-u.4
for
Tph2
mmu-u.4
for
Pah
rno-u.3
for
Tph1
rno-u.3
for
Tph2
rno-u.3
for
Pah
gga-u.3
for
TPH2
gga-u.3
for
PAH
dre-u.3
for
tph1b
dre-u.3
for
tph2
dre-u.3
for
tph1a
mcc-u.3
for
TPH1
mcc-u.3
for
PAH
cfa-u.3
for
PAH
1 Trissin trissin 41890 Dmel_CG14871 6.0 2.8
 3.2

















2 FMRFa FMRFamide 36030 Dmel_CG2346 5.9 2.9
 3.0

















3 CG12239 uncharacterized protein 31509 Dmel_CG12239 5.8 3.2
 2.6

















4 CG15537 uncharacterized protein 43614 Dmel_CG15537 5.8 3.4
 2.4
 0.8

0.3
 0.7
 2.1
 0.2
 -0.5
 1.9
 1.5
 -0.4
 -0.5
 -0.6
 0.3
 1.2
 0.0
 0.9
5 Hug Hugin 41547 Dmel_CG6371 5.5 3.1
 2.4

















6 CG8401 uncharacterized protein 36770 Dmel_CG8401 5.2 1.9
 3.2
 0.4

0.0
 1.7
 -0.3
 -0.0
 -1.2
 -0.2
 -0.9

-0.9
 1.8
 1.4
 -0.3
 0.7
7 Crz Corazonin 41742 Dmel_CG3302 5.1 2.2
 2.9

















8 Pdf Pigment-dispersing factor 43193 Dmel_CG6496 5.0 2.5
 2.5

















9 Ilp2 Insulin-like peptide 2 39150 Dmel_CG8167 4.9 2.3
 2.7

















10 Ms Myosuppressin 44324 Dmel_CG6440 4.9 2.3
 2.6

















11 spab space blanket 35901 Dmel_CG8216 4.8 2.4
 2.4

















12 CG3009 uncharacterized protein 31402 Dmel_CG3009 4.7 2.3
 2.4
 4.2
1.5

-1.6
 1.1

0.3
 1.2
 -1.5
 1.2
-1.0
 0.6
0.2
 0.2
-0.7
 -0.8
-0.8
 0.5
0.4
 0.1
 -1.7
 0.1
13 Capa Capability 43541 Dmel_CG15520 4.6 2.1
 2.5

















14 Nos Nitric oxide synthase 34495 Dmel_CG6713 4.5 2.4
 2.1
 -0.2

0.2
0.1
 2.2
0.7
 1.7
0.6
 -0.5
-0.7
 1.1
0.6
 -0.3
-0.4
 0.1
-0.5
 0.1
-0.2
 0.6
0.3
 1.3
-0.9
 0.8
-0.7
 0.6
-0.8
 0.2
 2.0
 -0.5
-0.9
15 GluRIA Glutamate receptor IA 38742 Dmel_CG8442 4.5 1.5
 2.9
 0.3
-0.3
 1.5
 -0.2
 0.8
0.7
 2.2
1.2
 1.9
0.0
 0.4
-0.2
 0.4
0.3
 0.4
0.1
 0.6
0.4
 1.7
1.4
 1.4
0.5
 1.1
1.0
 0.4
-0.2
 0.9
0.8
 0.5
0.1
 1.8
0.8
 1.7
0.5
16 AstA Allatostatin A 42947 Dmel_CG13633 4.4 1.6
 2.7

















17 SerT Serotonin transporter 37895 Dmel_CG4545 4.3 2.5
 1.9
 0.7
-0.2
 2.6
2.1
 0.4
-0.2
 1.9
 0.7
 1.1
0.5
 0.1
-0.6
 2.9
0.8
 1.0
0.7
 -0.2
-1.1
 1.1
0.3
 1.0
-1.4
 0.8
-0.9
 1.9
1.2
 1.6
0.4
 0.6
 -0.0
18 Gycalpha99B Guanylyl cyclase alpha-subunit at 99B 43493 Dmel_CG1912 4.2 2.2
 2.0
 1.1

-0.4
 0.8
 0.1
 0.5


-1.2
 0.5
 -0.8
 -1.0
 0.2
 0.3
 -0.1
 0.5
19 Tbh Tyramine beta hydroxylase 31718 Dmel_CG1543 4.2 1.9
 2.3
 0.1
 0.2
 -0.2
 -0.5
 1.8
 1.2
 0.5
 -0.8
 2.2
 -1.1
 0.5
 -0.1
 -0.1
 1.0
 -0.0
 0.5
 1.9
20 Lmx1a LIM homeobox transcription factor 1 alpha 39406 Dmel_CG32105 4.1 1.9
 2.3
 0.1
-0.4
 0.8
 0.8
 -0.8
 -0.9
 0.6
 -1.0
 2.7
 0.6
 -0.7
 0.7
0.6
 -0.3
-0.9
 0.2
0.2
 2.6
0.7
 1.1
0.3

0.1
21 CG4328 uncharacterized protein 39405 Dmel_CG4328 4.1 1.7
 2.4
 0.1
-0.4
 0.8
 0.8
 -0.8
 -0.9
 0.6
 -1.0
 2.7
 0.6
 -0.7
 0.7
0.6
 -0.3
-0.9
 0.2
0.2
 2.6
0.7
 1.1
0.3

0.1
22 Aplip1 APP-like protein interacting protein 1 53472 Dmel_CG1200 4.1 2.6
 1.5
 0.6
 1.3
 -0.6
 0.6
0.3
 1.0
-0.0
 0.5
-0.0
 -0.5
-0.7
 0.2
-0.1
 1.4
0.9
 -0.1
-1.6
 1.7
1.2
 0.1
-0.6
 0.8
0.4
 1.9
0.3
 1.1
-0.4
 0.3
-0.3
 0.6
-0.7
 0.2
0.0
23 Gad1 Glutamic acid decarboxylase 1 38484 Dmel_CG14994 4.0 2.3
 1.8
 0.5
0.3
 0.1
 1.4
 0.9
0.7
 1.8
0.3
 0.4
0.0
 0.2
0.1
 0.8
0.1
 0.7
0.7
 1.1
-0.2
 2.0
0.7
 1.3
0.4
 2.3
0.9
 0.9
0.6
 0.7
0.5
 -0.0
-0.3
 0.7
0.1
 1.3
1.3
24 Mip Myoinhibiting peptide precursor 39933 Dmel_CG6456 4.0 2.0
 2.0

















25 CG17193 uncharacterized protein 50044 Dmel_CG17193 4.0 1.5
 2.4

















26 mAChR-A muscarinic Acetylcholine Receptor, A-type 37892 Dmel_CG4356 3.9 0.9
 3.0
 -0.1
 1.3
 1.1
 -0.7
 1.3
 0.2
-0.8
 -0.5
-0.9
 0.4
-1.2
 0.6
0.5
 1.7
-0.7
 2.9
 -1.3
 -0.2
 0.0
 0.7
 1.4
-0.6
 0.9
0.1
 0.3
27 CG13108 uncharacterized protein 34240 Dmel_CG13108 3.9 1.5
 2.4

















28 fd59A forkhead domain 59A 37631 Dmel_CG3668 3.9 1.3
 2.6
 0.2
-0.1
 1.8
1.4
 2.0
0.8
 0.2
0.2
 2.1
-0.2
 1.4
0.7
 1.4
0.1
 1.1
1.0
 0.9
0.3
 0.8
0.4
 2.0
1.6
 1.7
0.8
 1.9
1.6
 1.7
1.6
 2.2
1.7
 1.5
1.1
 1.8
0.8
 1.5
0.8
29 CG32225 uncharacterized protein 317926 Dmel_CG32225 3.9 2.9
 1.1

















30 CG13408 uncharacterized protein 42597 Dmel_CG13408 3.9 3.0
 1.0

















31 dpr18 defective proboscis extension response 18 32572 Dmel_CG14948 3.9 1.6
 2.3
 0.5
0.5
 0.2
 -1.2














32 natalisin natalisin 5740700 Dmel_CG34388 3.8 2.4
 1.5

















33 prim primacord 36814 Dmel_CG15704 3.8 1.8
 2.0

















34 SIFa SIFamide 3346202 Dmel_CG33527 3.8 2.3
 1.6

















35 dpr5 defective proboscis extension response 5 41381 Dmel_CG5308 3.8 2.1
 1.8
 0.5
0.5
 0.2
 -1.2














36 Dh44-R1 Diuretic hormone 44 receptor 1 36601 Dmel_CG8422 3.8 1.4
 2.4
 0.1
-0.1
 0.3
 1.3

0.5
 -0.4
 0.2
-0.0
 -0.1
-1.2
 0.6
-0.0
 1.3
0.3
 0.6
0.3
 0.4
 -0.5
 1.4
 -0.5
 2.1
37 Dop1R2 Dopamine 1-like receptor 2 43484 Dmel_CG18741 3.8 1.6
 2.2
 -1.2
 0.9
 -0.3
 -0.8
-1.4
 -0.3
-0.5
 1.5
-0.6
 1.6
0.2
 1.1
0.2
 -0.7
-0.8
 1.5
1.2
 -0.1
-0.7
 0.7
-0.5
 0.1
-0.2
 1.7
-0.0
 0.7
0.5
 1.2
0.2
 1.5
0.4
 0.0
-0.4
38 Tdc2 Tyrosine decarboxylase 2 246620 Dmel_CG30446 3.8 3.0
 0.9
 0.8
-0.3
 1.4
0.3
 1.4
-0.6
 0.2
 -0.9
 0.3
-0.1
 1.4
-0.3
 1.9
0.4
 0.5
-0.9
 1.4
-1.2
 -0.7
-0.7
 -0.2
-0.6
 1.8
-1.3
 3.7
2.2
 3.0
-0.5
 0.9
0.8
 2.8
-0.3
39 DIP-theta Dpr-interacting protein theta 33795 Dmel_CG31646 3.7 1.8
 2.0
 1.1
0.6
 0.7
0.5
 0.1
-0.1
 0.7
0.4
 2.7
1.1
 1.0
0.9
 0.9
0.6
 1.1
0.9
 0.5
0.3
 0.7
0.6
 0.3
-0.0
 -0.0
-0.6
 1.1
1.0
 0.9
-0.2
 1.9
1.5
 0.4
0.0
 0.7
0.0
 1.0
0.7
40 beat-Vb beaten path Vb 41583 Dmel_CG31298 3.7 1.8
 2.0
 1.1
0.7
















41 lncRNA:CR44832 long non-coding RNA:CR44832 19835061 Dmel_CR44832 3.7 2.2


















42 CG3078 uncharacterized protein 31211 Dmel_CG3078 3.7 1.7
 2.0

















43 Dsk Drosulfakinin 45845 Dmel_CG18090 3.7 2.0
 1.7

















44 CG18467 uncharacterized protein 36958 Dmel_CG18467 3.7 1.8
 1.9
 -0.3
-0.3
 -1.2
 -0.2
 -0.4
 0.2
 -0.7
 0.1
 -1.3
 -0.6
 -0.9
 0.4
 -0.2
 0.5
-0.4
 1.2
0.9
 0.7
0.0
 -0.4
 -0.3
 -0.6
45 CG30158 uncharacterized protein 50149 Dmel_CG30158 3.7 1.6
 2.1
 0.2
-0.0
 0.3
 0.7






-0.3
 -1.1
 1.1
0.5
 0.3
-0.5
 1.7
1.1


46 Hasp Hig-anchoring scaffold protein 35238 Dmel_CG10186 3.7 2.3
 1.4
 -0.0
 1.9
 0.9
 -0.8
 -0.9
 -0.9
 -0.3
 1.0
 -1.0
 0.4
 -1.2
 0.0


-0.2
 0.8
 0.1
47 Nmdar1 NMDA receptor 1 40665 Dmel_CG2902 3.6 1.1
 2.5
 -0.5
 2.0
 0.7
 -1.1
 -0.2
 0.5
 -1.1
 0.6
 0.6
 -0.3
 1.0
 0.7
 0.8
0.0
 0.0
-0.6
 0.2
-0.3
 -0.3
 -0.3
 0.2
48 CG15651 uncharacterized protein 37375 Dmel_CG15651 3.6 1.6
 2.1
 -0.2

2.0
 -0.4
 -0.3
 -0.2
 -0.5
 -0.7
 -0.6
 -1.8
 1.2
 -1.7
 0.8
 0.9
 0.6
 0.5
 -1.3
49 TBC1D16 TBC1 domain family member 16 34431 Dmel_CG5337 3.6 1.5
 2.2
 0.5
 2.5
 1.7
 -0.7
 0.5
 -1.3
 -0.1
 0.1
 0.4
 -1.9
 -0.1
 -0.5
 -1.1
 0.1
 1.4
 -0.5
 -0.4
 1.3
50 Orcokinin orcokinin 37806 Dmel_CG13565 3.6 1.8
 1.8

















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