Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4  PLEKHM2  pleckstrin homology and RUN domain containing M2 
 hsa-r.6  PLEKHM2  pleckstrin homology and RUN domain containing M2 
 hsa-m.7  PLEKHM2  pleckstrin homology and RUN domain containing M2 
 hsa-m2.4  PLEKHM2  pleckstrin homology and RUN domain containing M2 
 mcc-u.3  PLEKHM2  pleckstrin homology and RUN domain containing M2 
 mmu-u.4  Plekhm2  pleckstrin homology domain containing, family M (with RUN domain) member 2 
 rno-u.3  Plekhm2  pleckstrin homology and RUN domain containing M2 
 cfa-u.3  PLEKHM2  pleckstrin homology and RUN domain containing M2 
 gga-u.3  PLEKHM2  pleckstrin homology and RUN domain containing M2 
 dre-u.3  plekhm2  pleckstrin homology domain containing, family M (with RUN domain) member 2 
 dme-u.3  prd1  pruning defect 1 

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Top 50 coexpressed genes to PLEKHM2 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa5022   Pathways of neurodegeneration - multiple diseases  5 408 2.13
 hsa4137   Mitophagy - animal  3 66 2.99
 hsa4150   mTOR signaling pathway  3 140 2.07
 hsa5165   Human papillomavirus infection  4 331 -
 hsa5200   Pathways in cancer  4 531 -

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hsa:PLEKHM2 (pleckstrin homology and RUN domain containing M2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID CoexPub LINK Target Reference

hsa-u.4
for
PLEKHM2


hsa-r.6
for
PLEKHM2


hsa-m.7
for
PLEKHM2


hsa-m2.4
for
PLEKHM2


mcc-u.3
for
PLEKHM2


mmu-u.4
for
Plekhm2


rno-u.3
for
Plekhm2


cfa-u.3
for
PLEKHM2


gga-u.3
for
PLEKHM2


dre-u.3
for
plekhm2


dme-u.3
for
prd1

1 ZBTB17 zinc finger and BTB domain containing 17 7709 0 10.0 10.7
4.2
6.9
5.1
4.2
4.5
3.4
4.1
2.4

2 BAP1 BRCA1 associated protein 1 8314 0 7.4 7.2
2.5
5.8
5.6
1.6
3.3
1.9
3.6
0.7
2.6
3 CLCN7 chloride voltage-gated channel 7 1186 0 7.4 8.0
2.7
5.0
4.1
4.4
2.3
3.2
3.0
3.1
0.0
4 MAP7D1 MAP7 domain containing 1 55700 0 7.2 7.8
3.1
4.8
3.8
3.6
3.3
5.5
3.3
-1.1

5 FBXO42 F-box protein 42 54455 0 6.8 6.2
3.1
5.8
1.9
2.4

2.4
3.8
1.6
2.1
6 DVL1 dishevelled segment polarity protein 1 1855 0 6.7 7.4
2.6
4.3
4.3
3.0
4.0
1.0
2.5
1.5
3.3
1.6
2.7
2.2
1.4
1.2
-0.6
7 MFN2 mitofusin 2 9927 0 6.6 5.8
1.8
5.7
0.6
-0.7
1.4
1.1
3.6
2.9
2.3
-0.3
3.7
1.9
0.1
-0.2
2.5
-0.7
8 GPATCH3 G-patch domain containing 3 63906 0 6.5 6.6
4.1
4.9
1.5
2.7
0.1
1.2
0.9
1.7

9 SLC66A1 solute carrier family 66 member 1 54896 0 6.2 6.1
2.9
4.9
0.4
2.2
-0.2
2.7
1.8
1.2

10 STRN4 striatin 4 29888 0 6.2 5.8
2.1
5.0
3.7
0.5
1.4
1.3
3.7
1.7
3.4
2.1
2.6
2.3
1.2
0.8
1.8
11 IRAK1 interleukin 1 receptor associated kinase 1 3654 0 6.2 6.9
2.0
4.0
1.8
1.9
0.2
5.0

1.9

12 SZRD1 SUZ RNA binding domain containing 1 26099 0 6.1 5.1
2.5
5.7
1.3
0.9
1.4
1.2
1.7
0.9
0.3
13 SMG5 SMG5 nonsense mediated mRNA decay factor 23381 0 6.0 6.0
2.5
4.5
3.1
3.6
3.4
0.2
2.5
1.5
1.4
2.5
14 SBF1 SET binding factor 1 6305 0 5.9 6.7
2.5
3.7
3.3
-0.7
2.3
1.4
3.9
0.9
2.9
0.7
1.8
-0.6
1.5
0.9
9.7
15 UBR4 ubiquitin protein ligase E3 component n-recognin 4 23352 0 5.9 5.3
2.5
5.1
2.0
0.9
1.7
1.8
3.3
1.3
4.1
16 KLHL21 kelch like family member 21 9903 0 5.9 5.8
2.7
4.5
1.4
1.8
1.4
4.1
2.6
0.3

17 CLCN6 chloride voltage-gated channel 6 1185 0 5.8 5.6
2.4
4.6
4.0
1.6
1.1
2.9
0.2
3.4

18 TOM1 target of myb1 membrane trafficking protein 10043 0 5.8 6.6
3.3
3.6
2.7
2.4
3.6
2.0
2.7
2.5
3.3
0.3
3.5
0.3
2.7
-0.6
0.8
19 TESK1 testis associated actin remodelling kinase 1 7016 0 5.6 5.1
2.3
4.7
3.7
1.4
4.1
-0.9
4.0
1.7
2.3
0.1
1.8
-0.8
3.8
0.1
1.3
20 DVL3 dishevelled segment polarity protein 3 1857 0 5.5 4.1
1.4
5.6
4.3
3.0
4.0
1.0
2.5
1.5
3.3
1.6
2.7
2.2
1.4
1.2
-0.6
21 PPP1R12C protein phosphatase 1 regulatory subunit 12C 54776 0 5.5 6.0
1.6
3.6
2.0
1.9
4.1
2.7
4.4
2.4
2.5
0.4

22 MAPKAPK2 MAPK activated protein kinase 2 9261 0 5.3 5.6
1.8
3.7
2.7
2.1
3.8
0.6
3.5
3.2
3.4
0.6
4.5
-1.1
1.3
1.0
-1.2
23 PPP6R1 protein phosphatase 6 regulatory subunit 1 22870 0 5.3 4.7
2.8
4.7
4.0
2.6
1.6
0.6
1.1
1.1
3.8
1.7
0.5
-0.4
2.0
1.6
2.3
24 MGAT4B alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B 11282 0 5.2 5.0
2.2
4.2
1.4
-0.9
2.8
-0.2
0.2
-0.7
2.7
-0.1
3.2
0.4
0.6
-0.0
3.5
25 UBXN6 UBX domain protein 6 80700 0 5.2 5.1
2.8
4.0
2.0
2.3
3.3
3.3
2.5
1.9

26 PI4KB phosphatidylinositol 4-kinase beta 5298 0 5.2 5.0
2.5
4.1
3.8
2.7
0.8
0.7
4.2
0.6
1.9
27 MARK4 microtubule affinity regulating kinase 4 57787 0 5.2 4.8
1.8
4.3
1.5
2.7
3.9
2.2

0.3
-0.3

28 PACS2 phosphofurin acidic cluster sorting protein 2 23241 0 5.2 5.1
1.8
4.0
3.2
3.0
3.9
0.1
2.6
2.0
4.5
1.0
2.4
2.1
2.4
2.3
0.3
29 PEX14 peroxisomal biogenesis factor 14 5195 0 5.2 5.2
2.6
3.8
2.1
1.3
1.5
2.8
1.9
1.7
-1.1
30 CIZ1 CDKN1A interacting zinc finger protein 1 25792 0 5.1 5.0
1.7
4.0
5.0
2.5
2.0
0.3
0.6
2.6
2.0
-0.8
31 FBRS fibrosin 64319 0 5.1 5.0
1.7
4.0
3.5
3.3
2.4
1.6



32 MTOR mechanistic target of rapamycin kinase 2475 0 5.1 3.0
2.6
6.0
2.8
2.9
0.4
3.4
2.8
-1.1
1.5
33 GGA1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 26088 0 5.1 6.0
2.1
2.9
3.3
3.0
3.1
1.2
4.7
2.1
3.1
2.4
2.3
0.6
3.0
1.4
-1.2
34 SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 6455 0 5.0 5.5
2.6
3.3
3.9
0.8
0.6
-0.9
1.8
1.5
2.1
-0.6
1.6
-0.4
1.1
0.7
4.9
35 INPPL1 inositol polyphosphate phosphatase like 1 3636 0 5.0 4.9
2.6
3.9
3.2
1.5
2.7
4.6
2.1
0.4

36 UPF1 UPF1 RNA helicase and ATPase 5976 0 5.0 5.0
2.6
3.8
2.8
0.7
1.7
-0.2
1.6
0.4
-0.2
37 SCYL1 SCY1 like pseudokinase 1 57410 0 5.0 5.6
2.3
3.2

2.8
2.3
1.5
-0.1
-0.5
3.3
38 STK40 serine/threonine kinase 40 83931 0 5.0 5.0
2.8
3.8
3.2
1.2
3.1
-0.0
2.1
0.3

39 MAST2 microtubule associated serine/threonine kinase 2 23139 0 5.0 4.7
1.6
4.0
2.7
3.0
4.0
4.5
1.7


40 FZR1 fizzy and cell division cycle 20 related 1 51343 0 5.0 5.5
1.4
3.3
1.9
0.4
0.3
2.3
-0.2
1.7
-0.2
0.2
-0.6
1.0
0.5
1.0
-0.3
41 RERE arginine-glutamic acid dipeptide repeats 473 0 5.0 4.0
2.3
4.7
1.1
1.6
1.8
0.6
1.4
0.6
2.2
42 ATG9A autophagy related 9A 79065 0 4.9 4.5
1.9
4.1
4.6
1.1
1.5
0.0
2.5
1.2
1.5
0.5
5.8
1.8
3.1
1.9
2.4
43 NR1H2 nuclear receptor subfamily 1 group H member 2 7376 0 4.9 5.5
3.1
3.1
3.7
-1.0
1.2
1.1
4.1
-0.6
3.2
0.3
3.1
2.1
-0.7
44 TFE3 transcription factor binding to IGHM enhancer 3 7030 0 4.9 4.6
2.1
4.0
2.4
2.1
2.4
2.1
2.8
2.2
2.5
2.3
3.4
1.3
1.7
1.6
1.0
45 CSNK1G2 casein kinase 1 gamma 2 1455 0 4.9 5.2
2.6
3.4
3.3
1.4
1.3
0.1
3.5
-0.5
1.8
-0.7
2.0
0.7
3.7
1.3
-0.1
46 MTHFR methylenetetrahydrofolate reductase 4524 0 4.9 4.0
2.0
4.6
0.6
3.0
-0.6
2.9
1.2
-1.0
-0.5
47 EDC4 enhancer of mRNA decapping 4 23644 0 4.9 5.0
1.4
3.5
3.4
1.6
1.7
0.5
1.4
-0.9
0.0
48 GRK2 G protein-coupled receptor kinase 2 156 0 4.9 5.6
0.9
3.0
3.3
2.7
3.1
1.9
2.8
0.3
2.1
1.0
1.9
0.7
2.6
2.2
49 UBE2J2 ubiquitin conjugating enzyme E2 J2 118424 0 4.9 4.7
3.0
3.9
1.6
1.7
1.1
0.8
0.2
1.5
1.6
50 TPRA1 transmembrane protein adipocyte associated 1 131601 0 4.9 4.8
2.3
3.7
3.1
1.2
1.0
0.8
0.5
2.6

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