Orthologous genes in OrthoFinder**

Species Gene Description
 fca-r.1   SRD5A1   steroid 5 alpha-reductase 1 
 cfa-u.3   SRD5A1   steroid 5 alpha-reductase 1 
 hsa-u.4   SRD5A1   steroid 5 alpha-reductase 1 
 hsa-u.4   SRD5A2   steroid 5 alpha-reductase 2 
 mmu-u.4   Srd5a2   steroid 5 alpha-reductase 2 
 mmu-u.4   Srd5a1   steroid 5 alpha-reductase 1 
 rno-u.3   Srd5a1   steroid 5 alpha-reductase 1 
 mcc-u.3   SRD5A1   steroid 5 alpha-reductase 1 
 gga-u.3   SRD5A1   steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 
 gga-u.3   SRD5A2   steroid 5 alpha-reductase 2 
 dre-u.3   srd5a2a   steroid-5-alpha-reductase, alpha polypeptide 2a 
 cel-u.3   ZK1251.3   3-oxo-5-alpha-steroid 4-dehydrogenase 
 cel-u.3   F42F12.3   3-oxo-5-alpha-steroid 4-dehydrogenase 
 cel-u.3   F19H6.4   3-oxo-5-alpha-steroid 4-dehydrogenase 
 spo-u.3   SPCC126.08c   putative lectin family glycoprotein receptor 

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Top 50 coexpressed genes to SRD5A1 (fca-r.1 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 fca5152   Tuberculosis  6 163 5.47
 fca4142   Lysosome  5 130 4.72
 fca4145   Phagosome  4 152 3.23
 fca5170   Human immunodeficiency virus 1 infection  4 194 2.83
 fca4144   Endocytosis  3 248 -

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fca:SRD5A1 (steroid 5 alpha-reductase 1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

fca-r.1
for
SRD5A1
cfa-u.3
for
SRD5A1
hsa-u.4
for
SRD5A1
hsa-u.4
for
SRD5A2
mmu-u.4
for
Srd5a2
mmu-u.4
for
Srd5a1
rno-u.3
for
Srd5a1
mcc-u.3
for
SRD5A1
gga-u.3
for
SRD5A1
gga-u.3
for
SRD5A2
dre-u.3
for
srd5a2a
cel-u.3
for
ZK1251.3
cel-u.3
for
F42F12.3
cel-u.3
for
F19H6.4
spo-u.3
for
SPCC126.08c
1 AP2M1 adaptor related protein complex 2 subunit mu 1 101088686 4.6 2.0
0.6
 0.8
0.4
 0.7
-0.1
 -0.2
-0.4
 0.4
0.2
 1.0
0.1
 0.1
0.0
 0.1
-0.8
 -0.1
-0.4
 1.1
0.6
 1.0
0.5
 2.5
1.9
 0.6
-0.1
2 AP1S1 adaptor related protein complex 1 subunit sigma 1 101081183 4.4 -0.4
-0.5
 2.9
2.1
 -0.2
-0.2
 1.0
0.3
 1.2
0.6
 -0.4
-0.5
 1.9
1.2
 0.8
-0.9
 0.2
0.1
 1.5
1.3
 0.2
-0.6
 2.2
-0.1
 0.8
-1.1
3 TMBIM6 transmembrane BAX inhibitor motif containing 6 101084551 4.2 0.9
 0.7
 1.4
 0.6
 0.4
 1.0
 0.7
 0.2
 -1.5
 0.5


2.2
4 ACAT2 acetyl-CoA acetyltransferase 2 101093863 4.1 -0.7
 0.9
 0.4
 2.0
1.1
 2.1
1.4
 3.0
0.4
1.5
 -1.0
 0.8



5 TBCB tubulin folding cofactor B 101081941 4.1 0.1
 1.7
 0.1
 -0.4
 0.4
 -0.1
 1.5
 -1.8
 -0.4
 0.5
 -0.8
 -0.1
 -0.6
6 HACD3 3-hydroxyacyl-CoA dehydratase 3 101084111 4.1 1.5
-0.5
 1.0
-0.4
 1.3
-0.1
 -0.2
-0.3
 1.5
0.1
 2.6
-0.4
 1.5
-0.3
 -0.0
-0.7
 1.6
-0.2
 1.5
0.4
 -0.1
 5.6
 -1.2
7 RAB5C RAB5C, member RAS oncogene family 101094966 4.1 2.7
1.1
 0.7
-0.1
 1.9
-0.3
 2.4
0.3
 0.2
0.1
 1.6
1.0
 0.9
-0.4
 0.9
-0.2
 0.9
0.2
 0.6
0.5
 -0.8
 0.5
 -0.1
8 ABHD12 abhydrolase domain containing 12, lysophospholipase 101091357 4.0 1.8
 2.7
 -0.8
 -0.0
 0.5
 0.8
 1.8
 1.8
0.1
 0.9
-0.5
 1.2
-0.5
 -0.4
 0.6
 0.1
 0.1
9 EML2 EMAP like 2 101094309 3.9 0.7
0.5
 -0.5
-0.8
 0.5
-0.3
 0.3
-0.1
 1.0
0.8
 1.2
0.7
 1.0
0.2
 1.2
0.5
 0.7
0.1
 -0.3
-0.3
 0.2
 -0.1
 -1.3
 0.2
-0.2
10 MAPK11 mitogen-activated protein kinase 11 105260786 3.9 0.3
-0.4
 1.2
0.3
 0.0
-0.8
 0.1
-0.1
 0.0
0.0
 0.4
0.2
 2.3
-0.0
 1.3
1.2
 2.1
1.3
 1.4
0.9
 0.8
-0.2
 1.2
0.3
 0.6
-0.7
 1.3
11 COPG1 COPI coat complex subunit gamma 1 101085446 3.8 0.6
-0.5
 0.7
-0.6
 -0.4
-0.7
 0.2
-0.8
 1.1
0.6
 1.1
-0.8
 -0.3
-0.8
 -0.2
-0.6
 -0.8
-0.9
 -0.4
 -0.6
 0.5
 0.3
12 HARS1 histidyl-tRNA synthetase 1 101097371 3.8 -1.0
-2.1
 0.3
0.2
 0.0
-0.1
 0.5
-0.4
 0.6
-0.4
 -0.4
-0.7
 -0.5
-1.0
 0.5
-1.8
 -1.0
-1.6
 -0.1
 0.3
 0.3
 -0.9
 -1.7
13 ABAT 4-aminobutyrate aminotransferase 101089064 3.8 -1.0
 1.3
 0.7
 1.6
 0.4
 0.5
 1.6
 0.7
 -0.7
 1.4
 0.4
 1.3
 -0.7
 -0.8
14 CASP9 caspase 9 768260 3.8 -0.5
 -1.2
 -0.4
 1.3
 0.5
 -0.3
 0.5
 1.3
 -1.2
 -0.8



15 NCKIPSD NCK interacting protein with SH3 domain 101099944 3.8 1.8
 1.2
 -1.4
 -1.0
 0.5
 0.2
 0.4
 -1.1
 -0.1



0.1
16 SNX12 sorting nexin 12 101089586 3.8 1.4
-0.1
 2.5
1.2
 -0.2
-0.7
 0.6
-0.8
 -0.3
-0.4
 0.7
-0.4
 -0.4
-1.4
 0.8
-1.0
 1.1
0.5
 0.0
-0.2
 -0.9
 0.7
 1.3
17 TOLLIP toll interacting protein 101095614 3.8 1.7
 1.4
 0.2
 -0.5
 0.0
 0.7
 0.2
 1.5
 1.6
 -0.5
 -0.9
 0.1
 0.1
18 ATP6AP1 ATPase H+ transporting accessory protein 1 101091770 3.7 2.0
 0.7
 -0.3
 -0.1
 -1.3
 0.8
-1.5
 -0.5
 -0.1
-0.4
 -0.0
-0.6
 -0.1
-0.4
 -0.2
 0.3
 0.2
 2.3
1.4
19 YKT6 YKT6 v-SNARE homolog 101095563 3.7 0.4
 0.2
 -0.5
 -0.5
 0.7
 -0.7
 -0.8
 0.1
 -1.3
 0.1
 -0.2
 0.4
 0.2
20 KCTD11 potassium channel tetramerization domain containing 11 102899433 3.7 0.8

-0.6
 0.8
 1.5
 -0.3






21 ATP6V0D1 ATPase H+ transporting V0 subunit d1 101100610 3.6 1.2
0.2
 0.2
-0.4
 0.4
-0.3
 1.5
-0.1
 -0.6
-1.5
 0.3
0.3
 0.2
-1.0
 0.4
-0.0
 0.3
-1.6
 -0.5
 -0.1
 1.2
 1.0
22 YIPF1 Yip1 domain family member 1 101095115 3.6 1.7
0.4
 0.5
 -0.1
-0.7
 0.3
-0.6
 1.0
0.6
 1.0
0.3
 2.5
2.1
 -1.4
 -1.1
 -0.7
-0.8
 -0.8
 -0.2
 0.3
23 PPP1R7 protein phosphatase 1 regulatory subunit 7 101090203 3.6 0.7
 0.5
 0.3
 -0.0
 0.1
 0.7
 2.7
 -0.3
 0.9
 -0.0



24 FAM98C family with sequence similarity 98 member C 101094718 3.6 -0.4
 0.7
 -0.5
 -0.9
 1.8
 0.3
 -0.0






25 ACTR1A actin related protein 1A 101081833 3.6 2.3
0.9
 1.3
0.5
 0.9
0.6
 3.0
0.2
 0.8
0.3
 0.2
-0.1
 1.1
0.5
 0.4
0.2
 1.0
0.7
 2.0
0.3
 0.3
0.3
 0.4
-0.5
 0.8
0.5
26 LAMP1 lysosomal associated membrane protein 1 100125859 3.6 1.1
0.7
 0.7
0.5
 0.3
 0.5
0.1
 1.3
-0.1
 0.5
0.0
 0.3
0.1
 0.8
0.0
 0.1
-0.6
 -0.9
-1.0
 0.4
-0.5
 2.9
2.8
 1.3
-1.1
27 VPS51 VPS51 subunit of GARP complex 101096167 3.6 0.9
 -0.3
 -0.4
 0.8
 -0.1
 0.8
-0.9
 0.8
 -1.3
 -0.2
 -1.4
 -0.3
 -0.7
 -2.1
 -1.1
28 COPE COPI coat complex subunit epsilon 101089336 3.6 0.1
 -0.1
 -0.7
 0.1
 0.7
 0.2
 -0.1
 0.3
 -0.9
 -0.3
 1.1
 0.2
 1.2
29 MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 101085070 3.6 1.4
0.2
 1.7
0.8
 0.7
-0.3
 0.2
-0.7
 1.0
-0.2
 0.1
-0.2
 0.5
0.4
 0.7
-0.2
 0.9
0.6
 0.2
-0.9
 -0.5
 -0.6
 -0.9
 -1.0
30 KIAA0930 KIAA0930 101094610 3.6 0.6
 2.2
 -0.9
 -0.9
 1.2
-0.3
 2.3
 -0.7
 -0.1
 -0.3
 0.3
 1.5
31 AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 101096064 3.5 2.6
0.3
 1.4
1.0
 0.0
-1.1
 -0.2
-0.7
 0.5
-0.6
 0.2
-0.3
 0.6
-0.9
 0.5
0.1
 0.8
-2.3
 0.5
 -0.3
-0.8
 2.5
1.4
 1.7
-1.9
 1.7
32 DPP3 dipeptidyl peptidase 3 101099587 3.5 0.3
 0.5
 0.1
 -0.3
 2.0
 1.4
 -0.2

-0.7
 0.2
 -0.3
 0.2
33 PIGT phosphatidylinositol glycan anchor biosynthesis class T 101088150 3.5 1.3
 -0.1
 0.1
 -0.2
 2.3
 0.5
 -1.1
 0.6
 -0.3
 -0.7
 0.5
 0.7
 -0.7
 -0.4
34 CLPTM1L CLPTM1 like 101080689 3.5 1.6
 2.1
 0.5
 -0.4
 -0.4
 1.5
 0.7
 0.6
 -1.3
 0.6
 0.3
 -0.6
 -1.6
35 SMPD1 sphingomyelin phosphodiesterase 1 101099497 3.5 1.8
-1.8
 1.5
-0.3
 0.3
-0.3
 -0.0
-0.2
 1.2
-0.1
 1.5
0.2
 0.3
0.3
 2.0
0.8
 0.9
0.8
 0.7
0.6
 0.6
0.6
 2.6
1.7
 -0.3
-0.5
 -0.4
36 PRKCSH protein kinase C substrate 80K-H 101081869 3.5 0.7
 0.3
 -0.5
 0.5
 -0.2
 0.7
 -0.0

0.7
 -1.6
 -0.5
 0.3
 1.1
37 PI4K2A phosphatidylinositol 4-kinase type 2 alpha 101088190 3.5 1.6
0.3
 3.3
 1.0
 0.1
-0.7
 1.1
1.0
 0.4
0.2
 2.0
-1.6
 2.4
2.3
 0.7
-0.9
 -0.4
-2.1
 0.3
-1.1
 0.3
-0.2
 1.7
0.0
 0.5
38 SLC25A44 solute carrier family 25 member 44 101083902 3.5
-0.1
 -0.7
 -0.9
 1.0
 1.2
 -1.0
 1.0
 0.9
 1.0
0.5
 3.3
1.3
 0.8
-0.3
 -0.7
-3.1
39 PTPA protein phosphatase 2 phosphatase activator 101084914 3.5 1.9
 1.2
 0.0
 -1.5
 0.3
 -0.3
 1.0
 0.1
 -1.5
 -0.3
 0.6
 1.5
 1.1
40 OGFOD2 2-oxoglutarate and iron dependent oxygenase domain containing 2 101087874 3.4 -0.1
 -0.4
 -0.3
 0.5
 1.2
 -0.4
 1.1
 0.5
 -0.2
 -1.7



41 SLC35F6 solute carrier family 35 member F6 101092100 3.4 0.8
 0.9
 -0.2
 0.5
 -0.4
 1.9
 -0.5
 2.2
 -0.4
 -0.9
 0.2
 1.8
 1.1
 -1.1
42 GNA11 G protein subunit alpha 11 101086541 3.4 1.6
1.2
 1.6
1.3
 2.4
1.2
 3.3
1.7
 1.4
1.1
 1.2
0.6
 1.8
1.5
 1.1
0.2
 1.1
0.7
 2.0
1.3
 1.2
0.9
 1.0
0.4
 1.2
0.3
43 ZDHHC3 zinc finger DHHC-type palmitoyltransferase 3 101081449 3.4 1.6
1.6
 1.1
0.6
 -0.5
-1.4
 -0.5
-0.8
 2.2
0.4
 0.5
0.2
 0.1
-2.3
 1.2
-0.5
 2.2
-0.4
 -0.1
-0.4
 -0.2
 -0.1
 -1.2
44 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 101096843 3.4 -0.0
 -1.8
 -1.2
 0.4
 0.5
 0.0
 -0.8
 -0.2
 -1.3
 0.4
-0.5
 -1.1
 1.5
 1.8
45 ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit 101096662 3.4 -0.4
 -0.8
 0.2
 -0.4
 1.4
 -0.1
 0.7
 -0.4
 -1.3
 -0.2
 -0.5
 -0.4
 0.3
 0.1
46 ALKBH6 alkB homolog 6 101087627 3.4 -0.5
 0.3
 -0.2
 -1.0
 0.2
 0.0
 -0.3

0.3
 -1.4
 1.1
 -0.0
47 MED22 mediator complex subunit 22 101084750 3.3 1.0
 0.9
 -0.6
 0.0
 0.2
 0.4
 2.3
 -0.5
 -0.3
 -1.0
 -0.2
 0.4
 0.0
48 MTCH1 mitochondrial carrier 1 101093522 3.3 0.3
-0.0
 2.5
1.1
 0.1
-1.1
 -0.3
-0.7
 0.6
0.5
 0.5
0.3
 0.2
-1.1
 0.1
 -0.7
 0.2
 -0.4
 0.2
 0.9
49 AARS1 alanyl-tRNA synthetase 1 101088636 3.3 0.4
 -0.5
-1.3
 0.1
-1.9
 0.3
-0.4
 0.8
-0.6
 0.5
0.1
 -0.1
-1.1
 -1.1
-1.1
 -0.1
-1.7
 -0.2
-0.3
 -0.1
-0.9
 0.7
-1.3
 1.6
-2.5
50 DESI1 desumoylating isopeptidase 1 101081148 3.3 0.1
 3.3
 0.1
 -1.4
 2.0
 2.6
 1.7
 2.8
 -2.5
 1.3
-0.3



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