Orthologous genes in OrthoFinder**

Species Gene Description
 dre-u.3   cry1a   cryptochrome circadian regulator 1a 
 dre-r.3   cry1a   cryptochrome circadian regulator 1a 
 dre-m.5   cry1a   cryptochrome circadian regulator 1a 
 dre-u.3   si:ch1073-390k14.1   si:ch1073-390k14.1 
 dre-u.3   cry3a   cryptochrome circadian regulator 3a 
 dre-u.3   cry3b   cryptochrome circadian regulator 3b 
 hsa-u.4   CRY1   cryptochrome circadian regulator 1 
 hsa-u.4   CRY2   cryptochrome circadian regulator 2 
 mmu-u.4   Cry2   cryptochrome 2 (photolyase-like) 
 mmu-u.4   Cry1   cryptochrome 1 (photolyase-like) 
 rno-u.3   Cry1   cryptochrome circadian regulator 1 
 rno-u.3   Cry2   cryptochrome circadian regulator 2 
 gga-u.3   395100   cryptochrome 4 
 gga-u.3   CRY1   cryptochrome circadian regulator 1 
 gga-u.3   CRY2   cryptochrome circadian regulator 2 
 mcc-u.3   CRY1   cryptochrome circadian regulator 1 
 mcc-u.3   CRY2   cryptochrome circadian regulator 2 
 cfa-u.3   CRY1   cryptochrome circadian regulator 1 
 cfa-u.3   CRY2   cryptochrome circadian regulator 2 
 dme-u.3   phr6-4   (6-4)-photolyase 
 dme-u.3   cry   cryptochrome 
 sce-u.3   PHR1   deoxyribodipyrimidine photo-lyase PHR1 
 spo-u.3   vma9   putative V-type ATPase V0 subunit e 

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Top 50 coexpressed genes to cry1a (dre-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre3420   Nucleotide excision repair  2 44 2.28
 dre270   Cysteine and methionine metabolism  2 56 2.08
 dre590   Arachidonic acid metabolism  1 62 -
 dre330   Arginine and proline metabolism  1 68 -
 dre4141   Protein processing in endoplasmic reticulum  2 202 -

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dre:cry1a (cryptochrome circadian regulator 1a) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-u.3
for
cry1a
dre-r.3
for
cry1a
dre-m.5
for
cry1a
dre-u.3
for
si:ch1073-390k14.1
dre-u.3
for
cry3a
dre-u.3
for
cry3b
hsa-u.4
for
CRY1
hsa-u.4
for
CRY2
mmu-u.4
for
Cry2
mmu-u.4
for
Cry1
rno-u.3
for
Cry1
rno-u.3
for
Cry2
gga-u.3
for
395100
gga-u.3
for
CRY1
gga-u.3
for
CRY2
mcc-u.3
for
CRY1
mcc-u.3
for
CRY2
cfa-u.3
for
CRY1
cfa-u.3
for
CRY2
dme-u.3
for
phr6-4
dme-u.3
for
cry
sce-u.3
for
PHR1
spo-u.3
for
vma9
1 per2 period circadian clock 2 140633 18.2 8.7
 7.8
 10.1
4.7
 1.5
0.3
 4.8
-2.9
 2.0
1.0
 9.1
6.8
 9.9
8.4
 4.1
1.3
 4.5
1.0
 8.9
5.8
 3.0
1.6
 4.1
0.1
 5.0
4.3
 1.3
0.9
 6.1
3.6
 0.4
0.3
 4.8
3.5
 0.9
 0.5
0.9
0.2
2 lonrf1l LON peptidase N-terminal domain and ring finger 1, like 100317496 14.9 7.7
7.8
6.1
 2.7
1.8
 4.5
2.8
 4.1
0.6
 1.2
0.2
 4.5
0.1
 6.7
3.7
 8.3
3.9
 3.8
0.7
 2.8
2.0
 3.2
3.0
 4.9
1.5
 1.3
0.6
 0.8
0.5
 2.0
1.9
 0.5
0.1
 -1.1
 -0.3
0.4
3 tefa TEF transcription factor, PAR bZIP family member a 30674 13.2 7.5
 4.4
 7.1
3.5
 3.6
1.5
 1.3
0.2
 -2.4
 8.1
 9.1
4.4
 1.2
-1.3
 0.1
-1.8
 7.6
2.6
 4.5
1.8
 2.5
0.5
 3.9
1.9
 1.8
-2.3
 5.6
1.4
 -1.6
 4.3
 0.5
 -0.4

4 per1b period circadian clock 1b 406204 10.9 5.7
10.1
4.7
 1.5
0.3
 4.8
-2.9
 2.0
1.0
 9.1
6.8
 9.9
8.4
 4.1
1.3
 4.5
1.0
 8.9
5.8
 3.0
1.6
 4.1
0.1
 5.0
4.3
 1.3
0.9
 6.1
3.6
 0.4
0.3
 4.8
3.5
 0.9
 0.5
0.9
0.2
5 cry5 cryptochrome circadian regulator 5 83776 10.8 5.4
 4.5
 10.5
9.3
 8.9
3.2
 8.9
6.4
 2.0
 2.0
 2.4
 2.4
 2.5
 2.5
 3.8
2.9
 4.9
2.9
 4.9
3.8
 -0.1
 -0.1
 -1.1
 -1.1
 -1.1
 -1.1

6 nr1d2b nuclear receptor subfamily 1, group D, member 2b 30271 10.2 5.8
 3.5
 5.0
1.8
 2.6
0.5
 0.5
0.2
 1.1
-0.9
 4.6
4.3
 7.1
4.9
 -2.0
-5.1
 -5.4
-9.1
 6.0
3.8
 2.1
2.1
 0.2
-0.5
 3.8
2.5
 0.9
0.1
 4.3
4.0
 -0.8
-1.4
 2.9
2.3
 -1.0
-1.1
 0.8
-0.2

7 ddb2 damage-specific DNA binding protein 2 100004133 10.1 5.2
 4.0
 8.9
 -0.9
 0.9
 -1.1
 0.1
 1.3
 1.2
 1.0
 0.5
 -0.1
 0.9
 1.2
 0.1
 -0.3
 -1.1
 1.4


0.0
8 cry-dash cryptochrome DASH 402986 9.6 4.9
 3.8
 10.5
9.3
 8.9
3.2
 8.9
6.4
 2.0
 2.0
 2.4
 2.4
 2.5
 2.5
 3.8
2.9
 4.9
2.9
 4.9
3.8
 -0.1
 -0.1
 -1.1
 -1.1
 -1.1
 -1.1

9 nr1d1 nuclear receptor subfamily 1, group d, member 1 494487 9.4 4.9
5.0
1.8
 2.6
0.5
 0.5
0.2
 1.1
-0.9
 4.6
4.3
 7.1
4.9
 -2.0
-5.1
 -5.4
-9.1
 6.0
3.8
 2.1
2.1
 0.2
-0.5
 3.8
2.5
 0.9
0.1
 4.3
4.0
 -0.8
-1.4
 2.9
2.3
 -1.0
-1.1
 0.8
-0.2

10 lonrf1 LON peptidase N-terminal domain and ring finger 1 560773 9.4 4.5
 4.1
 7.8
6.1
 2.7
1.8
 4.5
2.8
 4.1
0.6
 1.2
0.2
 4.5
0.1
 6.7
3.7
 8.3
3.9
 3.8
0.7
 2.8
2.0
 3.2
3.0
 4.9
1.5
 1.3
0.6
 0.8
0.5
 2.0
1.9
 0.5
0.1
 -1.1
 -0.3
0.4
11 wdr76 WD repeat domain 76 570063 9.0 4.2
 4.0
 6.5
 0.3
 3.8
 0.4
 -0.9
 -1.0
 0.7
 0.8
 0.9
 0.9
 0.8
 -1.3
 1.4
 -1.0
 -0.6
 -0.4

0.8
12 si:dkey-18a10.3 si:dkey-18a10.3 792628 8.8 4.6
5.5
5.4
 -0.3
-0.9
 2.1
-3.3
 2.8
0.6
 3.0
1.7
 1.1
0.4
 1.9
0.9
 2.4
0.7
 1.8
1.1
 1.4
0.2
 2.1
1.1
 2.8
1.4
 2.6
1.8
 3.9
0.2
 2.6
-0.1
 0.3
-1.2
 -0.3
 2.2
 -0.1
13 cry1b cryptochrome circadian regulator 1b 554836 7.9 4.1
 3.2
 10.5
9.3
 8.9
3.2
 8.9
6.4
 2.0
 2.0
 2.4
 2.4
 2.5
 2.5
 3.8
2.9
 4.9
2.9
 4.9
3.8
 -0.1
 -0.1
 -1.1
 -1.1
 -1.1
 -1.1

14 hsf2 heat shock transcription factor 2 140427 7.6 4.5
 2.5
 5.5
5.4
 -0.3
-0.9
 2.1
-3.3
 2.8
0.6
 3.0
1.7
 1.1
0.4
 1.9
0.9
 2.4
0.7
 1.8
1.1
 1.4
0.2
 2.1
1.1
 2.8
1.4
 2.6
1.8
 3.9
0.2
 2.6
-0.1
 0.3
-1.2
 -0.3
 2.2
 -0.1
15 cry2 cryptochrome circadian regulator 2 83774 7.6 4.2
 2.8
 10.5
9.3
 8.9
3.2
 8.9
6.4
 2.0
 2.0
 2.4
 2.4
 2.5
 2.5
 3.8
2.9
 4.9
2.9
 4.9
3.8
 -0.1
 -0.1
 -1.1
 -1.1
 -1.1
 -1.1

16 si:ch1073-390k14.1 si:ch1073-390k14.1 101883856 7.0 3.6
10.5
9.3
 8.9
3.2
 8.9
6.4
 2.0
 2.0
 2.4
 2.4
 2.5
 2.5
 3.8
2.9
 4.9
2.9
 4.9
3.8
 -0.1
 -0.1
 -1.1
 -1.1
 -1.1
 -1.1

17 si:dkey-104n9.1 si:dkey-104n9.1 560366 6.6 3.4




















18 abhd4 abhydrolase domain containing 4, N-acyl phospholipase B 550276 6.5 3.6
 2.3
 6.1
0.7
 0.9
-0.5
 3.5
0.4
 1.6
0.4
 0.8
-0.3
 -0.4
-0.6
 1.7
-1.4
 0.7
-0.6
 0.9
-0.7
 1.4
 0.7
 0.5
 3.1
-0.2
 0.8
-0.8
 0.8
0.2
 -0.2
-0.9
 0.0
 -0.4
 3.6
-0.9
19 si:ch1073-440b2.1 si:ch1073-440b2.1 100000190 6.4 3.3
7.8
6.1
 2.7
1.8
 4.5
2.8
 4.1
0.6
 1.2
0.2
 4.5
0.1
 6.7
3.7
 8.3
3.9
 3.8
0.7
 2.8
2.0
 3.2
3.0
 4.9
1.5
 1.3
0.6
 0.8
0.5
 2.0
1.9
 0.5
0.1
 -1.1
 -0.3
0.4
20 abhd2a abhydrolase domain containing 2, acylglycerol lipase a 393888 6.3 2.1
 3.7
 3.1
-0.4
 0.7
-0.8
 -0.5
-2.1
 0.2
 0.9
 0.9
 -0.2
 -0.5
 0.2
 -1.1
 -0.5
 -0.3
 -0.1
 0.1
 -1.5
 -0.2
 1.9
 -0.7
3.3
21 si:ch211-225b11.1 si:ch211-225b11.1 561694 6.2 3.2




















22 dhrs12 dehydrogenase/reductase (SDR family) member 12 556393 6.1 3.4
 2.2
 6.2
0.4
 0.0
-0.7
 1.6
0.1
 -0.4
 2.5



1.9
 -0.4
 0.6







23 per3 period circadian clock 3 58107 5.9 3.9
 1.5
 10.1
4.7
 1.5
0.3
 4.8
-2.9
 2.0
1.0
 9.1
6.8
 9.9
8.4
 4.1
1.3
 4.5
1.0
 8.9
5.8
 3.0
1.6
 4.1
0.1
 5.0
4.3
 1.3
0.9
 6.1
3.6
 0.4
0.3
 4.8
3.5
 0.9
 0.5
0.9
0.2
24 nfil3-6 nuclear factor, interleukin 3 regulated, member 6 431765 5.8 2.8
 2.6



















25 sik2b salt-inducible kinase 2b 567919 5.7 3.4
 1.9
 1.8
1.6
 -0.4
-1.0
 0.4
-0.6
 1.1
 3.6
 3.7
 1.1

1.1
 1.9
 3.2
 2.7
 2.4
 -0.1
 2.1
 -0.6
 0.6

26 bhlhe40 basic helix-loop-helix family, member e40 324413 5.6 3.1
 2.1
 2.2
 -2.4
 -2.2
 0.9
 1.8
 2.9
 0.7
 -0.6
 2.0
 0.6
 0.8
 1.1
 -0.8
 0.5
 0.4
 2.5



27 per1a period circadian clock 1a 563926 5.6 3.0
10.1
4.7
 1.5
0.3
 4.8
-2.9
 2.0
1.0
 9.1
6.8
 9.9
8.4
 4.1
1.3
 4.5
1.0
 8.9
5.8
 3.0
1.6
 4.1
0.1
 5.0
4.3
 1.3
0.9
 6.1
3.6
 0.4
0.3
 4.8
3.5
 0.9
 0.5
0.9
0.2
28 amd1 adenosylmethionine decarboxylase 1 792097 5.6 2.9
3.0
 -3.9
 -1.2
 2.2
 -0.8
 0.4
 1.1
 1.3
 0.3
 -0.7
 0.8
 0.3
 2.3
 -0.7
 2.0
 -0.6
 0.6
 0.0
 -0.2
 0.9
29 si:ch211-132b12.7 si:ch211-132b12.7 564531 5.5 2.9




















30 msrb3 methionine sulfoxide reductase B3 415184 5.5 2.8
 2.3
 2.1
-1.2
 0.0
-0.1
 1.8
0.4
 1.3
-2.3
 -0.2
-0.8

-0.1
 1.0
 0.2
 1.0
 -1.0
 0.6
-0.6
 1.6
-0.6
 1.0
0.1
 0.4
0.1
 -0.1
 0.6
 -0.7
31 znf395b zinc finger protein 395b 566703 5.5 3.5
 1.5
 4.1
1.7
 0.8
-0.1
 -0.6
-1.0
 1.5
-0.9
 1.9
1.4
 2.1
-0.3
 -0.2
-1.8
 2.1
0.2
 0.6
0.1
 1.2
0.9
 1.3
0.9
 1.3
0.5
 1.4
-0.2
 3.6
1.6
 0.6
0.2
 0.7
-0.0



32 ercc6 excision repair cross-complementation group 6 560477 5.4 2.8
3.0
 1.0
 3.3
 -1.3
 0.8
 0.7
 0.3
 0.6
 2.7
 -0.6
 0.8
 -0.5
 0.6
 -0.5
 0.3
 0.2

0.3
33 tefb TEF transcription factor, PAR bZIP family member b 553686 5.3 3.2
 1.7
 7.1
3.5
 3.6
1.5
 1.3
0.2
 -2.4
 8.1
 9.1
4.4
 1.2
-1.3
 0.1
-1.8
 7.6
2.6
 4.5
1.8
 2.5
0.5
 3.9
1.9
 1.8
-2.3
 5.6
1.4
 -1.6
 4.3
 0.5
 -0.4

34 tmem106ba transmembrane protein 106Ba 393333 5.3 3.4
 1.4



















35 dbpa D site albumin promoter binding protein a 565056 5.3 2.8
7.1
3.5
 3.6
1.5
 1.3
0.2
 -2.4
 8.1
 9.1
4.4
 1.2
-1.3
 0.1
-1.8
 7.6
2.6
 4.5
1.8
 2.5
0.5
 3.9
1.9
 1.8
-2.3
 5.6
1.4
 -1.6
 4.3
 0.5
 -0.4

36 fbxo33 F-box protein 33 567750 5.3 2.8
3.9
 -0.7
 1.5
 2.2
 2.3
 1.0
 1.0
 1.5
 0.3
 0.5
 0.5
 -0.8
 2.9
 0.7
 -0.5
 -0.3
 -0.4
 1.0

37 ciarta circadian associated repressor of transcription a 564009 5.2 3.4
 1.4
 3.1
 -3.0
 -8.1
 0.2
 4.3
 7.7
 1.0
 -1.3
 5.9
 0.4
 -1.6
 -0.6
 0.1
 3.0
 1.0
 1.0



38 atf6b activating transcription factor 6 beta 777612 5.2 2.7
4.5
1.9
 2.1
-2.8
 -0.2
-0.8
 0.6
-2.4
 -0.1
-0.9
 0.9
-0.2
 1.2
0.5
 0.3
-0.4
 0.3
-0.4
 0.5
 -0.8
 -1.2
 -0.4
-0.6
 -0.0
-1.1
 1.1
1.0
 0.6
-0.1
 -1.3
 -0.2
0.7
0.6
39 selenoj selenoprotein J 572182 5.1 2.7




















40 neil1 nei-like DNA glycosylase 1 393253 4.9 2.3
 2.3
 3.3
 0.6
 3.1

-1.3
 -0.5
 -1.6
 -0.9
 1.8
 -0.6
 0.6
 -0.9
 1.9
 -0.8
 0.8



41 mylipb myosin regulatory light chain interacting protein b 565911 4.8 2.5
2.4
1.4
 -0.7
-2.2
 0.2
-2.4
 1.0
 1.4
 0.7
 -0.8
 -0.7
 1.5
 -0.1
 0.7
 0.6
 1.3
 0.6
 1.6
 -0.2
 -0.5
 1.4

42 si:dkey-106l3.6 si:dkey-106l3.6 100526811 4.7 2.5
1.1
 -1.8
 -0.6
 -1.6
 -0.6
 1.0
 -1.1
 -0.1
 0.1
 0.9
 -1.0
 -0.6







43 mat2ab methionine adenosyltransferase II, alpha b 791612 4.7 2.5
2.4
1.6
 0.4
-1.5
 -0.3
-0.8
 1.3
-0.3
 -0.1
-0.9
 0.6
0.4
 0.8
0.4
 0.1
0.1
 1.1
0.8
 1.7
1.3
 1.2
0.2
 1.3
0.4
 1.5
1.0
 0.2
-0.3
 1.6
-0.2
 0.3
0.2
 -0.2
 0.2
 0.7
0.2
44 cipca CLOCK-interacting pacemaker a 100535864 4.7 2.5
4.2
3.7
 -2.1
-2.8
 -5.0
-6.0
 1.0
 2.7
 3.5
 2.6
 0.9
 2.3
 -0.2
 -0.5
 0.2
 2.1
 3.0
 -0.3
 1.3



45 hmox2a heme oxygenase 2a 100002875 4.6 2.4
3.1
-0.1
 0.5
0.5
 3.4
2.9
 1.0
0.6
 0.9
0.6
 0.4
-0.5
 0.7
-1.1
 1.2
1.2
 1.3
-0.4
 -0.4
-1.3
 -0.1
-1.9
 1.5
-0.9
 1.2
-1.8
 2.6
-0.8
 -0.9
-1.1
 0.1
-2.0
 -0.8
 -1.3
 -0.5
46 LOC571902 uncharacterized LOC571902 571902 4.6 2.4




















47 ubxn2a UBX domain protein 2A 100537478 4.6 2.4
2.2
 0.4
 2.2
 2.3
 -0.7
 0.5
 1.0
 1.1
 -0.3
 -0.2
 0.8
 0.1
 3.3
 0.1
 0.3
 -0.4



48 si:ch211-161h7.5 si:ch211-161h7.5 569866 4.6 1.8
 2.4
 4.1
0.1
 0.9
-0.2
 0.9





1.7
 -0.2
 0.3







49 rbm39a RNA binding motif protein 39a 406251 4.6 1.7
 2.5
 0.8
-0.5
 3.4
2.0
 3.6
0.4
 1.6
1.2
 1.3
0.5
 0.5
 1.0
 0.4
 0.7
 -0.9
 3.8
 2.6
 1.1
0.7
 2.5
-0.8
 1.7
-0.1
 0.9
0.6
 -0.2
 1.4

50 cbr1 carbonyl reductase 1 373866 4.5 2.4
4.1
-0.2
 2.0
0.8
 2.1
0.8
 -0.2
-0.3
 -1.4
-1.6
 0.5
0.2
 0.3
-0.2
 1.1
0.3
 0.3
-0.1
 1.3
 0.4
 0.1
 -0.5
-1.6
 1.0
0.3
 0.3
-0.2
 0.6
-0.7



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