Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-m.7   RSPO2   R-spondin 2 
 hsa-u.4   RSPO2   R-spondin 2 
 hsa-r.6   RSPO2   R-spondin 2 
 hsa-m2.4   RSPO2   R-spondin 2 
 mcc-u.3   RSPO2   R-spondin 2 
 mmu-u.4   Rspo2   R-spondin 2 
 rno-u.3   Rspo2   R-spondin 2 
 cfa-u.3   RSPO2   R-spondin 2 
 gga-u.3   RSPO2   R-spondin 2 
 dre-u.3   rspo2   R-spondin 2 

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Top 50 coexpressed genes to RSPO2 (hsa-m.7 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4080   Neuroactive ligand-receptor interaction  7 189 7.07
 hsa5033   Nicotine addiction  4 28 5.85
 hsa4723   Retrograde endocannabinoid signaling  3 125 3.27
 hsa4020   Calcium signaling pathway  3 240 -
 hsa5010   Alzheimer disease  3 384 -

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hsa:RSPO2 (R-spondin 2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-m.7
for
RSPO2
hsa-u.4
for
RSPO2
hsa-r.6
for
RSPO2
hsa-m2.4
for
RSPO2
mcc-u.3
for
RSPO2
mmu-u.4
for
Rspo2
rno-u.3
for
Rspo2
cfa-u.3
for
RSPO2
gga-u.3
for
RSPO2
dre-u.3
for
rspo2
1 OLFM3 olfactomedin 3 118427 0 4.5 4.7
 4.1
 4.2
 3.5
2.1
 1.5
1.4
 2.2
1.2
 1.3
1.2
 1.6
1.0
 1.7
1.3
2 LGI1 leucine rich glioma inactivated 1 9211 0 4.2 4.0
 3.5
 3.4
 2.8
 2.0
 3.2
0.7
 0.4
3 MAB21L2 mab-21 like 2 10586 0 4.0 4.7
 2.2
 6.1
 2.6
0.5
 4.2
2.9
 0.1
-0.4
 0.4
-0.3
 1.4
0.3
 2.2
1.5
4 EPHA7 EPH receptor A7 2045 0 3.6 4.1
 4.2
 3.1
 3.4
2.6
 4.9
4.0
 3.5
2.4
 2.0
1.6
 1.7
1.3
 3.1
2.6
5 LOC100509968 uncharacterized LOC100509968 100509968 0 3.5








6 HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 54511 0 3.4

3.2
 1.5
-2.0
 1.9
-0.6
 0.6
-0.8
 -1.7
 0.5
-1.3
 -0.7
7 C11orf87 chromosome 11 open reading frame 87 399947 0 3.4 2.4
 1.8
 2.5
 0.3
 1.9
 0.5


8 TCF21 transcription factor 21 6943 0 3.3 3.6
 4.0
 2.2
 1.5
-0.2
 -1.2
 -0.5
 0.7
0.3
 2.3
0.6
 -0.2
9 PDZRN4 PDZ domain containing ring finger 4 29951 0 3.3 3.1
 2.9
 2.6
 4.2
1.4
 2.1
1.9
 1.0
0.1
 2.5
0.9
 0.8
0.5
 2.1
1.7
10 VSTM2A-OT1 VSTM2A overlapping transcript 1 285878 0 3.3








11 UNC13C unc-13 homolog C 440279 0 3.2 2.6
 1.4
 3.1
 3.8
-0.8
 1.4
1.2
 1.7
1.2
 -0.7
-1.3
 1.2
0.6
 1.2
-0.6
12 CNTN5 contactin 5 53942 0 3.1

4.3
 3.9
2.7
 3.5
3.2
 0.8
0.6
 1.4
1.2
 1.4
0.9
 0.6
0.4
13 DACH2 dachshund family transcription factor 2 117154 0 3.1

2.3
 1.1
-0.1
 -0.3
 0.4
0.0
 0.1
 1.3
0.4
 2.2
2.0
14 NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 10003 0 3.1 2.5
 1.4
 3.1
 1.2
0.6
 1.0
0.6
 1.1
-0.5
 0.4
0.4
 0.2
0.1
 0.6
0.1
15 HAPLN1 hyaluronan and proteoglycan link protein 1 1404 0 3.1 2.3
 2.9
 1.2
 1.9
 2.4
 1.4
 2.3
 0.8
 0.6
16 LHX8 LIM homeobox 8 431707 0 3.0

1.5
 1.3
 2.5
1.1
 1.6
 1.3
1.2
 1.3
0.7
 2.3
1.4
17 CPXCR1 CPX chromosome region candidate 1 53336 0 3.0

0.5





18 GREM2 gremlin 2, DAN family BMP antagonist 64388 0 2.9 3.4
 2.3
 3.7
 3.2
1.0
 3.5
2.9
 2.3
0.8
 -0.0
 2.1
0.9
 4.2
19 SLC39A12 solute carrier family 39 member 12 221074 0 2.9 3.8
 3.2
 3.6
 3.4
 1.0
 0.5
 0.8
 0.7
20 SERTM1 serine rich and transmembrane domain containing 1 400120 0 2.9 2.9
 3.5
 1.6
1.6
 2.7
-0.1
21 LINC02877 long intergenic non-protein coding RNA 2877 152118 0 2.9

1.2





22 LRRTM4 leucine rich repeat transmembrane neuronal 4 80059 0 2.9

3.6
 2.5
 2.5
 1.1
1.2
 -0.9
23 GABRA2 gamma-aminobutyric acid type A receptor subunit alpha2 2555 0 2.8

3.3
 2.5
2.5
 3.1
2.9
 4.1
1.3
 0.5
0.3
 2.1
1.2
 0.2
0.1
24 LMO3 LIM domain only 3 55885 0 2.8 3.9
 2.9
 3.9
 2.8
0.2
 3.6
1.3
 1.1
 -0.2
-0.6
 2.5
1.7
 1.4
1.2
25 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2903 0 2.8 2.7
 2.0
 2.8
 4.1
1.8
 2.5
2.3
 3.0
0.7
 1.2
1.0
 1.2
0.5
 0.6
0.1
26 OPRK1 opioid receptor kappa 1 4986 0 2.8 2.8
 2.1
 2.8
 -1.1
 2.3
 0.3


27 CDC14C cell division cycle 14C 168448 0 2.8

2.5
 -1.2
-1.4
 -0.7
-0.7
 -0.7
 0.3
-0.6
 0.5
-0.2
 1.2
1.1
28 GRIA4 glutamate ionotropic receptor AMPA type subunit 4 2893 0 2.8 2.8
 2.3
 2.6
 3.9
3.2
 1.9
1.4
 1.5
0.3
 3.8
2.3
 1.9
1.7
 1.0
0.9
29 TMEM35A transmembrane protein 35A 59353 0 2.8 2.8
 2.2
 2.8
 1.4
 0.8
 0.5
 0.1
 1.6
 1.7
30 BMP5 bone morphogenetic protein 5 653 0 2.7 3.7
 3.7
 2.8
 3.2
1.5
 1.9
0.1
 2.1
1.6
 2.3
1.6
 0.1
-0.4
 4.3
2.0
31 LIX1 limb and CNS expressed 1 167410 0 2.7 3.4
 2.9
 3.1
2.9
 1.0

2.6
32 RXFP1 relaxin family peptide receptor 1 59350 0 2.7

2.7
3.5
 0.4
1.5
0.3
 0.5
-0.2
33 NDNF neuron derived neurotrophic factor 79625 0 2.7 3.5
 3.2
 2.9
 1.6
 3.4
 0.2
 2.5
 1.6
 2.7
34 CTXN3 cortexin 3 613212 0 2.7

2.8
1.0
 -0.5

-2.2
35 BRINP3 BMP/retinoic acid inducible neural specific 3 339479 0 2.6

3.0
 2.8
 2.5
 -0.0
0.7
 1.0
0.4
36 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 133121 0 2.6 2.9
 1.7
 3.3
 1.6
 -1.8
 -0.9
 1.5
 1.1
 1.0
37 SLC25A31 solute carrier family 25 member 31 83447 0 2.6

1.8
 -0.4
-0.7
 0.8
-0.7
 0.4
-0.6
 -0.6
-1.0
 0.0
-0.6
 0.7
0.6
38 CA10 carbonic anhydrase 10 56934 0 2.6 3.1
 3.0
 2.4
 2.1
-0.7
 4.2
0.6
 1.6
-0.3
 2.3
0.5
 1.3
 0.7
0.6
39 LOC149351 uncharacterized LOC149351 149351 0 2.6








40 NKAIN3-IT1 NKAIN3 intronic transcript 643763 0 2.6

2.4





41 SLC13A1 solute carrier family 13 member 1 6561 0 2.6

1.5
 1.4
1.1
 0.5
0.1
 1.7
-0.3
 0.3
-0.1
 0.8
0.7
 2.1
0.8
42 VSTM2A V-set and transmembrane domain containing 2A 222008 0 2.6

2.3
 2.0
 1.5
 1.5
0.6
 0.5
43 GABRA1 gamma-aminobutyric acid type A receptor subunit alpha1 2554 0 2.6 2.9
 2.7
 2.4
 2.5
2.5
 3.1
2.9
 4.1
1.3
 0.5
0.3
 2.1
1.2
 0.2
0.1
44 ADGRB3 adhesion G protein-coupled receptor B3 577 0 2.5 2.5
 2.2
 2.2
 2.3
 1.2
 0.5
 2.0
 1.4
 -0.6
45 PPP4R3C protein phosphatase 4 regulatory subunit 3C 139420 0 2.5

0.3
 -0.6
-1.3
 -0.4
-0.9
 -0.4
-1.4
 -0.8
-0.8
 -0.2
-1.1
 0.2
-0.2
46 LOC403312 putative uncharacterized protein MGC39545 403312 0 2.5








47 EPHA3 EPH receptor A3 2042 0 2.5 2.4
 1.9
 2.3
 3.4
2.6
 4.9
4.0
 3.5
2.4
 2.0
1.6
 1.7
1.3
 3.1
2.6
48 HTR2A 5-hydroxytryptamine receptor 2A 3356 0 2.5 4.4
 4.3
 3.4
2.4
1.4
 0.5
-0.1
1.0
0.7
49 LINC02433 long intergenic non-protein coding RNA 2433 340017 0 2.5








50 PRDM6 PR/SET domain 6 93166 0 2.5

4.8
 2.9
1.6
1.8
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