Orthologous genes in OrthoFinder**

Species Gene Description
 cfa-m.4  PFKFB1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 cfa-u.3  PFKFB1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 cfa-r.3  PFKFB1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 cfa-u.3  PFKFB4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 cfa-u.3  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 cfa-u.3  PFKFB3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 hsa-u.4  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 hsa-u.4  PFKFB3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 mmu-u.4  Pfkfb2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mmu-u.4  Pfkfb1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 mmu-u.4  Pfkfb4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 rno-u.3  Pfkfb3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 rno-u.3  Pfkfb2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mcc-u.3  PFKFB4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 mcc-u.3  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mcc-u.3  PFKFB3  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 gga-u.3  PFKFB4  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 gga-u.3  PFKFB1  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 gga-u.3  PFKFB2  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 dre-u.3  pfkfb2b  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b 
 dre-u.3  pfkfb4a  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a 
 dme-u.3  Pfrx  6-phosphofructo-2-kinase 
 cel-u.3  pfkb-1.1  6-phosphofructo-2-kinase 
 cel-u.3  pfkb-1.2  Fructose-2,6-bisphosphatase 
 sce-u.3  YLR345W  bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase 
 sce-u.3  FBP26  fructose-2,6-bisphosphatase 

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Top 50 coexpressed genes to PFKFB1 (cfa-m.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 cfa3320   PPAR signaling pathway  5 69 7.05
 cfa4920   Adipocytokine signaling pathway  3 62 4.32
 cfa4152   AMPK signaling pathway  3 113 3.31
 cfa4068   FoxO signaling pathway  3 127 -
 cfa4151   PI3K-Akt signaling pathway  3 359 -

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cfa:PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID LINK Target Reference

cfa-m.4
for
PFKFB1


cfa-u.3
for
PFKFB1


cfa-r.3
for
PFKFB1


cfa-u.3
for
PFKFB4


cfa-u.3
for
PFKFB2


cfa-u.3
for
PFKFB3


hsa-u.4
for
PFKFB2


hsa-u.4
for
PFKFB3


mmu-u.4
for
Pfkfb2


mmu-u.4
for
Pfkfb1


mmu-u.4
for
Pfkfb4


rno-u.3
for
Pfkfb3


rno-u.3
for
Pfkfb2


mcc-u.3
for
PFKFB4


mcc-u.3
for
PFKFB2


mcc-u.3
for
PFKFB3


gga-u.3
for
PFKFB4


gga-u.3
for
PFKFB1


gga-u.3
for
PFKFB2


dre-u.3
for
pfkfb2b


dre-u.3
for
pfkfb4a


dme-u.3
for
Pfrx


cel-u.3
for
pfkb-1.1


cel-u.3
for
pfkb-1.2


sce-u.3
for
YLR345W


sce-u.3
for
FBP26

1 GPD1 glycerol-3-phosphate dehydrogenase 1 607942 5.3 6.6
2.0
1.4
0.3
1.2
-0.1
1.2
-1.4
1.6
0.6
0.3
-0.4
1.5
-0.4
1.4
-0.0
0.6
-0.1
2.2
1.8
2.0
-1.3
-2.1
1.9
0.4
3.8
0.9
1.2
1.0
0.8
-0.0
0.5
0.4
0.9
0.6
3.1
-1.3
2.0
-1.7
3.4
-1.7
0.4
-1.1
-1.1
-1.2
2 AQP7 aquaporin 7 474742 5.0 5.2
1.0
-0.4
1.1
1.0
0.7
0.6



0.5
0.4
0.8
0.6
-1.4










3 ADIPOQ adiponectin, C1Q and collagen domain containing 403625 4.7 6.7
2.6
0.9
-0.0
1.7
-0.6
0.6
-1.0
1.9
0.5
0.9
0.0
-2.2
-1.0
-0.5
-0.1
0.0
-0.2







4 AGMO alkylglycerol monooxygenase 475247 4.4




0.2
0.1
0.7
0.3
-0.7
-0.9
-0.3



-2.4
-0.4
1.1
0.9
0.1

-0.3
0.5


5 TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 491186 4.4




-1.1
0.3
-1.0
2.0
-0.2
2.8
0.2
-0.6
-0.4
-1.0
-1.6
0.5
-0.3
-1.4
0.0





6 CIDEC cell death inducing DFFA like effector c 484662 4.2 6.6
2.9
0.5
0.1
-0.3
-0.6
2.2
1.2
-0.6
-1.1
0.5
-0.2
0.5
0.3
2.8
0.6
0.5
0.1
1.5
0.3
0.1
-0.5
-0.3
-0.8
0.4
0.2
-0.5
-0.5
3.5
1.1
1.2
-0.1
-0.3
-1.2
-0.4
-0.4
1.5
0.1
0.0
-0.1




7 WDR88 WD repeat domain 88 476494 4.1



















-0.5




8 GRIA4 glutamate ionotropic receptor AMPA type subunit 4 489427 3.9

0.5
-0.7
0.5
-0.5
0.5
0.3
0.2
-0.1
0.1
-0.4
1.1
0.6
-0.6
-0.8
-0.3
-0.6
0.6
-0.1
0.4
-0.2
1.6
-0.4
-0.2
-0.6
1.4
0.3
0.6
0.4
0.0
-0.1
0.6
0.1
1.8
1.7
0.9
0.1
0.2
-0.7
-1.4
-0.7


9 APOC3 apolipoprotein C3 442970 3.9 6.0
2.5
0.3
-0.3
0.4
-1.7
-1.6
-1.3
0.9
-0.3
-0.1
-0.5
0.7
-1.4
-1.5
-0.2
-0.1
-0.5







10 PLIN4 perilipin 4 491467 3.6 4.5
1.4
1.1
1.3
1.6
1.1
1.6
1.1
2.7
-0.4
2.6
0.1
-1.7
-0.2
-0.5










11 SLC22A1 solute carrier family 22 member 1 484068 3.6 5.6
2.4
1.0
1.0
1.8
1.5
1.8
0.6
3.5
2.0
0.8
0.6
2.4
0.7
2.7
1.0
1.5
1.5
1.0
0.9
1.1
1.1
3.2
1.1
0.5
0.3
1.6
0.9
2.6
1.3
1.0
0.9
1.3
1.1
1.6
1.1
1.1
1.0
1.7
1.6
2.3
1.9
2.3
1.4


12 PROC protein C, inactivator of coagulation factors Va and VIIIa 476104 3.6 2.7
-0.2
-0.3
0.0
-0.1
-0.9
-0.6
-0.1
0.4
-0.9
-0.1
-0.9
-0.4
0.9
0.1
-1.0
0.9
-0.0
0.7
0.4





13 MTARC1 mitochondrial amidoxime reducing component 1 488601 3.6 5.3
2.2
-0.4
-1.3
0.2
-0.8
1.1
-1.4
1.8
1.4
0.2
-0.2
0.1
-1.2
3.1
0.4
-0.6
-0.7
0.3
-0.9
-1.1
-1.5
2.4
-0.6
0.2
-0.2
0.1
0.1
-2.4
0.9
0.6
0.8
-0.4
0.1
0.4
0.3
1.6
0.8


14 G6PC1 glucose-6-phosphatase catalytic subunit 1 403492 3.5 4.8
1.8
1.4
0.1
0.0
-0.2
0.9
0.2
-0.6
-0.8
-0.5
-1.0
-0.3
-0.5
0.3
0.2
0.9
-0.2
-0.0
-0.5
0.1
0.0
0.7
-0.6
-1.0
-1.2
0.4
-0.6
0.5
0.1
1.0
0.1
0.3
-0.3
-0.4
-0.5
-0.3
-0.4
-0.6




15 ACVR1C activin A receptor type 1C 488361 3.5 4.5
1.5
1.2
0.2
0.7
0.3
1.2
0.5
2.3
2.0
2.8
1.7
1.3
0.5
1.5
-0.1
2.8
2.5
4.5
1.5
1.6
1.3
1.5
0.4
1.7
0.2
1.3
0.5
2.6
1.1
1.1
0.5
0.6
0.4
1.8
0.7
2.2
1.4
1.5
0.3
1.9
0.6
0.3
-0.3


16 PLIN1 perilipin 1 488735 3.5
























17 TMEM52 transmembrane protein 52 607284 3.4




-0.2
0.5
-0.2
0.4
0.8
1.7
0.8
-0.8
-0.5
0.2
1.8
1.4
1.3







18 FMO3 flavin containing dimethylaniline monoxygenase 3 403603 3.4 4.0
1.2
1.9
0.1
0.7
0.6
1.3
1.2
1.6
1.5
0.0
-0.2
2.0
0.3
2.8
2.1
1.5
-0.6
0.4
-0.1
0.7
0.6
0.5
-0.7
1.8
0.3
0.2
-0.6
-1.2
1.0
-0.3
1.2
0.3
0.9
0.7
1.8
1.2
2.3
0.2
2.6
1.7
1.2
0.1
-0.5
0.6
19 KLB klotho beta 479110 3.3




-1.6
-0.1
-1.5
2.8
-1.3
0.2
-0.5
-0.5
-0.6
-0.0
-0.7
0.1
0.3
-0.4
1.6





20 RHBG Rh family B glycoprotein 403538 3.3 3.9
1.1
1.8
0.2
1.2
1.2
0.4
0.2
0.9
-0.5
0.8
-0.2
0.3
0.3
0.5
0.4
0.9
0.6
1.1
1.0
0.7
0.0
0.1
-0.1
2.4
-1.2
1.1
0.1
0.3
-0.1
0.3
-0.3
0.4
0.4
1.4
0.9
0.2
0.2
-0.1
1.0
-0.5
1.0
0.5


21 TMEM182 transmembrane protein 182 611413 3.2 6.0
3.0
-0.0
-0.7
1.1


-0.6
1.7
-0.2
-0.2
0.3



-0.2
0.1
0.4
1.4
0.7





22 TENM2 teneurin transmembrane protein 2 489135 3.2 3.9
1.3
0.6
0.0
0.5
-0.2
1.0
0.9
-0.3
-0.7
0.5
0.4
-0.5
-0.6
0.8
-0.1
0.4
0.1
0.6
-0.5
-0.2
-0.5
-0.0
-0.2
0.6
-0.2
0.8
-0.4
1.7
1.5
0.4
-0.6
0.8
-0.3
0.6
0.4
0.2
-0.0
0.9
0.1
-0.3
-0.2


23 SHISAL2A shisa like 2A 609737 3.2
























24 LOC479668 haptoglobin-like 479668 3.2 5.4
2.6
-0.5
0.2
0.4
0.3
-0.3
0.9
0.1
-0.3
1.6
0.9
-0.1
-0.7
-0.4
-1.2
0.6
0.3
0.0
-0.9



0.2
-0.2





25 PNPLA2 patatin like phospholipase domain containing 2 611403 3.2 3.2
0.5
2.1
1.7
2.6
-0.4
0.9
-0.6
2.5
-0.1
0.8
-0.5
-0.1
-0.6
0.1
1.6
-1.9
1.5
1.0
1.4
-1.4
0.8
-1.4
1.8
1.2
2.8
2.4
0.2
1.8


26 CYYR1 cysteine and tyrosine rich 1 478395 3.1 4.1
1.5
0.4
-0.3
-0.4
0.8
0.1
-0.1
0.8
-1.4
-0.4
-0.9
-1.2
0.3
1.5
0.5
0.2
-2.0
-0.8
-2.7





27 ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 491368 3.1 3.7
1.1
-0.3
-0.4
-0.3
-0.6
-1.3
0.1
-0.5
0.0
-0.7
-0.5
-1.9
-1.1
0.0
0.2
-0.5
0.4
-0.0
-0.3
0.6
-0.4





28 PCK1 phosphoenolpyruvate carboxykinase 1 403560 3.1 6.2
3.4
0.5
-0.3
-0.4
-0.7
1.1
-0.3
0.1
0.0
1.0
-1.1
0.0
-1.3
2.6
-0.5
1.2
-1.0
0.5
-0.7
-0.3
-0.9
0.4
0.1
-0.3
-0.9
0.2
-1.7
0.9
0.5
0.4
-0.3
-1.0
0.2
-0.1
0.0
4.8
-0.1
-0.2
-0.8


29 TECRL trans-2,3-enoyl-CoA reductase like 475157 3.0 5.9
3.2
0.5
0.4
-0.1
-0.7
0.5
-0.3
-0.1
-1.2
-0.3
-0.5
0.8
-0.9
1.5
-0.8
0.3
-1.0
0.2
-1.7
0.4
-0.3
-0.9
-0.9
0.8
0.1
-0.1
2.2
0.7
0.6
-0.0
0.7
-0.3
-0.2
-0.6
0.8
1.2
0.8
-0.2
-1.1
30 LOC476047 solute carrier family 22 member 9 476047 3.0

1.0
1.0
1.8
1.5
1.8
0.6
3.5
2.0
0.8
0.6
2.4
0.7
2.7
1.0
1.5
1.5
1.0
0.9
1.1
1.1
3.2
1.1
0.5
0.3
1.6
0.9
2.6
1.3
1.0
0.9
1.3
1.1
1.6
1.1
1.1
1.0
1.7
1.6
2.3
1.9
2.3
1.4


31 APOC2 apolipoprotein C2 442969 3.0 3.2
0.7
-0.8
-0.3
-0.7





-0.6
-0.0
-1.4
0.4
-0.0
-1.0
0.7
-0.9
-0.0
0.4





32 ASB5 ankyrin repeat and SOCS box containing 5 482933 2.9 3.5
1.0
0.3
0.2
0.2
0.1
0.5
0.4
0.3
0.2
-0.3
-0.5
1.1
0.4
1.6
0.6
0.5
-0.1
1.4
-1.4
0.5
0.3
0.4
0.1
0.7
-0.5
-1.4
1.2
-0.4
0.4
-0.9
0.8
-0.1
0.1
-0.3

-0.4
0.7


33 DGAT2 diacylglycerol O-acyltransferase 2 485185 2.9 4.4
1.9
1.2
0.4
1.7
0.5
1.5
-0.2
0.2
1.4
0.2
-0.8
2.8
1.8
1.8
-0.0
2.1
0.8
0.2
-0.1
1.6
1.5
0.7
0.4
0.5
-0.1
1.2
0.4
1.9
0.9
1.1
0.7
0.6
0.6
1.5
-0.7
-0.7
-0.8
2.4
1.1
3.4
1.3
2.7
1.5
34 FFAR4 free fatty acid receptor 4 477774 2.9






-0.2
1.9
0.1


-0.0
-0.8
-2.3
-1.1
1.2
-1.2







35 NRXN1 neurexin 1 474589 2.8




-0.4
-0.4
0.4
0.1
-1.0
-1.4
-0.1
-0.8
-0.1
-0.5
0.8
-0.1
-0.3
-0.5
-0.6
-0.8
0.3
-0.0
-0.6
0.4
-0.5
1.2
1.1
-0.2
-1.2
0.5




36 ABCA6 ATP binding cassette subfamily A member 6 480456 2.8 3.4
1.0
0.0
-0.6
0.3
-0.2
-0.5
-1.3
0.6
0.3
-0.9
-1.3
1.7
1.5
1.5
1.3
0.5
-1.2
0.0
-1.1
0.4
-0.1
-0.4
-0.5
-0.4
-0.7
0.8
-0.0
3.2
0.8
1.7
1.2
0.4
-1.7


1.4
1.0
0.2
-0.5


37 CNST consortin, connexin sorting protein 611848 2.8 3.0
0.7
0.7
-0.6
1.6
2.3
0.3
1.8
0.4
1.0
0.9
1.0
0.4
1.2
0.2
-2.2
0.0
-0.1
0.6
0.6





38 MLXIPL MLX interacting protein like 489807 2.8 3.1
0.8
2.4
1.0
1.4
1.2
1.2
0.5
1.5
0.5
2.3
-0.1
0.8
0.2
2.7
1.4
1.5
-0.6
3.1
0.4
0.7
-0.2
1.1
0.2
-0.3
0.8
-0.5
1.8
-0.1
1.4
0.6
1.0
-0.5
-0.0
-0.7
0.2
-0.1
3.4
0.8
-0.7


39 SLC10A1 solute carrier family 10 member 1 480372 2.7 2.8
0.5
1.8
-0.9
-0.3
-2.5
-1.1
-1.8
-0.1
-0.9
-0.2
-0.5
1.1
0.8
1.5
0.7
0.4
-0.4
1.2
-0.7
1.0
-0.1
-0.3
-0.7
0.0
-0.3
0.2
0.0
-0.4
-1.7
-0.9
1.0
-0.7
-0.4




40 DHRS4 dehydrogenase/reductase 4 480254 2.7 2.8
0.6
0.5
0.1
1.1
0.2
0.6
0.1
2.4
-0.7
-0.2
-0.6
0.4
-1.0
1.4
0.1
-0.5
-1.1
0.2
-1.1
1.5
-0.5
0.3
-0.6
2.3
0.2
0.6
0.2
-0.9
1.1
-1.4
0.4
-0.4
1.6
-0.5
3.3
2.0
1.6
1.3
1.2
1.2
-0.2
-0.7
0.6
-0.5
41 CPED1 cadherin like and PC-esterase domain containing 1 475300 2.7 2.0
-0.1
-0.4
-0.7
-0.2
-0.3
-1.4
-0.2
1.5
-1.1
-1.4
-1.5
-0.9
0.1
-0.8
1.2
0.0
-0.6
0.3
0.4





42 PLAAT3 phospholipase A and acyltransferase 3 476045 2.7 3.4
1.1
-0.2
-0.8
1.4
-0.5
-0.6
0.8
-0.6
-1.3
0.9
-1.2
0.2
-1.8
-1.2
-3.0
-0.1
-1.5
0.0
-0.8



0.1
-0.2
0.2
-0.1





43 FMO1 flavin containing dimethylaniline monoxygenase 1 403604 2.7 3.0
0.8
1.9
0.1
0.7
0.6
1.3
1.2
1.6
1.5
0.0
-0.2
2.0
0.3
2.8
2.1
1.5
-0.6
0.4
-0.1
0.7
0.6
0.5
-0.7
1.8
0.3
0.2
-0.6
-1.2
1.0
-0.3
1.2
0.3
0.9
0.7
1.8
1.2
2.3
0.2
2.6
1.7
1.2
0.1
-0.5
0.6
44 LOC489851 cytochrome P450 3A12-like 489851 2.7

-0.4
2.0
-0.1
-0.6
-0.7
-0.9
-1.6
1.9
0.3
0.6
0.4
1.5
0.6
0.0
-0.5
-0.1
-0.2
1.6
0.8
-0.1
-0.2
0.5
-0.1
2.5
1.7
1.2
1.1
0.8
0.3
0.1
-0.1
1.8
1.1
2.6
2.5
2.0
1.6
2.1
2.0
-0.1
-1.3
45 CIDEA cell death inducing DFFA like effector a 490559 2.7 4.3
2.0
0.5
0.1
-0.3
-0.6
2.2
1.2
-0.6
-1.1
0.5
-0.2
0.5
0.3
2.8
0.6
0.5
0.1
1.5
0.3
0.1
-0.5
-0.3
-0.8
0.4
0.2
-0.5
-0.5
3.5
1.1
1.2
-0.1
-0.3
-1.2
-0.4
-0.4
1.5
0.1
0.0
-0.1




46 LOC483462 glycine N-phenylacetyltransferase-like 483462 2.6 2.6
0.4
-0.3
-0.4
0.5
0.3
-0.2
-1.2
0.2
-1.5
0.0
-0.4
-1.2
-1.7
1.0
0.7
-1.2
-1.4
-0.3
-0.5
0.3
-0.4
0.1
-1.1
1.3
-0.2
1.5
0.7



-0.6
0.1





47 LOC481865 similar to CG7245-PA 481865 2.6
























48 SGK2 serum/glucocorticoid regulated kinase 2 610835 2.6 3.1
0.9
0.1
-0.1
1.6
0.6
0.6
0.1
1.4
0.2
0.6
0.2
1.1
1.1
-0.4
-0.6
0.5
0.3
-0.1
-0.6
0.3
-0.0
2.3
0.7
1.4
0.6
1.8
1.4
1.5
0.4
-0.0
-0.1
-0.1
-0.3
0.7
0.5
0.7
0.5

0.0
-0.5
1.7
1.5
4.6
2.2
49 SLC38A3 solute carrier family 38 member 3 476617 2.6 2.0
-0.1
0.6
0.5
1.1
1.0
0.7
0.1
0.8
0.4
0.1
-0.3
1.1
0.9
2.4
1.4
1.3
-0.5
-0.1
-0.1
1.5
0.8
1.3
1.0
0.5
0.1
0.7
0.5
3.0
1.1
0.2
0.1
1.2
1.1
0.4
0.3
1.1
0.2





50 GYG2 glycogenin 2 491717 2.6 3.4
1.2
0.6
-1.0
0.7
-0.3
1.4
-0.9
1.7
0.1
-0.0
-0.5
-1.6
1.6
0.6
0.7
-1.9
0.7
-0.9
1.4
0.9
1.2
0.2
0.2
0.1
0.2
-1.1
1.1
-0.7
0.5
0.3
0.0
-0.5
2.8
1.4
1.3
0.7
0.0
3.3
2.4
2.6
1.0
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