Orthologous genes in OrthoFinder**

Species Gene Description
 fca-r.1   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 cfa-u.3   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 hsa-u.4   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 mmu-u.4   Letm1   leucine zipper-EF-hand containing transmembrane protein 1 
 rno-u.3   Letm1   leucine zipper and EF-hand containing transmembrane protein 1 
 mcc-u.3   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 gga-u.3   LETM1   leucine zipper and EF-hand containing transmembrane protein 1 
 dre-u.3   letm1   leucine zipper-EF-hand containing transmembrane protein 1 
 dme-u.3   Letm1   Leucine zipper and EF-hand containing transmembrane protein 1 
 cel-u.3   letm-1   LETM1 (Leucine zipper, EF-hand, TransMembrane mitochondrial protein) homolog 
 sce-u.3   YLH47   Ylh47p 
 sce-u.3   MDM38   ribosome-binding protein MDM38 

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Top 50 coexpressed genes to LETM1 (fca-r.1 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 fca5012   Parkinson disease  5 241 3.45
 fca5016   Huntington disease  5 277 3.18
 fca5020   Prion disease  4 245 2.47
 fca5014   Amyotrophic lateral sclerosis  4 374 -
 fca5022   Pathways of neurodegeneration - multiple diseases  4 480 -

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fca:LETM1 (leucine zipper and EF-hand containing transmembrane protein 1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

fca-r.1
for
LETM1
cfa-u.3
for
LETM1
hsa-u.4
for
LETM1
mmu-u.4
for
Letm1
rno-u.3
for
Letm1
mcc-u.3
for
LETM1
gga-u.3
for
LETM1
dre-u.3
for
letm1
dme-u.3
for
Letm1
cel-u.3
for
letm-1
sce-u.3
for
YLH47
sce-u.3
for
MDM38
1 NPLOC4 NPL4 homolog, ubiquitin recognition factor 101097934 6.2 3.6
 3.3
 3.5
 3.4
 4.5
 -0.4
 -0.5
 2.7
 2.1
1.0
 1.5
 0.6
2 AP2A1 adaptor related protein complex 2 subunit alpha 1 101101430 5.8 3.0
1.1
 1.7
1.3
 2.5
2.0
 2.1
1.4
 2.4
2.0
 0.5
 0.3
 0.8
 0.9
 -0.7
 1.2
3 AP1M1 adaptor related protein complex 1 subunit mu 1 101093585 5.6 2.8
-0.2
 2.7
1.1
 1.6
1.4
 1.8
1.1
 2.2
1.2
 2.4
-0.5
 0.7
0.3
 0.2
-0.8
 0.3
-0.0
 -0.1
-0.7
 1.0
-0.2
4 HGS hepatocyte growth factor-regulated tyrosine kinase substrate 101088702 5.6 2.6
 2.0
 1.6
 1.1
 1.9
 0.6
 4.5
 0.9
 6.5
 1.3
 2.0
5 GPS1 G protein pathway suppressor 1 101081015 5.5 3.4
 2.9
 3.2
 1.1
 3.3
 0.3
 -1.4
 0.4
0.4
 1.2

6 VARS1 valyl-tRNA synthetase 1 101090770 5.5 4.0
1.5
 5.6
4.2
 2.8
0.7
 1.3
1.0
 5.1
4.7
 0.1
-0.5
 0.6
-0.3
 3.7
0.4
 3.5
2.9
 0.4
 1.9
7 GTF2F1 general transcription factor IIF subunit 1 101095797 5.3 2.9
 2.4
 2.8
 1.9
 4.3
1.2
 2.2
 3.6

8 EIF5A eukaryotic translation initiation factor 5A 101095386 5.2 2.7
1.3
 1.9
0.3
 0.1
-0.8
 1.3
-0.1
 1.3
0.8
 1.7
0.8
 1.0
-0.7
 -0.6
 -0.4
-1.7
 0.2
-0.3
 1.2
-0.5
9 HK1 hexokinase 1 101098403 5.2 1.6
1.6
 2.3
1.9
 0.6
0.1
 1.4
1.2
 3.3
1.8
 1.2
0.7
 1.1
0.1
 1.9
0.5
 2.1
1.8
 1.7
0.8
 -0.8
-1.0
10 NUDCD3 NudC domain containing 3 111559463 5.0 2.7
 1.7
 3.4
 4.5
 1.7
 1.8
 0.8
 -2.1


11 KEAP1 kelch like ECH associated protein 1 101091260 5.0 2.2
 2.0
 2.5
 1.8
 3.1
0.1
 3.6


12 DAP3 death associated protein 3 101087963 4.9 1.4
 0.6
 0.9
 1.8
 0.8
 1.3
 0.4
 -1.4
 1.4

13 INO80E INO80 complex subunit E 101100019 4.9 2.0
 -0.2
 1.0
 -1.4
 0.6
 -0.2
 -0.3
 -2.7


14 ZDHHC7 zinc finger DHHC-type palmitoyltransferase 7 101083311 4.9 3.5
2.8
 1.7
0.4
 3.9
2.4
 2.3
1.9
 2.9
1.2
 -0.2
-0.5
 2.3
2.0
 -1.4
 0.3

15 MED9 mediator complex subunit 9 101080840 4.8 1.6
 1.8
 0.1
 1.0
 1.5
 -0.4
 -0.6



16 BAP1 BRCA1 associated protein 1 101092671 4.8 2.8
 4.6
 1.9
 1.3
 2.8
 0.2
 1.6
 0.7


17 RABL6 RAB, member RAS oncogene family like 6 101095866 4.8 2.6
 3.1
 2.2
 -0.2
 3.2
 2.2
 2.2
0.8
2.0

18 USP5 ubiquitin specific peptidase 5 101085296 4.8 4.1
1.5
 3.7
0.6
 2.7
0.5
 1.3
 5.2
-0.3
 0.6
0.5
 -0.1
-0.2
 0.0
-0.8
 1.6
19 CSNK1G2 casein kinase 1 gamma 2 101100186 4.8 2.0
-0.3
 2.2
1.2
 1.1
0.7
 1.6
0.3
 1.5
0.1
 1.6
-0.5
 1.4
1.1
 2.3
 0.2
 1.0
-1.7
 2.0
1.9
20 UBN1 ubinuclein 1 101092226 4.8 1.4
-1.0
 2.4
-0.6
 -0.1
-1.9
 0.6
-0.6
 1.6
-1.1
 3.1
0.2
 0.1
0.1
 0.0


21 KATNB1 katanin regulatory subunit B1 101086522 4.8 1.9
 2.2
 2.2
 1.8
 2.2
 -1.4
 -0.3
 0.1


22 ACTR1A actin related protein 1A 101081833 4.8 3.0
2.2
 3.3
1.4
 3.1
2.6
 3.3
2.5
 3.5
2.3
 0.5
0.4
 0.6
0.3
 0.7
0.7
 3.0
0.5
 1.2
0.4
 1.5
-1.1
23 RAB1B RAB1B, member RAS oncogene family 101083111 4.7 1.0
1.0
 0.9
-0.6
 3.1
0.3
 1.9
1.7
 2.5
1.4
 0.7
 1.6
1.4
 0.1
 0.1
 0.7
 -0.5
24 SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha 101082292 4.7 1.3
0.9
 3.1
-1.1
 3.2
-0.7
 2.4
-1.1
 4.8
-0.2
 0.8
0.3
 0.8
-0.5
 1.5
 3.5

25 EXOC3 exocyst complex component 3 101096289 4.7 1.9
0.9
 0.9
-0.7
 4.7
-0.1
 3.7
-1.4
 1.7
0.0
 0.9
-1.5
 0.7
-0.1
 0.9
 1.8
 0.4
 1.4
26 ADRM1 ADRM1 26S proteasome ubiquitin receptor 101097227 4.7 4.6
 2.1
 2.9
 1.5
 2.4
 0.2
 -0.4
 2.6
-0.0
 0.8

27 PSMD2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 101095190 4.7 3.9
 3.3
 3.3
 4.1
 5.1
 2.5
 0.8
 2.9
 2.4
 1.7
 -0.5
28 TUBB4B tubulin beta 4B class IVb 101084324 4.7 4.1
2.6
 1.6
0.7
 1.9
0.4
 2.8
2.0
 3.3
2.2
 1.1
0.8
 0.5
-0.3
 0.6
0.1
 1.8
1.3
 0.6
 -0.3
29 TIGD5 tigger transposable element derived 5 101090236 4.6 2.7
1.0
 2.5
2.4
 2.1
1.6
 0.5
-0.2
 2.4
1.3
 -1.5
 -0.3
 0.9
0.3
 -1.3
 0.9
 1.1
30 KPNA6 karyopherin subunit alpha 6 101097823 4.6 2.0
1.6
 5.2
1.4
 2.8
1.1
 2.6
2.5
 2.0
1.5
 3.6
2.3
 1.6
1.5
 -0.2
 -0.0
 -0.7
 1.1
31 WDR1 WD repeat domain 1 101091531 4.6 4.5
 4.5
 1.4
 1.0
 3.1
 -0.6
 -1.7
 -1.8
 0.2
-0.4
 -1.1
 -0.3
32 BAG6 BAG cochaperone 6 101086144 4.5 2.1
 0.8
 2.0
 0.2
 2.2
 0.7
 1.8
0.8
 2.6


33 PEX10 peroxisomal biogenesis factor 10 101088860 4.5 0.4
 0.8
 2.1
 0.5
 1.9
 -0.4
 -0.5
 2.2
-1.0
 -0.7
34 PPP6R1 protein phosphatase 6 regulatory subunit 1 101085846 4.5 2.7
1.2
 4.2
3.6
 3.5
-0.4
 2.8
1.7
 4.6
1.0
 2.5
1.2
 1.4
1.3
 3.6
 3.9
 1.3
0.5
 0.9
0.7
35 DRAP1 DR1 associated protein 1 101101589 4.5 1.8
 0.3
 1.0
 0.1
 -0.8
 -0.5
 -0.5
-0.7
 0.9
 1.2
 -1.1
 0.1
36 LRWD1 leucine rich repeats and WD repeat domain containing 1 101091169 4.5 1.5
 3.3
 -0.5
 -2.4
 1.8
 -0.1
 1.1



37 DDA1 DET1 and DDB1 associated 1 101096792 4.4 1.1
 2.6
 1.8
 -0.1
 1.3
 -1.0
 0.1
 -1.4


38 RRP12 ribosomal RNA processing 12 homolog 101098492 4.4 2.3
 2.7
 2.8
 1.7
 1.8
 2.7
 1.2
 0.7
 0.9
 1.8
 2.1
39 PIGQ phosphatidylinositol glycan anchor biosynthesis class Q 101088291 4.4 1.6
 0.6
 4.5
 2.4
 3.1
 -0.5
 1.6
 -1.2
 -1.1
 -1.7
 0.1
40 UPF1 UPF1 RNA helicase and ATPase 101096043 4.4 2.6
 5.1
 2.2
 1.1
 3.6
 3.0
 2.8
 2.2
 2.0
 -0.2
 -0.4
41 ZNF574 zinc finger protein 574 101084668 4.3 1.8
 1.7
 1.8
 -0.9
 2.5


1.0

42 NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 101085326 4.3 3.2
 1.7
1.0
 1.1
 1.7
 -0.5
 1.0
 -1.4
 0.9
 0.6
43 PRKACA protein kinase cAMP-activated catalytic subunit alpha 101090494 4.3 0.5
0.3
 1.7
0.7
 2.2
1.1
 0.6
0.2
 1.9
1.2
 1.1
-0.3
 3.0
1.4
 4.3
1.9
 0.3
0.1
 0.8
-0.6
 2.3
-1.0
44 CSNK1D casein kinase 1 delta 101091915 4.3 3.4
2.2
 0.7
0.3
 0.7
-0.5
 2.7
1.5
 2.4
1.2
 1.7
1.6
 1.3
0.6
 1.2
-0.3
 0.4
-1.2
 2.6
 0.1
45 INTS1 integrator complex subunit 1 101089564 4.3 4.9
 3.8
 3.4
 4.9
 5.1
 1.1
 -0.6
 2.6
 1.5

46 NAPA NSF attachment protein alpha 101088535 4.2 1.6
-1.0
 0.8
-0.7
 0.4
-0.0
 0.9
0.6
 1.6
-0.9
 0.8
-0.3
 1.9
0.8
 1.6
 0.7
 -1.1
 -0.9
47 ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 101091476 4.2 3.8
1.5
 2.6
2.1
 2.8
0.6
 1.8
-0.2
 3.3
1.4
 1.4
-0.7
 1.5
1.2
 0.4
 -0.1

48 STRN4 striatin 4 101099851 4.2 2.3
0.6
 3.5
1.8
 1.8
0.3
 2.2
1.1
 2.3
0.1
 2.3
2.2
 1.6
0.6
 2.4
 1.8
 -0.6
 -1.4
49 MED27 mediator complex subunit 27 101088890 4.1 0.8
 0.3
 2.0
 -0.0
 2.6
 1.2
 -0.3
 -0.1


50 NACC1 nucleus accumbens associated 1 101088308 4.1










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