Orthologous genes in OrthoFinder**

Species Gene Description
 mcc-u.3   SYNE1   spectrin repeat containing nuclear envelope protein 1 
 mcc-r.3   SYNE1   spectrin repeat containing nuclear envelope protein 1 
 cfa-u.3   SYNE1   spectrin repeat containing nuclear envelope protein 1 
 dre-u.3   syne1a   spectrin repeat containing, nuclear envelope 1a 
 dre-u.3   syne2a   spectrin repeat containing, nuclear envelope 2a 
 dre-u.3   syne2b   spectrin repeat containing, nuclear envelope 2b 
 dme-u.3   Msp300   Muscle-specific protein 300 kDa 

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Top 50 coexpressed genes to SYNE1 (mcc-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mcc5235   PD-L1 expression and PD-1 checkpoint pathway in cancer  5 87 5.17
 mcc4658   Th1 and Th2 cell differentiation  5 87 5.17
 mcc4650   Natural killer cell mediated cytotoxicity  5 94 5.01
 mcc4660   T cell receptor signaling pathway  5 100 4.88
 mcc4659   Th17 cell differentiation  5 103 4.81

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mcc:SYNE1 (spectrin repeat containing nuclear envelope protein 1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

mcc-u.3
for
SYNE1
mcc-r.3
for
SYNE1
cfa-u.3
for
SYNE1
dre-u.3
for
syne1a
dre-u.3
for
syne2a
dre-u.3
for
syne2b
dme-u.3
for
Msp300
1 NLRC3 NLR family CARD domain containing 3 705633 8.1 4.3
 0.1
 0.7
 -0.0
 0.2
2 CYFIP2 cytoplasmic FMR1 interacting protein 2 714984 EGK_17071 7.7 4.0
 0.7
-0.6
 1.0
0.8
 0.0
-0.4
 0.3
-0.2
 -0.1
3 CEP250 centrosomal protein 250 705173 5.4 2.9
 2.1
 -0.2
 0.2
 0.3
 0.4
4 GRK5 G protein-coupled receptor kinase 5 100427251 5.2 2.8
 0.8
0.5
 3.8
1.7
 -0.7
-0.8
 2.8
1.0
 0.5
5 UBASH3A ubiquitin associated and SH3 domain containing A 722456 4.9 2.6
 -0.1
-1.1
 1.6
1.6
 -0.7
-1.3
 0.3
0.2
 -1.6
6 MADD MAP kinase activating death domain 713613 EGK_06296 4.6 2.4
 2.0
 3.6
 0.9
 3.0
 1.6
7 EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 711173 4.5 2.4
 2.1
-0.8
 0.9
0.0
 1.8
-0.7
 1.3
-0.9
 -0.2
8 LAX1 lymphocyte transmembrane adaptor 1 702011 4.5 2.4
 1.5



9 IRAG2 inositol 1,4,5-triphosphate receptor associated 2 707643 4.4 2.4
 1.0
 -0.8
 1.2
 0.4
10 SH2D1A SH2 domain containing 1A 574156 EGK_20903 4.3 2.3
 1.1
 -1.4
 -0.3
 -0.3
11 STK39 serine/threonine kinase 39 704855 4.3 2.3
 0.8
-0.2
 0.6
-0.4
 0.2
-0.6
 -0.4
-1.1
 0.8
12 ABLIM1 actin binding LIM protein 1 698641 4.2 2.3
 1.5
-1.0
 1.5
1.2
 -0.2
-0.3
 2.0
1.3
 2.6
13 TTC21B tetratricopeptide repeat domain 21B 707811 4.2 2.3
 2.4
-0.1
 1.4
 2.5
 -0.9
14 GLCCI1 glucocorticoid induced 1 696004 4.2 2.2
 1.6
 0.4
 -0.2
 -1.4
15 KIF21B kinesin family member 21B 710792 4.2 2.2
 1.2
0.3
 1.8
1.6
 0.4
0.3
 2.2
1.2
 -0.5
16 MAGEE1 MAGE family member E1 705379 4.2 2.2




17 CCDC69 coiled-coil domain containing 69 713304 4.1 2.2
 -0.4
 -0.8
 0.5
 0.9
18 TNIK TRAF2 and NCK interacting kinase 695414 EGK_11902 4.1 2.2
 1.6
0.2
 2.3
1.8
 2.9
1.2
 1.3
1.2
 0.7
19 MAPRE2 microtubule associated protein RP/EB family member 2 707996 EGK_09627 4.0 2.1
 1.1
-1.0
 1.2
1.1
 0.1
-0.2
 0.4
-0.6
 -0.0
-1.1
20 MACF1 microtubule actin crosslinking factor 1 718651 4.0 2.1
 6.2
2.6
 5.4
4.0
 2.1
0.6
 3.8
1.9
 6.9
21 LCK LCK proto-oncogene, Src family tyrosine kinase 717704 EGK_00506 4.0 2.1
 2.2
0.6
 2.9
1.0
 2.5
1.9
 0.9
0.7
 0.1
-0.9
22 REV1 REV1 DNA directed polymerase 709475 4.0 2.1
 1.6
 1.8
 -0.1
 0.6
 0.3
23 DTX3 deltex E3 ubiquitin ligase 3 715175 4.0 2.1
 -0.3
 -0.5
 0.1
 -0.7
24 ZNF142 zinc finger protein 142 702214 3.9 2.1
 1.7
 0.8
 -0.4
 -0.6
 0.0
25 ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 707768 3.9 2.1
 2.2
0.5
 2.8
2.4
 2.1
1.1
 1.2
0.6
 3.9
26 LOC697893 uncharacterized LOC697893 697893 3.9 2.1




27 KDM2A lysine demethylase 2A 712907 3.8 2.1
 0.9
-0.1
 3.8
1.2
 2.5
0.2
 0.9
0.8
 0.2
28 NCALD neurocalcin delta 706856 EGK_19177 3.8 2.0
 2.8
0.9
 1.7
1.2
 0.1
-0.2
 0.1
-0.2
 1.2
0.9
29 CLEC2D C-type lectin domain family 2 member D 717228 3.8 2.0
 1.0
1.0
 -0.3
-0.6
 -0.7
-1.2
 -0.6
-0.8
 0.0
30 LOC106999340 immunoglobulin kappa light chain 106999340 3.8 2.0
 0.5
 -1.1
 -0.4
 -1.0
31 MECP2 methyl-CpG binding protein 2 700174 3.8 2.0
 0.8
 1.1
 -0.4
 0.1
32 CABIN1 calcineurin binding protein 1 700566 3.8 2.0
 1.0
 1.2
 0.8
 1.9
33 USP47 ubiquitin specific peptidase 47 701660 3.8 2.0
 2.5
 2.0
 0.5
 1.0
 3.8
34 DIDO1 death inducer-obliterator 1 698313 3.8 2.0
 0.5
 -0.7
 1.2
 0.5
35 TOP2B DNA topoisomerase II beta 677709 3.8 2.0
 1.8
-0.5
 2.6
1.4
 1.6
1.1
 0.9
0.2
 0.6
36 NUP210 nucleoporin 210 693669 3.7 2.0
 -0.4
 0.6
 -2.3
 -0.7
 0.3
37 SYNE2 spectrin repeat containing nuclear envelope protein 2 706759 3.7 2.0
 0.6



38 SEPTIN1 septin 1 710226 3.7 2.0
 2.4
0.7
 2.4
2.0
 3.4
1.0
 1.5
1.1
 -1.3
-1.9
39 ALMS1 ALMS1 centrosome and basal body associated protein 706612 3.7 2.0
 1.8



40 PTPN7 protein tyrosine phosphatase non-receptor type 7 706254 3.7 2.0
 0.9
0.3
 -0.1
 -0.6
 -0.1
41 NEK9 NIMA related kinase 9 701707 3.7 2.0
 0.7
 0.6
 -0.2
 1.7
42 DPF3 double PHD fingers 3 714778 3.7 2.0
 0.6
-0.8
 1.6
1.3
 2.4
0.8
 2.4
0.3
 0.4
-0.6
43 TNRC6C trinucleotide repeat containing adaptor 6C 714829 3.7 2.0
 2.9
1.5
 2.7
2.5
 0.6
0.2
 1.7
1.5
 -0.1
44 PRKCQ protein kinase C theta 722559 3.7 2.0
 1.7
1.0
 1.6
1.2
 1.9
1.0
 0.8
0.7
 2.1
0.9
45 ZAP70 zeta chain of T cell receptor associated protein kinase 70 707555 3.7 2.0
 -0.6
-1.4
 -0.0
-1.5
 0.3
-0.5
 0.1
-0.4
 -0.1
46 UBTF upstream binding transcription factor 711597 EGK_08799 3.7 2.0
 -0.9
 0.1
 1.5
 0.4
47 NFATC2 nuclear factor of activated T cells 2 710601 3.6 1.9
 2.3
 -0.9
 -0.8
 -0.9
48 SNRNP200 small nuclear ribonucleoprotein U5 subunit 200 705184 3.6 1.9
 1.8
-0.1
 1.5
0.1
 1.1
0.1
 1.0
0.1
 1.1
-0.1
49 SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor 716230 EGK_08333 3.6 1.9
 1.2
 0.5
 1.6
 1.2
 1.0
50 LAT linker for activation of T cells 704656 3.6 1.9
 0.4



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