Orthologous genes in OrthoFinder**

Species Gene Description
 mcc-u.3   EIF6   eukaryotic translation initiation factor 6 
 mcc-r.3   EIF6   eukaryotic translation initiation factor 6 
 mcc-m.4   EIF6   eukaryotic translation initiation factor 6 
 hsa-u.4   EIF6   eukaryotic translation initiation factor 6 
 mmu-u.4   Eif6   eukaryotic translation initiation factor 6 
 rno-u.3   Eif6   eukaryotic translation initiation factor 6 
 cfa-u.3   EIF6   eukaryotic translation initiation factor 6 
 gga-u.3   EIF6   eukaryotic translation initiation factor 6 
 dre-u.3   eif6   eukaryotic translation initiation factor 6 
 dme-u.3   eIF6   eukaryotic translation initiation factor 6 
 cel-u.3   eif-6   Eukaryotic translation initiation factor 6 
 sce-u.3   TIF6   translation initiation factor 6 
 spo-u.3   sap114   splicing factor Sap114 

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Top 50 coexpressed genes to EIF6 (mcc-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mcc5022   Pathways of neurodegeneration - multiple diseases  6 426 2.73
 mcc4141   Protein processing in endoplasmic reticulum  5 161 3.88
 mcc5014   Amyotrophic lateral sclerosis  5 331 2.48
 mcc5010   Alzheimer disease  5 342 2.41
 mcc3040   Spliceosome  4 130 3.18

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mcc:EIF6 (eukaryotic translation initiation factor 6) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

mcc-u.3
for
EIF6
mcc-r.3
for
EIF6
mcc-m.4
for
EIF6
hsa-u.4
for
EIF6
mmu-u.4
for
Eif6
rno-u.3
for
Eif6
cfa-u.3
for
EIF6
gga-u.3
for
EIF6
dre-u.3
for
eif6
dme-u.3
for
eIF6
cel-u.3
for
eif-6
sce-u.3
for
TIF6
spo-u.3
for
sap114
1 CSNK2B casein kinase 2 beta 715807 EGK_14715 7.0 3.0
 4.3
 6.2
 4.3
 4.1
 3.6
 0.2
 0.8
 1.0
0.6
 5.0
 2.0
1.4
 2.1
2 EIF4A3 eukaryotic translation initiation factor 4A3 712141 6.8 3.6
2.7
-0.2
 6.7
3.6
 6.9
4.0
 5.7
4.4
 4.0
1.2
 3.3
2.5
 1.2
0.4
 4.5
4.0
 2.1
1.5
3 HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 700018 EGK_20527 6.7 3.5
5.5
 0.5
 2.2
 1.5
 2.9
 1.9
 -0.0
 0.8

4 BCAP31 B cell receptor associated protein 31 696663 6.6 2.7
 4.3
 5.3
0.7
 1.0
-0.6
 2.7
-2.3
 2.5
1.6
 2.3
-0.1
 2.3
0.8
 2.0
 3.1

5 PSMD8 proteasome 26S subunit, non-ATPase 8 721897 6.1 3.3
 3.0
 6.4
 5.0
 4.1
 2.8
 1.6
 2.2
 0.5
-0.4
 1.0
 -0.0
6 PHB prohibitin 699334 6.0 3.2
 3.0
 6.8
 3.3
 3.7
 3.1
 2.3
 3.5
 4.5
 4.7
 0.0
 0.1
7 NSFL1C NSFL1 cofactor 715743 6.0 3.1
 3.2
 5.2
-1.4
 4.2
-2.3
 5.8
-2.5
 7.4
-0.3
 2.1
-1.3
 1.8
 3.3
0.2
-0.6
 -1.5
8 COPE COPI coat complex subunit epsilon 719631 6.0 3.2
4.4
 4.3
 4.6
 2.7
 2.7
 4.6
 1.4
 1.4

9 SNRPB small nuclear ribonucleoprotein polypeptides B and B1 716578 6.0 3.3
 2.9
 7.2
 8.3
 5.0
 8.0
1.6
 2.1
 3.2
 4.0
 5.6
 1.4
10 DIABLO diablo IAP-binding mitochondrial protein 701896 EGK_04301 5.9 2.3
 4.0
 2.7
 0.9
 3.5
 0.7
 1.5
 1.4
0.7



11 RER1 retention in endoplasmic reticulum sorting receptor 1 694540 EGK_00133 5.9 3.0
 3.0
 2.2
 2.3
 3.4
 1.1
 1.8
 1.5
 0.8
 1.6
 -0.1
 -0.0
12 PSMC3 proteasome 26S subunit, ATPase 3 713356 5.8 3.1
 2.9
 6.2
 4.6
 5.1
 3.1
 2.7
 3.4
 1.3
 2.8
 0.3
13 THOC5 THO complex 5 714842 5.8 2.7
 3.4
 2.7
 2.8
 2.0
 2.7
 1.9
 2.0
 0.4
 -0.4

14 TRAPPC4 trafficking protein particle complex subunit 4 702469 5.8 2.7
 3.3
 4.3
 4.5
 1.4
 2.4
 1.0
 -0.2
 0.2
 0.3
 -1.5
 0.5
15 ERGIC3 ERGIC and golgi 3 704736 5.7 3.0
 2.9
 5.6
 2.9
 3.3
 3.8
 2.8
 1.3
 0.2
 -0.8
 -0.0
 -1.2
16 EDF1 endothelial differentiation related factor 1 708611 5.7 1.9
 4.3
 4.1
 3.9
 2.5
 2.0
 0.9
 3.0
 5.8
 4.5
 1.8
 0.1
17 ENO1 enolase 1 709378 5.7 2.9
 2.9
 5.7
0.1
 4.0
2.5
 3.5
0.5
 2.4
0.5
 1.0
-0.9
 0.9
0.8
 0.0
 -0.8
 0.2
-0.1
18 DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory 698709 5.6 3.4
 2.3
2.3
 2.9
3.0
 2.3



19 RAB8A RAB8A, member RAS oncogene family 100423251 EGK_10269 5.6 3.0
2.2
1.0
 2.9
1.3
 4.8
0.7
 0.6
0.1
 2.5
2.2
 0.9
0.3
 -1.3
-1.6
 3.2
1.2
 2.9
20 CIAO1 cytosolic iron-sulfur assembly component 1 705318 EGK_05570 5.6 2.7
 3.1
 2.3
 2.3
 2.5
 2.8
 1.1
 1.0
 1.4
 3.6

21 SSR2 signal sequence receptor subunit 2 719383 EGK_01404 5.6 3.4
 2.3
 1.4
 3.1
 4.7
 2.3
 1.2
 2.3
 2.0
 2.1

22 PPP1CA protein phosphatase 1 catalytic subunit alpha 721735 5.6 2.8
 2.9
 5.2
-0.3
 3.2
-1.4
 4.4
-0.3
 2.5
0.0
 2.8
1.2
 1.4
0.6
 0.2
-0.3
 2.2
2.1
 3.4
0.1
23 MFSD5 major facilitator superfamily domain containing 5 702021 EGK_03704 5.5 2.5
 3.3
 3.0
 4.4
 4.4
 4.7
 0.9
 -1.6
0.8

24 GSTP1 glutathione S-transferase pi 1 721704 5.5 1.6
 4.4
 4.3
 1.5
0.1
 3.1
-0.9
 2.4
0.9
 0.2
 1.2
0.9
0.8

25 PPIE peptidylprolyl isomerase E 716340 5.5 3.4
 2.1
 2.0
 3.9
 4.2
 0.7
 1.9
 2.7
 1.2
 1.6

26 PUF60 poly(U) binding splicing factor 60 699008 5.4 3.1
 2.4
 5.6
 4.4
 4.6
 6.2
 2.3
 0.4
0.3
 0.3
 3.3

27 CCT3 chaperonin containing TCP1 subunit 3 718374 EGK_01417 5.4 2.9
5.8
 4.2
 4.9
 4.1
 1.1
 2.8
 4.1
 1.0
 2.3
 0.9
28 NOB1 NIN1 (RPN12) binding protein 1 homolog 705344 EGK_12945 5.3 2.8
1.9
 3.4
 3.0
 4.4
 0.4
 1.7
 5.5
 2.4
 1.2
29 RPS5 ribosomal protein S5 711259 EGK_11175 5.2 2.5
 3.0
 5.0
 3.3
 4.5
 3.1
 1.7
 3.3
 2.3
1.5
 5.1
 0.6
30 PPIB peptidylprolyl isomerase B 706757 5.2 2.8
 2.6
 1.7
-0.9
 0.2
-0.3
 2.7
-0.7
 2.0
-0.1
 0.6
0.2
 2.2
-0.2
 0.9
 1.9
-0.8
 0.0
31 SEC13 SEC13 homolog, nuclear pore and COPII coat complex component 697339 EGK_11422 5.2 2.9
 2.5
 2.3
 3.9
 4.0
 2.1
 3.9
 1.4
 2.9
 1.4
 2.1
 0.3
32 SNX17 sorting nexin 17 701614 EGK_05165 5.2 3.3
 1.8
 3.9
 3.8
 3.3
 2.1
 2.0
 -0.8
 -0.8
 -1.9

33 RPL8 ribosomal protein L8 708535 EGK_19389 5.1 2.2
 3.2
 3.3
 4.1
3.6
 1.8
 3.2
 2.3
 2.8
 0.8
0.1
 -1.1
34 ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit 574267 5.1 2.9
 2.3
 3.4
 4.0
 4.3
 1.7
0.8
 1.4
 -0.8
 -2.2
35 TMEM147 transmembrane protein 147 709568 EGK_10483 5.1 2.9
 2.3
 3.5
 1.5
 2.3
 2.2
 1.1
 2.3
 0.1
 1.9

36 PSMB3 proteasome 20S subunit beta 3 694318 5.0 2.7
7.9
 4.9
 5.3
 4.0
 0.8
 4.3
 1.0
 1.5
 1.1
 -0.4
37 EIF4A1 eukaryotic translation initiation factor 4A1 106993879 5.0 2.7
2.7
-0.2
 6.7
3.6
 6.9
4.0
 5.7
4.4
 4.0
1.2
 3.3
2.5
 1.2
0.4
 4.5
4.0
 2.1
1.5
38 ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 710296 EGK_03772 5.0 2.4
 2.9
 4.2
0.1
 -0.1
-0.1
 0.7
0.6
 1.0
0.9
 1.5
0.5
 1.1
-0.1
 -0.5
1.9
1.3
39 SSR4 signal sequence receptor subunit 4 697266 5.0 2.4
 2.8
 2.4
 2.0
 1.4
 1.1
2.4
 2.9
 1.5

40 RUVBL2 RuvB like AAA ATPase 2 100428794 5.0 2.6
6.4
 3.8
 4.4
 4.5
2.1
 3.3
 4.9
 2.3
41 EXOSC4 exosome component 4 700012 4.9 3.0
 1.9
 4.1
 5.7
 4.8
 5.6
 0.4
 1.3
 7.0
 3.4
 3.5
42 MRPS18A mitochondrial ribosomal protein S18A 701465 4.9 2.9
 2.1
 3.9
 1.9
 4.0
 1.5
 -0.5
 1.3
 0.7
 1.2

43 TBCB tubulin folding cofactor B 712355 4.9 2.6
4.1
 4.3
 5.2
 2.1
 1.4
 3.3
 -0.7
 -0.2
 -0.3
-0.7
44 GET3 guided entry of tail-anchored proteins factor 3, ATPase 717734 4.9 2.5
 2.6
 3.3
 2.0
 3.3
 1.9
 0.8
 1.0
 3.4
 -0.7
 -0.3
45 EIF3I eukaryotic translation initiation factor 3 subunit I 708145 4.9 3.2
 1.7
 4.6
 2.8
 4.8
 2.0
 3.7
 4.2
 1.5
 5.8
 0.9
0.8
 2.5
46 SDHAF2 succinate dehydrogenase complex assembly factor 2 693401 EGK_06141 4.9 2.2
 2.9
 3.4
 -1.6
 -0.5
 3.5
 -0.2
 2.1
 -0.2
-0.6
 1.6
 -0.9
 -0.1
47 RNF181 ring finger protein 181 695977 EGK_05521 4.8 2.6
 2.3
 5.1
 -0.3
 2.3
 1.7
1.3
-0.4

48 SARS1 seryl-tRNA synthetase 1 695046 4.8 2.6
 2.4
 2.2
 3.7
 3.9
 4.6
 0.9
 2.1
 7.3
 4.0
 -0.6
 0.1
49 COPZ1 COPI coat complex subunit zeta 1 705176 EGK_03733 4.8 2.2
 2.9
 2.1
0.4
 2.6
-2.0
 2.3
-0.2
 -0.9
 2.2
 3.8
-0.4
 1.1
 0.1
 0.8
50 TMED9 transmembrane p24 trafficking protein 9 701114 4.8 2.5
2.5
-0.4
 1.8
1.2
 3.4
0.5
 3.5
0.6
 2.1
-0.1
 1.3
0.0
 0.3
 -0.0
-0.3
 1.3
-0.6
 0.3
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