Orthologous genes in OrthoFinder**

Species Gene Description
 mcc-u.3   IL1B   interleukin 1 beta 
 mcc-r.3   IL1B   interleukin 1 beta 
 mcc-m.4   IL1B   interleukin 1 beta 
 hsa-u.4   IL1B   interleukin 1 beta 
 mmu-u.4   Il1b   interleukin 1 beta 
 rno-u.3   Il1b   interleukin 1 beta 
 cfa-u.3   IL1B   interleukin 1 beta 
 gga-u.3   IL1B   interleukin 1, beta 

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Top 50 coexpressed genes to IL1B (mcc-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mcc4060   Cytokine-cytokine receptor interaction  13 196 6.88
 mcc4062   Chemokine signaling pathway  10 169 6.11
 mcc4061   Viral protein interaction with cytokine and cytokine receptor  9 77 6.91
 mcc4620   Toll-like receptor signaling pathway  9 84 6.69
 mcc5163   Human cytomegalovirus infection  9 205 6.73

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mcc:IL1B (interleukin 1 beta) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

mcc-u.3
for
IL1B
mcc-r.3
for
IL1B
mcc-m.4
for
IL1B
hsa-u.4
for
IL1B
mmu-u.4
for
Il1b
rno-u.3
for
Il1b
cfa-u.3
for
IL1B
gga-u.3
for
IL1B
1 LOC702712 hydroxycarboxylic acid receptor 2 702712 10.4 5.9
 4.5
 7.4
6.5
 8.3
-1.3
 4.2
 6.2
2 PTGS2 prostaglandin-endoperoxide synthase 2 716671 EGK_01845 8.1 4.2
8.9
 5.8
 2.5
 5.3
 3.0
3 CXCL8 C-X-C motif chemokine ligand 8 613028 7.9 3.3
 5.0
 10.9
8.0
 11.6
7.0
 8.3
6.0
 7.5
4.4
 8.5
7.3
4 OSM oncostatin M 717994 7.4 3.0
 4.8
 6.3
 7.6
4.5
5 CCL3 chemokine (C-C motif) ligand 3 619514 7.3 2.8
 5.1
 7.6
7.0
 8.1
7.9
 10.2
7.6
 6.2
5.9
 8.7
5.8
6 PLEK pleckstrin 698949 EGK_05393 7.1 3.4
 4.0
 3.8
 5.5
 6.0
 3.9
 2.4
7 BCL2A1 BCL2 related protein A1 712571 EGK_17743 7.0 3.2
 4.1
 5.8
 8.7
6.8
 7.9
 1.7
 2.1
8 PTX3 pentraxin 3 704985 6.7 4.1
 2.6
 3.2
 0.9
 0.3
 0.6
 0.6
9 CCR1 C-C motif chemokine receptor 1 574188 EGK_11714 6.6 3.6
 3.2
 2.8
0.3
 5.4
3.1
 3.8
2.6
 1.4
0.9
 0.3
-0.0
10 TLR4 toll like receptor 4 574360 EGK_07381 6.5 3.2
 3.6
 1.9
 0.1
 1.8
 2.1
 2.4
11 CCL4L1 chemokine (C-C motif) ligand 4-like 1 574217 6.4 3.2
 3.4
 7.6
7.0
 8.1
7.9
 10.2
7.6
 6.2
5.9
 8.7
5.8
12 ACOD1 aconitate decarboxylase 1 695991 6.4 3.4
 3.2
 4.6
 11.9
 3.7
 1.7
 5.4
13 C3AR1 complement C3a receptor 1 716086 6.2 3.3
2.5
 2.1
 3.0
 -1.0
 1.8
14 NFKBIZ NFKB inhibitor zeta 702846 6.1 3.2
 3.1
 5.9
2.9
 4.9
4.5
 4.7
2.9
 4.8
3.6
 4.6
2.0
15 G0S2 G0/G1 switch 2 717581 EGK_01699 5.9 3.7
 2.2
 6.0
 1.3
 1.1
 3.1
 1.4
16 LOC100426537 C-C motif chemokine 3-like 100426537 5.9 3.1
7.6
7.0
 8.1
7.9
 10.2
7.6
 6.2
5.9
 8.7
5.8
17 C1H1orf162 chromosome 1 C1orf162 homolog 705865 5.7 2.3
 3.8
 0.4
 3.6
1.1
18 LOC114673087 C-C motif chemokine 3-like 1 114673087 5.6 3.0
7.6
7.0
 8.1
7.9
 10.2
7.6
 6.2
5.9
 8.7
5.8
19 LOC100430627 C-C motif chemokine 4 100430627 5.6 3.0
7.6
7.0
 8.1
7.9
 10.2
7.6
 6.2
5.9
 8.7
5.8
20 HCK HCK proto-oncogene, Src family tyrosine kinase 715723 5.6 3.0
3.5
2.2
 6.4
4.2
 5.1
5.0
 2.5
1.8
 2.6
2.3
21 IL1A interleukin 1 alpha 700193 5.6 3.2
 2.4
 18.0
 11.4
 8.4
 6.8
22 IL1RN interleukin 1 receptor antagonist 701658 5.4 2.8
 2.8
 8.7
 6.3
 4.4
 5.3
23 CLEC4A C-type lectin domain family 4 member A 716122 EGK_03325 5.4 2.8
 2.8
 3.2
1.9
 11.6
8.8
 6.3
4.8
 5.9
4.8
 2.7
0.9
24 TLR2 toll like receptor 2 574290 5.3 2.2
 3.5
 3.5
1.2
 5.0
2.3
 6.7
5.4
 1.9
 6.5
2.1
25 CD274 CD274 molecule 716043 EGK_07725 5.3 2.8
 2.7
 2.6
 3.5
 2.6
 2.5
 1.9
1.2
26 IDO1 indoleamine 2,3-dioxygenase 1 574370 5.3 2.6
 2.8
 2.1
 -0.1
0.3
0.2
 -0.1
27 SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 694064 EGK_13379 5.2 2.5
 3.0
 1.8
 4.0
 6.5
 2.5
 1.0
28 PDE4B phosphodiesterase 4B 699309 EGK_00854 5.2 2.4
 3.0
 3.2
-0.7
 -0.1
-0.5
 2.8
0.8
 2.1
1.4
 2.7
0.7
29 FGR FGR proto-oncogene, Src family tyrosine kinase 716296 EGK_00444 5.1 2.2
 3.2
 3.5
2.2
 6.4
4.2
 5.1
5.0
 2.5
1.8
 2.6
2.3
30 LOC100424064 growth-regulated alpha protein-like 100424064 4.9 2.6
10.9
8.0
 11.6
7.0
 8.3
6.0
 7.5
4.4
 8.5
7.3
31 IER3 immediate early response 3 701939 EGK_14683 4.9 2.6
5.0
 3.4
 3.9
 3.0
32 MARCKS myristoylated alanine rich protein kinase C substrate 694077 4.9 2.6
1.7
 1.9
 1.3
 1.3
 0.2
33 LOC114680279 uncharacterized LOC114680279 114680279 4.8 2.5





34 GPR65 G protein-coupled receptor 65 693449 EGK_18440 4.8 2.5
 2.5
 1.6
 3.5
1.0
35 LOC114672235 uncharacterized LOC114672235 114672235 4.8 2.5





36 GPR84 G protein-coupled receptor 84 705309 EGK_03734 4.8 2.6
 2.3
 5.9
 5.4
 2.3
 2.7
37 SOCS3 suppressor of cytokine signaling 3 715680 4.8 2.5
 2.4
 5.1
 4.8
 4.4
 3.8
 5.4
38 FCAR Fc fragment of IgA receptor 664734 4.8 2.5
 2.5

2.5

39 FPR2 formyl peptide receptor 2 100426968 EGK_10975 4.7 2.5
5.0
1.0
 9.6
3.7
40 FFAR2 free fatty acid receptor 2 709026 EGK_10478 4.7 2.6
 2.2
 5.8
 0.8
7.5
41 EAF1 ELL associated factor 1 694057 EGK_12119 4.6 2.5
0.8
-0.3
 -0.1
 -0.0
 0.3
-0.8
 1.0
0.8
42 TREM1 triggering receptor expressed on myeloid cells 1 693558 4.6 1.8
 3.2
 6.7
3.1
 5.8
43 FCGR1A Fc fragment of IgG receptor Ia 714664 4.6 2.4
3.9
2.2
 5.7
3.8
 5.8
4.7
 4.2
0.5
 1.9
0.7
44 TNF tumor necrosis factor 715467 EGK_14705 4.6 3.2
 1.3
 6.2
 6.6
 6.7
 3.3
 2.2
45 SIGLEC11 sialic acid binding Ig like lectin 11 719127 4.5 1.6
 3.3
 3.1
2.8
 5.2
4.0
 2.8
1.8
 3.8
1.3
46 IRF1 interferon regulatory factor 1 707788 EGK_16834 4.5 2.3
 2.3
 2.5
 1.8
 3.1
 3.0
 1.9
47 CSF2RB colony stimulating factor 2 receptor subunit beta 697508 4.5 2.3
 2.4
 3.1
 4.9
3.7
 3.4
 1.6
 2.4
1.3
48 NLRP3 NLR family pyrin domain containing 3 701278 4.4 2.7
 1.9
 6.0
1.5
 10.5
3.5
 6.0
1.8
 2.8
0.9
 0.7
49 ATF3 activating transcription factor 3 710832 EGK_01674 4.4 2.5
 2.1
 1.9
 3.0
 2.6
 2.6
 2.2
50 LOC114677753 basic proline-rich protein-like 114677753 4.4 2.3





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