Orthologous genes in OrthoFinder**

Species Gene Description
 mcc-u.3   STAT4   signal transducer and activator of transcription 4 
 mcc-r.3   STAT4   signal transducer and activator of transcription 4 
 hsa-u.4   STAT4   signal transducer and activator of transcription 4 
 mmu-u.4   Stat4   signal transducer and activator of transcription 4 
 rno-u.3   Stat4   signal transducer and activator of transcription 4 
 cfa-u.3   STAT4   signal transducer and activator of transcription 4 
 gga-u.3   STAT4   signal transducer and activator of transcription 4 
 dre-u.3   stat4   signal transducer and activator of transcription 4 

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Top 50 coexpressed genes to STAT4 (mcc-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mcc4658   Th1 and Th2 cell differentiation  11 86 6.62
 mcc4660   T cell receptor signaling pathway  10 100 6.23
 mcc4659   Th17 cell differentiation  9 103 6.16
 mcc4650   Natural killer cell mediated cytotoxicity  8 94 6.39
 mcc5235   PD-L1 expression and PD-1 checkpoint pathway in cancer  7 87 6.59

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mcc:STAT4 (signal transducer and activator of transcription 4) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

mcc-u.3
for
STAT4
mcc-r.3
for
STAT4
hsa-u.4
for
STAT4
mmu-u.4
for
Stat4
rno-u.3
for
Stat4
cfa-u.3
for
STAT4
gga-u.3
for
STAT4
dre-u.3
for
stat4
1 SH2D2A SH2 domain containing 2A 718686 7.5 3.9
 3.9
 3.8
 3.0
 1.0
 2.8
 1.1
2 GPR171 G protein-coupled receptor 171 709960 7.2 3.8
 5.3
 6.3
 3.3
 2.5
 4.5
3 CCND2 cyclin D2 710379 EGK_03250 6.7 3.5
 1.9
-0.5
 1.5
-0.8
 1.4
0.5
 0.6
-0.6
 1.1
-0.2
 0.4
-0.5
4 ZAP70 zeta chain of T cell receptor associated protein kinase 70 707555 6.5 3.4
 3.5
-0.9
 2.9
2.5
 3.3
2.4
 1.5
-0.1
 5.2
1.3
 2.2
0.9
5 IL12RB2 interleukin 12 receptor subunit beta 2 700677 6.3 3.3
 3.6
 2.3
 1.6
 3.1
 0.8
 1.9
6 PRF1 perforin 1 710241 6.2 3.3
 4.3
 2.9
 5.0
 1.0
 2.6
 0.6
7 MCOLN2 mucolipin TRP cation channel 2 710909 6.2 3.3
 3.1
1.1
 1.6
1.2
 3.1
0.8
 2.0
1.5
 1.7
-0.9
 0.2
0.0
8 PRKCQ protein kinase C theta 722559 6.1 3.2
 4.9
4.3
 3.3
3.1
 2.4
2.2
 3.0
1.1
 1.5
1.3
 2.5
2.2
9 SYTL3 synaptotagmin like 3 699497 5.9 3.1
 4.2

2.8
 2.9
 0.7
10 CD247 CD247 molecule 697814 5.8 3.1
 5.0
 3.9
 3.7
 2.5
 3.0
11 JAKMIP1 janus kinase and microtubule interacting protein 1 722750 5.7 3.0
 3.2
2.0
 3.0
0.8
 1.7
-0.1
 0.0
-0.5
 0.1
-0.9
 0.5
-1.1
12 SCML4 Scm polycomb group protein like 4 698735 5.4 2.9

0.6
-0.5
 -1.4
13 GZMB granzyme B 716518 5.4 2.8
 4.7
3.4
 3.9
1.5
 3.8
3.7
 2.2
1.3
 1.7
14 MATK megakaryocyte-associated tyrosine kinase 100430078 5.3 2.8
 2.9
 0.7
 0.6
 1.3
 1.9
 0.2
15 LPXN leupaxin 702033 5.3 2.8
 3.5
-0.4
 2.4
0.5
 1.9
0.7
 -0.3
-0.4
 1.0
0.0
 1.2
1.0
16 SLA2 Src like adaptor 2 702574 EGK_02443 5.3 2.8
 4.6
 5.3
2.0
 2.4
 0.8
17 GFI1 growth factor independent 1 transcriptional repressor 706481 5.2 2.8
 3.8
 3.5
2.9
 3.1
 1.4
18 CD96 CD96 molecule 706836 5.2 2.8
 5.4
 6.7
 5.0
 0.3

19 LCK LCK proto-oncogene, Src family tyrosine kinase 717704 EGK_00506 5.2 2.8
 3.4
2.3
 5.9
2.1
 4.1
2.5
 3.1
3.0
 3.2
1.7
 4.5
2.6
20 ITK IL2 inducible T cell kinase 715471 EGK_17070 5.1 2.7
 6.3
 4.8
 3.5
 1.0
 5.1
 1.8
21 KLRD1 killer cell lectin like receptor D1 574145 5.1 2.7
 5.6
4.5
 4.5
 4.2
 2.3
1.9
 1.3
22 FASLG Fas ligand 574159 5.0 2.6
 4.2
 5.5
0.7

23 PRKCH protein kinase C eta 704356 4.8 2.6
 4.9
4.3
 3.3
3.1
 2.4
2.2
 3.0
1.1
 1.5
1.3
 2.5
2.2
24 LOC705095 T cell receptor gamma constant 2 705095 4.8 2.5
 5.2

1.6
 5.9
3.7
25 CD8A CD8a molecule 698329 4.8 2.5
 5.9
 4.1
 4.7
 1.7
 3.7
 0.5
26 NKG7 natural killer cell granule protein 7 719624 EGK_10964 4.8 2.5
 3.9
 5.1
 5.3
 1.7

27 TRAT1 T cell receptor associated transmembrane adaptor 1 705946 4.7 2.5
 5.2
 2.7
1.8
 4.3
28 CHST12 carbohydrate sulfotransferase 12 713591 4.7 2.5
 0.3
 0.1
 -0.7
 -0.4
 -1.1
 0.0
29 CD3E CD3e molecule 699467 EGK_06950 4.7 2.5
 4.0
 4.5
 2.9
 2.5
 3.9
30 UBASH3A ubiquitin associated and SH3 domain containing A 722456 4.7 2.5
 3.8
0.3
 4.5
0.7
 0.1
 2.1
1.1
 5.7
-1.1
 1.2
0.4
31 PTPN4 protein tyrosine phosphatase non-receptor type 4 695516 4.6 2.5
 2.4
 1.2
 1.4
 2.3
 -0.6
 0.9
0.6
32 LOC114673726 uncharacterized LOC114673726 114673726 4.6 2.5





33 SKAP1 src kinase associated phosphoprotein 1 697043 EGK_08473 4.6 2.4
 4.3
 4.9
 3.2
 2.1
 3.0
 2.6
34 GNLY granulysin 696059 4.6 2.4
 3.9

1.9
1.2

35 IL2RB interleukin 2 receptor subunit beta 696331 4.5 2.4
 3.6
 4.6
 4.9
 1.6
 4.6
 3.0
2.2
36 TIGIT T cell immunoreceptor with Ig and ITIM domains 710941 4.5 2.4
 4.1
 2.0
-0.0

37 GZMM granzyme M 715031 4.5 2.4
 2.1
3.3
2.9
38 OTULINL OTU deubiquitinase with linear linkage specificity like 698744 4.5 2.4
 1.7
 1.0
 0.0
 0.9
 0.4
39 TXK TXK tyrosine kinase 705104 4.5 2.4
 4.4
 4.2
 4.1
 1.2
 3.3
40 LOC100426632 C-C motif chemokine 4 100426632 4.4 2.3
 3.9
2.8
 3.9
1.2
 4.1
2.0
 0.7
0.4
 1.3
1.1
 1.6
1.5
41 CD40LG CD40 ligand 574160 4.4 2.3
 4.1
 1.9
1.9
 4.5
42 RUNX3 RUNX family transcription factor 3 719447 4.3 2.3
 3.0
0.3
 4.2
-0.5
 1.5
 2.0
1.7
 2.5
1.8
 1.8
1.1
43 CLEC2D C-type lectin domain family 2 member D 717228 4.3 2.3
 3.6
3.3
 4.6
4.6
 3.4
1.3
 3.5
1.2
 2.8
0.4
 0.7
0.2
44 CRTAM cytotoxic and regulatory T cell molecule 707560 4.3 2.3
 4.0
 2.5
 2.0
4.6
 1.1
45 CD3D CD3d molecule 699582 4.3 2.3
 3.2
 4.7
 3.8
 1.7
 5.4
46 PPP2R2B protein phosphatase 2 regulatory subunit Bbeta 706988 4.3 2.3
 2.2
0.6
 1.4
0.7
 0.2
-0.1
 -0.6
-0.8
 -0.0
-0.3
 0.5
-0.1
47 RHOF ras homolog family member F, filopodia associated 703262 4.2 2.2
 2.5
 3.1
 1.4
 0.5
 1.7
 1.3
48 IL12RB1 interleukin 12 receptor subunit beta 1 574199 4.2 2.2
 2.6
 2.1
1.4
 2.4
49 LOC703029 immunoglobulin lambda-1 light chain-like 703029 4.2 2.2




1.7
50 HCST hematopoietic cell signal transducer 574152 4.2 2.2
 2.2
 3.5
 2.8


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