Orthologous genes in OrthoFinder**

Species Gene Description
 mcc-u.3   RYR1   ryanodine receptor 1 
 mcc-r.3   RYR1   ryanodine receptor 1 
 mcc-u.3   RYR3   ryanodine receptor 3 
 mcc-u.3   RYR2   ryanodine receptor 2 
 hsa-u.4   RYR3   ryanodine receptor 3 
 hsa-u.4   RYR2   ryanodine receptor 2 
 hsa-u.4   RYR1   ryanodine receptor 1 
 mmu-u.4   Ryr3   ryanodine receptor 3 
 mmu-u.4   Ryr2   ryanodine receptor 2, cardiac 
 mmu-u.4   Ryr1   ryanodine receptor 1, skeletal muscle 
 rno-u.3   Ryr2   ryanodine receptor 2 
 rno-u.3   Ryr3   ryanodine receptor 3 
 rno-u.3   Ryr1   ryanodine receptor 1 
 cfa-u.3   RYR3   ryanodine receptor 3 
 cfa-u.3   RYR1   ryanodine receptor 1 
 cfa-u.3   RYR2   ryanodine receptor 2 
 gga-u.3   101748756   ryanodine receptor 1-like 
 gga-u.3   RYR2   ryanodine receptor 2 
 gga-u.3   RYR3   ryanodine receptor 3 
 dre-u.3   ryr2a   ryanodine receptor 2a (cardiac) 
 dre-u.3   ryr1a   ryanodine receptor 1a (skeletal) 
 dre-u.3   ryr3   ryanodine receptor 3 
 dme-u.3   RyR   Ryanodine receptor 
 cel-u.3   unc-68   Uncharacterized protein 

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Top 50 coexpressed genes to RYR1 (mcc-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mcc500   Starch and sucrose metabolism  3 27 4.12
 mcc564   Glycerophospholipid metabolism  2 100 -
 mcc4072   Phospholipase D signaling pathway  2 168 -
 mcc4014   Ras signaling pathway  2 250 -
 mcc4010   MAPK signaling pathway  3 301 -

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mcc:RYR1 (ryanodine receptor 1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

mcc-u.3
for
RYR1
mcc-r.3
for
RYR1
mcc-u.3
for
RYR3
mcc-u.3
for
RYR2
hsa-u.4
for
RYR3
hsa-u.4
for
RYR2
hsa-u.4
for
RYR1
mmu-u.4
for
Ryr3
mmu-u.4
for
Ryr2
mmu-u.4
for
Ryr1
rno-u.3
for
Ryr2
rno-u.3
for
Ryr3
rno-u.3
for
Ryr1
cfa-u.3
for
RYR3
cfa-u.3
for
RYR1
cfa-u.3
for
RYR2
gga-u.3
for
101748756
gga-u.3
for
RYR2
gga-u.3
for
RYR3
dre-u.3
for
ryr2a
dre-u.3
for
ryr1a
dre-u.3
for
ryr3
dme-u.3
for
RyR
cel-u.3
for
unc-68
1 ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 722202 4.6 2.4
 -1.1
 -1.0





0.3
 -0.8
 -0.3


1.3
 1.1
 0.1
 0.2
 1.2
 -0.7

2 ACTN3 actinin alpha 3 713811 4.1 2.2
 1.0
0.0
 2.1
0.4
 3.2
0.7
 4.9
0.7
 7.0
4.7
 3.1
0.3
 2.4
-0.1
 7.2
6.8
 2.0
-0.5
 2.8
1.9
 7.8
4.3
 0.5
0.1
 2.3
2.2
 2.1
1.0
 1.6
1.3
 2.4
0.1
 4.1
-1.1
 1.6
1.5
 6.2
4.9
 4.0
3.7
 4.1
 4.8
3 TRIM7 tripartite motif containing 7 708324 4.0 2.1
 -0.2
 -0.6





0.3
 -0.6
 0.6
 -0.0
 0.4
 -0.6
 3.6
 -1.1
 0.3




4 CACNA1A calcium voltage-gated channel subunit alpha1 A 718291 4.0 2.1
 2.6
2.3
 2.0
1.5
 2.7
2.6
 4.8
3.0
 8.6
4.4
 4.3
3.7
 4.6
4.5
 9.5
1.7
 4.5
3.4
 2.8
2.5
 7.0
1.3
 2.6
0.9
 2.9
1.9
 1.1
0.8
 2.7
1.7
 4.5
2.1
 3.3
1.3
 3.2
2.9
 6.4
4.5
 4.9
3.7
 9.7
2.2
 7.2
6.7
5 ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 704910 3.8 2.1
 1.1
-0.3
 0.8
0.3
 -0.0
-0.3
 0.9
-0.3
 1.1
0.1
 0.6
0.5
 0.3
-0.4
 0.9
0.2
 0.9
-1.0
 -0.1
-0.6
 -0.0
-0.1
 0.1
-0.1
 1.2
0.4
 0.9
-0.1
 2.6
0.3
 0.9
0.4
 0.7
-0.3
 1.5
1.5
 0.9
0.4
 1.5
0.8
 0.7
 -1.0
6 LOC114676862 uncharacterized LOC114676862 114676862 3.6 1.9





















7 CAPN3 calpain 3 707913 3.6 1.9
 -0.3
 -1.4
 0.9
 -0.4
 1.0
 1.2
 -0.9
 3.6
 -2.0
 0.3
 3.7
 0.6
 2.6
 -0.5
 2.0
 0.0
 2.1
 0.9
0.8
 2.1
1.0
 1.4
0.6

8 DGKG diacylglycerol kinase gamma 699967 3.6 1.9
 3.7
0.3
 3.5
1.6
 4.7
2.8
 3.8
2.0
 1.5
0.4
 3.1
1.7
 3.1
2.8
 0.8
0.5
 2.9
2.4
 3.8
1.6
 1.4
0.5
 0.5
-0.4
 0.2
0.0
 1.3
-0.6
 0.8
-0.0
 2.9
-0.1
 1.9
0.2
 0.4
0.1
 1.7
0.7
 2.7
0.6
 2.4
 0.8
9 ZBTB32 zinc finger and BTB domain containing 32 710216 EGK_10491 3.6 1.9
 0.2
 -0.6
 -1.0
 -0.1
 1.8
 -0.2
 0.4
 1.4








0.4
 0.2
 -0.5
 -0.1
10 LOC114672412 uncharacterized LOC114672412 114672412 3.5 1.9





















11 UNC5A unc-5 netrin receptor A 705285 3.4 1.8
 1.6
1.1
 1.8
1.8
 2.3
1.3
 3.6
2.6
 2.9
1.9
 2.8
2.2
 4.0
2.4
 1.0
0.2
 2.5
2.4
 1.7
0.3
 1.6
0.7
 1.3
0.7
 1.3
0.8
 1.1
0.9
 0.2
0.1
 0.6
0.4
 0.9
0.7
 3.5
3.2
 1.8
1.5
 2.1
2.1
 0.5
 3.3
12 LOC100430472 golgin subfamily A member 2 100430472 3.3 1.8
 0.3
0.3
 -0.2
-0.9
 -0.9
 -0.8
 -0.4
 0.2
 0.3
 -0.7
 0.3
-0.0
 -0.4
-0.5
 0.4
0.3
 0.5
 -0.5
 1.5
 1.6
 -0.8
 -0.6
 0.4
 -0.2
 0.4
 -0.0
 2.4
13 RASGRP4 RAS guanyl releasing protein 4 719595 3.2 1.7
 -0.4
 0.7
 0.4
 -0.6
 6.7
 -0.6
 0.0
 2.8
 -0.8
 -1.2
 1.8
 -0.1
 0.9
 -0.7







14 CLIP1 CAP-Gly domain containing linker protein 1 702137 3.2 1.7
 1.0
0.6
 0.1
-1.3
 0.6
-0.4
 0.4
-0.9
 -0.1
-0.2
 -0.5
-1.2
 0.1
-0.1
 0.8
-0.8
 1.7
-0.8
 1.0
-0.9
 1.3
-0.9
 0.5
0.5
 0.2
-0.6
 0.2
-1.2
 1.1
0.9
 1.0
-0.9
 2.0
-0.6
 0.7
0.3
 0.2
-0.3
 1.2
0.7
 1.5
15 JMJD7 jumonji domain containing 7 707262 3.2 1.7
 -0.3
 0.2
 1.1
 -0.2
 -0.6


-0.4
 -0.2
 -0.5
 -0.3
 -0.7
 -0.0
 -0.5
 -1.1
 -0.4
 0.5
 -0.4
 0.2
 0.5
16 DNASE1L1 deoxyribonuclease 1 like 1 100425571 EGK_21103 3.2 1.7
 -0.2
 -1.4
 -1.0
 -0.6
 1.4
 -0.7
 -1.4
 0.9
 -0.5
 0.0
 1.3
 0.2
 -0.3
 -2.1







17 IGDCC3 immunoglobulin superfamily DCC subclass member 3 709239 3.2 1.7
 0.6
 -0.6
 1.0
 0.1
 1.7
 -1.2
 0.5
 0.3
 0.5
 -0.1
 1.9
 -0.2
 0.8
 -0.8
 -0.4
 -0.9
 -0.3
 0.4
 1.1
 1.8

18 FBXO31 F-box protein 31 695313 3.2 1.7
 -0.6
 0.4
 -0.4
 -0.2
 0.5
 -0.2
 0.2
 0.7
 0.8
 0.4
 0.1
 0.3
 -0.6
 -0.1
 3.9
 -0.7
 0.6
 -0.3
 -0.3
 -0.3

19 SMTNL1 smoothelin like 1 704165 3.2 1.7
 0.4
 -0.4
 0.6
 -0.7
 2.6
 0.4
 -0.8
 5.9
 -1.1
 0.8
 4.1
 -0.2
 0.9
 -1.2
 1.3
 1.0
 1.8




20 LOC106997885 HLA class I histocompatibility antigen, B-37 alpha chain-like 106997885 3.1 1.7





















21 SPRED3 sprouty related EVH1 domain containing 3 715133 3.1 1.7
 1.4
 0.6
 -0.0
 -1.1
 0.7


0.2
 -0.7
 -0.4
 0.2
 1.4
 -0.9







22 NEB nebulin 100430324 3.1 1.7
 0.9
 0.2
 2.5
 1.6
 4.9
 1.1
 0.1
 5.5
 -0.1
 0.9
 5.0
 0.5
-0.3
 3.4
2.3
 0.3
-0.3
 3.5
 -0.6
 3.7
 1.8
 5.1
 4.9

23 PARP10 poly(ADP-ribose) polymerase family member 10 708132 3.1 1.6
 0.3
-0.2
 -0.4
-1.1
 -0.9
 -0.2
 -0.8
 -0.6
 -0.7
 -1.2
 -0.0
 -1.1
 -0.1





-0.2
 -0.7
 0.3

24 PLEKHM2 pleckstrin homology and RUN domain containing M2 701382 3.1 1.6
 -0.4
 -0.2
 0.3
 -0.6
 0.4
 -0.1
 0.4
 -0.3
 0.1
 -0.0
 -1.3
 1.5
 1.0
 -0.6
 2.0
 -0.4
 2.0
 -0.4
 0.2
 -0.4
 0.1
25 SPTBN5 spectrin beta, non-erythrocytic 5 707159 3.0 1.6
 -1.0
 1.5
 0.0
 -0.4
 0.7
 0.1
 0.3
 0.6
 0.2
 0.7
 0.5
 0.2
 1.3
 1.3
 0.3
 1.7
 1.7
 0.6
 -0.3
 1.0
 1.8
 6.5
26 TBKBP1 TBK1 binding protein 1 693913 3.0 1.6
 1.4
 -0.2
 -0.9
 -0.1
 0.6
 -0.5
 0.7
 1.3
 0.7
 1.7
 0.8
 0.2
 1.1
 -0.8
 1.4
 -1.3
 -0.7
 1.5
 -0.3
 -1.1

27 TRIM3 tripartite motif containing 3 710846 EGK_06540 3.0 1.6
 -0.4
 1.1
 -0.8
 -0.4
 -0.3
 1.5
-0.8
 0.9
0.6
 -0.2
-1.0
 1.9
0.4
 1.2
-0.4
 -0.0
-0.7
 -0.5
 -0.8
 -0.4
 1.2
0.5
 1.9
0.8
 1.0
-1.0
 1.7
1.3
 0.5
-0.8
 0.7
0.6
 5.9
 3.0
0.1
28 GANC glucosidase alpha, neutral C 708126 EGK_17402 3.0 1.6
 0.1
-0.2
 0.4
-1.1
 0.8
-1.3
 0.1
-1.2
 0.1
-0.9
 -0.1
-1.0
 -0.5
-0.6
 0.5
-1.0
 -0.4
-0.4
 0.0
-0.4
 1.8
0.9
 1.3
0.1
 0.3
-1.4
 -0.2
-0.5
 0.1
 0.9
 1.9
 2.0
0.2
 0.4
-0.3
 2.1
0.7
 0.4
 2.1
1.0
29 SCN4A sodium voltage-gated channel alpha subunit 4 718194 3.0 1.6
 1.3
1.2
 2.9
1.4
 2.8
2.1
 2.4
1.7
 9.0
3.4
 4.6
2.9
 4.8
3.8
 4.6
1.4
 2.9
2.9
 3.2
1.7
 1.6
1.5
 2.0
1.0
 2.1
1.8
 2.9
2.8
 1.9
0.6
 3.6
3.1
 2.8
1.9
 2.3
2.3
 3.2
2.8
 4.2
4.0
 3.5
30 PGAM2 phosphoglycerate mutase 2 720615 EGK_13739 3.0 1.6
 0.0
-1.0
 0.4
0.1
 0.6
-0.3
 1.2
0.2
 2.7
0.2
 0.7
-0.1
 0.8
0.6
 6.1
-0.1
 0.6
0.0
 -0.5
-1.3
 4.0
0.7
 -0.1
-0.1
 1.2
-0.2
 0.2
 1.8
0.7
 0.3
0.1
 1.5
1.2
 1.1
0.0
 2.5
0.6
 0.7
-1.1
 2.2
-0.0
31 COL8A2 collagen type VIII alpha 2 chain 713447 EGK_00556 3.0 1.6
 0.5
 0.9
 -0.9
 -0.6
 0.3
 -0.0
 -1.1
 0.7
 0.4
 -0.8
 -0.2
 -0.5
 0.6
 -1.0
 -0.2
 0.7
 -0.5
 0.7
 0.9
 0.7

32 KCNC3 potassium voltage-gated channel subfamily C member 3 719568 3.0 1.6
 1.5
0.5
 1.8
0.6
 0.5
-0.8
 0.2
-0.2
 2.9
1.7
 2.5
1.7
 2.8
1.5
 3.7
2.2
 3.8
1.9
 1.2
0.1
 3.8
1.6
 1.9
0.4
 0.8
0.1
 0.1
-0.5
 2.2
0.7
 0.3
0.2
 0.8
0.8
 3.4
3.1
 1.2
0.4
 2.0
1.0
 2.4
0.8
 1.0
0.8
33 P4HA3 prolyl 4-hydroxylase subunit alpha 3 718872 3.0 1.6
 -0.4
 -0.2
 -1.2
 -1.1
 -0.2
 0.6
 0.1
 -0.8
 0.1
 -0.9
 -1.6
 1.0
 -0.5
 -0.4
 1.3
 -0.1
 -0.1




34 SRPK3 SRSF protein kinase 3 100429812 3.0 1.6
 0.5
0.3
 0.7
0.4
 0.2
-0.3
 0.6
0.0
 2.8
-0.2
 1.5
0.8
 1.1
-0.4
 2.6
0.3
 2.2
1.0
 2.1
1.5
 1.7
0.5
 1.0
0.8
 0.7
-0.3
 0.4
0.3
 2.1
-1.1
 2.3
-0.1
 3.0
-0.2
 1.6
0.8
 2.5
2.4
 1.6
1.3
 5.8
0.5
 1.1
35 PRAG1 PEAK1 related, kinase-activating pseudokinase 1 706349 3.0 1.6
 -0.5
 -0.0
 0.4
 -1.1
 -0.2
 -1.3
 0.4
 0.3
 0.3
 0.3
 0.9
 -0.1
 -0.7
 -1.2
 1.0
 -0.3
 -1.0




36 LOC100427657 uncharacterized LOC100427657 100427657 2.9 1.6
 -0.1
-1.5
 0.3
-0.2
 -0.5
 -1.3
 0.5
 -0.6
 -1.0
 -0.8
 -0.8
 -1.2
 0.9
 -0.3
 -0.8
 -0.5
 -0.1
 -0.8
 -0.4
 -0.9
 -1.1
 0.1
 -0.5
37 UNC13D unc-13 homolog D 704431 2.9 1.6
 -1.0
 0.2
 -0.3
 -0.3
 0.4
 -0.2
 0.2
 0.7
 0.1
 -0.3
 0.6
 -1.5
 0.5
 -0.0
 -0.8
 -0.6
 -1.2
 -0.9
 -0.3
 0.5

38 PGM2L1 phosphoglucomutase 2 like 1 718887 EGK_06673 2.9 1.6
 0.1
-1.1
 1.3
-0.8
 0.0
-0.6
 0.3
-0.7
 0.2
-0.3
 0.1
-1.4
 0.9
-1.0
 -0.1
-0.2
 0.7
-0.2
 0.9
-0.9
 0.4
-1.1
 0.6
0.2
 -1.1
-1.2
 -0.0
-0.2
 2.3
-1.1
 -0.4
-1.0
 -0.2
-1.2
 -0.4
-0.5
 -0.3
-0.4
 0.1
-0.1
 0.7
-0.0
 -0.2
39 CCM2L CCM2 like scaffold protein 107000439 2.9 1.6
 -0.1
 0.4
 0.9
 1.1
 2.6


0.2
 0.5
 0.4
 1.3
 -0.8
 -0.3
 1.1
 0.7
 -1.9
 1.1
 -0.6
 -1.2

40 C19H19orf44 chromosome 19 C19orf44 homolog 719544 2.9 1.6
 -0.9
 0.6
 -0.1
 0.1
 0.4
 0.4
 0.1
 0.8
 -1.1
 0.1
 -0.5
 -1.1
 0.4
 -0.2
 -1.3
 0.4
 0.2
 -1.6
 -0.9
 -0.5

41 ADAM11 ADAM metallopeptidase domain 11 100430916 2.9 1.6
 0.4
 0.3
 -0.1
 1.6
 1.5
 1.1
 2.4
 1.1
 2.2
 0.7
 1.2
 0.4
 0.6
 -0.8
 2.9
 -0.1
 0.3
 0.7
 1.5
 1.3

42 KIF5A kinesin family member 5A 711936 EGK_03842 2.9 1.6
 0.1
-0.7
 4.6
1.4
 1.2
1.0
 1.8
1.0
 2.4
0.8
 1.1
1.0
 1.4
1.1
 0.8
0.4
 2.0
0.9
 2.1
1.0
 0.8
0.1
 1.7
0.8
 -0.1
-0.5
 0.4
0.3
 2.3
0.2
 1.5
0.4
 1.0
0.1
 2.6
2.2
 0.9
0.2
 2.8
0.9
 1.0
 2.1
43 PCBP4 poly(rC) binding protein 4 699225 EGK_11579 2.9 1.6
 0.2
-0.2
 -0.6
-0.8
 -0.4
-0.8
 -0.1
-0.4
 1.3
-0.1
 -0.3
-0.6
 -0.1
-0.1
 -0.4
-0.4
 -0.4
-1.0
 0.2
-0.2
 0.5
0.0
 1.3
-0.0
 -0.1
-0.4
 0.5
0.5
 1.2
0.9
 2.3
1.2
 1.3
-0.0
 2.1
1.0
 0.5
0.0
 1.5
0.3
 -0.1
 -0.5
44 PYGM glycogen phosphorylase, muscle associated 717451 EGK_06046 2.9 1.6
 0.4
-0.9
 1.1
-0.1
 1.2
0.6
 1.0
0.2
 4.5
0.2
 0.6
0.6
 1.7
1.5
 4.6
-0.6
 0.6
0.6
 0.1
-0.7
 4.4
0.3
 0.2
-0.1
 1.3
-1.1
 0.1
0.0
 0.1
-0.3
 3.2
-1.2
 -0.4
-0.8
 2.3
0.8
 2.2
1.8
 2.7
0.9
 2.2
 0.6
45 SMIM10L2A small integral membrane protein 10 like 2A 106995328 2.9 1.6
 2.1
-0.2
 0.3
-0.0
 1.0
-0.2
 1.4
1.0
 1.1
0.8
 0.0
-0.3
 1.0
-0.6
 -0.2
-0.7
 -0.5
-0.8
 -0.6
-1.1
 0.0
-0.3
 0.1
-0.6
 -0.7
-1.9
 1.4
-0.9
 -0.7
 -0.3
 -0.1
 -0.9
 -1.1
 -0.4

46 JPH3 junctophilin 3 704611 2.9 1.6
 1.1
0.8
 0.6
0.5
 1.6
0.9
 3.4
1.6
 1.4
1.4
 2.0
1.3
 1.7
1.4
 3.0
1.6
 3.3
1.7
 2.2
0.2
 2.8
0.7
 1.1
0.0
 1.6
0.9
 1.5
0.1
 2.2
1.7
 2.7
0.1
 1.8
0.9
 2.9
2.4
 3.1
2.1
 9.7
5.4
5.0
47 ASRGL1 asparaginase and isoaspartyl peptidase 1 718871 EGK_06117 2.9 1.6
 1.2
 0.1
 0.7
 -1.0
 0.5
 0.2
 -0.6
 1.1
 0.1
 -1.2
 0.4
 0.5
 0.0
 -1.0
 -1.0
 0.4
 -0.5
 0.2
-0.3
 0.4
-1.6
 1.3
-0.3
 -0.5
48 PLA2G4B phospholipase A2 group IVB 100533113 2.9 1.6
 -1.1
-1.2
 0.2
-0.1
 1.2
0.7
 0.9
0.9
 1.9
1.0
 2.0
-0.1
 2.9
0.7
 2.3
0.4
 0.5
0.2
 1.6
0.3
 0.8
0.7
 0.4
-0.1
 1.0
0.4
 1.5
-0.3
 -0.2
-0.7
 2.7
1.8
 1.6
0.7
 1.0
-0.1
 1.0
0.6
 0.4
0.2

49 PHTF2 putative homeodomain transcription factor 2 693552 2.9 1.6
 2.0
0.1
 0.4
-0.7
 -0.4
-1.1
 0.3
-0.5
 1.2
-0.5
 0.3
0.2
 1.7
-0.3
 1.7
-0.5
 -0.1
-0.4
 2.7
1.6
 0.6
0.0
 -0.1
-0.2
 0.5
-0.6
 -0.5
-2.1
 0.2
-0.6
 0.2
-0.1
 2.6
 -0.1
-0.4
 0.9
-0.4
 0.6
0.6
 1.5
50 LOC106993079 uncharacterized LOC106993079 106993079 2.8 1.5





















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