Orthologous genes in OrthoFinder**

Species Gene Description
 mcc-u.3   CD2   CD2 molecule 
 mcc-r.3   CD2   CD2 molecule 
 hsa-u.4   CD2   CD2 molecule 
 mmu-u.4   Cd2   CD2 antigen 
 rno-u.3   Cd2   Cd2 molecule 
 cfa-u.3   CD2   CD2 molecule 
 gga-u.3   CD2   CD2 molecule 

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Top 50 coexpressed genes to CD2 (mcc-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mcc4660   T cell receptor signaling pathway  11 100 6.23
 mcc4658   Th1 and Th2 cell differentiation  10 87 6.59
 mcc4659   Th17 cell differentiation  10 103 6.16
 mcc5166   Human T-cell leukemia virus 1 infection  9 219 6.51
 mcc5235   PD-L1 expression and PD-1 checkpoint pathway in cancer  8 87 6.59

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mcc:CD2 (CD2 molecule) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

mcc-u.3
for
CD2
mcc-r.3
for
CD2
hsa-u.4
for
CD2
mmu-u.4
for
Cd2
rno-u.3
for
Cd2
cfa-u.3
for
CD2
gga-u.3
for
CD2
1 LOC716034 signal-regulatory protein gamma 716034 13.0 6.7
 9.8
-0.2
 1.8
1.8
 0.8
 2.7
1.4
 1.3
0.8
2 CD3D CD3d molecule 699582 12.0 6.2
 19.4
 13.6
 9.4
 9.1
 3.0
3 CLEC2D C-type lectin domain family 2 member D 717228 11.8 6.2
 5.8
4.0
 5.7
4.2
 5.7
1.6
 4.1
3.8
 1.8
0.6
4 CD3G CD3g molecule 705270 EGK_06952 11.7 6.1
 19.5
 12.7
 7.9
 9.3
5 CD3E CD3e molecule 699467 EGK_06950 10.7 5.6
 20.9
 10.1
 9.6
 9.2
 1.9
6 TRAT1 T cell receptor associated transmembrane adaptor 1 705946 10.4 5.4
 15.5
 4.6
4.9
 2.7
7 CD40LG CD40 ligand 574160 10.3 5.4
 12.8
 5.0
3.4
 3.7
8 PYHIN1 pyrin and HIN domain family member 1 719241 10.2 5.3
 9.7
2.9
 3.0
0.6
 1.3
 0.9
0.1
9 SH2D1A SH2 domain containing 1A 574156 EGK_20903 9.6 5.0
 13.9
 10.4
6.0
 2.0
10 IL2RB interleukin 2 receptor subunit beta 696331 9.6 5.0
 8.5
 8.3
 6.9
 3.3
 1.8
11 LOC106999340 immunoglobulin kappa light chain 106999340 9.6 5.0


9.3
12 TIGIT T cell immunoreceptor with Ig and ITIM domains 710941 9.1 4.8
 10.4
 3.5
1.7
13 LOC705095 T cell receptor gamma constant 2 705095 8.8 4.6
 9.7

1.9
 2.9
2.4
14 P2RY10 purinergic receptor P2Y, G-protein coupled, 10 707388 EGK_20675 8.7 4.6
 8.9
 7.6
2.6
 6.0
1.0
 1.6
 1.4
-0.6
15 LOC703029 immunoglobulin lambda-1 light chain-like 703029 8.7 4.6




16 LCK LCK proto-oncogene, Src family tyrosine kinase 717704 EGK_00506 8.5 4.4
 9.3
3.4
 8.0
6.5
 6.3
4.6
 8.0
2.1
 2.7
1.8
17 ICOS inducible T cell costimulator 705788 8.4 4.4
 14.8
 6.0
4.0
 2.6
18 CXCR6 C-X-C motif chemokine receptor 6 713829 8.3 4.3
 9.2
 6.4
 5.5
 2.3
19 UBASH3A ubiquitin associated and SH3 domain containing A 722456 8.3 4.3
 11.6
0.2
 5.7
-0.1
 1.0
 4.7
1.3
 2.0
0.1
20 CXCR3 C-X-C motif chemokine receptor 3 699438 8.0 4.2
 8.8
 6.0
 6.4
 4.6
21 LOC106999939 uncharacterized LOC106999939 106999939 7.9 4.2




22 GPR174 G protein-coupled receptor 174 707800 7.8 4.1
 10.9
 6.7
3.9
 2.4
23 ITK IL2 inducible T cell kinase 715471 EGK_17070 7.6 4.0
 14.0
 8.0
 5.6
 4.2
 2.0
24 GZMK granzyme K 705477 EGK_16487 7.6 4.0
 15.2
12.7
 6.5
5.2
 4.8
2.6
 5.5
3.6
 3.0
1.4
25 CD6 CD6 molecule 695183 7.5 3.9
 12.1
 9.0
 5.3
 4.3
 1.0
26 GFI1 growth factor independent 1 transcriptional repressor 706481 7.5 3.9
 5.3
 3.0
1.8
 3.3
27 LOC106995333 uncharacterized LOC106995333 106995333 7.5 3.9




28 SIT1 signaling threshold regulating transmembrane adaptor 1 697087 EGK_07571 7.4 3.9
 8.3
 8.3
 6.7
 5.8
29 PRF1 perforin 1 710241 7.4 3.9
 9.7
 6.5
 6.7
 2.9
 0.8
30 LAT linker for activation of T cells 704656 7.3 3.8
 4.6
 6.8
 5.8
 3.9
31 THEMIS thymocyte selection associated 711575 7.2 3.8
 15.4

4.2
 2.6
32 CD5 CD5 molecule 695249 7.2 3.8
 12.1
 9.1
 8.0
 5.1
 1.4
33 LOC114675520 T-cell surface glycoprotein CD5-like 114675520 7.2 3.8
 12.1
 9.1
 8.0
 5.1
 1.4
34 SLAMF6 SLAM family member 6 719728 7.2 3.8
 9.8
7.6
 6.6
4.1
 4.6
1.7
 3.9
3.5
35 SLAMF1 signaling lymphocytic activation molecule family member 1 719747 7.2 3.8
 9.9
 4.3
3.4
 2.7
36 SKAP1 src kinase associated phosphoprotein 1 697043 EGK_08473 7.0 3.7
 6.1
 7.9
 7.2
 5.8
 0.4
37 GPR171 G protein-coupled receptor 171 709960 6.9 3.6
 12.5
 5.1
 4.5
 5.3
 0.3
38 TBX21 T-box transcription factor 21 694044 6.9 3.6
 7.0
 5.5
 5.9
 1.8
 2.2
39 SEPTIN1 septin 1 710226 6.8 3.6
 8.8
0.8
 5.2
0.8
 4.2
0.4
 5.4
1.6
 2.4
1.5
40 LOC698785 uncharacterized LOC698785 698785 6.8 3.6




41 PVRIG PVR related immunoglobulin domain containing 711659 6.7 3.5
 5.2

4.5
42 GIMAP8 GTPase, IMAP family member 8 713236 EGK_14329 6.6 3.5
 4.1
 4.2
 2.2
 3.4
43 LY9 lymphocyte antigen 9 720255 6.6 3.4
 9.8
7.6
 6.6
4.1
 4.6
1.7
 3.9
3.5
44 CD96 CD96 molecule 706836 6.5 3.4
 11.3
 5.5
 8.5
 7.0
45 NKG7 natural killer cell granule protein 7 719624 EGK_10964 6.4 3.4
 9.0
 7.4
 5.4
 1.7
46 TRAF3IP3 TRAF3 interacting protein 3 712895 EGK_01696 6.4 3.3
 8.0
 4.6
 5.9
 5.4
 1.4
47 GIMAP7 GTPase, IMAP family member 7 713436 EGK_14330 6.4 3.3
 9.0
 10.6
3.5
 8.1
3.2
 4.2
48 NFATC2 nuclear factor of activated T cells 2 710601 6.3 3.3
 3.0
 1.6
 1.1
 0.6
 0.3
49 LTA lymphotoxin alpha 715425 EGK_14704 6.2 3.3
 4.2
 4.1
-0.2
50 TBC1D10C TBC1 domain family member 10C 712270 6.1 3.2
 4.2
 6.9
 4.5
 1.7
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