Orthologous genes in OrthoFinder**

Species Gene Description
 cel-u.3   pac-1   GTPase-activating protein pac-1;Rho-GAP domain-containing protein 
 cel-r.3   pac-1   GTPase-activating protein pac-1;Rho-GAP domain-containing protein 
 cel-m.5   pac-1   GTPase-activating protein pac-1;Rho-GAP domain-containing protein 
 hsa-u.4   ARHGAP23   Rho GTPase activating protein 23 
 mmu-u.4   Arhgap23   Rho GTPase activating protein 23 
 rno-u.3   Arhgap23   Rho GTPase activating protein 23 
 gga-u.3   ARHGAP23   Rho GTPase activating protein 23 
 dre-u.3   arhgap23a   Rho GTPase activating protein 23a 
 dre-u.3   arhgap23b   Rho GTPase activating protein 23b 
 mcc-u.3   ARHGAP23   Rho GTPase activating protein 23 
 cfa-u.3   ARHGAP23   Rho GTPase activating protein 23 
 spo-u.3   seh1   nucleoporin Seh1 

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Top 50 coexpressed genes to pac-1 (cel-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 cel310   Lysine degradation  2 37 2.15
 cel4350   TGF-beta signaling pathway  2 42 2.04
 cel4068   FoxO signaling pathway  1 60 -
 cel3008   Ribosome biogenesis in eukaryotes  1 83 -
 cel4144   Endocytosis  2 110 -

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cel:pac-1 (GTPase-activating protein pac-1;Rho-GAP domain-containing protein) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

cel-u.3
for
pac-1
cel-r.3
for
pac-1
cel-m.5
for
pac-1
hsa-u.4
for
ARHGAP23
mmu-u.4
for
Arhgap23
rno-u.3
for
Arhgap23
gga-u.3
for
ARHGAP23
dre-u.3
for
arhgap23a
dre-u.3
for
arhgap23b
mcc-u.3
for
ARHGAP23
cfa-u.3
for
ARHGAP23
spo-u.3
for
seh1
1 mig-38 Abnormal cell migration protein 38 178082 CELE_F40F11.2 11.4 6.3
 4.7
 -0.1
 1.9
 1.6
 -0.7
 0.6
 0.2
 -0.8
 0.5
2 egl-27 Egg-laying defective protein 27 174121 CELE_C04A2.3 8.9 5.4
 3.3
 0.9
 0.1
 -0.3
 0.3
 1.7
 1.6
 -0.5
 1.3
 0.3
3 rin-1 VPS9 domain-containing protein 3565509 CELE_C48G7.3 8.6 4.2
 4.1
 3.1
2.0
 1.8
1.6
 2.6
1.8
 -0.2
-1.4
 1.7
0.7
 0.4
-0.1
 0.9
0.7
 2.1
0.4
4 cbp-1 Protein cbp-1 176380 CELE_R10E11.1 8.4 4.7
 3.4
 1.0
0.4
 0.5
0.5
 1.4
-0.1
 -0.5
-0.9
 1.6
0.5
 -0.3
-0.8
 0.5
-0.9
 1.3
0.6
 -1.2
5 mrck-1 Myotonic dystrophy-Related, Cdc42-binding Kinase homolog;Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase mrck-1 179013 CELE_K08B12.5 8.4 4.8
 3.3
 2.9
2.0
 4.4
2.7
 3.7
3.5
 2.6
1.4
 5.7
3.7
 1.3
0.4
 1.4
0.9
 3.7
3.6
6 kin-4 Non-specific serine/threonine protein kinase 178068 CELE_C10C6.1 8.3 4.6
 3.5
 0.2
-1.2
 1.6
0.9
 2.1
1.5
 3.8
1.0
 2.5
1.3
 0.5
-0.4
 1.1
-1.1
 2.3
-0.6
 0.0
7 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like 174685 CELE_C09D8.1 8.2 4.4
 3.5
 1.5
0.9
 1.1
0.5
 2.6
0.7
 2.4
2.3
 2.7
1.8
 0.6
0.0
 1.0
0.6
 1.0
0.7
 1.3
8 lsy-12 Histone acetyltransferase 3565873 CELE_R07B5.9 8.1 3.5
 4.4








9 hmr-1 Cadherin-related hmr-1 173007 CELE_W02B9.1 7.8 4.0
 3.6


0.6
0.0
 -0.2
-0.6
 0.9
0.2


10 par-3 Partitioning defective protein 3 175783 CELE_F54E7.3 7.7 4.6
 2.9
 1.9
0.1
 0.4
-0.8
 1.3
0.8
 -0.2
-1.2
 2.0
1.8
 0.1
0.1
 1.1
0.5
 2.7
0.6
 0.6
11 clr-1 Protein-tyrosine-phosphatase;Receptor-type tyrosine-protein phosphatase 3565419 CELE_F56D1.4 7.6 4.3
 3.0
 -0.1
 -1.6
 -0.1
 -1.4
 0.7
 -0.5
 -0.7
 -1.0
12 mask-1 Ankyrin repeat and KH domain-containing protein mask-1 177927 CELE_R11A8.7 7.5 4.2
 3.0
 -0.5
-0.5
 1.3
-1.2
 0.9
0.1
 -0.1
-0.3
 1.0
 0.2
 0.3
-1.3
 0.3
-0.0
13 let-526 ARID domain-containing protein 3565337 CELE_C01G8.9 7.4 4.0
 3.2
 0.8
0.3
 1.4
 3.3
3.1
 0.6
-1.0
 1.5
1.1
 0.3
-0.5
 0.8
-0.3
 0.7
0.6
14 ark-1 Ack-related non-receptor tyrosine kinase 178218 CELE_C01C7.1 7.3 4.1
 3.0








15 cyld-1 USP domain-containing protein 176401 CELE_F40F12.5 7.3 4.0
 3.1
 1.8
 -0.1
 0.4
 -0.3
-0.5
 1.8
0.3
 1.5
1.2
 -1.0
 -0.9
 0.7
16 abts-1 Anion exchange protein 172613 CELE_F52B5.1 7.2 3.5
 3.5
 1.2
1.0
 1.3
0.9
 1.2
0.8
 1.1
0.8
 1.8
1.7
 2.3
2.2
 1.3
1.2
 1.5
0.6
 0.1
0.1
17 gei-8 Nuclear receptor corepressor 1 176145 CELE_C14B9.6 7.2 3.5
 3.5
 3.4
-0.7
 2.4
0.4
 2.3
0.3
 0.8
-0.3
 1.5
0.8
 0.3
0.2
 1.9
-1.0
 1.7
0.3
 -0.7
18 daf-19 RFX-like transcription factor daf-19;RFX-type winged-helix domain-containing protein 174577 CELE_F33H1.1 7.1 3.7
 3.2
 1.8
1.1
 3.2
0.3
 0.9
-0.0
 0.3
-1.5
 1.8
1.0
 1.1
0.4
 0.8
0.5
 1.7
0.7
 -0.5
19 dpy-21 Lysine-specific demethylase 9 180176 CELE_Y59A8B.1 7.1 4.9
 2.0
 -0.3
-1.9
 0.0
-0.7
 1.0
0.7
 -0.4
-0.4
 -0.9
 -0.1
 0.1
-1.4
 0.2
-0.7
20 tlk-1 Protein kinase domain-containing protein;Serine/threonine-protein kinase tousled-like 1 176369 CELE_C07A9.3 6.8 4.4
 2.2
 -0.0
-0.4
 1.1
-0.2
 0.9
0.7
 -0.9
-1.1
 0.4
-0.4
 -0.1
-0.2
 -0.0
-1.0
 -0.1
-0.4
21 soap-1 Sorting Of Apical Proteins 179109 CELE_C13F10.4 6.8 3.5
 3.0
 0.0
-0.7
 1.1
0.6
 0.8
0.5
 -0.2
-0.4
 1.5
-0.9
 -0.6
-1.0
 -0.2
-0.9
 0.3
-0.4
 -0.3
22 T04C9.1 Uncharacterized protein 175849 CELE_T04C9.1 6.8 4.2
 2.4
 1.0
-0.4
 0.7
-0.6
 0.7
0.4
 1.5
0.7
 1.3
 0.3
 0.3
-1.6
 0.9
-0.4
23 tol-1 TIR domain-containing protein 171635 CELE_C07F11.1 6.7 3.7
 2.8
 -0.3
-0.6
 -0.2
-0.3
 -0.0
-0.9
 0.7
-0.1
 0.5
0.3
 0.1
-0.2
 -0.4
-0.5
 -2.3
24 rig-4 Protein sidekick homolog 177597 CELE_Y42H9B.2 6.7 3.1
 3.4
 0.3
-0.4
 0.9
-0.5
 2.2
1.1
 1.5
1.3
 1.7
1.7
 1.5
1.2
 0.9
0.8
 1.8
0.3
25 Y54G2A.26 Uncharacterized protein 177079 CELE_Y54G2A.26 6.6 3.6
 2.9








26 set-16 Histone-lysine N-methyltransferase 176802 CELE_T12D8.1 6.5 3.2
 3.2
 -1.2
 -0.5
 0.7
 -0.7
 3.2
1.2
 0.5
-1.6
 0.4
 1.3
27 hgap-2 Heterodimeric GTPase Activating Protein subunit 3564922 CELE_D2085.5 6.5 4.4
 1.9
 -0.1
 -0.9
 0.7
 -0.3
 4.3
 -1.0
 -0.1
 0.5
28 lin-59 putative histone-lysine N-methyltransferase lin-59 266825 CELE_T12F5.4 6.5 4.6
 1.8
-0.5
 -0.6
 0.4
 2.9
 -0.7
 -1.3
 2.4
29 wnk-1 Serine/threonine-protein kinase WNK 177743 CELE_C46C2.1 6.4 2.8
 3.5
 1.3
-1.3
 0.8
-0.2
 -0.1
-1.0
 1.5
 2.1
1.6
 1.0
0.3
 -0.7
-1.2
 -0.3
-0.6
 1.6
30 cnt-2 Arf-GAP with ANK repeat and PH domain-containing protein cnt-2 176490 CELE_Y39A1A.15 6.4 3.5
 2.7
 2.2
0.4
 2.6
1.3
 2.0
1.8
 4.2
0.7
 3.1
0.4
 0.7
0.1
 0.9
0.6
 1.5
1.1
31 mdt-15 Mediator of RNA polymerase II transcription subunit 15 175817 CELE_R12B2.5 6.4 4.0
 2.2
 1.3
 1.0
 0.5
 0.3
 0.0
 -0.4
 2.2
 1.0
 1.7
32 F41H10.3 Uncharacterized protein 177319 CELE_F41H10.3 6.4 3.9
 2.3








33 pkc-1 Protein kinase C;Protein kinase C-like 1B 179649 CELE_F57F5.5 6.3 3.5
 2.7
 0.4
0.4
 2.5
1.0
 0.9
0.6
 0.2
 3.5
3.2
 1.6
0.3
 1.5
0.5
 1.1
0.4
 0.5
34 sax-7 Fibronectin type-III domain-containing protein 177602 CELE_C18F3.2 6.3 4.2
 1.9
 -2.1
 -1.4
 -0.7
 -0.3
 2.4
 0.3
 0.2
 -0.2
35 unc-40 Uncharacterized protein 172233 CELE_T19B4.7 6.3 3.3
 2.8
 0.5
-0.4
 -0.3
-0.9
 1.7
0.9
 0.8
 1.7
1.0
 -0.3
-1.4
 0.0
-0.4
 0.6
0.0
36 lin-13 Zinc finger protein lin-13 176083 CELE_C03B8.4 6.3 3.4
 2.7








37 pdzd-8 PDZ Domain containing 177716 CELE_C53B4.4 6.2 2.8
 3.3
 1.4
 0.2
 1.0
 -0.5
 -1.3
 -0.7
 0.9
 0.2
38 lst-6 Lateral Signaling Target 174146 CELE_C52E12.4 6.2 3.1
 3.0
 0.3
0.1
 3.3
-0.4
 2.2
1.7
 1.6
-0.0
 2.9
-1.2
 1.3
0.6
 0.9
-1.1
 0.7
0.0
39 cdh-4 Cadherin-4 175590 CELE_F25F2.2 6.1 2.7
 3.2
 2.1
1.3
 0.7
0.1
 1.5
0.3
 0.7
-0.1
 2.2
1.6
 2.9
0.8
 0.6
0.3
 1.6
0.6
40 T11G6.5 Uncharacterized protein 177976 CELE_T11G6.5 6.1 4.1
 1.9
-1.3
 -0.2
 0.2
 -0.5
 -0.3
 0.2
 1.3
41 vab-1 Ephrin receptor 1 173794 CELE_M03A1.1 6.1 2.7
 3.1
 4.7
1.2
 2.3
1.8
 3.6
1.5
 3.8
3.0
 2.4
2.0
 2.6
1.1
 1.6
1.4
 4.1
2.2
42 chd-7 Chromodomain and Helicase Domain protein 172079 CELE_T04D1.4 6.0 2.8
 3.0
 0.2
 0.6
0.2
 1.1
0.9
 1.7
1.4
 1.1
0.9
 0.1
-0.0
 0.8
0.8
 1.1
1.0
43 daf-4 Cell surface receptor daf-4;Receptor protein serine/threonine kinase;Serine/threonine-protein kinase receptor 175781 CELE_C05D2.1 6.0 2.2
 3.6
 -1.1
-1.4
 -0.3
-1.0
 0.2
-0.0
 1.1
0.9
 2.1
1.7
 1.5
0.7
 1.8
0.1
 0.4
-0.5
44 pacs-1 Phosphofurin Acidic Cluster Sorting protein homolog 179304 CELE_T18H9.7 6.0 2.8
 3.1
 2.1
0.2
 2.4
2.1
 4.0
1.3
 1.4
1.4
 3.2
2.2
 1.2
1.0
 0.5
-0.0
 3.1
1.4
45 pbrm-1 HMG box domain-containing protein 172504 CELE_C26C6.1 6.0 3.7
 2.1
 1.0
 -0.1
 1.5
 -0.1
 0.6
0.5
 1.3
0.9
 -0.0
 0.1
46 F31C3.3 Fmp27_GFWDK domain-containing protein 173375 CELE_F31C3.3 6.0 3.0
 2.8
 0.8
 -1.2
 -0.6
 0.9

-0.2
 -0.4
47 pqe-1 Putative RNA exonuclease pqe-1 175731 CELE_F52C9.8 5.9 3.1
 2.7








48 nhr-66 Nuclear Hormone Receptor family 177618 CELE_T09A12.4 5.9 3.7
 2.1








49 swsn-7 SWI/SNF nucleosome remodeling complex component 174286 CELE_C08B11.3 5.9 2.6
 3.1
 -1.1
 1.0
 1.3
 -1.7
 1.4
 -0.6
 -0.6
 -0.2
 0.1
50 apr-1 Adenomatous polyposis coli protein-related protein 1 172591 CELE_K04G2.8

1.6
1.3
 2.9
0.1
 0.9
0.5
 1.9
1.1
 2.2
1.8
 1.2
0.4
 1.1
-1.6
 2.4
-0.1
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