Orthologous genes in OrthoFinder**

Species Gene Description
 dre-r.3  sesn1  sestrin 1 
 dre-u.3  sesn1  sestrin 1 
 dre-u.3  sesn2  sestrin 2 
 dre-u.3  sesn4  sestrin 4 
 dre-u.3  sesn3  sestrin 3 
 hsa-u.4  SESN3  sestrin 3 
 hsa-u.4  SESN1  sestrin 1 
 hsa-u.4  SESN2  sestrin 2 
 mmu-u.4  Sesn3  sestrin 3 
 mmu-u.4  Sesn1  sestrin 1 
 mmu-u.4  Sesn2  sestrin 2 
 rno-u.3  Sesn3  sestrin 3 
 rno-u.3  Sesn2  sestrin 2 
 rno-u.3  Sesn1  sestrin 1 
 gga-u.3  SESN2  sestrin 2 
 gga-u.3  SESN4  sestrin 4 
 gga-u.3  SESN3  sestrin 3 
 mcc-u.3  SESN2  sestrin 2 
 mcc-u.3  SESN1  sestrin 1 
 mcc-u.3  SESN3  sestrin 3 
 cfa-u.3  SESN2  sestrin 2 
 cfa-u.3  SESN3  sestrin 3 
 cfa-u.3  SESN1  sestrin 1 
 cel-u.3  sesn-1  Sestrin homolog 

close


Top 50 coexpressed genes to sesn1 (dre-r.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre4068   FoxO signaling pathway  8 173 6.68
 dre4140   Autophagy - animal  7 191 6.39
 dre4910   Insulin signaling pathway  5 172 4.20
 dre4150   mTOR signaling pathway  4 185 2.96
 dre4137   Mitophagy - animal  3 90 2.85

close


dre:sesn1 (sestrin 1) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID LINK Target Reference

dre-r.3
for
sesn1


dre-u.3
for
sesn1


dre-u.3
for
sesn2


dre-u.3
for
sesn4


dre-u.3
for
sesn3


hsa-u.4
for
SESN3


hsa-u.4
for
SESN1


hsa-u.4
for
SESN2


mmu-u.4
for
Sesn3


mmu-u.4
for
Sesn1


mmu-u.4
for
Sesn2


rno-u.3
for
Sesn3


rno-u.3
for
Sesn2


rno-u.3
for
Sesn1


gga-u.3
for
SESN2


gga-u.3
for
SESN4


gga-u.3
for
SESN3


mcc-u.3
for
SESN2


mcc-u.3
for
SESN1


mcc-u.3
for
SESN3


cfa-u.3
for
SESN2


cfa-u.3
for
SESN3


cfa-u.3
for
SESN1


cel-u.3
for
sesn-1

1 mknk2b MAPK interacting serine/threonine kinase 2b 373121 6.1 11.9
2.5
1.1
4.4
3.4
0.9
0.4
2.0
-0.3
2.2
0.9
6.4
0.8
1.1
-1.8
3.2
1.1
2.5
2.3
-0.6
-1.5
2.0
0.3
4.6
0.6
5.9
1.0
2.9
0.2
1.7
0.2
3.3
-1.1
2.0
-0.1
1.2
-0.4
2.7
0.6
1.0
-1.4
1.8
0.3
-0.3
2 foxo3b forkhead box O3b 30296 5.2 10.0
-0.3
-0.9
5.0
2.8
2.2
0.6
2.5
3.4
2.2
1.9
7.5
2.8
2.6
0.4
1.9
2.8
2.4
3.2
3.7
1.0
5.9
0.1
1.2
6.7
2.4
3 arrdc2 arrestin domain containing 2 335206 4.5 8.6
2.1
1.1
2.2
1.6
2.0
1.6
2.5
1.6
3.8
2.5
2.5
1.1
1.5
0.2
5.9
5.0
2.6
0.9
-0.2
-0.4
1.4
-0.1
5.5
3.1
4.6
3.4
3.5
1.9
1.9
0.5
2.9
2.0
3.0
2.1
0.3
0.0
2.8
1.4
2.1
1.5
4.4
2.8
2.9
1.9
4 sesn4 sestrin 4 100149048 4.2 8.1
-0.0
-0.6
8.1
1.7
2.3
1.7
4.5
0.8
4.5
3.3
3.3
0.8
1.8
0.5
1.8
-1.9
0.5
-1.9
0.3
0.1
0.1
-1.4
0.3
-1.4
2.8
-0.7
1.2
0.4
0.4
0.3
0.1
-0.1
0.8
0.1
0.8
-0.1
-1.0
-1.2
2.1
-1.2
2.1
-1.0

5 si:ch211-260e23.9 si:ch211-260e23.9 555795 4.0 7.8






















6 lpin1a lipin 1a 799099 4.0 7.8
2.2
0.5
3.8
1.6
1.3
0.9
1.3
0.5
1.0
0.8
1.3
0.9
0.6
0.2
3.6
2.4
2.4
2.0
1.5
0.5
0.8
0.6
4.3
1.6
1.4
0.7
2.6
0.2
1.1
-0.2
0.6
0.1
3.0
-0.5
1.9
0.3
2.3
0.4
1.9
0.5
1.6
1.0
0.7
7 bbc3 BCL2 binding component 3 751763 4.0 7.7






















8 bada BCL2 associated agonist of cell death a 564921 3.5 6.7
1.5
0.7
6.0
1.0
0.7
0.4
-0.2
-0.6
-0.5
0.2
-0.2
-0.0
0.5
0.2
0.5



-0.7
-1.2
0.7
-0.0
-0.3
-0.5

9 ccng2 cyclin G2 266794 3.4 6.4
1.2
-0.4
3.9
2.1
3.3
0.5
3.7
2.5
6.9
3.5
2.5
1.4
2.2
0.5
3.4
0.4
5.0
-0.3
1.3
-0.3
1.0
-0.2
6.0
0.4
2.2
0.5
2.6
-1.3
2.3
0.5
2.4
-0.5
3.4
2.0
2.8
1.0
1.8
0.1
1.9
0.4
2.3
1.4

10 pdk2a pyruvate dehydrogenase kinase 2a 794083 3.3 6.4
0.2
-0.2
2.4
2.0
2.5
1.2
2.7
1.1
2.7
1.0
0.3
-0.4
1.8
1.1
3.9
2.9
1.5
0.7
1.9
1.1
0.8
-0.0
4.8
3.7
2.2
1.8
5.4
2.7
1.4
0.7
0.8
0.8
2.2
2.1
0.9
0.7
0.7
-0.4
1.3
0.3
2.5
1.4
1.0
11 pdk2b pyruvate dehydrogenase kinase 2b 393971 3.3 6.3
0.2
-0.2
2.4
2.0
2.5
1.2
2.7
1.1
2.7
1.0
0.3
-0.4
1.8
1.1
3.9
2.9
1.5
0.7
1.9
1.1
0.8
-0.0
4.8
3.7
2.2
1.8
5.4
2.7
1.4
0.7
0.8
0.8
2.2
2.1
0.9
0.7
0.7
-0.4
1.3
0.3
2.5
1.4
1.0
12 slc25a43 solute carrier family 25 member 43 796731 3.3 6.3
-0.6
1.2
-0.4
-1.0
-1.0
0.1






-0.2
-0.5
0.6
-0.8
-0.2
-1.3
0.6
0.0
-1.4

13 ulk2 unc-51 like autophagy activating kinase 2 100329702 3.2 6.1
0.3
-1.3
3.5
1.6
0.6
-0.6
0.9
0.4
1.2
0.3
3.7
-0.8
1.6
0.0
2.7
2.1
2.5
-2.6
0.1
0.1
0.3
-1.4
4.3
1.5
3.4
0.3
1.1
0.9
1.5
0.9
3.0
0.1
1.3
0.3
1.7
0.2
2.4
0.5
2.6
-1.2
1.3
0.5
0.4
14 ddit4 DNA-damage-inducible transcript 4 378866 3.1 6.0
7.7
0.5
1.1
-1.4
-0.5
-0.7
1.2
0.9
3.0
0.5
8.6
0.2
2.3
2.1
3.0
-0.5
5.9
2.5
0.7
-0.1
2.2
-1.1
3.6
-0.3
1.9
0.1
1.7
3.9
3.5
-0.4
1.6
0.0
1.4
0.8
2.9
0.8

15 klhl38b kelch-like family member 38b 563341 3.1 5.9
-0.9
3.9
-0.8
-1.2
1.5
-0.3
-0.9
2.2
-0.1
-1.4
-1.1
1.6
0.8
1.5
0.2



-0.6
0.9
0.5

16 rnf11a ring finger protein 11a 393996 3.0 5.8
2.2
1.6
3.4
1.5
2.2
0.4
3.0
1.5
1.1
0.7
-0.8
2.1
1.1
0.5
0.9
0.7
-0.3
1.6
-0.2
-0.6
5.2
1.1
-0.0
1.3
0.4
17 slc43a2a solute carrier family 43 member 2a 393221 3.0 5.7
0.2
0.0
3.1
1.0
3.5
0.7
1.7
-0.2
2.5
-0.6
2.3
2.1
1.6
-1.3
4.3
1.2
2.7
0.1
1.6
-1.7
1.8
0.3
1.3
0.8
1.1
1.7
0.1
3.6
0.5
0.2
-0.8
2.7
0.2
2.3
-1.0
0.3
-0.9
0.2
-0.1

18 zgc:92606 zgc:92606 100000242 3.0 5.7
-0.1
-0.5
3.5
2.0
0.8
0.6
1.8
1.6
1.3
1.0
2.5
0.1
0.1
-0.2
1.6
1.1
1.3
0.9
0.4
-0.4
1.3
0.5
3.6
1.7
1.4
0.7
1.4
0.5
0.8
0.1
3.9
1.0
0.4
0.3
5.0
2.8
1.8
1.0
0.3
-0.7
1.3
0.2
-0.6
19 znf395a zinc finger protein 395a 571403 3.0 5.7
-0.0
-0.6
1.6
1.1
2.1
1.5
2.0
0.5
1.0
0.1
0.3
-0.8
1.6
0.8
2.2
0.5
-0.0
-0.5
3.2
-0.4
0.9
-0.1
3.0
0.6
0.1
0.1
1.3
0.4
1.3
0.4
0.6
-0.7
1.8
0.5
1.3
0.7
0.2
0.2
0.5
0.2
1.4
1.4

20 fbxo32 F-box protein 32 393891 3.0 5.7
0.2
-1.5
4.0
2.1
1.3
-0.5
1.0
0.2
2.2
0.6
0.9
0.4
3.2
2.3
3.6
2.7
-0.4
-0.9
2.6
1.8
-0.5
-1.2
3.7
1.5
2.1
0.7
2.4
0.9
2.0
1.8
1.0
-0.8
2.1
1.3
1.1
0.9
0.5
-0.3
3.0
1.2
2.0
1.5
0.5
21 calcoco1a calcium binding and coiled-coil domain 1a 334971 3.0 5.7
0.1
-2.2
3.4
2.9
1.2
-0.4
0.7
0.9
0.9
1.1
3.5
0.7
-0.2
-0.1
3.9



1.3
0.4
3.5
0.6
-0.1
0.7

22 nt5dc2 5'-nucleotidase domain containing 2 556186 3.0 5.7
0.4
1.2
1.1
0.1
-0.7
-0.3
-0.5
0.6
0.8
1.0
-0.7
-1.1
-0.0
0.6
1.7
0.4
-2.1
-0.1
-1.4
0.6
-0.4

23 arrdc3a arrestin domain containing 3a 566685 3.0 5.7
2.1
1.1
2.2
1.6
2.0
1.6
2.5
1.6
3.8
2.5
2.5
1.1
1.5
0.2
5.9
5.0
2.6
0.9
-0.2
-0.4
1.4
-0.1
5.5
3.1
4.6
3.4
3.5
1.9
1.9
0.5
2.9
2.0
3.0
2.1
0.3
0.0
2.8
1.4
2.1
1.5
4.4
2.8
2.9
1.9
24 foxo4 forkhead box O4 563719 2.9 5.6
-1.5
3.7
-0.2
2.0
1.3
1.0
0.5
1.9
-0.3
-0.3
-0.1
2.6
2.0
4.8
1.3
0.8
0.6
2.7
0.8
-0.7
1.6

25 tp53inp1 tumor protein p53 inducible nuclear protein 1 568021 2.9 5.5
-0.5
-0.7
2.0
-0.1
1.1
0.1
4.5
0.1
8.6
-0.5
2.5
2.4
3.2
0.9
3.5
-0.7
5.8
0.7
2.2
0.7
3.6
0.5
2.4
-0.6
2.7
0.8
0.7
-0.2
3.2
-0.6
2.0
1.0
2.3
-0.8
1.9
-1.6
2.1
0.3
1.8
0.3
0.2
-1.3

26 irs2a insulin receptor substrate 2a 393285 2.8 5.4
1.6
1.2
3.4
2.5
1.3
0.2
0.4
-0.0
1.2
-1.1
1.9
-0.8
1.3
0.8
1.1
-0.5
3.4
-0.7
0.4
-0.7
1.7
0.9
1.6
-0.2
1.6
0.5
2.8
2.8
-0.4
-0.9
2.8
-0.9
1.3
-0.3
0.2
-1.3
1.0
-1.3
0.8
-0.6
0.6
-0.4
-0.2
27 hbp1 HMG-box transcription factor 1 554137 2.8 5.3
-0.2
2.7
-1.2
2.1
2.8
1.2
1.6
4.1
1.2
0.3
-0.1
3.5
3.5
2.1
0.5
2.3
3.0
1.3
1.6
-0.1
2.8

28 pik3ip1 phosphoinositide-3-kinase interacting protein 1 386643 2.8 5.3
0.4
2.4
1.6
3.3
6.6
0.8
3.0
5.7
-0.9
-0.3
-1.2
4.9
-0.3
3.9
0.8
0.5
6.0
1.2
1.2
0.5
2.7
0.0
29 mkrn1 makorin, ring finger protein, 1 170782 2.8 5.3
-0.1
-0.6
4.4
2.1
0.2
-0.3
2.2
-0.1
1.4
1.1
2.3
0.6
0.8
0.1
2.3
1.4
1.4
0.0
1.7
0.3
0.3
0.0
3.6
3.0
0.1
-1.2
-0.1
-0.2
0.8
-0.6
1.9
-0.8
0.3
0.1
3.6
-0.1
1.0
0.8
0.9
-1.1
1.6
-0.2
0.0
30 tob1b transducer of ERBB2, 1b 406245 2.8 5.3
-0.8
-0.8
2.3
1.7
2.0
-0.1
1.9
0.3
4.9
0.6
1.8
1.6
2.1
-0.6
2.9
2.2
3.3
2.2
0.3
-0.2
4.2
2.4
1.1
0.3
1.4
1.4
0.9
-0.3
0.6
0.0
2.7
1.6
2.9
-2.1
0.4
0.3
3.6
1.6
0.8
0.7
2.9
0.4

31 klf9 Kruppel-like factor 9 565869 2.7 5.2
-0.2
0.2
-0.9
1.7
3.8
1.7
-1.0
2.5
1.4
-0.9
0.9
2.4
2.6
-0.1
1.9
0.3
3.9
0.3
-0.5
1.4
1.9

32 trim63a tripartite motif containing 63a 415223 2.7 5.1
1.1
0.3
4.5
3.7
1.7
0.9
1.1
1.0
2.2
0.5
-1.2
-1.5
1.0
0.2
0.7
-0.4
0.3
-0.9
1.2
-0.1
-0.1
-0.6
0.6
-0.8
1.1
-2.6
1.3
-0.3
0.8
-1.0
-2.4
0.9
0.3
0.9
-0.5
1.5
-0.7
1.7
0.5
2.3
33 znf395b zinc finger protein 395b 566703 2.7 5.1
-0.0
-0.6
1.6
1.1
2.1
1.5
2.0
0.5
1.0
0.1
0.3
-0.8
1.6
0.8
2.2
0.5
-0.0
-0.5
3.2
-0.4
0.9
-0.1
3.0
0.6
0.1
0.1
1.3
0.4
1.3
0.4
0.6
-0.7
1.8
0.5
1.3
0.7
0.2
0.2
0.5
0.2
1.4
1.4

34 irs2b insulin receptor substrate 2b 572001 2.7 5.0
1.6
1.2
3.4
2.5
1.3
0.2
0.4
-0.0
1.2
-1.1
1.9
-0.8
1.3
0.8
1.1
-0.5
3.4
-0.7
0.4
-0.7
1.7
0.9
1.6
-0.2
1.6
0.5
2.8
2.8
-0.4
-0.9
2.8
-0.9
1.3
-0.3
0.2
-1.3
1.0
-1.3
0.8
-0.6
0.6
-0.4
-0.2
35 arrdc3b arrestin domain containing 3b 447866 2.7 5.0
2.1
1.1
2.2
1.6
2.0
1.6
2.5
1.6
3.8
2.5
2.5
1.1
1.5
0.2
5.9
5.0
2.6
0.9
-0.2
-0.4
1.4
-0.1
5.5
3.1
4.6
3.4
3.5
1.9
1.9
0.5
2.9
2.0
3.0
2.1
0.3
0.0
2.8
1.4
2.1
1.5
4.4
2.8
2.9
1.9
36 zgc:77849 zgc:77849 322387 2.6 5.0
2.1
0.7
4.6
1.8
-1.0
-1.0
-0.5
-0.1
3.4
1.0
1.1
1.9
1.1
0.1
1.0
-1.4
1.1
-0.4
0.7
-0.1
0.2
4.3
0.7
2.2
1.5
0.7
-0.8

37 ctdsp2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 321465 2.6 5.0
0.4
-1.2
2.4
0.2
0.8
0.1
1.3
0.9
1.2
-0.0
1.3
0.6
0.6
0.1
3.7
0.9
0.5
-0.5
0.5
-0.7
1.5
0.3
4.0
2.6
2.4
1.4
3.0
1.4
0.7
-0.9
3.7
-0.6
1.5
1.3
0.4
0.3
2.9
1.9
-0.4
-0.4
1.5
0.8
0.7
38 txnipa thioredoxin interacting protein a 368359 2.6 4.9
2.1
1.1
2.2
1.6
2.0
1.6
2.5
1.6
3.8
2.5
2.5
1.1
1.5
0.2
5.9
5.0
2.6
0.9
-0.2
-0.4
1.4
-0.1
5.5
3.1
4.6
3.4
3.5
1.9
1.9
0.5
2.9
2.0
3.0
2.1
0.3
0.0
2.8
1.4
2.1
1.5
4.4
2.8
2.9
1.9
39 fam13b family with sequence similarity 13 member B 568603 2.6 4.9
-0.0
3.7
2.0
1.4
0.8
0.1
1.9
-0.4
2.2
-0.1
1.2
-0.4
-0.9
-1.6
0.9
0.0
-0.7
0.8
0.8
1.5
0.0

40 trim63b tripartite motif containing 63b 394070 2.6 4.9
1.1
0.3
4.5
3.7
1.7
0.9
1.1
1.0
2.2
0.5
-1.2
-1.5
1.0
0.2
0.7
-0.4
0.3
-0.9
1.2
-0.1
-0.1
-0.6
0.6
-0.8
1.1
-2.6
1.3
-0.3
0.8
-1.0
-2.4
0.9
0.3
0.9
-0.5
1.5
-0.7
1.7
0.5
2.3
41 ucp3 uncoupling protein 3 794081 2.5 4.8
1.6
0.3
1.3
1.2
0.6
-0.7
1.5
0.3
-0.6
-0.3
-0.4
2.0
0.0
1.2
0.5
0.3
-0.2
0.4
-0.4
0.4
-0.2
-0.1
1.0
-0.4
-0.3
-2.1
0.6
0.2
2.5
0.4
0.0
-1.3
1.2
-0.1
1.0
0.9

42 cdkn1d cyclin-dependent kinase inhibitor 1D 100151464 2.5 4.8
-1.4
1.5
-0.4









1.1
-1.9
-0.5







43 pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 557176 2.5 4.7
2.8
0.7
2.1
0.2
1.7
0.5
3.4
3.1
4.3
1.1
1.9
0.1
4.0
2.0
3.4
1.2
1.5
1.2
4.1
2.2
1.0
-0.6
1.5
1.0
0.1
-1.4
2.5
0.3
2.2
1.9
1.9
0.4
2.2
0.4
1.7
1.1
1.5
0.2
3.0
1.7
1.9
1.8
-0.7
44 ghrb growth hormone receptor b 560202 2.5 4.7






















45 si:ch211-117k10.3 si:ch211-117k10.3 556200 2.5 4.7
-1.2
0.9
-0.9









0.2
-0.6
0.8







46 klhl24b kelch-like family member 24b 393412 2.4 4.6
-0.5
-1.9
3.2
2.7
0.3
-0.7
3.4
3.3
1.2
3.3
3.9
0.7
1.2
-1.7
2.7
1.5
2.0
1.5
1.0
2.6
2.1
0.6
0.8
1.0

47 serpina10a serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a 565064 2.4 4.6






















48 nbr1a NBR1 autophagy cargo receptor a 337168 2.4 4.6
1.6
-0.3
3.5
0.5
1.5
-0.0
0.3
0.9
1.1
0.7
3.0
0.0
-1.1
0.4
1.5
0.2
0.4
-0.5
2.5
-0.0
1.0
1.8
-0.6
0.6

49 akr1b1.2 aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2 553452 2.4 4.6
-0.1
-0.3
2.2
0.7
1.3
0.4
1.3
0.9
1.3
0.8
0.7
0.4
0.6
0.6
1.3
0.9
1.2
1.0
0.8
0.4
1.5
1.4
1.5
1.5
0.7
0.2
1.0
0.7
0.5
0.2
0.3
-0.1
0.7
0.3
0.9
0.8
0.4
-0.4
0.5
-0.2
1.1
-0.1
1.1
0.3
50 trim3b tripartite motif containing 3b 555391 2.4 4.6
-0.4
-0.5
3.7
0.4
1.6
-0.1
-1.5
1.6
0.5
2.6
-1.4
0.3
-0.6
0.5
0.2
0.1
-2.7
-0.1
-0.9
0.7
0.2
0.8
-0.4
3.1
0.2
1.2
0.3
-1.1
0.2
-0.6
1.1
-1.0
-1.2
1.1
-0.5
The preparation time of this page was 1.0 [sec].