Orthologous genes in OrthoFinder**

Species Gene Description
 dre-r.3   pfkfb1   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 dre-u.3   pfkfb1   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 dre-m.5   pfkfb1   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 dre-u.3   pfkfb2b   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b 
 dre-u.3   pfkfb4a   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a 
 hsa-u.4   PFKFB2   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 hsa-u.4   PFKFB3   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 mmu-u.4   Pfkfb2   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mmu-u.4   Pfkfb1   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 mmu-u.4   Pfkfb4   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 rno-u.3   Pfkfb3   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 rno-u.3   Pfkfb2   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 gga-u.3   PFKFB4   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 gga-u.3   PFKFB1   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 
 gga-u.3   PFKFB2   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mcc-u.3   PFKFB4   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 mcc-u.3   PFKFB2   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 mcc-u.3   PFKFB3   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 cfa-u.3   PFKFB4   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 
 cfa-u.3   PFKFB2   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 
 cfa-u.3   PFKFB3   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 
 dme-u.3   Pfrx   6-phosphofructo-2-kinase 
 cel-u.3   pfkb-1.1   6-phosphofructo-2-kinase 
 cel-u.3   pfkb-1.2   Fructose-2,6-bisphosphatase 
 sce-u.3   YLR345W   bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase 
 sce-u.3   FBP26   fructose-2,6-bisphosphatase 

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Top 50 coexpressed genes to pfkfb1 (dre-r.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre3008   Ribosome biogenesis in eukaryotes  4 75 4.46
 dre513   Various types of N-glycan biosynthesis  1 50 -
 dre280   Valine, leucine and isoleucine degradation  1 59 -
 dre10   Glycolysis / Gluconeogenesis  1 81 -
 dre4020   Calcium signaling pathway  3 377 -

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dre:pfkfb1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-r.3
for
pfkfb1
dre-u.3
for
pfkfb1
dre-m.5
for
pfkfb1
dre-u.3
for
pfkfb2b
dre-u.3
for
pfkfb4a
hsa-u.4
for
PFKFB2
hsa-u.4
for
PFKFB3
mmu-u.4
for
Pfkfb2
mmu-u.4
for
Pfkfb1
mmu-u.4
for
Pfkfb4
rno-u.3
for
Pfkfb3
rno-u.3
for
Pfkfb2
gga-u.3
for
PFKFB4
gga-u.3
for
PFKFB1
gga-u.3
for
PFKFB2
mcc-u.3
for
PFKFB4
mcc-u.3
for
PFKFB2
mcc-u.3
for
PFKFB3
cfa-u.3
for
PFKFB4
cfa-u.3
for
PFKFB2
cfa-u.3
for
PFKFB3
dme-u.3
for
Pfrx
cel-u.3
for
pfkb-1.1
cel-u.3
for
pfkb-1.2
sce-u.3
for
YLR345W
sce-u.3
for
FBP26
1 utp4 UTP4 small subunit processome component 406571 2.7 4.1
 1.1
 -0.2
 0.7
 -0.8
 0.5
 -0.6
 -0.4
 -0.6
 0.6
 -0.4
 -1.0
 -1.1
 0.1
 -1.5
 -0.6
 0.5
 0.0
 -0.1
 -0.3
 -0.1
 0.8
 0.8
 0.8
 -0.5
2 itih6 inter-alpha-trypsin inhibitor heavy chain family member 6 565328 2.4 4.6
0.8
 -0.0
 -1.0
 -0.5




0.4
 0.0
 1.7










3 crls1 cardiolipin synthase 1 405867 2.4 3.5
 0.9
 0.3
 1.0
 0.4
 0.0
 -0.6
 1.0
 -1.9
 0.3
 -1.2
 -2.0
 -0.7
 0.4
 -1.1
 -0.7
 -0.2
 -0.5
 -1.2
 -1.3
 0.5
 2.0
 2.2
 -0.3
 1.4
4 metap1 methionyl aminopeptidase 1 503783 2.4 3.1
 0.6
 0.3
 0.1
 -1.3
 -0.7
 0.9
 1.7
 0.3
 0.6
 0.4
 0.0
 -0.7
 -1.1
 0.0
 -2.0
 -1.5
 0.2
 1.2
 -0.8
 -0.2

0.1
 -0.1
5 msrb1a methionine sulfoxide reductase B1a 352916 2.3 4.0
 1.4
 -0.1
-1.1
 1.7
0.9
 -0.7
 0.6
 -0.8
 0.8
 1.6
 0.7
 -1.0
 -0.3
 0.7
 0.4
 2.9
 1.3
 -0.2
 0.8
 1.7
 -1.1




6 coq8aa coenzyme Q8A, genome duplicate a 437001 2.3 3.6
 1.1
 1.3
0.7
 2.6
1.3
 1.0
0.7
 0.8
0.7
 1.4
-0.7
 1.0
0.4
 1.8
-0.9
 0.3
-0.4
 1.0
-0.8
 0.2
 0.9
 -0.5
 1.3
-1.2
 1.3
-1.2
 -0.8
-0.9
 0.9
0.6
 1.1
-0.5
 0.7
0.7
 0.8
 0.8
 3.1
 -1.4
 -1.0
7 rrp12 ribosomal RNA processing 12 homolog 563195 2.2 4.2
0.0
 -0.3
 1.5
 2.5
 0.8
 -0.6
 1.9
 0.5
 -0.3
 -0.5
 -0.0
 -0.8
 2.3
 2.4
 1.4
 1.6
 1.3
 2.3
 1.6
 -2.4
 -0.7
 -1.0
 -1.1
8 sdad1 SDA1 domain containing 1 286746 2.2 4.1
 1.6
 -0.8
 0.3
 -0.5
 -2.3
 -0.3
 -0.6
 0.2
 0.5
 -0.7
 -1.2
 -1.5
 -0.6
 -1.4
 -0.3
 -0.9


0.5
 -1.3
 -1.0
 0.1
 0.6
9 znhit6 zinc finger HIT-type containing 6 100332549 2.2 4.1
-0.3
 1.4
 1.0
 -0.2
 -1.8
 -0.4
 -1.7
 -1.0
 -0.8
 1.0
 -0.3
 -1.4
 -1.9
 0.0
 -0.6
 -0.8
 -0.6
 -0.9
 -0.2
 -0.6
 0.4
 -0.2
 -1.6
10 tyw3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) 436884 2.2 2.0
 -0.3
 -1.0
 0.9
 -0.3
 -2.1
 -0.1
 -0.6
 -0.2
 -0.9
 -0.5
 0.1
 -0.4
 0.3
 -0.4
 -1.0
 -1.6
 -0.1
 0.1
 -1.3


1.3
 0.2
11 polr1a RNA polymerase I subunit A 327078 2.1 2.6
 0.3
 0.9
 0.5
 1.0
 -0.5
 0.2
 0.6
 0.6
 -0.6
 -0.9
 -1.1
 -0.7
 1.5
 -0.3
 0.3
 -0.8
 0.4
 1.4
 -0.7
 0.7
 -1.7
 -1.1
 0.0
 -0.0
12 stim2a tromal interaction molecule 2a 100334881 2.0 3.8
1.1
0.4
 0.4
0.4
 1.7
-0.6
 0.5
-0.2
 -0.1
-1.2
 0.2
-1.1
 1.2
-0.3
 0.1
-0.2
 -0.2
-0.4
 -1.1
-2.5
 0.2
-0.3
 0.9
-0.5
 0.7
-0.2
 -1.1
-2.0
 1.6
-0.4
 2.7
-0.5
 0.4
-1.4
 1.7
1.5
 -0.3
 1.8
 2.1

13 ngrn neugrin, neurite outgrowth associated 569275 2.0 3.8
-0.8
 1.7
 -0.1
 -0.3
 0.1
 -0.2
 -0.2
 -0.3
 2.2


-0.2
 0.8
 0.9
 -0.7
 0.2
 0.3
 -0.2



14 dph2 diphthamide biosynthesis 2 562538 2.0 3.8
0.4
 0.3
 1.0
 -0.6
 -0.3
 -0.9
 1.5
 0.6
 1.1
 -1.3
 0.2
 -0.4
 -0.7
 -0.9
 -0.4
 0.4
 0.4
 -0.4
 1.1
 -0.8
 1.3
 -1.3
 -1.2
15 b4galnt3b beta-1,4-N-acetyl-galactosaminyl transferase 3b 553524 2.0 3.7
1.2
 2.1
 0.7
 0.4
 0.4
 0.2
 0.8

-0.3
 -0.4
 -0.5
 -1.4
 0.3
 -0.7
 0.1
 -0.1
 0.9




16 tpcn2 two pore segment channel 2 777614 1.9 3.7
-0.5
 1.5
 1.9
 1.2




0.0
 0.2
 -0.5
 2.7
 -1.6
 -1.6
 2.8
 1.6
 -0.7




17 ivd isovaleryl-CoA dehydrogenase 368775 1.9 3.2
 1.1
 2.3
 0.9
 1.0
 -0.7
 1.0
 1.7
 -0.3
 -0.8
 0.3
 0.3
 -0.4
 0.1
 1.7
 0.7
 3.0
 2.8
 2.0
 0.3
 0.5
 0.3
 0.1

18 fbxo32 F-box protein 32 393891 1.9 2.9
 0.8
 0.4
-0.4
 2.1
1.7
 0.9
-0.5
 0.7
-1.4
 1.1
0.2
 -0.3
-0.6
 0.7
0.6
 2.9
-0.5
 0.7
0.6
 1.1
0.6
 1.0
0.7
 -0.5
-1.7
 -0.9
-2.5
 0.6
-0.5
 0.2
-0.3
 0.9
0.2
 -0.2
-0.3
 1.7
0.7
 0.6
 1.0
 -0.5

19 p2rx4a purinergic receptor P2X, ligand-gated ion channel, 4a 259258 1.9 2.6
 0.6
 0.9
 -0.7
 -0.9
 -0.2
 1.5
 -1.3
 0.5
 -0.4
 -0.2
 2.2
 1.8
 0.6
 -2.2
 -2.0
 0.1
 -0.5
 0.3
 -0.6




20 calcoco1b calcium binding and coiled-coil domain 1b 386968 1.9 2.4
 0.4
 0.3
-0.3
 0.3
-0.6
 0.0
 -0.0
 1.1
 -0.2
 -0.9
 1.1
 0.7


-0.2
 -0.7
 -0.2
 1.4
 0.9
 1.1




21 fhip2b FHF complex subunit HOOK interacting protein 2B 777718 1.9 3.5























22 asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 664764 1.9 3.5
0.7
 0.8
 1.2
 -0.9
 1.0
 -0.1
 0.4
 -0.6
 0.5
 0.5
 -0.3
 0.9
 0.1
 2.1
 -1.1
 1.4
 0.3
 -1.4




23 mical2b microtubule associated monooxygenase, calponin and LIM domain containing 2b 569564 1.9 3.6
1.9
0.7
 2.5
-1.0
 0.8
 -0.3
 1.1
 -0.1
 0.8
 2.2
 0.4
 2.3
 -0.1
 -0.9
 -0.1
 -0.0
 -1.6
 -0.3
 -0.9
 0.8
 -0.2



24 acss1 acyl-CoA synthetase short chain family member 1 541435 1.9 1.9
 -0.0
 2.3
0.9
 2.6
0.1
 3.4
0.3
 -0.1
-1.1
 1.4
0.6
 1.2
-1.1
 1.8
1.3
 -0.0
-1.0
 1.3
-0.3
 3.1
0.4
 1.2
0.4
 3.2
0.8
 0.9
-1.5
 0.6
-0.2
 0.4
-0.1
 2.5
0.6
 0.9
-0.0
 2.0
-0.7
 4.5
 4.4
 2.7
 -0.5
-0.6
 -0.8
-0.8
25 ston2 stonin 2 619262 1.9 2.5
 0.5
 -0.1
 0.5
 1.6
 0.3
 -0.4
 -0.3
 1.9
 -0.5
 0.5
 1.2
 1.2
 -0.5
 1.3
 2.6
 1.6
 0.4
 1.1
 -1.0
-1.6
 -0.3

26 tsr3 TSR3 ribosome maturation factor 436643 1.9 1.9
 -0.1
 -1.4
 1.2
 -0.7
 -0.9
 -1.1
 -0.2
 0.3
 -0.3
 -0.1
 -0.2
 -0.1
 -0.5
 -0.9
 -1.1
 -1.7
 -1.1
 -0.7
 0.6
 -1.5
 -0.4
 -1.1
 0.0
 -0.5
27 ognb osteoglycin, paralog b 100170815 1.9 3.5
1.5
 0.4
 -0.7
 -1.7
 0.1
 -0.6
 -0.5
 -0.6
 -0.2
 0.4
 -0.4
 -0.3
 -0.3
 -0.6
 2.0
 -0.4
 -0.2
 -1.5




28 pno1 partner of NOB1 homolog 393520 1.9 2.6
 0.6
 -0.9
 0.5
 0.3
 0.1
 -0.5
 -0.5
 -0.3
 0.2
 -2.0
 -1.2
 0.2
 -1.0
 -0.9
 1.6
 1.5
 -0.7
 -1.5
 0.6
 1.8
 3.5
 -0.0
 0.1
 -0.6
29 klhl38b kelch-like family member 38b 563341 1.9 3.5
1.0
 1.1
 0.7
 -0.5
 0.8
 0.8
 0.1
 -0.2
 -0.4
 0.4
 -0.1
 -0.8


1.2
 -0.0
 -1.0




30 dnttip2 deoxynucleotidyltransferase, terminal, interacting protein 2 564961 1.8 2.5
 0.5
 0.1
 0.8
 -0.3
 0.5
 -0.7
 -0.7
 -1.1
 -0.4
 -0.9
 -0.5
 -0.7
 -0.2
 -0.4
 -1.0
 2.4
 -1.1
 -1.7
 -0.3
 -0.7
 -1.0
 0.6
 0.5
 -0.4
31 mtrf1 mitochondrial translational release factor 1 503530 1.8 3.5
0.2
 -1.5
 -0.2
 -1.0
 0.0
 4.2
 -0.7
 0.5
 0.3
 -1.6
 1.3
 -0.9
 0.2
 -0.9
 -0.4
 -0.4
 0.8
 -1.5




32 cep63 centrosomal protein 63 393574 1.8 3.4
-0.5
 1.6
 0.5
 -0.4
 0.6
 0.3
 0.1
 -0.9
 0.2
 -0.4
 -0.7
 0.7
 -0.8
 1.3
 0.1
 -1.5
 -0.9
 0.3




33 rbm28 RNA binding motif protein 28 393291 1.8 2.7
 0.8
 0.1
 0.5
 0.6
 -0.2
 -1.2
 -0.4
 0.8
 -0.4
 -1.8


-0.7
 0.2
 -1.5
 -0.9
 -0.6
 1.0
 0.9
 -0.4
 -0.4
 1.0
 -0.1
34 ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains 541415 1.8 2.2
 0.2
 0.6
 1.2
 1.1
 -0.7
 -0.9
 0.5
 -0.4
 0.5
 -1.5
 -1.1
 1.4
 -0.1
 -0.2
 1.1
 0.5
 2.1
 -0.2
 -0.9
 2.0
 -0.1
 1.2

35 selenoo1 selenoprotein O1 558648 1.8 2.8
 0.8
 1.1
0.7
 1.5
-0.9
 -1.2
 0.9
 0.0
 1.4
 0.4
 -0.7
 0.5
 -1.9
-2.8
 0.8
0.5
 -0.3
-0.5
 -0.5
 -1.6
 -1.0
 0.6
 0.6
 1.5


2.1
 -0.4
36 metap1d methionyl aminopeptidase type 1D (mitochondrial) 554090 1.8 3.4
-0.8
 1.1
 -0.2
 -1.2
 3.0
 2.5
 -0.4
 -0.0
 -1.2
 -0.6
 0.1
 2.0
 -0.4
 -0.7
 0.9
 -0.2
 -0.6
 0.3
 -1.4



37 rdh14a retinol dehydrogenase 14a 450010 1.8 3.4
1.5
0.5
 3.5
1.4
 2.0
1.2
 2.1
0.7
 2.3
0.4
 1.0
0.6
 2.4
1.6
 -0.4
-0.7
 0.5
0.0
 0.6
0.3
 2.5
0.1
 1.0
0.4
 -0.0
-0.1
 0.5
0.5
 1.3
1.0
 1.5
1.1
 2.6
1.5
 1.3
0.8
 1.0
0.5
 4.0
2.1
 3.2
2.8
 -0.7
 -0.6
38 hnf4a hepatocyte nuclear factor 4, alpha 322358 1.8 2.6
 0.7
 0.0
-0.6
 0.6
-1.6
 -0.2
-0.7
 -0.2
-0.8
 2.0
 0.4
 -0.3
 -0.1
-0.9
 0.1
-0.5
 -0.3
-0.5
 1.4
0.7
 0.2
-0.1
 0.4
-0.7
 -0.1
-0.8
 0.3
-0.7
 0.4
-0.9
 0.3
0.1
 -0.4
-1.6
 1.9
 2.5
0.3
 -0.8
-1.2

39 si:dkey-238d18.4 si:dkey-238d18.4 796120 1.8 3.4























40 badb BCL2 associated agonist of cell death b 58100 1.8 3.0
 1.1
 -0.4
-1.2
 3.6
3.2
 -1.1
 -1.2
 0.4
 -1.9
 2.0
 -1.8
 -1.6


-0.6
 0.3
 0.0
 1.7
 -0.9
 -0.3




41 mfsd4aa major facilitator superfamily domain containing 4Aa 393503 1.8 2.8
 0.8
 0.7
 0.5
 0.1
 0.2
 1.4
 -1.1
 -0.7
 0.2
 -0.3
 -0.2
 -0.6
 1.7
 -1.5
 -0.7
 -0.4
 0.1
 0.4
 -2.8




42 tma16 translation machinery associated 16 homolog 553647 1.8 2.4
 0.5
 0.3
 -0.2
 -2.0
 -1.0
 -1.8
 -0.3
 -1.3
 0.6
 -1.4
 -0.8
 0.3
 -1.1
 0.2
 0.8
 0.2
 -1.1
 -1.0
 -0.4
 0.6

0.6
 0.8
43 slx9 SLX9 ribosome biogenesis factor 797099 1.8 2.5
 0.6
 -0.4
 1.2
 -0.6
 0.7
 -1.1
 -1.9
 0.3
 -0.1
 -1.4
 0.8
 0.2
 -1.9
 0.0
 0.3
 -0.4
 0.1
 0.4
 0.2
 -0.2



44 sec16b SEC16 homolog B, endoplasmic reticulum export factor 553356 1.8 3.3
0.1
-0.8
 0.5
-0.0
 1.4
 1.2
 1.5
1.4
 1.9
-0.6
 0.4
0.2
 -0.8
-1.6
 1.6
-0.3
 -0.6
-1.4
 0.4
-0.6
 0.3
0.3
 -0.9
-1.1
 -0.3
-0.8
 -0.7
-1.0
 1.6
-1.0
 1.5
-0.3
 1.9
-0.5
 -0.9
 0.2
0.2
 -0.4
-2.6
 -1.5
 -0.6
45 aup1 AUP1 lipid droplet regulating VLDL assembly factor 324654 1.8 1.6
 -0.2
 -0.0
 1.1
 -0.4
 -1.3
 -0.7
 -0.8
 -0.0
 -0.4
 -1.4
 -0.8
 1.3
 0.1


-0.5
 -0.6
 -1.0
1.2
 3.9

46 cyp2p7 cytochrome P450, family 2, subfamily P, polypeptide 7 100034406 1.8 3.3
1.9
1.8
 0.8
0.1
 -0.1
 -1.1
 0.8
-0.9
 0.5
0.2
 -0.7
-0.9
 0.4
0.4
 0.4
-1.0
 0.5
-0.2
 2.6
2.4
 1.6
0.5
 -1.2
 1.3
 0.1
 -0.5
 0.1
 -0.7
 0.3
0.3
 1.0
0.7
 1.1
0.5

47 erich1 glutamate rich 1 100002532 1.8 3.3
-0.0
 1.0

-0.5
 -0.4
 -0.4
 0.9
 0.5
 -1.0
 -1.7
 -0.6
 1.0
 0.3
 1.2
 -0.8
 -0.4
 1.5




48 rcl1 RNA terminal phosphate cyclase-like 1 445388 1.7 3.1
 1.1
 -1.8
 -0.1
 -0.3
 1.5
 -1.9
 0.9
 -1.3
 -0.3
 -1.6
 0.7
 -0.2
 0.6
 -1.3
 0.0
 0.8
 1.0
 0.5
 0.2
 -0.6
 -0.4
 1.4
 -0.1
 -0.6
49 rpp30 ribonuclease P/MRP 30 subunit 541352 1.7 3.3
1.1
 -0.8
 -1.5
 -0.9
 -1.8
 0.9
 -0.1
 0.3
 -0.8
 0.6
 -0.6
 -1.0
 0.4
 -2.0
 -1.8
 -0.5
 -0.3
 -0.9
 -0.9
 -0.6
 1.0
 -1.4
 -1.6
50 marchf7 membrane-associated ring finger (C3HC4) 7 100136862 1.7 2.6
 0.7
 -1.0
 1.7
 -0.7
 0.2
 -0.3
 -0.7
 1.8
 2.3
 3.0
 0.3
 0.2
 -0.0
 2.1
 1.1
 -0.4
 0.0
 0.0
 -0.0




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