Orthologous genes in OrthoFinder**

Species Gene Description
 dre-r.3   iars2   isoleucyl-tRNA synthetase 2, mitochondrial 
 dre-u.3   iars2   isoleucyl-tRNA synthetase 2, mitochondrial 
 hsa-u.4   IARS2   isoleucyl-tRNA synthetase 2, mitochondrial 
 mmu-u.4   Iars2   isoleucine-tRNA synthetase 2, mitochondrial 
 rno-u.3   Iars2   isoleucyl-tRNA synthetase 2, mitochondrial 
 gga-u.3   IARS2   isoleucyl-tRNA synthetase 2, mitochondrial 
 mcc-u.3   IARS2   isoleucyl-tRNA synthetase 2, mitochondrial 
 cfa-u.3   IARS2   isoleucyl-tRNA synthetase 2, mitochondrial 
 dme-u.3   IleRS-m   Isoleucyl-tRNA synthetase, mitochondrial 
 cel-u.3   iars-2   Isoleucyl-tRNA synthetase 
 sce-u.3   ISM1   isoleucine--tRNA ligase ISM1 
 spo-u.3   SPAC27E2.06c   putative methionine--tRNA (Met) ligase 

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Top 50 coexpressed genes to iars2 (dre-r.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dre1200   Carbon metabolism  4 134 3.48
 dre640   Propanoate metabolism  3 31 4.22
 dre280   Valine, leucine and isoleucine degradation  3 57 3.43
 dre20   Citrate cycle (TCA cycle)  2 35 2.48
 dre10   Glycolysis / Gluconeogenesis  2 81 -

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dre:iars2 (isoleucyl-tRNA synthetase 2, mitochondrial) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dre-r.3
for
iars2
dre-u.3
for
iars2
hsa-u.4
for
IARS2
mmu-u.4
for
Iars2
rno-u.3
for
Iars2
gga-u.3
for
IARS2
mcc-u.3
for
IARS2
cfa-u.3
for
IARS2
dme-u.3
for
IleRS-m
cel-u.3
for
iars-2
sce-u.3
for
ISM1
spo-u.3
for
SPAC27E2.06c
1 cluha clustered mitochondria (cluA/CLU1) homolog a 562666 3.7 7.1
 2.3
 3.9
 3.7
 3.4
 2.4
 3.3
 3.6
 5.1
 3.4
 -0.1
2 rhot1a ras homolog family member T1a 327143 3.6 6.9
 2.9
-0.1
 2.2
1.3
 0.4
0.4
 1.7
1.0
 3.9
-0.3
 2.0
0.5
 -0.6
 1.7
 0.2
3 hm13 histocompatibility (minor) 13 259190 3.6 6.8
 -1.2
 0.2
 0.8
 1.2
 0.4
 0.4
 -1.6
 0.3
 -1.2
 1.4
4 lrpprc leucine-rich pentatricopeptide repeat containing 557195 3.4 6.6
 7.7
 6.5
4.9
 6.3
 3.2
 7.2


5 mipepa mitochondrial intermediate peptidase a 100005953 3.4 6.5
 5.8
 4.0
 4.9
 4.3
 5.5
 2.7
 3.5
 5.8
 2.6
 0.6
6 trim24 tripartite motif containing 24 442869 3.4 6.4
 -0.1
-1.4
 0.1
-0.3
 -0.9
 1.1
1.1
 1.2
1.0
 -0.3
-0.7
 -0.3
-0.4
 -0.0

7 ascc3 activating signal cointegrator 1 complex subunit 3 100332599 3.3 6.3
 3.0
-0.2
 2.8
-0.3
 3.8
-0.6
 2.0
1.6
 2.3
 1.5
1.4
 1.9
1.2
 2.7
0.9
 0.8
0.4
 0.0
8 ap1b1 adaptor related protein complex 1 subunit beta 1 562166 3.3 6.2
 1.7
1.1
 0.5
0.1
 1.7
1.3
 1.7
0.7
 2.0
1.6
 2.8
1.1
 -0.3
 -0.1
 -0.1
 -0.5
9 dnajc11a DnaJ (Hsp40) homolog, subfamily C, member 11a 322953 3.2 6.2
 1.5
 0.9
 1.4
 4.4
 1.3
 2.0
 0.7
 4.6

10 lars2 leucyl-tRNA synthetase 2, mitochondrial 100126021 3.2 6.2
 2.2
 2.9
 7.5
 5.8
 1.9
 -0.6
 5.6
 5.5
 6.0
 -1.6
11 pa2g4a proliferation-associated 2G4, a 368737 3.2 6.1
 0.5
 0.1
 -0.0
 1.7
 0.8
 0.5
 0.3
 1.3
 0.0
12 xpnpep3 X-prolyl aminopeptidase 3, mitochondrial 573360 3.2 6.0
2.5
 1.0
 2.8
 2.1
 0.8
 0.2
 2.2
 1.4
 -0.2
13 hadhab hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b 793834 3.0 5.8
 4.5
 3.6
 5.5
 3.2
 4.8
 2.5
 1.3
 2.8
1.0
0.0
14 trap1 TNF receptor-associated protein 1 571959 3.0 5.6
 4.3
 5.6
 6.9
 5.4
 3.7
 2.4
 3.2
 6.9

15 sars2 seryl-tRNA synthetase 2, mitochondrial 394154 3.0 5.6
 0.7
4.1
 1.7
 1.2
 0.6
 4.4
 3.5
 4.3
 -1.1
16 pitrm1 pitrilysin metallopeptidase 1 406808 2.9 5.6
 3.2
 5.9
 6.6
 2.5
 4.8
 1.7
 4.2
3.9
17 nsfl1c NSFL1 (p97) cofactor (p47) 492805 2.9 5.6
 -0.1
-0.4
 -0.5
-0.8
 1.3
-1.8
 -0.1
-0.7
 0.5
0.2
 -0.7
-1.0
 0.0
-1.4
-0.2
 -0.6
18 scfd2 sec1 family domain containing 2 792105 2.9 5.5
 0.6
 2.0
 3.3
 1.2
 0.9
 0.3



19 vwa8 von Willebrand factor A domain containing 8 561317 2.8 5.3
 4.1
 6.6
 4.9
 3.8
 3.5
 5.1
 3.1
 3.3

20 abhd18 abhydrolase domain containing 18 503769 2.8 5.2
 -0.5
 0.8
 0.6
 1.1
 2.5
 2.1
 2.0
 -0.6

21 caprin1a cell cycle associated protein 1a 445090 2.7 5.2
 2.4
-0.9
 3.2
1.0
 1.9
0.9
 0.1
-0.0
 2.5
1.2
 2.3
1.4
 -0.5


22 ilf3b interleukin enhancer binding factor 3b 321868 2.7 5.1
 0.0
 1.3
 1.7
 -0.3
 -0.3
 0.3



23 pmpca peptidase, mitochondrial processing subunit alpha 492801 2.6 5.0
 1.7
 4.5
 5.0
 4.5
 2.0
 2.4
 2.9
 3.9
 1.9
 1.0
24 smg5 SMG5 nonsense mediated mRNA decay factor 553261 2.6 5.0
 0.8
 1.3
 0.7
-0.3
 -1.0
 0.8
 0.8
 -2.0


25 tpra translocated promoter region a, nuclear basket protein 571089 2.6 5.0
 5.1
 2.8
 1.1
 2.1
 2.9
 1.1
 1.5
-0.7
-0.7
26 afg3l1 AFG3-like AAA ATPase 1 570430 2.6 4.9
 6.3
1.6
 5.3
5.1
 5.0
4.8
 3.6
3.6
 5.8
3.3
 5.5
0.4
 1.0
0.4
 5.2
4.2
 3.0
2.5
27 zmp:0000000662 zmp:0000000662 100002825 2.6 4.9
 1.4
 2.1
 -0.4
 0.7
-0.8
 1.6
 1.4
0.8

28 timm44 translocase of inner mitochondrial membrane 44 homolog (yeast) 541380 2.6 4.9
 -0.7
 3.3
 2.8
 4.0
 2.7
 0.8
 2.6
 4.3
 1.4
 -0.4
29 pccb propionyl-CoA carboxylase subunit beta 405861 2.5 4.8
 3.9
 3.1
 3.0
 3.7
 2.4
 1.1
-0.4

30 cttn cortactin 445561 2.5 4.8
 1.2
 2.2
 1.2
 -0.2
 -0.1
 2.6



31 abcb7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 566515 2.5 4.8
 3.9
 2.2
 2.7
 2.5
 3.2
 2.5
 0.6
1.9
 -0.8
32 exd3 exonuclease 3'-5' domain containing 3 100538036 2.5 4.8


1.4
 -1.3
 0.8
 2.6
 2.0
0.2

33 fastk Fas-activated serine/threonine kinase 564534 2.5 4.7
 1.1
 2.0
 1.5
 -0.6
 0.4
 0.4



34 ccdc47 coiled-coil domain containing 47 447812 2.5 4.7
 4.6
 1.9
 2.3
 2.1
 4.4
 1.3
 0.6
 2.1

35 endog endonuclease G 100002293 2.5 4.6
 1.4
 2.0
 1.1
 1.2
 1.3
 0.3
 3.2
 1.7
 2.2
 -0.4
36 atad1b ATPase family AAA domain containing 1b 368412 2.4 4.6
 2.8
 -0.0
 1.6
 3.3
 4.9
 2.3
 0.2
-0.3
 3.4
 1.0
37 acot7 acyl-CoA thioesterase 7 447878 2.4 4.6
 0.0
 -1.3
 -0.4
 0.0
 1.9
 -0.2



38 ipo9 importin 9 406860 2.4 4.6
 5.0
 3.2
 2.3
 2.3
 0.9
 0.7
 0.7
1.8
 0.2
39 dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 324201 2.4 4.6
 6.9
 5.7
 2.1
 3.5
 4.2
 3.9
 1.1
 2.2
 0.5
 1.2
40 scrib scribble planar cell polarity protein 368473 2.4 4.5
 1.7
 0.7
 0.5
 -1.1
0.7
 -1.2


41 abhd11 abhydrolase domain containing 11 446169 2.4 4.5
 -0.4
 1.7
 2.7
 1.3
 0.2
 0.0
 0.3
-0.1
 2.2
 0.1
 0.7
42 mccc1 methylcrotonyl-CoA carboxylase subunit 777632 2.4 4.5
 3.2
 2.8
 4.2
 3.5
 4.2
 1.8
 3.2
 4.6
0.6
43 idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta 415247 2.4 4.5
 3.7
-0.3
 3.5
3.2
 2.9
1.5
 4.0
 3.0
0.4
 1.5
0.8
 1.4
-0.0
 1.7
0.8
 0.4
 0.4
-0.4
44 synrg synergin, gamma 555257 2.4 4.5
 -0.6
 1.0
 0.1
 1.4
 0.7
 0.7
-0.7

45 med24 mediator complex subunit 24 323621 2.4 4.5
 1.2
 0.8
 2.3
 2.0
 1.3
 2.3
 1.3


46 exoc4 exocyst complex component 4 559866 2.4 4.5
2.1
 2.8
 1.0
 1.3
 -0.7
 0.9
 2.3
 1.8
47 acss2 acyl-CoA synthetase short chain family member 2 436914 2.4 4.5
 3.2
0.0
 2.4
2.4
 1.3
0.6
 0.7
0.1
 2.6
-1.1
 2.7
-0.9
 0.5
 -1.0
 -0.4
-1.1
 0.2
-0.1
48 gfm1 G elongation factor, mitochondrial 1 561840 2.4 4.5
 5.2
 5.4
 5.0
 4.4
 5.6
 2.6
 4.9
 3.1
 6.6
 -0.6
49 ripor1 RHO family interacting cell polarization regulator 1 566573 2.3 4.4
 -0.2
-1.3
 1.9
-0.4
 0.0
-0.3
 0.8
-0.5
 0.1
-0.4
 0.5
-0.7
-0.1

50 fam135a family with sequence similarity 135 member A 566435
0.1
-0.6
 -0.2
-0.2
 -1.2
-1.3
 0.6
-1.4
 0.3
-0.9
 2.5
 -0.0
 2.8

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