Orthologous genes in OrthoFinder**

Species Gene Description
 rno-u.3   Isl2   ISL LIM homeobox 2 
 rno-r.3   Isl2   ISL LIM homeobox 2 
 rno-m.5   Isl2   ISL LIM homeobox 2 
 rno-u.3   Lmo1   LIM domain only 1 
 rno-u.3   Isl1   ISL LIM homeobox 1 
 mmu-u.4   Isl2   insulin related protein 2 (islet 2) 
 mmu-u.4   Isl1   ISL1 transcription factor, LIM/homeodomain 
 hsa-u.4   ISL2   ISL LIM homeobox 2 
 hsa-u.4   ISL1   ISL LIM homeobox 1 
 gga-u.3   ISL2   ISL LIM homeobox 2 
 gga-u.3   ISL1   ISL LIM homeobox 1 
 dre-u.3   isl2b   ISL LIM homeobox 2b 
 dre-u.3   isl2a   ISL LIM homeobox 2a 
 dme-u.3   tup   tailup 
 cel-u.3   mec-3   Mechanosensory protein 3 
 cel-u.3   lim-7   LIM/homeobox protein lim-7 

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Top 50 coexpressed genes to Isl2 (rno-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 rno4080   Neuroactive ligand-receptor interaction  4 238 2.24
 rno4934   Cushing syndrome  3 141 2.05
 rno4024   cAMP signaling pathway  2 217 -
 rno4020   Calcium signaling pathway  3 238 -
 rno4060   Cytokine-cytokine receptor interaction  2 269 -

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rno:Isl2 (ISL LIM homeobox 2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

rno-u.3
for
Isl2
rno-r.3
for
Isl2
rno-m.5
for
Isl2
rno-u.3
for
Lmo1
rno-u.3
for
Isl1
mmu-u.4
for
Isl2
mmu-u.4
for
Isl1
hsa-u.4
for
ISL2
hsa-u.4
for
ISL1
gga-u.3
for
ISL2
gga-u.3
for
ISL1
dre-u.3
for
isl2b
dre-u.3
for
isl2a
dme-u.3
for
tup
cel-u.3
for
mec-3
cel-u.3
for
lim-7
1 Cngb1 cyclic nucleotide gated channel subunit beta 1 83686 6.3 1.5
 4.5
 0.4
 0.7



1.0
-0.2
 0.9
0.5
 -0.0
-0.9
 0.7
-0.4
 0.4
 1.1
 -0.2
2 Shc2 SHC adaptor protein 2 314612 4.5 1.0
 3.4
 2.3
0.9
 1.0
0.7
 1.7
1.3
 1.2
0.9
 0.5
0.4
 0.6
0.4
 1.3
0.5
 1.7
0.5
 2.0
1.4
 2.5
0.7
 0.7
 -0.2
 -0.0
3 Crx cone-rod homeobox 60446 4.5 1.4
 2.9
 0.5
0.1
 1.8
1.6
 2.9
2.9
 2.5
0.8
 5.0
0.6
 2.4
1.0
 1.0
0.1
 1.3
0.7
 4.8
4.0
 3.4
2.5
 5.0
 0.0
-0.6
 3.9
3.0
4 Htr3b 5-hydroxytryptamine receptor 3B 58963 4.3 1.8
 2.3
 1.8
 4.2










5 Scn11a sodium voltage-gated channel alpha subunit 11 29701 4.2 0.9
 3.2
 1.0
0.5
 3.6
2.6
 3.2
2.7
 5.6
3.4
 1.3
0.5
 0.6
0.4
 1.3
0.5
 1.4
1.1
 1.6
0.7
 1.1
1.0
 -0.5

6 Zcchc3 zinc finger CCHC-type containing 3 690005 4.1 0.4
 3.6
 0.4
 -0.4
 -0.4
 0.9
 1.2
 0.1






7 Pou4f1 POU class 4 homeobox 1 114503 4.1 1.4
 2.6
 1.1
 2.8
 4.5
 2.9
 4.5
 2.2
 2.0
1.5
 2.3
1.5
 6.5
5.7
 4.9
3.5
 1.1
 2.1
 2.9
8 Casz1 castor zinc finger 1 313713 4.1 0.7
 3.3
 -0.1
 2.2

-0.0
 0.5
 1.1
 2.0
 0.3
 0.2
 1.1

9 Six3 SIX homeobox 3 78974 4.1 0.8
 3.1
 0.7
 3.5
 2.4
 5.8
 2.2
1.0
 3.5
1.5
 2.6
0.1
 2.4
1.2
 5.2
4.0
 4.1
3.6
 4.0
 -0.7
 6.9
10 Chrnb4 cholinergic receptor nicotinic beta 4 subunit 25103 4.0 1.2
 2.7
 0.8
-0.1
 3.5
1.7
 4.2
1.7
 2.5
0.6
 0.7
 0.3
 0.6
0.4
 1.8
0.0
 2.9
0.4
 2.2
0.8


11 Crybb2 crystallin, beta B2 25422 3.9 0.7
 3.1
 -0.5
 1.2
 3.6
 0.9

-0.4
 -1.0
 0.2
 -0.1


12 Akp3 alkaline phosphatase 3, intestine, not Mn requiring 64621 3.9 0.9
 2.9
 0.7
0.6
 0.8
 2.6
2.2
 0.4
0.2
 0.9
0.7
 1.7
0.5
 0.1
-0.1
 -0.5
-0.6
 1.0
-0.5
 2.9
0.3
 1.6
1.2

13 Tmem233 transmembrane protein 233 687797 3.9 0.7
 3.0
 1.0
 2.0
 1.4
 1.6

-0.4
 1.4




14 Tsks testis-specific serine kinase substrate 292890 3.8 1.7
 2.0
 0.7
 -0.2
 1.8
 -0.2








15 Kcnip1 potassium voltage-gated channel interacting protein 1 65023 3.8 0.8
 2.9
 0.7
0.4
 1.4
1.2
 1.5
0.5
 2.2
0.4

0.1
-0.3
 2.3
1.0
 1.4
0.7
 1.8
0.3
 1.0

16 Kcnh6 potassium voltage-gated channel subfamily H member 6 116745 3.8 1.3
 2.3
 0.5
0.2
 3.4
2.2
 1.2
 2.4
 1.0
 1.1
 0.7
0.6
 2.1
2.0
 0.5
0.2
 0.8
0.5
 -1.1
 -0.8
 1.4
17 Tyrp1 tyrosinase-related protein 1 298182 3.8 1.3
 2.3
 0.6
-0.0
 1.9
1.8
 0.4
0.3
 0.4
-0.4
 -0.3
-0.4
 1.4
1.0
 0.6
-0.3
 0.6
-0.7
 1.7
1.4
 0.7
0.0


18 Wnt6 Wnt family member 6 316526 3.7 0.9
 2.7
 0.1
 0.3
 1.9
 0.0
 3.9
 1.1
 -0.5
 -0.4

1.5

19 Aipl1 aryl hydrocarbon receptor-interacting protein-like 1 59110 3.7 1.8
 1.8
 -0.4
-0.8
 0.7
0.5
 2.3
-0.5
 0.5
-0.7
 0.5
0.3
 1.2
0.2
 0.5
0.3
 0.2
-0.4
 1.2
-0.4
 0.7
0.4
 -1.5
 0.8
 -0.2
20 Vwa7 von Willebrand factor A domain containing 7 309611 3.7 0.8
 2.8
 -0.2
 -0.2
 1.5
 0.3
 0.2
 -0.2

0.3
 -0.3


21 Cntfr ciliary neurotrophic factor receptor 313173 3.7 0.6
 3.0
 1.5
 0.2
 1.7
 0.1
 0.3
 1.0
 -0.2
 2.7
 0.7
 0.9


22 Lhx4 LIM homeobox 4 360858 3.7 1.7
 1.9
 0.8
-0.3
 1.0
0.1

1.5
 -0.4
 1.8
0.5
 3.1
2.9
 5.0
3.5
 3.0
2.1
 5.4
 0.6
 1.5
23 Ggn gametogenetin 292765 3.6 1.2
 2.3
 0.4
 1.4










24 Hrh1 histamine receptor H 1 24448 3.6 0.2
 3.3
 1.8
 -0.0
 -1.1
 -1.0
 -0.8
 -0.8
 -1.1
 0.6




25 Zdhhc22 zinc finger DHHC-type palmitoyltransferase 22 299211 3.5 0.6
 2.8
 0.1
 1.4
 1.5
 0.0
 1.4
 0.7
 -0.6
 0.7




26 Kcng2 potassium voltage-gated channel modifier subfamily G member 2 307234 3.5 0.7
 2.7
 1.6
 -1.2
 2.2
 -1.6








27 Fabp9 fatty acid binding protein 9 64822 3.5 1.3
 2.1
 1.4
1.0
 2.0
0.3
 0.9
0.5
 0.1
0.0
 -0.7
-0.8
 0.2
-0.1
 0.3
-0.6
 0.1
-0.5
 1.9
1.0
 -0.1
-0.5
1.3
-0.0
 0.6
-0.1
28 Slc26a10 solute carrier family 26, member 10 366909 3.5 0.6
 2.8
 1.1
 -0.4
 -0.4
 -0.6



-0.3
 -0.3


29 Exosc6 exosome component 6 307850 3.5 0.6
 2.8
 0.2
 -0.7

2.6
 -0.7
 2.3
 0.0
 0.7
 0.2


30 Cacna1i calcium voltage-gated channel subunit alpha1 I 56827 3.5 0.9
 2.5
 3.0
1.2
 1.5
-0.1
 0.9
-0.1
 2.1
0.1
 0.8
0.6
 0.6
-0.8
 1.6
0.9
 2.5
0.6
 1.1
0.0
 0.6
-0.1
 0.8
 1.0
 1.0
31 Asphd1 aspartate beta-hydroxylase domain containing 1 293498 3.5 0.5
 2.8
 -0.9
 -0.0
 0.9
 1.2
 0.1
 -0.3






32 Mcu mitochondrial calcium uniporter 294560 3.5 -0.1
 3.5
 -0.5
 0.6
 0.7
 -0.4
 0.7
 -0.4
 0.1
 -0.4
 0.7
 -0.2
 0.3
 -1.7
 0.6
33 Tbx2 T-box transcription factor 2 303398 3.5 0.9
 2.4
 -0.3
 0.3
 2.0
 1.0
 2.5
 0.4
 2.4
 -0.2
 4.9
4.4
 6.4
4.6
 3.6
 1.7
 3.6
34 Tulp1 TUB like protein 1 309900 3.4 1.5
 1.8
 1.1
0.2
 1.5
1.5
 1.9
1.5
 0.7
0.4
 0.6
-0.1
 0.3
-0.1
 0.6
-0.6
 0.9
-0.5
 0.8
0.1
 0.4
-0.7
 1.2
 0.4
 0.8
35 Fam229a family with sequence similarity 229, member A 500554 3.4 0.5
 2.8
 0.4
 -0.3

1.3
 -0.2






36 Usp49 ubiquitin specific peptidase 49 316211 3.4 0.8
 2.5
 -0.1
 1.0
 2.8
 0.2
 1.4
 -0.2
 1.0
 -0.8




37 Insl3 insulin-like 3 114215 3.4 0.7
 2.6
 0.2
 -0.5

0.9
 -0.6






38 Amh anti-Mullerian hormone 25378 3.4 0.7
 2.6
 0.4
 -1.3
 3.3
 -0.5
 2.2
 -0.4
 1.6
 -1.0
 -1.1
 0.5


39 Tmem132e transmembrane protein 132E 287564 3.4 0.7
 2.5
 1.6
0.6
 1.3
0.9
 2.5
0.5
 1.5
1.5
 1.2
0.5
 1.9
1.4
 1.4
0.7
 1.4
1.0
 3.6
2.6
 1.6
1.3
 -0.5
 1.6
 0.6
40 Bglap bone gamma-carboxyglutamate protein 25295 3.4 0.6
 2.6
 0.4
 1.2
 2.7
0.5
 0.5
-0.3

0.6
 -0.5
 0.6
-1.0
 0.1
0.1


41 Klhl35 kelch-like family member 35 308850 3.4 1.2
 2.0
 0.7
 0.4

0.4
 0.7
 -0.8
 1.1




42 Slain1 SLAIN motif family, member 1 361087 3.3 0.1
 3.1
 1.6
 1.1
 0.1
 0.2
 -0.3
 -0.1
 0.2
 1.3
 1.5
 1.6


43 Insm2 INSM transcriptional repressor 2 314131 3.3 0.5
 2.7
 2.7
-0.6
 1.4
0.8
 2.1
 3.7
 2.4
2.4
 1.8
1.7
 1.9
 3.2
 2.4
1.8
 2.2
1.1
 2.4
-0.5
 1.0
 2.2
44 RGD1561517 similar to chromosome 20 open reading frame 144 499927 3.3 0.9
 2.4
 0.7
 0.3
 2.4
 -0.4








45 Scn10a sodium voltage-gated channel alpha subunit 10 29571 3.3 0.6
 2.5
 1.0
0.5
 3.6
2.6
 3.2
2.7
 5.6
3.4
 1.3
0.5
 0.6
0.4
 1.3
0.5
 1.4
1.1
 1.6
0.7
 1.1
1.0
 -0.5

46 Socs1 suppressor of cytokine signaling 1 252971 3.3 0.9
 2.3
 0.9
 -0.5
 1.6
 -0.4
 2.0
 -0.9
 2.0
 -0.3
 -0.5
 -1.4


47 Spindoc spindlin interactor and repressor of chromatin binding 361719 3.3 0.5
 2.7
 0.9
 -0.1
 0.5
 -0.1
 2.0
 0.3






48 Lhfpl4 LHFPL tetraspan subfamily member 4 353230 3.3 0.2
 3.0
 1.0
0.0
 2.1
1.4
 1.8
1.6
 3.4
2.1
 0.1
 0.6
 2.1
0.4
 2.2
0.8
 1.4
1.0
 0.6
0.4
 -0.3
 0.2
 0.8
49 Ppy pancreatic polypeptide 24677 3.3 0.4
 2.7
 -1.1
 0.7
 -0.0
 1.2
 1.0
 1.7






50 Ajm1 apical junction component 1 homolog 362083 3.3 0.9
 2.2
 0.1
 -0.5
 1.6
 -0.9
 2.0
 0.4
 2.2
 0.3
 -0.3
-1.3
 -0.0
-0.4
 0.8
 0.0
 3.1
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