Orthologous genes in OrthoFinder**

Species Gene Description
 rno-u.3   Nkd1   NKD inhibitor of WNT signaling pathway 1 
 rno-r.3   Nkd1   NKD inhibitor of WNT signaling pathway 1 
 rno-m.5   Nkd1   NKD inhibitor of WNT signaling pathway 1 
 rno-u.3   Nkd2   NKD inhibitor of WNT signaling pathway 2 
 mmu-u.4   Nkd2   naked cuticle 2 
 mmu-u.4   Nkd1   naked cuticle 1 
 hsa-u.4   NKD2   NKD inhibitor of WNT signaling pathway 2 
 hsa-u.4   NKD1   NKD inhibitor of WNT signaling pathway 1 
 mcc-u.3   NKD2   NKD inhibitor of WNT signaling pathway 2 
 mcc-u.3   NKD1   NKD inhibitor of WNT signaling pathway 1 
 cfa-u.3   NKD2   NKD inhibitor of WNT signaling pathway 2 
 cfa-u.3   NKD1   NKD inhibitor of WNT signaling pathway 1 
 gga-u.3   NKD1   naked cuticle homolog 1 
 dre-u.3   100500933   naked cuticle-like protein 3 
 dme-u.3   nkd   naked cuticle 
 spo-u.3   SPBC725.10   putative tspO-like protein 

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Top 50 coexpressed genes to Nkd1 (rno-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 rno5200   Pathways in cancer  7 468 3.31
 rno5165   Human papillomavirus infection  6 301 3.55
 rno5217   Basal cell carcinoma  5 57 6.11
 rno5226   Gastric cancer  5 130 4.35
 rno4151   PI3K-Akt signaling pathway  5 301 2.68

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rno:Nkd1 (NKD inhibitor of WNT signaling pathway 1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

rno-u.3
for
Nkd1
rno-r.3
for
Nkd1
rno-m.5
for
Nkd1
rno-u.3
for
Nkd2
mmu-u.4
for
Nkd2
mmu-u.4
for
Nkd1
hsa-u.4
for
NKD2
hsa-u.4
for
NKD1
mcc-u.3
for
NKD2
mcc-u.3
for
NKD1
cfa-u.3
for
NKD2
cfa-u.3
for
NKD1
gga-u.3
for
NKD1
dre-u.3
for
100500933
dme-u.3
for
nkd
spo-u.3
for
SPBC725.10
1 Fgfr2 fibroblast growth factor receptor 2 25022 6.1 3.6
 2.2
 2.0
1.8
 2.0
1.8
 3.9
2.5
 3.5
2.1
 2.5
2.3
 1.4
1.1
 1.2
0.8
 2.6
1.2
 1.3
0.9
 3.0
0.9
 1.4
1.2
 4.1
1.7
2 Axin2 axin 2 29134 5.8 3.2
 2.3
 1.0
 3.3
 9.6
 2.8
 10.7
 4.1
 3.0
 -0.4
 3.7
 5.5
 0.4

3 Hhip Hedgehog-interacting protein 291936 5.4 2.5
 2.6
 1.4
 0.6
 3.4
 -0.0
 0.5
 0.4
 0.1
 -0.0
 -0.1
 0.6
 2.1

4 Foxf1 forkhead box F1 687536 5.3 2.1
 3.0
 1.9
1.8
 2.3
1.7
 3.7
2.1
 3.1
2.9
 1.8
1.3
 -0.2
-0.3
 0.6
0.6
 0.6
-1.3
 1.0
0.6
 1.0
0.7
 2.6
1.5

5 Gng8 G protein subunit gamma 8 245986 5.1 2.3
 2.6
 1.9
1.3
 2.1
1.9
 1.8
1.2
 2.4
2.2
 2.2
1.9
 1.0
0.3
 1.6
1.5
 1.3
1.1
 2.0
1.5
 0.8
0.5
 1.9
1.0
 0.4
-0.1
6 Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 66015 4.9 2.7
-0.4
 0.2
 1.1
 0.2
 0.0
 1.2
 -0.1
 -0.3
 -0.5
 -0.1


7 Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A 114004 4.7 2.2
 2.3
 1.2
0.3
 0.5
0.4
 3.7
-0.5
 1.3
1.3
 1.6
1.2
 1.5
0.2
 1.5
1.3
 0.1
-1.0
 -0.4
-1.2
 0.1
-0.6
 0.9
0.5
 0.3
 0.9
0.1
8 Mcam melanoma cell adhesion molecule 78967 4.6 1.8
 2.6
 2.1
 1.2
 1.7
 -0.4
 0.5
 1.7
 0.6
 0.3
 0.6
 0.4
 1.9
1.0

9 Fnbp1 formin binding protein 1 192348 4.2 2.0
 2.1
 2.4
0.8
 0.4
0.2
 1.2
0.4
 0.6
0.1
 0.3
0.2
 1.0
0.2
 0.8
-0.1
 0.5
-0.1
 0.1
-0.4
 1.6
-0.4
 1.3
0.7
 -0.1
10 Cpm carboxypeptidase M 314855 4.2 1.8
 2.2
 1.9
 1.9
 1.8
 -0.5
 -1.4
 -0.7
 -0.2
 -1.3
 -1.6
 0.9
 0.2
 -0.4
11 Amigo2 adhesion molecule with Ig like domain 2 300186 4.0 1.7
 2.1
 0.9
 0.5
 1.0
 -1.3
 -0.0
 1.8
 1.3
 -1.1
 0.9
 -0.9


12 Insc INSC, spindle orientation adaptor protein 293166 3.9 2.2
1.5
 0.9
 1.9



1.0
 0.8
2.1
 1.4
13 Prr5l proline rich 5 like 362171 3.9 1.9
 1.9
 2.3
0.7
 0.4
0.1
 2.8
2.0
 2.4
-0.8
 1.6
1.3
 0.3
-1.0
 1.1
0.9
 0.5
-0.2
 1.5
-0.8
 -0.2
-0.3
 0.2
-0.1

14 Itgb3 integrin subunit beta 3 29302 3.9 2.2
1.4
 0.4
 -0.3
 -1.3
 -0.7
 -0.4
 1.1
 0.2
 -2.3
 0.9
 -0.5

15 Cybrd1 cytochrome b reductase 1 295669 3.9 2.1
 1.7
 1.2
 3.7
 2.5
 -0.8
 -1.0
 -1.1
 -0.1
 -1.1
 -0.9
 -0.4
 0.3

16 Tcf7 transcription factor 7 363595 3.9 2.1
 1.7
 2.5
1.6
 3.8
2.7
 4.4
4.3
 1.9
1.4
 5.3
3.5
 4.7
2.1
 3.5
1.3
 0.5
-1.7
 4.6
2.3
 2.9
2.3
 1.7
1.5
 1.9
 0.7
17 Nipal4 NIPA-like domain containing 4 303070 3.9 2.2
0.7
 2.0
 2.2
 -0.3
 0.4

-0.6
 -0.1
 -0.2
 0.7

18 Spon2 spondin 2 171569 3.8 1.9
 1.8
 1.6
 -0.4
 1.8
 1.2
 0.3
 0.6
 1.4
 0.6
 0.9
 -0.6
 1.7
1.5
 1.3
19 Nacad NAC alpha domain containing 289786 3.8 1.6
 2.1
 2.0
-1.1
 1.6
-0.1
 3.1
0.3
 1.1
0.2
 -0.1
-0.1
 1.8
0.6
 0.4
-0.0
 0.9
0.7
 0.7
-0.0
 0.8
0.3
 0.3
-0.0
 1.2
-0.1
20 Lef1 lymphoid enhancer binding factor 1 161452 3.8 2.1
 1.6
 2.5
1.6
 3.8
2.7
 4.4
4.3
 1.9
1.4
 5.3
3.5
 4.7
2.1
 3.5
1.3
 0.5
-1.7
 4.6
2.3
 2.9
2.3
 1.7
1.5
 1.9
 0.7
21 Ccnjl cyclin J-like 303059 3.8 2.0
 1.6
 1.4
0.6
 1.4
-0.7
 3.2
1.8
 1.4
0.6
 1.5
0.0
 1.0
-0.2
 -0.3
-0.6
 1.1
0.2
 0.8
-1.2
 0.7
0.7
 -0.1
-0.2
 -0.7
22 Arhgef10 Rho guanine nucleotide exchange factor 10 306618 3.7 1.8
 1.9
 0.7
-0.7
 1.3
-1.0
 2.0
-0.1
 1.1
-0.5
 0.5
-0.2
 0.3
-0.4
 0.4
0.3
 2.2
1.8
 -1.0
-1.0
 1.2
-0.3
 0.6
0.0
 2.0
23 Aatk apoptosis-associated tyrosine kinase 690853 3.7 2.2
 1.4
 1.6
 0.2
 2.1
 2.3
 0.8
 0.3
 0.3
 2.3
 0.2
 0.9
 1.0
0.7

24 Fzd10 frizzled class receptor 10 363913 3.7 2.0
1.0
 2.5
 4.2
 4.7
 4.9
 2.4
 0.6
 0.2
 3.7
 1.9
 0.2

25 Hr HR, lysine demethylase and nuclear receptor corepressor 60563 3.6 1.4
 2.1
 1.0
 1.1
 1.4
 1.4
 0.9
 -0.2
 -1.0
 -0.0
 -0.1
 0.2


26 Ngfr nerve growth factor receptor 24596 3.6 2.3
 1.2
 1.0
 1.4
 2.7
 3.1
 2.3
 0.8
 1.1
 2.0
 0.6
 -0.4
 3.1

27 Kank4 KN motif and ankyrin repeat domains 4 313385 3.6 1.9
 1.6
 1.5
 4.5
 2.7
 1.7
 2.4
 -0.3
 -0.3
 1.5
 0.3
 0.5
 -0.5
-0.8

28 Cldn11 claudin 11 84588 3.5 2.2
 1.2
 0.3
 -0.1
 1.3
 1.1
 1.7
 0.6
 0.5
 1.8
 1.0
 1.8
 0.9

29 Klk6 kallikrein related-peptidase 6 29245 3.5 1.5
 1.9
 0.8
0.5
 2.5
2.2
 1.1
0.0
 1.4
0.4
 2.0
0.8
 0.1
-0.0
 -0.2
-0.8
 0.8
0.1
 -0.2
-0.3
 0.5
0.0
 1.9
0.1
 1.1
0.3
 -0.6
-0.8
30 Gjb1 gap junction protein, beta 1 29584 3.5 2.0
 1.4
 -0.5
 -1.8
 1.1
 -0.5
 2.0
 0.6
 1.0
 -0.0
 1.0
 -0.0
 0.3

31 Gjc2 gap junction protein, gamma 2 497913 3.4 2.6
 0.7
 0.7
 0.8
 4.3
 1.1
 1.5
 2.1
 2.9

1.9


32 Ccdc3 coiled-coil domain containing 3 498795 3.4 1.9
1.4
 1.0
 2.0
 1.2
 2.5

0.1
 0.4
 0.4
 1.8

33 Cdc42ep1 CDC42 effector protein 1 315121 3.4 1.9
 1.4
 0.3
 0.4
 3.0
 0.0
 1.1
 1.0
 -0.1
 2.2
 -0.4
 1.1
 1.1
0.5

34 Ermn ermin 295619 3.4 1.8
 1.5
 0.0
 -1.5
 0.8
 -1.9
 0.9
 -0.1
 -0.7

-0.2


35 Art4 ADP-ribosyltransferase 4 312806 3.4 1.9
0.1
-0.3
 0.7
0.4
 0.7
-0.1
 -0.8
 0.1
 -1.1
 -0.2
 -1.0
 -1.2
 0.8
-0.0


36 Oca2 OCA2 melanosomal transmembrane protein 100365773 3.4 1.9
1.1



0.6
 0.2
 0.0
 1.0
 1.1
-0.1
-1.0
 -0.9
37 Tnfrsf11a TNF receptor superfamily member 11A 498206 3.4 2.1
 1.1
 0.8
 0.2
 -0.5
 0.4
 0.3
 0.7
 0.4
 1.0
 -0.3
 -0.4
 1.0

38 Apcdd1 APC down-regulated 1 689616 3.4 1.9
3.5
 3.3
 6.7
 3.0
 5.2
 0.9
 0.3
 0.3
 2.8
 4.4


39 Col9a3 collagen type IX alpha 3 chain 362285 3.3 2.0
 1.3
 2.6
 1.3
 1.3
 3.3
 3.6
 0.4
 -0.1
 0.1
 0.2
 -0.3
 0.2

40 Galnt6 polypeptide N-acetylgalactosaminyltransferase 6 100361647 3.3 1.9
-0.1
 -0.2
 0.7
 -0.3
 -0.5
 0.3
 0.1
 0.1
 -0.6
 -0.2
 -0.4

41 Ackr4 atypical chemokine receptor 4 685243 3.3 1.4
 1.8
 1.8
 2.0
 0.7
 0.0
 -0.9
 -1.7
 -0.6
 -0.3
 0.9
 0.7
 0.6

42 Col13a1 collagen type XIII alpha 1 chain 499431 3.3 2.3
 0.9
 2.6
 2.1
 4.9
 0.9
 1.1
 1.5
 1.5
 1.3
 0.8
 1.2
 1.3

43 Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like 362268 3.3 1.8
1.6
-0.6
 -0.9
 -0.4
 -0.4
 -0.5
 -0.4
 -0.0
 -0.1
 -0.8
 2.1
-0.1
 0.1
-0.5
 1.2
 -0.2
44 Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 84406 3.3 1.5
 1.7
 0.6
 0.2
 1.4
 -0.5
 1.0
 -0.1
 -0.7
 -0.9
 -0.5
0.5
-0.3
0.4
45 Eln elastin 25043 3.3 1.4
 1.7
 0.2
 2.7
 4.2
 0.9
 2.1
 1.3
 1.3
 1.2
 1.2



46 Nkx6-2 NK6 homeobox 2 309095 3.3 1.9
 1.3
 0.6
-0.6
 0.4
 1.6
 2.6
1.7
 1.0
0.8
 2.2
 0.3

0.3
-0.2
 1.2
0.7
 1.5
47 Unc5b unc-5 netrin receptor B 60630 3.2 1.6
 1.5
 1.1
0.8
 2.0
0.9
 2.6
0.9
 2.7
1.5
 1.5
1.2
 0.3
0.1
 0.2
0.1
 2.0
1.6
 0.3
0.3
 2.0
0.6
 1.1
0.4
 3.8
48 Rasl12 RAS-like, family 12 315762 3.2 1.6
 1.6
 2.6



1.0
 0.2
 -0.2
 -0.2
 -0.5
 0.3

49 Pmp22 peripheral myelin protein 22 24660 3.2 2.0
 1.1
 1.1
 -0.5
 2.1
 0.5
 0.4
 -0.5
 -0.2
 -0.5
 -0.8
 2.0
 -0.4

50 Fez1 fasciculation and elongation protein zeta 1 81730

1.1
0.6
 1.3
-0.2
 -0.1
-0.3
 -0.0
-0.6
 0.2
-0.1
 -0.1
-0.2
 1.2
0.4
 0.1
-0.3
 2.9
-0.6
 0.7
0.7
 1.1
0.6
 -0.4
 -0.2
-0.7
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