Orthologous genes in OrthoFinder**

Species Gene Description
 rno-u.3   Crem   cAMP responsive element modulator 
 rno-r.3   Crem   cAMP responsive element modulator 
 rno-m.5   Crem   cAMP responsive element modulator 
 rno-u.3   Atf1   activating transcription factor 1 
 mmu-u.4   Creb1   cAMP responsive element binding protein 1 
 hsa-u.4   ATF1   activating transcription factor 1 
 hsa-u.4   CREB1   cAMP responsive element binding protein 1 
 mcc-u.3   ATF1   activating transcription factor 1 
 mcc-u.3   CREB1   cAMP responsive element binding protein 1 
 cfa-u.3   CREB1   cAMP responsive element binding protein 1 
 cfa-u.3   CREM   cAMP responsive element modulator 
 cfa-u.3   ATF1   activating transcription factor 1 
 gga-u.3   CREB1   cAMP responsive element binding protein 1 
 gga-u.3   ATF1   activating transcription factor 1 
 dre-u.3   creb1b   cAMP responsive element binding protein 1b 
 dre-u.3   creb1a   cAMP responsive element binding protein 1a 
 dre-u.3   atf1   activating transcription factor 1 
 dme-u.3   CrebB   Cyclic-AMP response element binding protein B 
 cel-u.3   crh-1   BZIP domain-containing protein 
 spo-u.3   vma10   putative V-type ATPase V1 domain subunit G 

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Top 50 coexpressed genes to Crem (rno-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 rno5202   Transcriptional misregulation in cancer  4 166 2.80
 rno4010   MAPK signaling pathway  4 265 2.08
 rno4064   NF-kappa B signaling pathway  2 98 -
 rno4068   FoxO signaling pathway  2 134 -
 rno4022   cGMP-PKG signaling pathway  2 171 -

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rno:Crem (cAMP responsive element modulator) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

rno-u.3
for
Crem
rno-r.3
for
Crem
rno-m.5
for
Crem
rno-u.3
for
Atf1
mmu-u.4
for
Creb1
hsa-u.4
for
ATF1
hsa-u.4
for
CREB1
mcc-u.3
for
ATF1
mcc-u.3
for
CREB1
cfa-u.3
for
CREB1
cfa-u.3
for
CREM
cfa-u.3
for
ATF1
gga-u.3
for
CREB1
gga-u.3
for
ATF1
dre-u.3
for
creb1b
dre-u.3
for
creb1a
dre-u.3
for
atf1
dme-u.3
for
CrebB
cel-u.3
for
crh-1
spo-u.3
for
vma10
1 Coq10b coenzyme Q10B 301416 9.1 4.7
 3.9
 1.6
-0.3
 -0.1
-1.5
 2.0
1.7
 0.5
-1.5
 1.3
0.3
 0.3
-1.6
 2.4
-0.8
 4.0
0.2
 1.3
-0.1
 -0.9
-1.2
 1.0
-0.6
 -0.4
-0.5
 -1.1
-1.3
 2.2
-0.2
 -0.4
 0.6
2 Nr4a3 nuclear receptor subfamily 4, group A, member 3 58853 6.7 3.5
 2.9
 0.2
-0.1
 -0.0
-0.3
 0.7
0.7
 0.1
-0.3
 0.6
0.4
 -0.1
-0.3
 -0.0
-0.2
 4.7
4.0
 1.3
0.3
 0.9
0.0
 0.3
-0.2
 0.8
0.7
 1.2
0.9
 1.0
0.5
 0.5
 3.2
 -1.4
3 Nfil3 nuclear factor, interleukin 3 regulated 114519 6.5 3.2
 3.0
 0.5
 0.1
 0.8
 0.8
 1.4
 0.2
 -0.3
 4.2
 1.3
 0.6
 -0.6
 3.0
 1.4
 -0.9


4 Slc25a25 solute carrier family 25 member 25 246771 6.1 3.4
 2.4
 2.7
1.2
 0.8
-0.6
 2.2
0.3
 0.3
-1.2
 1.0
0.8
 0.4
-0.3
 1.9
-1.1
 1.4
-0.0
 1.2
0.3
 1.0
-0.5
 0.4
-0.4
 0.8
-0.1
 0.5
-0.5
 1.4
1.1
 1.8
 -0.4
-1.3
 0.8
0.4
5 Sik1 salt-inducible kinase 1 59329 5.9 3.3
 2.4
 1.7
 -1.3
 -0.2
 -0.6
 -0.2
 -0.3
 -0.6
 2.3
 -0.0
 0.6
 0.3
 -1.0
 -0.3
 0.6


6 Arl5b ADP-ribosylation factor like GTPase 5B 364788 5.8 3.2
1.0
0.4
 4.3
3.4
 3.0
2.0
 1.5
-0.4
 2.1
0.8
 2.6
1.8
 3.3
3.3
 3.6
-1.2
 0.6
-0.2
 2.7
-1.0
 1.5
0.3
 0.9
0.8
 1.8
0.6
 1.6
1.6
 -0.9
 0.1
7 Nr4a1 nuclear receptor subfamily 4, group A, member 1 79240 5.6 3.2
 2.1
 0.2
-0.1
 -0.0
-0.3
 0.7
0.7
 0.1
-0.3
 0.6
0.4
 -0.1
-0.3
 -0.0
-0.2
 4.7
4.0
 1.3
0.3
 0.9
0.0
 0.3
-0.2
 0.8
0.7
 1.2
0.9
 1.0
0.5
 0.5
 3.2
 -1.4
8 Nr4a2 nuclear receptor subfamily 4, group A, member 2 54278 5.5 2.1
 3.1
 0.2
-0.1
 -0.0
-0.3
 0.7
0.7
 0.1
-0.3
 0.6
0.4
 -0.1
-0.3
 -0.0
-0.2
 4.7
4.0
 1.3
0.3
 0.9
0.0
 0.3
-0.2
 0.8
0.7
 1.2
0.9
 1.0
0.5
 0.5
 3.2
 -1.4
9 Rgs2 regulator of G-protein signaling 2 84583 5.2 2.6
 2.4
 -0.4
 0.4
 -0.1
 0.6
 -0.1
 -0.3
 0.4
 2.2
 0.1
 -0.5
 0.6
 0.2
-0.1
 0.1
0.1
 0.9
0.3
4.5
1.7
10 Birc2 baculoviral IAP repeat-containing 2 60371 5.2 3.0
 2.0
 1.5
-0.0
 3.6
3.0
 1.8
1.1
 0.7
0.7
 2.1
1.5
 3.0
2.6
 1.8
0.5
 1.6
1.4
 3.4
2.0
 1.1
-0.2
 0.4
0.2
 0.8
0.2
 0.8
0.3
 0.9
0.2
 0.7
0.1
 0.3
11 Tiparp TCDD-inducible poly(ADP-ribose) polymerase 310467 5.1 2.9
 2.0
 2.0
 0.1
 -0.8
 -0.1
 0.2
 0.1
 1.3
 3.4
 -0.2
 -1.1
 1.2
 0.3
 0.9
 -1.2


12 LOC120095261 uncharacterized LOC120095261 120095261 5.1 2.8

















13 Errfi1 ERBB receptor feedback inhibitor 1 313729 4.7 2.8
 1.7
 2.3
 -0.4
 2.1
 0.2
 0.7
 -1.0
 0.9
 1.4
 0.9
 -0.6
 1.4
 0.3
 -1.5
 -0.9


14 Ell2 elongation factor for RNA polymerase II 2 309918 4.6 2.2
 2.2
 2.0
1.2
 -0.0
-3.6
 0.1
 0.2
 1.1
-0.1
 0.6
-0.2
 1.4
0.6
 1.8
1.2
 1.0
-0.0
 -0.8
-1.0
 2.5
0.2
 -0.4
-1.3
 1.2
-1.0
 0.2
-0.2
 1.4
0.4
15 Csrnp1 cysteine and serine rich nuclear protein 1 363165 4.5 2.2
 2.2
 1.3
0.3
 0.1
-0.3
 2.3
0.1
 1.9
1.5
 0.9
0.0
 0.9
0.6
 1.0
-0.1
 2.0
-1.3
 1.7
0.9
 2.0
0.5
 0.1
-0.1
 0.9
-0.5
 0.0
-0.6
 1.1
-0.6
 -0.6
 1.4
16 Fosl2 FOS like 2, AP-1 transcription factor subunit 25446 4.5 2.5
 1.8
 -0.4
 0.3
 0.5
 0.6
 0.2
 -1.0
 -0.7
 2.7
 1.2
 0.0
 -0.5
 -2.2
 -0.6
 -0.1


17 Gem GTP binding protein overexpressed in skeletal muscle 297902 4.5 2.5
 1.8
 1.3
 -0.7
 1.8
 -0.3
 -0.4
 -0.6
 -0.2
 0.1
 -0.1
 -0.1
 0.9





18 Tnfaip6 TNF alpha induced protein 6 84397 4.4 1.6
 2.7
 0.1
 0.2
 0.6
 0.6
 0.7
 1.1
 0.0
 -0.2
 0.6
 -0.6
 0.0
 -0.7
 -0.6
 -0.1


19 Mapkapk2 MAPK activated protein kinase 2 289014 4.4 2.5
 1.8
 2.7
1.4
 0.5
0.3
 0.5
-0.1
 0.4
0.2
 0.5
0.2
 -0.1
-1.0
 -1.0
-1.1
 1.4
0.8
 0.7
-0.5
 -0.3
-2.3
 0.5
0.1
 -0.1
-1.3
 0.3
-0.7
 4.1
-0.1
 1.0
 0.8
20 Snapc1 small nuclear RNA activating complex, polypeptide 1 314228 4.4 1.8
 2.4
 2.5
 2.8
 3.0
 0.3
 -0.1
 -0.0
 2.5
 1.3
 0.8
 -1.5
 1.0
 0.2
-0.4
 1.3
-1.1
 1.4
-0.7
 -0.6
 0.4
-0.4
 -1.3
21 Ifrd1 interferon-related developmental regulator 1 29596 4.3 2.4
 1.7
 2.6
2.2
 0.3
0.3
 1.8
0.9
 0.1
0.0
 1.4
0.2
 1.5
-0.6
 -0.6
-1.2
 0.9
0.5
 1.9
1.1
 -0.5
 1.0
 -1.3
-3.2
 0.1
-0.1
 0.2
-2.6
 1.8
 1.3
 0.9
22 Arid5a AT-rich interaction domain 5A 316327 4.3 1.7
 2.4
 0.8
 -0.3
 -1.1
 -0.6
 -0.3
 -0.2
 0.1
 2.3
 0.2
 -0.2
 0.5
 0.8
-0.8
 1.0
-0.7
 1.5
0.8

-0.1
23 Cebpb CCAAT/enhancer binding protein beta 24253 4.2 2.3
 1.8
 2.7
 -0.2
 1.9
 -1.3
 -0.5
 0.3
 -0.4
 2.5
 0.5
 -1.4
 0.2





24 Dusp1 dual specificity phosphatase 1 114856 4.2 2.2
 1.9
 0.5
 -1.0
 0.3
 -0.5
 1.4
 1.8
 -0.3
 2.7
 0.9
 -1.2
 -1.0
 -0.3
 0.8
 3.8


25 Gadd45g growth arrest and DNA-damage-inducible, gamma 291005 4.2 2.1
 1.9
 1.0
0.4
 -0.1
-0.1
 0.5
0.2
 -0.4
-1.2
 0.7
0.6
 0.5
0.4
 -0.6
-0.9
 3.5
2.4
 0.5
0.4
 -0.5
-1.1
 0.4
-0.3
 2.1
1.0
 2.3
2.0
 0.7
0.5
 2.5

26 Ptp4a1 protein tyrosine phosphatase 4A1 29463 4.2 2.7
 1.3
 3.9
3.7
 1.6
1.4
 2.0
1.6
 1.3
-0.2
 1.2
0.7
 0.8
0.2
 2.4
-0.4
 3.8
 2.9
-0.0
 0.5
0.3
 3.2
2.6
 0.2
-1.3
 2.3
1.0
 2.6
1.9
2.0
27 Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 498272 4.2 2.1
 1.9
 1.6
1.2
 1.1
-0.2
 0.9
-0.4
 -1.4
-1.6
 1.2
-0.2
 -0.5
-1.0
 1.5
-1.7
 1.3
-0.7
 1.9
-0.7
 1.9
-0.8
 0.8
-0.8
 -0.3
-1.7
 -1.4
-1.6
 0.4
-0.2
 0.9
 -1.0
 1.6
28 Trib1 tribbles pseudokinase 1 78969 4.2 2.0
 2.1
 0.8
-0.6
 1.1
0.3
 2.6
0.9
 0.6
-0.3
 1.1
0.7
 0.9
0.5
 1.0
0.4
 1.2
-0.0
 2.0
0.5
 1.7
-2.4
 1.6
0.5
 0.8
0.8
 1.1
-0.4
 1.0
0.6
 1.5

29 Helz2 helicase with zinc finger 2 296474 4.2 2.3
 1.7
 -0.5
 -0.2
 -1.2
 -0.0
 -0.4
 0.0


0.3
 -0.7
 -0.7
 0.1
 -0.5


30 Maff MAF bZIP transcription factor F 366960 4.2 2.3
 1.7
 2.4
2.1
 -0.4
-1.1
 0.5
0.5
 -0.9
-1.5
 -0.2
-0.5
 1.0
0.3
 -0.2
-1.5
 1.3
0.3
 0.2
-0.0
 -0.6
-1.1
 0.1
-0.1
 1.2
0.3
 2.3
0.6
 0.5
0.2
 -0.5
 1.0
31 Rnf138 ring finger protein 138 94196 4.1 2.4
 1.6
 3.6
 1.1
 2.4
 -0.3
 1.0
 0.1
 1.0
 1.6
 2.1
 -0.2
 -0.3





32 Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 295549 4.1 2.3
0.9
0.3
 2.1
1.2
 1.1
1.0
 1.0
0.7
 0.5
0.4
 2.2
0.9
 2.8
1.1
 1.2
0.9
 1.0
0.2
 0.8
0.4
 0.2
0.1
 0.8
0.8
 0.7
-0.8
 3.7
1.4
 0.4
0.0
 2.6
 -0.9
-1.0
33 Cldnd1 claudin domain containing 1 288182 4.1 2.0
 1.9
 2.6
 0.8
 2.6
 2.2
 0.1
 1.6
 1.2
 -0.2
 0.9
 0.8
 0.5
 1.7
 -0.2
 1.0


34 Dpm1 dolichyl-phosphate mannosyltransferase subunit 1, catalytic 296394 4.1 2.7
 1.3
 2.0
 -0.6
 2.9
 -1.4
 1.7
 -0.6
 0.4
 1.4
 3.4
 1.2
 0.6
 0.4
 -0.2
 -0.3
 -0.5
 0.0
 0.2
35 Spty2d1 SPT2 chromatin protein domain containing 1 100365259 4.1 2.3
2.5
 2.8
 1.8
 -0.0
 1.7
 0.2
 0.9
 0.5
 2.5
 -0.3
 2.0
 1.4
 0.7
 2.5
 -0.0

36 Irs2 insulin receptor substrate 2 29376 4.1 2.5
 1.4
 0.3
0.1
 1.3
-0.2
 1.5
1.1
 0.5
-1.6
 1.7
-0.9
 0.2
-0.1
 -0.8
-1.0
 1.1
-0.7
 0.7
0.3
 0.8
-1.6
 1.9
-0.2
 1.8
0.8
 0.6
0.2
 1.6
0.6
2.3
 0.3
-2.1
37 Zfp868 zinc finger protein 868 494340 4.0 2.1
 1.8
 3.1
3.1
 2.6
2.3














38 Smim14 small integral membrane protein 14 364154 4.0 2.2
 1.7
 0.6
 -0.4
 1.7
 0.4
 0.8
 -0.2
 1.3
 0.8
 3.0
 1.9
 -0.3
 -0.8
 -0.5
 0.9
 -0.9
 1.8
39 Rcan1 regulator of calcineurin 1 266766 3.9 2.1
 1.7
 0.9
0.4
 -0.5
-0.8
 0.6
-0.1
 0.5
-0.0
 1.0
-0.9
 1.4
0.3
 0.4
0.4
 1.6
0.9
 3.2
1.2
 1.5
1.3
 0.9
-0.7
 0.4
-0.1
 0.3
0.0
 1.5
0.2
 1.9
 1.3
40 Srxn1 sulfiredoxin 1 296271 3.9 1.5
 2.2
 0.1
 -1.4
 0.2
 -1.3
 -0.7
 -0.8
 -1.2
 0.6
 1.2
 -0.3
 -1.6
 -0.7
 0.3
 -0.5
 0.4

41 Tp53rk TP53 regulating kinase 362272 3.9 1.9
 1.9
 2.5
1.0
 2.1
1.0
 2.3
 -0.2
 0.8
 0.3
 -0.3
 0.2
 -0.1
 0.6
 1.5
 -1.4
 -0.8
 0.5
 -0.2
 0.2
42 Fbxo33 F-box protein 33 314157 3.9 2.0
 1.7
 1.9
 -0.1
 0.2
 -0.5
 -1.0
 -0.8
 1.8
 1.0
 -1.1
 2.2
 0.2
 -0.0
 0.3
 0.5
 1.6

43 Pex13 peroxisomal biogenesis factor 13 305581 3.9 2.4
 1.4
 2.4
 0.1
 1.2
 1.1
 1.6
 0.6
 2.0
 0.4
 2.8
 1.5
 0.7
 0.8
 0.8
 1.8
 1.9
 0.8
 -0.9
44 Tnfrsf12a TNF receptor superfamily member 12A 302965 3.9 1.5
 2.2
 2.0
 -1.0
 1.8
 -0.4
 1.1
 -0.9
 -0.5
 0.0
 -0.5







45 Uspl1 ubiquitin specific peptidase like 1 288447 3.9 2.1
 1.6
 2.8
 2.4
 0.4
 1.0
 1.4
 1.7
 2.5
 0.7
 0.8
 3.1
 1.9
 -0.0
 -1.1
 0.6


46 Emd emerin 25437 3.9 2.1
 1.6
 -0.3
 0.6
 0.4
 -1.1
 -0.8
 -0.8
 -0.4
 2.0
 1.3

3.3
-0.1
 1.6
1.5
 2.1
1.2


47 Ube2b ubiquitin-conjugating enzyme E2B 81816 3.9 2.3
 1.5
 1.9
0.2
 0.9
0.5
 1.9
1.1
 0.5
-0.6
 0.2
-2.1
 -0.2
-2.0
 2.9
-1.0
 1.7
1.0
 1.8
0.7
 0.6
-1.5
 2.1
0.3
 0.1
-0.4
 2.7
0.3
 2.0
0.8
 0.7
 1.4
 -0.6
48 Ntmt1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 362103 3.9 1.7
 2.0
 1.8
-0.3
 -0.6
 -1.8
 0.2
 -0.1
 2.5
 0.4
 -0.6
 0.4
 0.4
 0.3
 1.3
 1.1
 0.5
 0.0
49 Dnaaf2 dynein, axonemal, assembly factor 2 362746 3.8 2.1
2.5
 1.6
 3.2
 -0.3
 1.8
 -0.5
 0.7
 0.8
 1.1
 -0.4
 0.5
 -0.7
 -1.5
 -0.7
 -0.3

50 Ccnl1 cyclin L1 114121 3.8 2.1
 1.6
 1.9
 0.8
0.1
 0.6
-1.1
 1.5
0.3
 3.7
 2.8
 3.3
 2.9
 1.5
 -0.5
-1.0
 2.0
1.3
 1.3
-1.9
 0.6
-0.1
 1.7
0.8
 2.8
 0.5
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