Orthologous genes in OrthoFinder**

Species Gene Description
 rno-u.3   Optn   optineurin 
 rno-r.3   Optn   optineurin 
 rno-m.5   Optn   optineurin 
 mmu-u.4   Optn   optineurin 
 hsa-u.4   OPTN   optineurin 
 mcc-u.3   OPTN   optineurin 
 cfa-u.3   OPTN   optineurin 
 gga-u.3   OPTN   optineurin 
 dre-u.3   optn   optineurin 
 dme-u.3   key   kenny 

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Top 50 coexpressed genes to Optn (rno-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 rno4137   Mitophagy - animal  3 65 3.00
 rno4146   Peroxisome  3 85 2.66
 rno380   Tryptophan metabolism  2 42 2.15
 rno5012   Parkinson disease  3 270 -
 rno5022   Pathways of neurodegeneration - multiple diseases  4 477 -

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rno:Optn (optineurin) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

rno-u.3
for
Optn
rno-r.3
for
Optn
rno-m.5
for
Optn
mmu-u.4
for
Optn
hsa-u.4
for
OPTN
mcc-u.3
for
OPTN
cfa-u.3
for
OPTN
gga-u.3
for
OPTN
dre-u.3
for
optn
dme-u.3
for
key
1 Larp1b La ribonucleoprotein 1B 310348 6.3 3.4
 2.7
 0.7
 1.1
0.6
 1.9
0.7
 1.8
-1.3
 1.5
-1.4
 -0.6
-1.0
 -1.6
2 Rmdn3 regulator of microtubule dynamics 3 311328 4.8 2.1
 2.5
 3.6
 2.2
 1.6
 0.2
 -0.4
 2.7
1.6
3 Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A 24666 4.7 2.0
 2.4
 3.6
3.4
 3.3
0.5
 0.1
-0.2
 3.3
2.6
 3.1
1.3
 0.2
0.1
 2.6
2.1
4 Phyh phytanoyl-CoA 2-hydroxylase 114209 4.7 2.3
 2.2
 3.9
 4.1
 1.3
 2.2
0.6
 1.8
 -0.2
5 Usp15 ubiquitin specific peptidase 15 171329 4.6 2.5
 1.9
 0.7
-0.1
 1.0
-0.4
 1.3
1.0
 0.4
-0.9
 2.6
-0.6
 2.2
-0.4
6 Cdv3 CDV3 homolog 315970 4.5 2.6
 1.7
 1.2
 2.2
 2.0
 1.4
 -0.4
 -0.4
7 Pcyt1a phosphate cytidylyltransferase 1A, choline 140544 4.5 2.1
 2.2
 3.8
1.5
 2.0
-0.2
 1.1
-1.6
 1.4
-0.8
 0.4
-0.4
 2.2
1.3
 0.7
0.6
8 Usp47 ubiquitin specific peptidase 47 308896 4.3 2.1
 2.0
 2.8
 1.6
 1.9
 0.5
 2.2
 0.3
 1.7
9 Lrrfip2 LRR binding FLII interacting protein 2 301035 4.1 2.1
 1.9
 5.5
0.8
 3.0
 -0.0
 2.2
0.5
 5.9
10 Golga4 golgin A4 501069 4.1 2.8
 1.1
 3.4
 3.1
 2.5
 2.6
 0.5
 3.4
 2.3
11 Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha 170670 4.1 2.2
 1.7
 3.5
 2.7
 2.6
 2.1
 0.1
 0.6
0.6
 -0.5
12 Nadk2 NAD kinase 2, mitochondrial 365699 4.1 2.0
 2.0
 2.0
 -0.2
 0.0
 -0.3
 -1.8
 0.0
 0.4
13 Riok3 RIO kinase 3 361293 4.0 1.9
 1.9
 3.4
 5.9
 0.6
 -0.4
 0.1
 2.7
 3.9
14 Slc16a1 solute carrier family 16 member 1 25027 4.0 2.0
 1.9
 2.3
0.5
 0.9
0.4
 1.2
0.8
 1.5
1.0
 0.4
-0.3
 1.7
1.5
 3.6
1.2
15 Tlcd4 TLC domain containing 4 365924 4.0 1.9
 1.9
 2.1
 2.1
 -0.7
 1.0
 -1.0
 0.8
0.3
16 LOC120102950 uncharacterized LOC120102950 120102950 3.9 2.2







17 Nbn nibrin 85482 3.9 2.0
 1.7
 2.7
 -0.6
 1.0
 3.4
 3.3
 0.1
 -0.7
18 Prxl2a peroxiredoxin like 2A 361118 3.9 1.9
 1.8
 2.8
 1.6
 0.5
 0.4
 -0.5
 0.1
-0.5
19 Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 362293 3.8 1.9
 1.8
 3.4
2.8
 4.6
1.1
 0.9
 0.4
 2.3
0.0
 1.8
0.9
 1.6
20 Uhrf1bp1l UHRF1 binding protein 1-like 363009 3.8 2.3
 1.4
 2.2
1.4
 -0.3
-0.9
 1.3
-0.8
 0.5
-0.3
 1.2
0.9
 1.3
-0.5
 0.4
21 Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X 300786 3.8 2.2
 1.5
 1.6
 1.9
 0.6
 2.4
2.1
0.9
 0.4
22 Mfn2 mitofusin 2 64476 3.8 1.9
 1.7
 2.7
2.6
 1.4
1.0
 1.6
1.1
 0.2
0.1
 3.2
1.0
 1.2
-0.4
 -0.2
-0.5
23 Mapk6 mitogen-activated protein kinase 6 58840 3.7 1.9
 1.7
 1.1
 0.3
 3.2
 1.2
 2.2
 0.3
24 Dcaf6 DDB1 and CUL4 associated factor 6 289181 3.7 2.3
 1.3
 2.5
 5.3
 3.0
 3.3
 3.2
 2.0
25 Lpin1 lipin 1 313977 3.7 2.5
 1.2
 4.0
2.1
 2.4
1.6
 1.6
1.5
 0.8
-0.2
 2.1
-0.1
 1.9
1.9
 0.4
26 Mfap1a microfibrillar-associated protein 1A 499878 3.7 2.1
0.1
-0.2
 0.9
 0.8
 1.6
 0.8
 0.9
 2.7
27 Opa1 OPA1, mitochondrial dynamin like GTPase 171116 3.7 1.9
 1.7
 1.7
 1.5
 1.0
 2.0
 2.6
 1.7
 0.4
28 Abcf3 ATP binding cassette subfamily F member 3 287982 3.7 2.3
 1.3
 1.1
 -0.1
 2.4
 -0.7
 1.3
 -0.9
 -0.7
29 Crat carnitine O-acetyltransferase 311849 3.7 2.0
 1.6
 3.4
-0.7
 3.4
 1.3
 1.6
 1.2
 1.5
0.4
 1.0
0.3
30 Pstpip2 proline-serine-threonine phosphatase-interacting protein 2 307248 3.7 2.0
3.4
-0.2
 1.1
-0.2
 2.1
-0.8
 2.2
0.3
 0.6
-0.3
 1.6
-0.0
31 Ube2j1 ubiquitin-conjugating enzyme E2, J1 297961 3.7 2.1
 1.5
 1.4
 -0.0
 0.9
 0.5
 3.1
 0.4
32 Tmf1 TATA element modulatory factor 1 114206 3.7 2.0
 1.5
 1.4
 1.9
 1.0
 2.7
 3.2
 2.6
 1.1
33 Fxr1 FMR1 autosomal homolog 1 361927 3.7 2.0
 1.5
 2.2
0.9
 1.8
1.6
 2.3
0.9
 3.4
1.2
 3.6
3.1
 1.7
-0.2
 -0.7
34 Rabep1 rabaptin, RAB GTPase binding effector protein 1 54190 3.7 1.5
 2.0
 2.1
 1.1
 2.6
 2.0
 5.2
 1.9
35 Fgfr1op2 FGFR1 oncogene partner 2 362463 3.7 2.1
 1.5
 -0.7
-2.0
 3.2
-0.8
 1.1
-1.2
 0.0
-0.1
 1.5
0.4
 2.2
0.8
 1.8
36 Dcun1d1 defective in cullin neddylation 1 domain containing 1 310324 3.6 2.1
 1.4
 1.2
-0.3
 1.9
0.5
 1.2
-0.1
 1.6
1.1
 1.6
1.2
 2.2
1.5
 3.0
0.9
37 Nceh1 neutral cholesterol ester hydrolase 1 294930 3.6 2.0
1.1
0.1
 1.2
 -0.9
-1.3
 -0.4
-0.7
 1.2
0.4
 2.2
1.1
38 Oxr1 oxidation resistance 1 117520 3.6 2.3
 1.2
 0.9
 2.8
1.2
 0.6
-0.2
 2.2
1.4
 1.0
1.0
 1.2
0.8
 0.4
39 Vps26a VPS26 retromer complex component A 361846 3.6 2.3
 1.1
 3.4
-2.1
 2.7
-0.1
 2.0
0.5
 0.9
0.0
 1.8
-0.0
 2.2
1.2
 2.3
40 Arhgef37 Rho guanine nucleotide exchange factor 37 307398 3.6 2.0
1.7
1.0
 2.2
-0.8
 0.7
-0.9
 -0.0
-0.3
 0.6
-0.7
 0.8
0.7
 1.7
41 Zfp91 zinc finger protein 91 246282 3.6 2.2
 1.3
 0.9
 0.4
 2.0
 0.6
 2.0
 -1.2
42 Clec16a C-type lectin domain containing 16A 287044 3.6 1.7
 1.7
 0.4
 1.2
 1.1
 -0.6
 0.8
 2.0
 1.9
43 Ddit3 DNA-damage inducible transcript 3 29467 3.6 1.5
 2.0
 2.3
 1.1
 1.7
 1.4
3.5
44 Ccpg1 cell cycle progression 1 363098 3.6 2.1
 1.3
 0.6

2.2
 2.6
 1.5
45 Nbr1 NBR1, autophagy cargo receptor 303554 3.6 2.0
 1.4
 1.7
 2.2
 1.0
 2.0
 1.7
 2.6
2.3
46 Kpna1 karyopherin subunit alpha 1 288064 3.5 2.0
 1.5
 1.6
0.4
 1.3
1.1
 0.3
0.1
 0.9
-0.5
 1.9
1.6
 1.1
-1.7
 1.6
47 Ghitm growth hormone inducible transmembrane protein 290596 3.5 1.8
 1.6
 3.0
 2.7
 1.2
 0.0
 1.5
 -0.2
 -0.1
-0.1
48 Ecpas Ecm29 proteasome adaptor and scaffold 313196 3.5 1.9
 1.5






49 Cat catalase 24248 3.5 1.8
 1.6
 2.1
 0.0
 -1.6
 0.2
 -0.2
 -0.7
 0.3
-0.6
50 Cebpg CCAAT/enhancer binding protein gamma 25301 3.5 1.1
 2.2
 1.2
 1.9
 2.4
 -0.7
 2.1
 2.3
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