Orthologous genes in OrthoFinder**

Species Gene Description
 rno-u.3   Pde4b   phosphodiesterase 4B 
 rno-r.3   Pde4b   phosphodiesterase 4B 
 rno-m.5   Pde4b   phosphodiesterase 4B 
 rno-u.3   Pde4d   phosphodiesterase 4D 
 rno-u.3   Pde4a   phosphodiesterase 4A 
 mmu-u.4   Pde4c   phosphodiesterase 4C, cAMP specific 
 mmu-u.4   Pde4d   phosphodiesterase 4D, cAMP specific 
 mmu-u.4   Pde4a   phosphodiesterase 4A, cAMP specific 
 hsa-u.4   PDE4A   phosphodiesterase 4A 
 mcc-u.3   PDE4D   phosphodiesterase 4D 
 mcc-u.3   PDE4A   phosphodiesterase 4A 
 cfa-u.3   PDE4A   phosphodiesterase 4A 
 cfa-u.3   PDE4C   phosphodiesterase 4C 
 gga-u.3   PDE4C   phosphodiesterase 4C 
 gga-u.3   PDE4B   phosphodiesterase 4B 
 dre-u.3   pde4ca   phosphodiesterase 4C, cAMP-specific a 
 dre-u.3   pde4cb   phosphodiesterase 4C, cAMP-specific b 
 dme-u.3   dnc   dunce 
 sce-u.3   PDE2   3',5'-cyclic-nucleotide phosphodiesterase PDE2 
 spo-u.3   lkh1   dual-specificity 

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Top 50 coexpressed genes to Pde4b (rno-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 rno4668   TNF signaling pathway  9 101 6.24
 rno4064   NF-kappa B signaling pathway  7 88 6.60
 rno5134   Legionellosis  6 52 6.32
 rno5167   Kaposi sarcoma-associated herpesvirus infection  6 172 4.90
 rno5169   Epstein-Barr virus infection  6 185 4.72

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rno:Pde4b (phosphodiesterase 4B) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

rno-u.3
for
Pde4b
rno-r.3
for
Pde4b
rno-m.5
for
Pde4b
rno-u.3
for
Pde4d
rno-u.3
for
Pde4a
mmu-u.4
for
Pde4c
mmu-u.4
for
Pde4d
mmu-u.4
for
Pde4a
hsa-u.4
for
PDE4A
mcc-u.3
for
PDE4D
mcc-u.3
for
PDE4A
cfa-u.3
for
PDE4A
cfa-u.3
for
PDE4C
gga-u.3
for
PDE4C
gga-u.3
for
PDE4B
dre-u.3
for
pde4ca
dre-u.3
for
pde4cb
dme-u.3
for
dnc
sce-u.3
for
PDE2
spo-u.3
for
lkh1
1 Pde4d phosphodiesterase 4D 24627 4.3 2.7
 1.4
 4.3
2.7
 2.7
1.0
 1.4
0.0
 1.5
0.0
 1.5
1.4
 0.7
 2.1
2.0
 2.0
1.6
 0.6
0.2
 0.6
0.1
 2.8
 2.8
 3.3
1.5
 1.8
1.5


2 Sik1 salt-inducible kinase 1 59329 4.2 1.9
 2.2
 2.4
 -0.8
 1.6
 1.2
 1.0
 0.3
 2.4
 1.2
 1.1
 1.5
 0.8
 4.7
 2.2
 0.6


3 Acvr1b activin A receptor type 1B 29381 4.1 2.3
3.6
2.2
 1.9
1.6
 1.1
-0.1
 1.6
1.4
 1.8
1.0
 2.1
1.2
 2.5
2.5
 0.5
0.3
 1.4
0.8
 1.1
0.5
 1.4
1.3
 1.2
0.3
 1.3
0.9
 2.7
2.6
 1.0
-0.5
0.7
4 Rnd1 Rho family GTPase 1 362993 3.9 2.3
 1.4
 0.4
 -0.1
 -0.0
 -0.6
 1.0
 -0.3
 -0.1
 -0.4
 1.1
 0.9
 0.4
 0.5
 0.4
 0.7
0.5


5 Mast4 microtubule associated serine/threonine kinase family member 4 103690045 3.9 2.1
2.4
 1.2
 -0.4
 1.5
 1.7


-1.4
 0.7
 0.4
 0.3
 1.8
 1.5


6 Il6 interleukin 6 24498 3.9 1.5
 2.2
 1.2
 -0.2
 -0.8
 0.2
 -0.6
 0.9
 0.2
 0.2
 0.3
 -0.4
 -1.0
 2.6




7 Cdk17 cyclin-dependent kinase 17 314743 3.8 2.0
 1.7
 1.7
0.1
 2.0
1.1
 1.1
0.0
 1.0
0.9
 2.9
2.2
 1.4
0.5
 1.6
1.6
 2.4
0.9
 1.1
0.7
 0.6
0.1
 0.9
0.3
 1.4
-0.6
 0.4
-0.1
 0.9
0.8


8 Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 66015 3.8 2.1
1.0
 0.2
 -0.4
 -0.2
 -0.2
 0.5
 -0.9
 1.4
 0.7
 -0.4
 3.2
 2.1




9 Zfp281 zinc finger protein 281 305083 3.8 2.4
 1.3
 0.9
 -0.1
 -0.3
 0.6
 -0.6
 -1.0
 2.0
 -0.4
 1.3
 -1.5
 0.1
 -1.1
 1.0
-0.0
 -0.1
-0.5


10 Nfkb1 nuclear factor kappa B subunit 1 81736 3.8 2.0
 1.6
 1.0
 -1.1
 0.6
 0.3
 -0.3
 0.7
 -0.2
 -0.2
 -0.2
 0.8
 -1.3
 1.9
 1.9
0.8
 0.6
0.3
 0.6

11 Rgs2 regulator of G-protein signaling 2 84583 3.8 1.7
 1.9
 2.6
 -0.3
 -0.8
 1.2
 0.3
 -0.2
 1.2
 0.5
 -1.9
 0.9
 0.4
 2.0
 2.7
0.9
 1.5
0.8
4.1
12 Tnfaip3 TNF alpha induced protein 3 683206 3.6 2.0
1.5
 -0.1
 -0.4
 -0.7
 -0.4
 0.2
 1.3
 0.1
 0.7
 -0.2
 0.5
 2.3
 1.3
 1.9


13 Crem cAMP responsive element modulator 25620 3.6 1.5
 2.1
 3.8
0.1
 -0.7
-1.2
 -0.5
-0.8
 0.3
-0.0
 0.0
-0.6
 -0.4
-1.0
 0.6
0.2
 -0.7
-0.9
 -0.5
-0.5
 0.5
0.3
 -0.5
-1.0
 0.5
-1.1
 2.5
0.4
 0.7
0.1
 0.7
-0.5
14 Zc3h12a zinc finger CCCH type containing 12A 313587 3.6 1.8
 1.7
 0.6
 0.3
 0.9
 0.3
 0.6
 0.9
 0.7
 1.2
 0.0
 0.2
 1.1
 1.2
 1.1
0.2
 1.3
0.7
 0.4

15 Wsb1 WD repeat and SOCS box-containing 1 303336 3.5 1.3
 2.1
 0.2
 -2.6
 0.2
 -0.3
 -0.6
 -1.1
 -0.8
 -1.2
 -2.5
 0.2
 0.4
 0.8
 1.9
 1.3


16 Map3k8 mitogen-activated protein kinase kinase kinase 8 116596 3.5 1.7
 1.7
 0.3
 -0.9
 0.8
 -1.0
 -0.7
 1.2
 -0.2
 0.3
 0.9
 -0.6
 -0.4
 3.0
 0.7
 0.8


17 Tlr2 toll-like receptor 2 310553 3.5 1.7
 1.6
 0.6
0.3
 -0.1
-0.8
 0.8
-0.6
 -0.5
-0.9
 -0.7
-0.8
 0.4
-0.4
 0.9
0.5
 -0.3
-0.4
 -0.8
 0.8
 0.7
-0.3
 1.2
0.3
 0.9
0.2
 1.2
0.0
 0.9
0.3

18 Nfkb2 nuclear factor kappa B subunit 2 309452 3.4 1.4
 1.9
 0.3
 0.1
 0.3
 0.0
 0.1
 1.0
 0.9
 1.5
 0.6
 0.3
 1.2
 -0.5
 0.9
 -0.5


19 Ednrb endothelin receptor type B 50672 3.4 1.4
 1.9
 1.4
 -0.7
 -0.6
 0.3
 -1.0
 0.3
 -0.9
 -0.4
 -0.8
 0.6
 0.4
 1.6
 0.9
 1.3


20 Pde10a phosphodiesterase 10A 63885 3.4 1.6
 1.7
 2.6
 0.2
 -0.4
 0.5
 0.1
 0.3
 0.1
 1.0
 0.7
 -0.3
 -0.1
 1.2
 0.7
 0.1


21 Cdyl2 chromodomain Y-like 2 292044 3.4 1.1
 2.2
 3.2
 1.5
 0.1
 1.3
 1.7
 0.7
 3.6
 1.5
 0.0
 -0.1
 -0.1
 0.5




22 Akap2 A-kinase anchoring protein 2 298024 3.4 1.9
 1.4
 2.1
 0.4





-0.6
 0.9






23 Cxcl1 C-X-C motif chemokine ligand 1 81503 3.3 1.0
 2.2
 1.1
0.6
 0.4
-0.5
 0.2
-0.1
 0.5
0.0
 -0.6
-0.7
 0.3
0.2
 1.7
1.5
 0.5
0.2
 0.2
0.1
 0.8
0.5
 -0.1
-0.7
 3.0
2.1
 2.3
-0.5
 0.3
-0.0

0.7
-1.1
24 Tnfaip6 TNF alpha induced protein 6 84397 3.3 0.9
 2.3
 1.5
 -0.8
 -1.0
 0.6
 -0.6
 0.2
 0.9
 0.3
 -1.5
 0.5
 -0.0
 1.5
 -0.4
 0.4


25 St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 304023 3.3 1.4
 1.8
 1.8
 0.7
 -0.2
 0.9
 -0.2
 -0.8
 0.1
 1.5
 -1.5
 -0.1
 0.4
 1.3




26 Tspyl4 TSPY-like 4 309828 3.2 1.6
 1.6
 1.9
 0.9
 0.3
 1.0
 -0.4
 -0.2
 0.7
 -0.1
 1.4
 0.3






27 Insyn2b inhibitory synaptic factor family member 2B 100361460 3.2 1.8
1.5
 0.9
 -1.3
 1.3
 -0.1
 0.7

-1.4
 0.6
 1.0
 0.4
 0.4
 0.4


28 Icam1 intercellular adhesion molecule 1 25464 3.2 1.4
 1.8
 -0.8
-1.2
 1.6
0.3
 0.7
0.6
 0.2
-0.8
 2.9
0.7
 4.8
3.1
 0.6
0.2
 0.8
0.6
 2.3
1.0
 2.3
1.7
 0.7
 0.7




29 Cflar CASP8 and FADD-like apoptosis regulator 117279 3.2 1.7
 1.4
 1.3
 -1.6







0.4
 0.3
 1.7
 -0.5


30 Skil SKI-like proto-oncogene 114208 3.2 1.8
0.8
 0.4
 -0.6
 0.1
 0.3
 0.5
 1.4
 0.7
 3.0
 0.5
 0.4
 2.4
 1.7
 -0.2


31 Etnk1 ethanolamine kinase 1 312828 3.2 1.8
 1.3
 4.0
-1.2
 0.3
-1.4
 2.3
1.1
 -0.2
-0.4
 0.3
-0.5
 0.4
-0.5
 1.7
 -0.2
 0.1
-0.1
 -1.3
-1.3
 3.3
-0.5
 1.0
-0.4
 0.9
0.8
 1.3
0.8
 0.8

32 Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 316395 3.1 1.2
 1.8
 1.8
 1.5


0.3
 1.3
 -0.1
 -1.8
 1.1
 -0.2
 0.6
 1.7
0.5
 1.1
0.6
 -0.2

33 RGD1563888 similar to DNA segment, Chr 16, ERATO Doi 472, expressed 360692 3.1 0.9
 2.2
 0.6
 -1.2
 -0.7
 0.1
 -0.5
 -2.2
 1.3
 -0.8
 -0.5
 -0.1
 -0.0
 2.0
 1.3
 0.7


34 Plat plasminogen activator, tissue type 25692 3.1 1.6
 1.4
 1.5
 -1.0
 -0.5
 0.3
 -1.5
 -0.1
 -0.6
 0.1
 -0.2
 -0.7
 -0.5
 -0.2
 0.6
 -0.4


35 Secisbp2l SECIS binding protein 2-like 296115 3.1 1.2
 1.8
 1.0
 0.0
 0.1
 0.4
 -1.0
 -0.0
 -0.0
 0.5
 -0.9
 -1.6

-0.8
 0.4


36 Nfkbiz NFKB inhibitor zeta 304005 3.1 1.8
 1.2
 0.8
-0.1
 -0.6
-0.8
 0.7
-0.3
 0.2
-0.7
 0.1
-1.0
 1.6
-0.6
 0.9
0.5
 1.9
-0.5
 1.3
0.8
 1.8
0.4
 1.4
1.3
 2.2
0.7
 1.6
0.6
 1.1
0.3
-0.2
37 Slc25a25 solute carrier family 25 member 25 246771 3.0 1.6
 1.3
 1.0
1.0
 1.7
0.8
 2.1
0.8
 0.2
-0.2
 1.0
0.8
 2.8
0.4
 0.2
-0.1
 1.2
-0.3
 1.1
0.4
 1.1
-0.6
 1.3
-1.5
 5.3
-1.5
 2.5
1.1
 0.3
0.2
 3.9
-0.5
-2.2
38 Zfp36l1 zinc finger protein 36, C3H type-like 1 29344 3.0 1.8
 1.1
 -0.4
-0.5
 -0.7
-0.8
 -0.5
-1.3
 0.5
-0.1
 0.3
-0.6
 0.9
0.3
 2.3
0.8
 1.1
0.5
 1.7
1.7
 1.6
0.6
 -0.0
-0.5
 2.2
-0.3
 1.4
1.1
 0.5
0.5
 2.9
 1.2
 -0.8
39 Gnb4 G protein subunit beta 4 294962 3.0 1.4
 1.6
 1.1
0.6
 0.8
0.6
 0.7
-0.0
 0.6
0.4
 1.2
0.5
 1.7
0.5
 0.4
0.1
 0.7
0.6
 0.4
0.2
 1.0
-0.0
 0.4
-0.2
 1.8
0.5
 1.1
0.9
 0.3
0.1
 5.9
1.5
 -0.2
40 Socs3 suppressor of cytokine signaling 3 89829 3.0 1.6
 1.4
 0.5
 -1.8
 -0.5
 -0.4
 -1.3
 0.5
 1.5
 -0.2
 0.8
 1.5
 -0.5
 2.5
 1.6
-0.2
 0.3
-0.3


41 Cxcl2 C-X-C motif chemokine ligand 2 114105 3.0 1.1
 1.8
 1.1
0.6
 0.4
-0.5
 0.2
-0.1
 0.5
0.0
 -0.6
-0.7
 0.3
0.2
 1.7
1.5
 0.5
0.2
 0.2
0.1
 0.8
0.5
 -0.1
-0.7
 3.0
2.1
 2.3
-0.5
 0.3
-0.0

0.7
-1.1
42 Bach2 BTB domain and CNC homolog 2 313125 3.0 1.7
2.9
 -1.2
 1.2
 1.6
 -0.9
 -0.3
 0.9
 -1.1
 0.1
 0.2
 0.5
 2.2
 2.4
 0.6


43 Dlg1 discs large MAGUK scaffold protein 1 25252 3.0 1.6
 1.2
 2.2
2.2
 2.3
0.5
 1.2
0.0
 1.3
0.8
 3.1
0.7
 4.7
0.6
 1.5
0.3
 0.7
0.2
 1.5
0.3
 0.3
0.2
 0.1
-0.4
 1.5
-0.4
 1.4
1.2
 1.4
1.1

0.7
0.4
44 Clcn4 chloride voltage-gated channel 4 60586 2.9 1.5
 1.3
 2.8
2.5
 1.4
-0.3
 0.4
-0.5
 0.3
 0.2
-1.9
 0.6
-0.6
 0.0
-0.2
 2.3
-0.9
 1.6
-0.1
 0.1
-1.0
 -0.0
-0.7
 0.9
0.6
 1.4
0.1
 0.3
0.2
 0.4
 0.8
45 Nr4a3 nuclear receptor subfamily 4, group A, member 3 58853 2.9 1.7
 1.2
 4.2
3.4
 2.3
0.9
 0.8
0.2
 2.6
1.7
 2.3
1.5
 2.2
2.0
 4.1
2.4
 2.6
1.8
 2.7
1.4
 1.6
1.0
 2.0
1.7
 5.9
4.9
 4.3
3.3
 0.3
-0.1
 1.8
-1.0
46 Nedd9 neural precursor cell expressed, developmentally down-regulated 9 291044 2.9 1.6
 1.2
 0.9
 -1.1
 0.1
 0.6
 -0.6
-0.1
 0.9
 1.1
 0.2
 -1.3
 0.1
 0.6
 0.4


47 Tspan2 tetraspanin 2 64521 2.9 1.7
 1.1
 1.0
-2.3
 -0.5
-0.6
 1.0
0.2
 1.0
-0.4
 0.7
0.3
 0.9
0.2
 2.4
0.4
 1.4
0.1
 0.7
0.6
 0.5
0.2
 0.8
0.7
 1.6
0.6
 1.6
1.5
 1.1
0.8

-0.2
-0.8
48 Dusp10 dual specificity phosphatase 10 63995 2.9 1.9
 0.9
 1.4
 0.1
 0.1
 0.9
 1.1
1.2
 2.6
 -0.1
 0.3
 0.4
 2.6
 1.0
-0.1
 -0.1
-0.5
 1.0

49 Arid5a AT-rich interaction domain 5A 316327 2.9 1.2
 1.6
 1.4
 -0.4
 -0.4
 0.9
 -0.8
 2.7
 1.5
 0.6
 1.2
 0.6
 1.0
 1.1
 0.5
0.1
 0.1
-0.8
0.0
 -0.7
50 Inpp4b inositol polyphosphate-4-phosphatase type II B 116699 2.9 1.1
 1.7
 3.7
0.3
 0.7
0.5
 0.7
-1.0
 1.7
-0.5
 0.4
-1.1
 1.4
-0.3
 1.2
1.0
 1.5
1.5
 -0.5
-1.2
 0.6
-1.0
 0.1
-0.2
 1.9
-0.3
 1.4
1.0
 1.7
0.6
 0.2

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