Orthologous genes in OrthoFinder**

Species Gene Description
 dme-u.3   Tpi   Triose phosphate isomerase 
 dme-r.4   Tpi   Triose phosphate isomerase 
 cel-u.3   tpi-1   Triosephosphate isomerase 
 hsa-u.4   TPI1   triosephosphate isomerase 1 
 mmu-u.4   Tpi1   triosephosphate isomerase 1 
 rno-u.3   Tpi1   triosephosphate isomerase 1 
 gga-u.3   TPI1   triosephosphate isomerase 1 
 dre-u.3   tpi1a   triosephosphate isomerase 1a 
 dre-u.3   tpi1b   triosephosphate isomerase 1b 
 mcc-u.3   TPI1   triosephosphate isomerase 1 
 cfa-u.3   TPI1   triosephosphate isomerase 1 
 sce-u.3   TPI1   triose-phosphate isomerase TPI1 

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Top 50 coexpressed genes to Tpi (dme-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dme1200   Carbon metabolism  20 117 6.36
 dme190   Oxidative phosphorylation  19 127 6.11
 dme10   Glycolysis / Gluconeogenesis  13 52 7.21
 dme1230   Biosynthesis of amino acids  12 64 6.66
 dme20   Citrate cycle (TCA cycle)  7 41 6.20

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dme:Tpi (Triose phosphate isomerase) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dme-u.3
for
Tpi
dme-r.4
for
Tpi
cel-u.3
for
tpi-1
hsa-u.4
for
TPI1
mmu-u.4
for
Tpi1
rno-u.3
for
Tpi1
gga-u.3
for
TPI1
dre-u.3
for
tpi1a
dre-u.3
for
tpi1b
mcc-u.3
for
TPI1
cfa-u.3
for
TPI1
sce-u.3
for
TPI1
1 Pglym78 Phosphoglyceromutase 78 43447 Dmel_CG1721 18.2 10.6
13.5
1.9
 15.1
2.2
 8.0
3.2
 13.6
2.8
 3.3
2.6
 6.9
3.5
 6.6
5.7
 9.5
2.6
 18.0
2 Eno Enolase 33351 Dmel_CG17654 16.1 9.4
 8.8
 14.1
7.2
 12.5
9.4
 8.6
4.6
 7.9
3.6
 4.2
3.7
 10.0
8.7
 7.3
2.3
 10.3
3.2
 13.6
9.4
3 Pgk Phosphoglycerate kinase 33461 Dmel_CG3127 14.6 8.5
 7.2
 16.5
 22.3
2.5
 17.9
-0.9
 14.2
 2.1
 13.0
 8.0
0.6
 12.9
 14.1
4 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1 35728 Dmel_CG12055 14.1 8.3
 4.9
4.4
 17.5
1.2
 15.1
3.9
 12.7
1.7
 17.6
0.9
 2.3
0.7
 5.9
4.8
 11.7
 14.0
 14.3
11.6
5 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2 32545 Dmel_CG8893 12.8 7.5
 4.9
4.4
 17.5
1.2
 15.1
3.9
 12.7
1.7
 17.6
0.9
 2.3
0.7
 5.9
4.8
 11.7
 14.0
 14.3
11.6
6 Pgi Phosphoglucose isomerase 35886 Dmel_CG8251 12.0 7.1
 5.9
 12.7
 16.3
 13.5
 10.9
 2.9
1.4
 8.0
2.6
 5.4
 10.5
 13.1
7 PyK Pyruvate kinase 42620 Dmel_CG7070 11.5 6.8
 5.3
1.3
 11.9
0.2
 15.8
0.4
 1.1
 8.8
 3.8
0.6
 5.6
3.4
 8.6
2.4
 7.1
0.1
 14.1
-0.6
8 Pfk Phosphofructokinase 36060 Dmel_CG4001 11.3 6.6
 6.6
-0.3
 6.6
5.5
 14.1
6.3
 5.2
5.2
 3.0
2.9
 2.5
2.1
 3.7
2.9
 3.2
2.8
 6.2
5.5
 8.2
7.4
9 AGBE 1,4-Alpha-Glucan Branching Enzyme 326264 Dmel_CG33138 9.8 5.7
 4.6
 6.2
 4.7
 3.6
 0.8
 0.8
 2.8
 3.2
 2.6
 -0.9
10 Ald1 Aldolase 1 43183 Dmel_CG6058 9.4 5.5
 5.3
2.1
 6.7
0.9
 18.7
5.6
 13.1
2.9
 5.2
1.5
 3.2
1.2
 8.0
5.0
 7.2
4.5
 12.9
4.6
11 Mdh1 Malate dehydrogenase 1 34414 Dmel_CG5362 8.4 4.9
 8.7
 3.4
 5.2
 4.7
 4.8
 3.5
3.0
 8.2
4.1
 3.8
 2.9
12 Gs1l GS1-like 33653 Dmel_CG15441 8.2 4.8
 2.1
 0.1

-0.3
 -0.3
 1.6
1.1
 0.2
13 Mdh2 Malate dehydrogenase 2 42185 Dmel_CG7998 8.1 4.8
 8.4
 1.6
 6.4
 6.0
 6.7
 3.7
 6.4
 6.3
 1.6
 1.3
14 UQCR-C2 Ubiquinol-cytochrome c reductase core protein 2 39846 Dmel_CG4169 8.0 4.7
 3.4
2.4
 2.5
 4.2
 3.6
 5.8
 2.4
1.3
 6.3
4.8
 4.1
 2.5
15 CG5903 uncharacterized protein 41959 Dmel_CG5903 7.8 4.6
 3.7
 1.7
0.1
 1.4
 4.6
1.3
 2.7
-0.4
 3.1
0.7
 3.6
0.8
 2.2
-0.9
 1.0
16 UQCR-C1 Ubiquinol-cytochrome c reductase core protein 1 41800 Dmel_CG3731 7.6 4.5
 2.6
 5.8
0.4
 4.9
2.5
 7.1
2.7
 5.5
1.9
 3.3
-0.1
 4.8
1.9
 7.6
1.6
 3.2
1.2
 -0.7
17 ATPsynF ATP synthase, subunit F 37931 Dmel_CG4692 7.5 4.4
 4.4
 4.5
 3.6
 4.6
 2.0
-0.7
 2.0
-1.5
 3.8
-1.0
 2.4
1.2

18 Got2 Glutamate oxaloacetate transaminase 2 33373 Dmel_CG4233 7.5 4.4
 4.2
1.0
 2.7
 4.9
 5.3
 6.3
 2.8
2.2
 6.6
4.4
 2.6
 1.2
19 Pdha Pyruvate dehydrogenase E1 alpha subunit 31406 Dmel_CG7010 7.3 4.3
 5.1
 3.0
 2.8
 3.6
 0.9
 1.7
0.4
 3.1
-0.3
 2.5
 3.2
 0.9
20 GlyP Glycogen phosphorylase 33386 Dmel_CG7254 7.2 4.2
 2.4
 1.8
1.3
 2.8
1.8
 2.3
1.6
 2.1
-0.3
 3.2
0.4
 3.8
2.8
 2.0
0.4
 0.7
0.4
 0.6
21 ND-18 NADH dehydrogenase (ubiquinone) 18 kDa subunit 32936 Dmel_CG12203 7.1 4.2
 4.1
 1.7
 3.1
 4.4
 1.6
 2.9
 3.6
 1.9
 3.2
22 levy levy 37728 Dmel_CG17280 7.1 4.2
 2.7
 3.5
1.2
 0.9
0.9
 3.2
1.0
 0.8
 2.3
2.1
 2.6
1.2
 0.8
 1.9
0.6
 -0.6
23 Pgm1 Phosphoglucose mutase 1 44010 Dmel_CG5165 7.0 4.1
 4.3
 6.1
-0.4
 13.0
-0.4
 8.1
-1.4
 5.6
-1.5
 1.1
 9.7
 3.6
-1.1
 3.8
-0.2
 1.1
0.1
24 Rpi Ribose-5-phosphate isomerase 246599 Dmel_CG30410 7.0 4.2
 2.8
 -0.8
 -0.7
 -0.5
 -0.6
 0.4
 -0.6
 -1.7
 0.1
 -0.7
25 RFeSP Rieske iron-sulfur protein 44390 Dmel_CG7361 7.0 4.1
 5.0
 3.1
 4.4
 5.9
 4.3
 1.7
 5.9
 2.5
0.4
 4.5
 -0.3
26 COX4 Cytochrome c oxidase subunit 4 35279 Dmel_CG10664 6.7 4.0
 3.4
 3.9
 2.3
2.2
 4.2
1.5
 5.4
 2.5
2.2
 5.4
5.3
 3.9
-0.2
 3.6
0.3
27 CG11752 uncharacterized protein 32076 Dmel_CG11752 6.7 4.0









28 ND-B17 NADH dehydrogenase (ubiquinone) B17 subunit 34925 Dmel_CG13240 6.7 4.0
 3.9








29 ATPsynE ATP synthase, subunit E 41745 Dmel_CG3321 6.7 4.0
2.9
 2.5
 2.8
 2.7
 2.7
2.1
 4.7
1.5
 2.5

30 Got1 Glutamate oxaloacetate transaminase 1 36782 Dmel_CG8430 6.7 3.9
 4.4
 1.4
 4.6
 4.2
 4.9
 1.6
 4.8
 4.6
 3.6
 0.7
31 GlyS Glycogen synthase 41823 Dmel_CG6904 6.6 3.9
 5.8
 6.7
 7.4
0.3
 6.3
0.5
 -0.1
 1.8
0.3
 4.2
-0.0
 2.1
-1.6
 5.6
 -0.3
-1.3
32 COX5A Cytochrome c oxidase subunit 5A 41432 Dmel_CG14724 6.6 3.9
 5.3
 3.0
 4.0
 5.5
 3.9
 2.4
1.9
 5.9
4.1
 3.3
 3.5
 0.0
33 ATPsyndelta ATP synthase, delta subunit 31950 Dmel_CG2968 6.6 3.9
 2.4
 1.3
 5.5
 6.2
 2.8
 2.1
 4.8
 3.6
 4.6
 -0.1
34 Vha13 Vacuolar H[+] ATPase 13kD subunit 42341 Dmel_CG6213 6.5 3.9
 3.2
 -0.3
-0.6
 1.4
0.1
 1.6
1.5
 4.4
1.6
 1.4
 4.1
 0.5
-1.8
 1.6
 0.2
35 ND-ACP NADH dehydrogenase (ubiquinone) acyl carrier protein 38154 Dmel_CG9160 6.5 3.9
 4.4
3.8
 3.4
 1.9
 5.6
 2.0
 2.3
0.8
 3.4
3.1
 1.9
 2.2
 -0.5
36 Taldo Transaldolase 37804 Dmel_CG2827 6.5 3.8
 3.0
 1.9
 0.1
 1.3
 3.1
 1.3
 1.7
 2.0
 2.8
 3.9
-0.3
37 ATPsyngamma ATP synthase, gamma subunit 43507 Dmel_CG7610 6.5 3.8
 7.2
 3.1
 4.2
 3.9
 5.3
 1.4
 5.5
 1.5
 3.2
 -0.1
38 NP15.6 NP15.6 42282 Dmel_CG6008 6.4 3.8
 4.1
 3.2
 1.8
 3.2
 1.9
 1.9
 3.1
 3.4
 5.0
39 Scsalpha1 Succinyl-coenzyme A synthetase alpha subunit 1 38447 Dmel_CG1065 6.3 3.8
 4.1
3.3
 2.6
 4.2
 4.5
 3.2
 2.0
 6.7
 3.9
 3.3
 -0.4
40 ND-B14.5A NADH dehydrogenase (ubiquinone) B14.5 A subunit 31190 Dmel_CG3621 6.3 3.7
 2.9
 2.3
2.7
 1.6
 2.9
 3.4
 3.6
 4.5
41 CG7430 uncharacterized protein 39988 Dmel_CG7430 6.3 3.7
 5.4
 1.4
 2.8
 3.2
 2.6
 1.9
 6.5
 1.5
 2.0
 0.4
42 blw bellwether 37617 Dmel_CG3612 6.2 3.7
 3.5
 3.5
 6.8
 5.7
 5.4
1.4
 4.0
 5.8
 4.2
 2.8
 -0.3
43 ND-B18 NADH dehydrogenase (ubiquinone) B18 subunit 32434 Dmel_CG5548 6.2 3.7
 4.7
 2.5
 2.2
 4.2
2.4
 3.4
 2.2
 3.4
44 CG7920 uncharacterized protein 43562 Dmel_CG7920 6.2 3.7
 4.9
2.4








45 Sod2 Superoxide dismutase 2 (Mn) 36878 Dmel_CG8905 6.1 3.6
 5.0
1.5
 1.2
 3.8
 4.5
 3.7
 3.4
 5.8
 1.2
 1.5
 0.4
46 Pdhb Pyruvate dehydrogenase E1 beta subunit 43437 Dmel_CG11876 6.1 3.6
 5.9
 2.0
 1.8
 3.3
 2.4
 2.3
 4.4
 2.1
 1.9
 0.8
47 ATPsynB ATP synthase, subunit B 39143 Dmel_CG8189 6.1 3.6
3.4
 4.5
 5.4
 5.2
 2.6
 5.1
 1.1
 1.1
48 ATPsynD ATP synthase, subunit D 42291 Dmel_CG6030 6.0 3.6
 6.3
 3.3
 3.2
 5.3
 3.5
 2.4
 4.0
 2.3
 2.2
 -0.3
49 CG5214 uncharacterized protein 41360 Dmel_CG5214 5.9 3.5
 4.9
 0.7
 2.7
 4.4
 2.6
 1.2
 4.6
 2.5
 1.6
 0.8
50 CG7322 uncharacterized protein 32880 Dmel_CG7322 5.9 3.5
 0.9
 0.9
 -0.1
-0.4
 -0.4
 1.0
 0.4
 0.7
 2.9
 2.4
0.1
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