Orthologous genes in OrthoFinder**

Species Gene Description
 dme-u.3   Hrs   Hepatocyte growth factor regulated tyrosine kinase substrate 
 dme-r.4   Hrs   Hepatocyte growth factor regulated tyrosine kinase substrate 
 dme-m.5   Hrs   Hepatocyte growth factor regulated tyrosine kinase substrate 
 cel-u.3   hgrs-1   Hepatocyte growth factor-regulated tyrosine kinase substrate 
 hsa-u.4   HGS   hepatocyte growth factor-regulated tyrosine kinase substrate 
 mmu-u.4   Hgs   HGF-regulated tyrosine kinase substrate 
 rno-u.3   Hgs   hepatocyte growth factor-regulated tyrosine kinase substrate 
 gga-u.3   HGS   hepatocyte growth factor-regulated tyrosine kinase substrate 
 dre-u.3   hgs   hepatocyte growth factor-regulated tyrosine kinase substrate 
 mcc-u.3   HGS   hepatocyte growth factor-regulated tyrosine kinase substrate 
 cfa-u.3   HGS   hepatocyte growth factor-regulated tyrosine kinase substrate 
 sce-u.3   VPS27   ESCRT-0 subunit protein VPS27 
 spo-u.3   SPAC25B8.17   peptidase family A22 

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Top 50 coexpressed genes to Hrs (dme-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 dme4144   Endocytosis  10 120 6.28
 dme4214   Apoptosis - fly  2 63 -
 dme4013   MAPK signaling pathway - fly  2 93 -
 dme4140   Autophagy - animal  2 100 -
 dme4142   Lysosome  2 122 -

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dme:Hrs (Hepatocyte growth factor regulated tyrosine kinase substrate) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

dme-u.3
for
Hrs
dme-r.4
for
Hrs
dme-m.5
for
Hrs
cel-u.3
for
hgrs-1
hsa-u.4
for
HGS
mmu-u.4
for
Hgs
rno-u.3
for
Hgs
gga-u.3
for
HGS
dre-u.3
for
hgs
mcc-u.3
for
HGS
cfa-u.3
for
HGS
sce-u.3
for
VPS27
spo-u.3
for
SPAC25B8.17
1 Stam Signal transducing adaptor molecule 34505 Dmel_CG6521 11.7 6.8
 4.8
 7.4
 2.2
1.6
 3.5
3.3
 5.5
2.4
 0.5
0.5
 3.0
1.9
 2.2
0.9
 1.5
1.0
 7.0
2 mop myopic 39610 Dmel_CG9311 8.3 5.0
 3.3
 3.5
 6.1
 6.3
 6.6
 5.2
 3.3
1.9
 5.0
 6.9
-0.1
3 Vta1 Vesicle trafficking 1 38204 Dmel_CG7967 6.3 3.9
 2.4
1.2
 2.1
 4.2
 -0.6
 1.2
 -0.6
 -0.5

4 Ist1 Ist1 38750 Dmel_CG10103 5.9 2.8
 3.0
 4.5
 1.3
 2.3
 2.3
 1.5
 1.8
 3.7
 -1.2
 3.2
 0.5
-1.4
5 CG11141 uncharacterized protein 35672 Dmel_CG11141 5.8 2.8
 2.9
0.9
 -0.3
 -0.6
 -0.7
 2.8
 1.0
 1.0

6 Vps4 Vacuolar protein sorting 4 32777 Dmel_CG6842 5.7 3.1
 2.6
 0.6
 3.3
2.2
 5.2
0.8
 4.0
0.8
 4.6
1.0
 2.7
1.8
 3.8
1.6
 2.3
-1.6
 -0.7
7 Ptpmeg2 Protein tyrosine phosphatase Meg2 31907 Dmel_CG32697 5.7 3.4
 2.3
 0.7
0.1
 -0.4
 0.8
 -0.4
 2.6
 3.3
0.1
 0.9
 0.0

8 Syx7 Syntaxin 7 36173 Dmel_CG5081 5.6 3.5
 2.1
 1.2
 1.0
0.1
 1.8
0.3
 2.1
-0.9
 1.0
-0.3
 3.5
1.4
 1.9
-0.1
 0.1
-0.5
2.4
9 CG3530 uncharacterized protein 37707 Dmel_CG3530 5.3 3.1
 2.2
 1.7
 0.7
0.5
 1.2
0.2
 1.5
-0.9
 0.4
0.4
 1.7
1.3
 1.1
0.2
 -0.2
-1.0
 0.2
10 CG7546 uncharacterized protein 38844 Dmel_CG7546 5.2 3.1
 2.2
3.6
 5.4
 5.9
 1.7
 3.4
3.1
 4.9
 7.9

11 c11.1 c11.1 53436 Dmel_CG12132 5.2 2.2
 3.0
 5.6
 4.2
 2.3
 2.2
 4.9
 -0.4
 2.2
 2.7
0.3
12 mv mauve 38259 Dmel_CG42863 5.2 2.4
 2.8

-1.0
 -0.9
 0.7
 3.2
 0.9
 0.0

13 Arpc1 Actin-related protein 2/3 complex, subunit 1 34793 Dmel_CG8978 5.2 2.7
 2.5
 2.1
 1.7
-0.2
 1.4
-0.0
 0.8
0.3
 1.4
1.3
 1.6
0.7
 1.5
-0.4
 1.2
-0.4
 1.1
 -0.7
14 puc puckered 40958 Dmel_CG7850 5.1 3.0


0.7
 -0.5
 -1.0
 0.2
-1.5
 -0.1
 -0.6

15 Scamp scamp 32470 Dmel_CG9195 5.0 2.5
 2.6
 1.0
 3.2
-1.4
 2.9
0.8
 3.6
 3.4
-0.2
 1.9
0.1
 1.9
-0.6
 2.2
-0.9

16 AP-1-2beta Adaptor Protein complex 1/2, beta subunit 32987 Dmel_CG12532 5.0 2.8
 2.3
 3.6
 2.6
0.9
 5.9
4.0
 3.4
2.8
 6.3
5.8
 3.3
0.6
 3.4
2.6
 1.9
1.6
 1.8
 0.6
17 CG3529 uncharacterized protein 39093 Dmel_CG3529 5.0 3.2
 1.8
 1.4
 4.2
2.1
 4.1
3.1
 3.6
1.2
 2.2
1.8
 2.0
0.6
 4.1
1.5
 4.0
0.8
 1.4
 -0.6
18 Vps39 Vacuolar protein sorting 39 42192 Dmel_CG7146 5.0 2.8
 2.2
 3.8
 1.4
 1.4
 2.6
 0.4
 3.2
 3.0
 2.5
 0.6
 -1.6
19 Atg4a Autophagy-related 4a 33283 Dmel_CG4428 4.9 2.7
 2.3
 1.0
 4.7
-1.3
 3.2
-0.9
 2.7
-2.0
 1.8
-2.1
 1.4
-0.1
 4.7
-1.7
 2.9
-1.4
 0.9
 1.3
20 ALiX ALG-2 interacting protein X 43330 Dmel_CG12876 4.9 2.9
5.5
 2.7
 4.1
 2.7
 1.8
 2.7
 3.3
 1.0
 2.6
2.2
 0.9
21 Cortactin cortactin 42491 Dmel_CG3637 4.9 2.7
 2.3
0.8
 -0.1
 -0.2
 0.9
 0.3
 1.5
 0.4

22 CG10435 uncharacterized protein 40948 Dmel_CG10435 4.9 3.4
 1.6









23 CHMP2B Charged multivesicular body protein 2b 38599 Dmel_CG4618 4.8 2.5
 2.3
 3.7
 -0.2
 2.0
 1.7
 -0.6
 1.0
 -0.1
 1.4
-0.1
24 Snx21 Sorting nexin 21 33466 Dmel_CG3077 4.8 2.7
 2.1
0.3
 0.3
-0.4
 1.6
-1.5
 -0.2
-0.7
 0.2
-2.3
 0.2
-0.8
 0.5
0.4
1.8
0.8
25 capt capulet 45233 Dmel_CG33979 4.8 2.5
 2.3
 0.8
0.2
 1.6
0.4
 0.7
-0.5
 0.7
0.0
 3.2
-0.1
 2.1
0.2
 2.6
-0.2
 1.7
-0.7
 0.8
 0.8
26 Vinc Vinculin 31201 Dmel_CG3299 4.8 2.3
 2.5
 -0.8
 -0.4
 0.3
 0.7
 -0.3
 2.1
0.2
 0.5
 0.7

27 CG17982 uncharacterized protein 31739 Dmel_CG17982 4.8 2.2
 2.6









28 CalpB Calpain-B 39165 Dmel_CG8107 4.8 2.3
 2.4
 1.0
0.8
 1.6
 1.3
 3.3
 2.4
0.3
 0.9
0.9
 -0.6
-0.7
 2.3
0.3

29 CG4557 uncharacterized protein 31629 Dmel_CG4557 4.7 2.5
 2.3
1.5
 0.3
 0.4
 0.6
 3.7
 0.8
 -0.5
0.4
30 SNF4Agamma SNF4/AMP-activated protein kinase gamma subunit 42515 Dmel_CG17299 4.7 2.4
 2.3
 -0.7
 0.7
0.2
 1.2
-1.0
 -0.4
-1.1
 4.7
-0.2
 1.0
-0.4
 0.3
0.1
 0.1
-0.4
 -1.6
 1.8
31 Faf2 Fas-associated factor 2 35129 Dmel_CG10372 4.7 3.1
 1.6
1.4
 2.9
 1.7
 1.3
 2.5
 2.3
 0.4
 1.3
 0.2
32 dor deep orange 31118 Dmel_CG3093 4.7 2.6
 2.1
 3.4
 3.1
 3.4
 2.7
 2.2
 0.1
 2.5
 2.4
 0.1
 1.7
33 CG17002 uncharacterized protein 35610 Dmel_CG17002 4.7 2.9
 1.8









34 Sec5 Secretory 5 33563 Dmel_CG8843 4.7 1.6
 3.0
 4.5
 0.4
 0.8
 1.3
 -0.3
 1.8
 1.1
 1.4
 0.4
35 sqh spaghetti squash 31554 Dmel_CG3595 4.6 2.5
 2.2
 2.0
-1.0
 0.3
0.1
 -0.3
-0.4
 2.2
0.9
 0.9
0.6
 0.2
-0.2
 0.1
-0.1
 1.6
1.2
0.5
-0.7
36 Trc8 TRC8 ring finger protein 43476 Dmel_CG2304 4.6 2.6
 2.1
-1.1
 -1.1
 1.1
 0.4
 2.2
 0.1
 -0.9

37 Mvb12 Multivesicular body subunit 12 32791 Dmel_CG7192 4.6 2.9
 1.8
 2.3
 -1.1
 -0.1
 0.7
 -0.5
 1.2
 -1.1
 1.4

38 Dnz1 DNZDHHC/NEW1 zinc finger protein 11 34503 Dmel_CG6627 4.6 3.0
 1.7
 -0.1


1.2
 -1.5



39 cathD cathepsin D 45268 Dmel_CG1548 4.6 2.1
 2.5
 0.7
0.6
 1.7
-0.0
 1.6
-0.0
 1.2
1.1
 2.9
0.9
 1.2
0.4
 2.0
0.2
 1.1
1.1
 2.2
1.7
40 Snx6 Sorting nexin 6 34126 Dmel_CG8282 4.6 2.7
 2.0
 2.0
 0.7
 1.2
0.3
 1.6
-0.5
 -0.9
 0.2
 -0.3
-0.6
 0.8
-0.7

41 CDC50 CDC50 32615 Dmel_CG9947 4.6 2.8
 1.8
 1.9
-0.1
 -0.1
-0.5
 0.7
0.4
 1.0
-0.9
 0.1
-0.3
 2.6
0.6
 0.6
0.0
 0.4
-0.4
 0.8
-0.8
42 CG17565 uncharacterized protein 41989 Dmel_CG17565 4.6 2.5
 2.1
 1.1
2.9
 2.4
 1.6
 -2.2
 1.8
 1.1
 0.0
43 Tab2 TAK1-associated binding protein 2 37216 Dmel_CG7417 4.6 2.2
 2.4









44 red red Malpighian tubules 41738 Dmel_CG12207 4.6 3.3
 1.3
 2.0
 0.4
-0.9
 2.0
0.1
 -0.3
-0.7
 1.0
0.1
 -0.2
-1.2
 2.0
-0.2
 0.5
-0.3

45 CG4080 uncharacterized protein 39079 Dmel_CG4080 4.6 2.9
 1.7
-0.6
 -0.2
 -0.9
 0.1
 -1.1
 0.2
 0.7

46 tamo tamo 37864 Dmel_CG4057 4.5 3.3
 1.3
1.6
 1.7
 1.9
 0.3
 3.9
1.5
 2.1
 3.4

47 Sep2 Septin 2 42438 Dmel_CG4173 4.5 2.1
 2.4
 1.3
 0.2
-0.9
 0.4
-0.3
 0.7
0.3
 0.6
0.3
 1.5
1.1
 -0.5
-0.8
 0.5
-0.1
1.2
48 DNApol-iota DNA polymerase iota 40965 Dmel_CG7602 4.5 1.8
 2.7
0.7
 -0.3
 -0.5
-0.3
 0.3
 0.1

49 Khc Kinesin heavy chain 36810 Dmel_CG7765 4.5 2.4
 2.1
 4.8
 0.6
0.2
 0.7
0.3
 1.2
1.0
 2.5
0.2
 2.6
1.9
 0.7
0.4
 1.0
0.7
1.3
-0.3
50 Ptpmeg Protein tyrosine phosphatase Meg 38059 Dmel_CG1228 4.5 3.4
 1.2
 -1.0
 -3.1
 -1.2
 -0.6
 -0.1
 3.5
-0.5
 -1.4
 -0.8

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