Orthologous genes in OrthoFinder**

Species Gene Description
 sce-u.3   ESP1   separase 
 sce-r.3   ESP1   separase 
 sce-m.4   ESP1   separase 
 spo-u.3   SPBC4B4.01c   putative Fbl-like pantothenate kinase 
 hsa-u.4   ESPL1   extra spindle pole bodies like 1, separase 
 mmu-u.4   Espl1   extra spindle pole bodies 1, separase 
 rno-u.3   Espl1   extra spindle pole bodies like 1, separase 
 gga-u.3   ESPL1   extra spindle pole bodies like 1, separase 
 dre-u.3   espl1   extra spindle pole bodies like 1, separase 
 dme-u.3   Sse   Separase 
 cel-u.3   ZK430.5   Peptidase C50 domain-containing protein 
 cel-u.3   sep-1   Separin homolog sep-1 
 mcc-u.3   ESPL1   extra spindle pole bodies like 1, separase 
 cfa-u.3   ESPL1   extra spindle pole bodies like 1, separase 

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Top 50 coexpressed genes to ESP1 (sce-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 sce4111   Cell cycle - yeast  8 129 4.88
 sce4113   Meiosis - yeast  5 127 2.32
 sce4145   Phagosome  2 35 -
 sce3013   Nucleocytoplasmic transport  2 65 -
 sce4011   MAPK signaling pathway - yeast  2 114 -

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sce:ESP1 (separase) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

sce-u.3
for
ESP1
sce-r.3
for
ESP1
sce-m.4
for
ESP1
spo-u.3
for
SPBC4B4.01c
hsa-u.4
for
ESPL1
mmu-u.4
for
Espl1
rno-u.3
for
Espl1
gga-u.3
for
ESPL1
dre-u.3
for
espl1
dme-u.3
for
Sse
cel-u.3
for
ZK430.5
cel-u.3
for
sep-1
mcc-u.3
for
ESPL1
cfa-u.3
for
ESPL1
1 SPC98 Spc98p 855597 YNL126W 9.7 5.5
 3.8
1.3
 0.6
 0.2
 0.7
 3.5
 4.3

0.9
 0.2
2 YCS4 condensin subunit YCS4 850977 YLR272C 8.8 5.7
 2.8
 -1.2
 5.1
 7.8
 5.7
 6.0
 11.2
 4.5
 1.5
 2.1
 5.9
 7.5
3 GEA1 Arf family guanine nucleotide exchange factor GEA1 853488 YJR031C 8.6 4.8
1.8
 1.5
 1.4
 0.1
 1.8
 1.3
 -0.1
 0.0
 1.9
 0.7
 1.0
4 TEL2 Tel2p 852991 YGR099W 8.0 4.2
 3.5
2.5
 0.9
 -1.1
 -0.5
 0.1
-0.6
 1.0
 0.9
 1.6
5 LTE1 mitotic regulator LTE1 851209 YAL024C 6.9 4.0
 2.7










6 STU1 Stu1p 852246 YBL034C 6.8 3.9
 2.6
 -1.1









7 YCG1 condensin subunit YCG1 851925 YDR325W 6.7 3.7
 2.8
5.8
 8.2
 5.7
 8.3
 10.2
 1.4

4.7
 7.1
8 SRS2 DNA helicase SRS2 853353 YJL092W 6.5 3.5
 2.8
 1.9









9 APC1 anaphase promoting complex subunit 1 855549 YNL172W 6.1 3.4
-1.3
 0.0
 1.2
 1.2
 2.1
 3.7
 2.7
 1.7
 5.3
 0.7
 2.7
10 HIR3 Hir3p 853605 YJR140C 6.0 3.6
 2.3
 -0.3









11 BUB1 protein kinase BUB1 853100 YGR188C 6.0 3.3
 2.5
 -0.4
 6.1
 9.9
 8.2
 5.4
 9.3
 5.1
-0.9
 1.4
 6.4
 6.2
 7.3
12 KAR3 Kar3p 856263 YPR141C 6.0 2.8
 3.0
11.0
5.4
 9.5
8.6
 7.8
7.5
 6.6
3.6
 9.3
9.1
 3.3
3.0
 0.2
-0.3
 7.6
5.7
 6.3
4.2
 6.5
2.4
13 BUD3 Bud3p 850345 YCL014W 5.9 3.2
 2.5










14 KIP1 Kip1p 852216 YBL063W 5.9 3.3
 2.4
6.3
 9.9
 6.8
 5.1
 9.0
 4.9
 2.0
 5.8
 5.6
 6.3
15 DYN1 dynein heavy chain 853928 YKR054C 5.9 3.2
 2.5
 0.1
 0.2
 1.1
 0.3
 0.4
 2.0
 -1.0
 0.8
 3.3
 0.1
 0.5
16 SPC97 Spc97p 856577 YHR172W 5.9 2.9
 2.7
0.2
 0.5
 1.7
 -0.6
 1.1
 1.3
-1.0

-0.3
17 CIN8 kinesin motor protein CIN8 856648 YEL061C 5.7 3.5
 2.1
11.0
5.4
 9.5
8.6
 7.8
7.5
 6.6
3.6
 9.3
9.1
 3.3
3.0
 0.2
-0.3
 7.6
5.7
 6.3
4.2
 6.5
2.4
18 MDM1 Mdm1p 854867 YML104C 5.7 3.0
 2.5
-0.4
 0.2
 -0.3
 0.1
 -1.3
 0.6

-1.9
 -0.3
19 CBF2 Cbf2p 853041 YGR140W 5.6 2.8
 2.6










20 LAA1 Laa1p 853223 YJL207C 5.3 3.1
 2.0
 -0.4
 0.3
-0.0
 1.9
0.8
 0.5
-0.6
 0.9
-0.9
 3.4
1.5
 0.2
 1.1
 2.7
 2.2
0.3
 1.0
0.1
21 SPC105 Spc105p 852787 YGL093W 5.2 2.3
 2.7
 -0.1









22 SGO1 Sgo1p 854240 YOR073W 5.1 2.7
 2.3










23 SGS1 ATP-dependent DNA helicase SGS1 855228 YMR190C 5.1 2.6
 2.4
3.9
0.5
 3.7
1.2
 3.1
0.1
 4.6
0.1
 4.7
0.3
 2.4
 0.6
0.4
 7.2
1.2
 0.1
0.0
 2.2
1.0
24 GAS3 putative 1,3-beta-glucanosyltransferase 855255 YMR215W 5.1 2.1
 2.8










25 IQG1 Iqg1p 855834 YPL242C 5.1 3.1
 1.8
 0.0
 10.8
0.2
 12.8
0.3
 8.5
0.1
 9.2
1.1
 7.8
2.3
-0.4
 1.1
 5.3
1.5
 3.9
0.6
26 PAN2 poly(A)-specific ribonuclease 852786 YGL094C 5.0 2.9
 2.0
 -0.4
 2.1
 1.7
 0.8
 2.0
 1.7
 -0.2
 1.2
 3.1
 1.7
 1.3
27 FKH1 forkhead family transcription factor FKH1 854675 YIL131C 5.0 2.5
 2.4
0.4
0.3
 0.4
0.4
 0.1
0.0
 1.4
0.6
 0.9
0.9
 1.2
0.0
 1.4
1.3
 0.2
-0.1
 -0.4
-1.0
 0.6
0.6
28 ORC1 origin recognition complex subunit 1 854937 YML065W 4.9 2.5
 2.3
6.0
 4.4
 4.1
 3.7
 4.6
 3.3
 0.2
 5.3
 3.2
 3.7
29 STU2 Stu2p 850734 YLR045C 4.9 2.2
 2.6
2.7
 4.0
 2.0
 3.3
 6.6
 1.3
 0.4
-0.4
 6.1
1.9
 3.1
 3.3
30 YLL032C uncharacterized protein 850627 YLL032C 4.8 2.8
 1.9
 0.2









31 VPS15 ubiquitin-binding serine/threonine protein kinase VPS15 852394 YBR097W 4.8 2.7

0.9
 0.8
 0.0
 -0.5
 1.2
 -0.3
 -0.1
 3.3
 0.0
 0.8
32 FIR1 Fir1p 856754 YER032W 4.8 2.8
 1.9










33 SET1 histone methyltransferase SET1 856519 YHR119W 4.8 2.6
 2.0
 0.1
 0.7
0.4
 1.4
0.1
 -0.1
-0.3
 2.6
1.2
 1.4
0.1
 0.4
 1.0
 2.6
 1.3
0.9
 1.3
0.2
34 FAB1 1-phosphatidylinositol-3-phosphate 5-kinase 850574 YFR019W 4.8 2.7
1.4
 0.3
 -0.7
 -0.6
 -0.9
 0.4


-0.3
 0.8
35 BEM2 GTPase-activating protein BEM2 856899 YER155C 4.7 2.7
 1.9










36 DNF1 aminophospholipid-translocating P4-type ATPase DNF1 856913 YER166W 4.7 2.2
 2.3
0.8
0.2
 0.6
0.6
 1.1
0.8
 2.1
1.1
 2.6
2.2
 1.4
0.7
 0.7
0.3
 3.0
1.9
 0.7
0.6
 1.1
0.8
37 RIF1 DNA-binding protein RIF1 852578 YBR275C 4.7 2.6











38 YGL176C uncharacterized protein 852699 YGL176C 4.6 2.6











39 SSK2 mitogen-activated protein kinase kinase kinase SSK2 855765 YNR031C 4.6 1.8
 2.6
0.1
 1.1
 0.5
 -1.1
 3.2
 -0.6

-0.6
 0.5
40 SLH1 putative RNA helicase 853187 YGR271W 4.5 2.6
-1.8
 1.8
-1.2
 1.4
-0.3
 0.2
-0.5
 2.2
0.1
 2.6
1.8
 0.5
0.1
 0.8
-0.6
 3.4
0.8
 1.4
 2.0
-0.4
41 VIK1 Vik1p 855822 YPL253C 4.4 2.5











42 SPP382 mRNA splicing protein SPP382 851143 YLR424W 4.4 1.8
 2.5
 0.8
 1.2
 0.4
 -0.4
 -0.1
 1.8
 -2.0
 1.0
 0.3
 0.4
 -0.0
43 MYO1 myosin 1 856418 YHR023W 4.4 2.6
 1.6
 1.4
0.6
 0.6
0.5
 1.1
0.5
 1.0
0.8
 0.9
0.7
 2.6
2.3
 -0.4
-0.5
 0.4
0.2
 3.6
2.3
 1.5
1.3
 1.7
1.6
44 CSF1 Csf1p 850776 YLR087C 4.4 2.8
 1.5
0.4
 -0.2
 -0.3
 1.4
 2.2
 -0.5
 0.8
 2.5
 0.2
 -0.8
45 TOF2 Tof2p 853880 YKR010C 4.3 2.5











46 VID22 Vid22p 851088 YLR373C 4.3 2.4
 1.8










47 NUP157 Nup157p 856842 YER105C 4.3 2.4
0.9
 1.1
 2.4
 2.0
 2.3
 4.6
 2.7

0.7
 1.3
48 SMC4 condensin subunit SMC4 850775 YLR086W 4.3 2.0
 2.1
3.0
 3.3
 3.5
 4.6
 12.1
 4.0
 1.7
1.2
 4.2
1.3
 2.8
 3.9
49 NUP192 Nup192p 853410 YJL039C 4.2 2.5
 1.6
 2.2
 1.7
 3.2
 2.0
 3.9
 2.6
 -0.1
 0.9
 4.6
 1.0
 1.7
50 CLB4 B-type cyclin CLB4 850907 YLR210W












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