Orthologous genes in OrthoFinder**

Species Gene Description
 sce-u.3   NRG2   Nrg2p 
 sce-r.3   NRG2   Nrg2p 
 sce-m.4   NRG2   Nrg2p 
 sce-u.3   NRG1   transcriptional regulator NRG1 
 hsa-u.4   ZBTB25   zinc finger and BTB domain containing 25 
 hsa-u.4   ZBTB2   zinc finger and BTB domain containing 2 
 mmu-u.4   Zbtb25   zinc finger and BTB domain containing 25 
 mmu-u.4   Zbtb2   zinc finger and BTB domain containing 2 
 rno-u.3   Zbtb25   zinc finger and BTB domain containing 25 
 rno-u.3   Zbtb2   zinc finger and BTB domain containing 2 
 gga-u.3   ZBTB25   zinc finger and BTB domain containing 25 
 gga-u.3   ZBTB2   zinc finger and BTB domain containing 2 
 dre-u.3   zbtb25   zinc finger and BTB domain containing 25 
 dre-u.3   zbtb2a   zinc finger and BTB domain containing 2a 
 dre-u.3   zbtb2b   zinc finger and BTB domain containing 2b 
 mcc-u.3   ZBTB25   zinc finger and BTB domain containing 25 
 mcc-u.3   ZBTB2   zinc finger and BTB domain containing 2 
 cfa-u.3   ZBTB2   zinc finger and BTB domain containing 2 
 cfa-u.3   ZBTB25   zinc finger and BTB domain containing 25 

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Top 50 coexpressed genes to NRG2 (sce-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 sce100   Steroid biosynthesis  7 18 6.48
 sce515   Mannose type O-glycan biosynthesis  1 7 -
 sce514   Other types of O-glycan biosynthesis  1 14 -
 sce670   One carbon pool by folate  1 15 -
 sce4141   Protein processing in endoplasmic reticulum  2 93 -

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sce:NRG2 (Nrg2p) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

sce-u.3
for
NRG2
sce-r.3
for
NRG2
sce-m.4
for
NRG2
sce-u.3
for
NRG1
hsa-u.4
for
ZBTB25
hsa-u.4
for
ZBTB2
mmu-u.4
for
Zbtb25
mmu-u.4
for
Zbtb2
rno-u.3
for
Zbtb25
rno-u.3
for
Zbtb2
gga-u.3
for
ZBTB25
gga-u.3
for
ZBTB2
dre-u.3
for
zbtb25
dre-u.3
for
zbtb2a
dre-u.3
for
zbtb2b
mcc-u.3
for
ZBTB25
mcc-u.3
for
ZBTB2
cfa-u.3
for
ZBTB2
cfa-u.3
for
ZBTB25
1 UPC2 Upc2p 851799 YDR213W 4.7 2.5
 2.1















2 HAP1 Hap1p 850958 YLR256W 4.4 2.0
 2.3















3 ERG3 C-5 sterol desaturase 850745 YLR056W 4.4 2.2
 2.1
 0.2
 0.2
 -0.5
 -0.4
 -0.5
 0.3
 -0.8
 0.1
 -1.8
 -0.5
 -0.5
 -1.2
 0.1
 -2.2
 0.4
 0.5
4 PRM4 pheromone-regulated protein PRM4 855947 YPL156C 4.4 2.0
 2.2















5 NEM1 Nem1-Spo7 phosphatase catalytic subunit NEM1 856393 YHR004C 4.0 2.0
 2.0
 0.2
 0.9
 1.9
 1.2
 0.4
 -0.4
 1.4

0.6
0.1
 0.0
-0.7
 1.1
0.7
 -0.3
 0.7
 1.8
 -1.3
6 ROX3 Rox3p 852184 YBL093C 4.0 2.2
 1.7
 1.1














7 PBI1 Pbi1p 855856 YPL272C 4.0 1.9
 2.0















8 NRG1 transcriptional regulator NRG1 851613 YDR043C 3.9 1.6
 2.1
 3.9
 1.3
 1.3
 0.3
 0.3
 -0.6
 -0.6
 -2.0
 -2.0
 -0.4
-1.0
 3.5
-1.0
 3.5
-0.4
 -0.2
 -0.2
 -0.1
 -0.1
9 ERG25 methylsterol monooxygenase 852951 YGR060W 3.9 1.8
 2.0
 -0.4
 0.4
 -0.7
 -0.9
 -1.4
 -0.5
 -0.9
 -0.8
 -0.7
 -0.1
 -0.4
 -1.4
 -1.0
 0.6
 -1.6
-1.7
 -0.1
-0.2
10 HES1 oxysterol-binding protein related protein HES1 854412 YOR237W 3.8 2.0
 1.7
 -0.6
-0.8














11 DAP1 Dap1p 855933 YPL170W 3.7 1.9
 1.7
 -0.2
 1.4
-1.5
 0.5
0.4
 -0.2
-0.5
 0.6
0.0
 0.5
-1.3
 0.3
-0.1
 0.1
-0.4
 1.7
-0.6
 0.2
-1.1
 -0.4
-0.7
 0.7
-0.5
 0.7
-1.0
 1.0
-0.3
 1.4
0.8
 0.4
-0.2
12 FHN1 Fhn1p 853032 YGR131W 3.4 1.1
 2.1
 0.4
-0.5














13 YPR145C-A uncharacterized protein 3799978 YPR145C-A 3.3 1.9
















14 ADD37 Add37p 855222 YMR184W 3.3 1.8
 1.5















15 SET4 Set4p 853339 YJL105W 3.2 1.8
1.2
0.1
 0.6
-0.7
 0.6
-0.6
 3.4
-1.0
 0.9
0.9
 3.3
0.7
 0.7
0.6
 -1.2
-1.6
 2.5
1.7
 1.5
1.4
 -0.3
-0.8
 0.2
-0.9
 1.2
0.6
 1.5
-0.7
 0.7
0.4
 1.5
0.3
16 TOS3 serine/threonine protein kinase TOS3 852696 YGL179C 3.2 1.8
0.3
-0.2
 0.2
-1.2
 0.6
-0.6
 1.0
-0.1
 0.5
-1.5
 -0.3
-0.5
 0.6
0.4
 1.0
-0.9
 1.0
0.7
 0.4
0.3
 1.2
-0.2
 1.2
0.7
 0.9
-1.7
 0.2
-0.2
 0.9
0.8
 -0.2
-0.8
17 ERG11 sterol 14-demethylase 856398 YHR007C 3.1 1.7
 1.4
 -0.2
 -0.8
 0.5
 -1.1
 -0.4
 -0.5
 -0.4

-0.2
 -1.9
 -0.2
 -1.5
 -0.2
 -0.3
 -0.8
18 ECL1 Ecl1p 853049 YGR146C 3.1 1.8
















19 ICT1 lysophosphatidic acid acyltransferase ICT1 850788 YLR099C 3.1 1.0
 2.0
 1.3
0.9
 1.1
-0.6
 1.1
0.7
 0.3
-1.0
 -0.0
-0.6
 0.4
-2.4
 0.0
-1.4
 -0.1
 -0.0
 2.0
1.0
 0.3
-0.0
 1.6
0.9
 0.3
-0.9
 0.6
0.0
 1.3
1.0
 1.0
-0.1
20 TYE7 Tye7p 854525 YOR344C 3.0 1.7
 1.3
 2.2
1.7
 0.8
0.7
 0.4
-0.1
 1.9
-0.5
 -0.7
-0.8
 0.6
-0.4
 0.6
-0.1
 0.4
-0.5
 -0.1
-0.4
 0.2
-0.5
 0.2
-0.6
 0.5
-0.2
 0.3
-1.2
 -0.4
-1.1
 1.7
 1.1
21 SPO73 Spo73p 856770 YER046W 3.0 1.2
 1.8
 0.5
 -0.8
 -2.4
 -0.2
 0.5
 1.4
 0.4
 0.4
 -1.2
 1.0
0.8
 -0.6
-1.4
 0.3
-0.0
 0.2
 -0.9
 0.5
 -0.5
22 YOR062C uncharacterized protein 854228 YOR062C 2.9 1.4
 1.5















23 ATF2 alcohol O-acetyltransferase 853088 YGR177C 2.9 1.4
 1.5















24 SND1 Snd1p 851767 YDR186C 2.9 1.0
 1.8















25 DFR1 dihydrofolate reductase 854411 YOR236W 2.9 1.6
 1.3
 -0.1
 0.9
-1.0
 -0.2
-1.0
 -0.1
 1.2
 -0.3
 0.3
 -1.1
 -0.2
 1.4
0.3
 -0.0
-1.7
 -0.1
-0.5
 0.8
0.5
 1.3
1.1
 -0.3
-1.0
 0.7
-0.1
26 TIP1 putative lipase 852359 YBR067C 2.9 1.9
 1.0















27 OPY1 Opy1p 852426 YBR129C 2.8 1.5
 1.3















28 ERG6 sterol 24-C-methyltransferase 855003 YML008C 2.8 2.1
 0.7
 -1.0














29 ERG1 squalene monooxygenase 853086 YGR175C 2.7 1.6
 1.1
 0.1
 -0.6
 0.3
 0.4
 -1.5
 -0.4
 -0.3
 -0.7
 -0.6
 0.7
 0.2
 0.2
 -1.6
 -0.7
 -1.2
 -0.8
30 NCP1 NADPH--hemoprotein reductase 856438 YHR042W 2.7 1.4
 1.2
 -2.0
 -1.4
 -0.4
 -0.7
 1.1
 -2.3
 -0.1
 1.9
 -0.2
 0.1
-0.5
 -0.2
-0.6
 0.6
-1.0
 -0.8
 1.0
 -0.1
 -0.9
31 GYP8 GTPase-activating protein GYP8 850517 YFL027C 2.6 1.1
 1.5
 0.5
 0.5
 0.6
 -0.6
 2.4
 0.2
 2.3
 1.1
 1.3
 2.1
-0.7
 0.1
-1.6
 0.1
-0.5
 -0.2
 1.3
 2.1
 -0.8
32 ERG5 C-22 sterol desaturase 855029 YMR015C 2.6 1.3
 1.3
 0.3
 0.7
0.3
 -1.1
-1.5
 -0.1
-0.1
 0.0
-0.1
 2.0
0.8
 0.0
-0.1
 -0.2
-0.9
 -0.2
-0.5
 0.7
0.1
 1.5
1.4
 0.7
0.6
 1.2
0.5
 0.0
-0.6
 0.7
 -1.2
33 EGH1 hydrolase 854824 YIR007W 2.6 1.6
 1.0















34 GPA1 guanine nucleotide-binding protein subunit alpha 856394 YHR005C 2.6 0.9
 1.6
 1.9
1.3
 1.0
-0.1
 0.8
0.7
 0.6
0.5
 1.7
0.9
 0.5
0.1
 1.8
1.6
 0.7
0.1
 1.5
0.8
 3.1
0.8
 1.5
1.4
 2.2
1.6
 1.4
1.4
 0.7
0.5
 2.6
2.2
 1.0
0.5
35 YSY6 Ysy6p 852460 YBR162W-A 2.6 1.5
















36 VPS36 ESCRT-II subunit protein VPS36 851135 YLR417W 2.6 1.2
 1.3
 1.9
 -0.5
 -0.6
 -0.0
 0.5
 0.5
 -0.5
 0.7
 3.2
 0.6
 -1.2
 -1.6
 0.3
 -0.2
 0.0
 0.6
37 PIG2 putative protein phosphatase regulator PIG2 854766 YIL045W 2.5 1.0
 1.5
 1.5
1.2
 1.8
1.4
 1.6
-0.3
 -0.5
-1.1
 -1.2
-1.7
 0.2
-0.4
 -0.2
-1.2
 3.1
2.0
 0.9
0.3
 0.2
-0.2
 2.3
0.8
 2.2
1.1
 1.6
-0.1
 0.1
-0.4
 -0.7
-0.8
 0.1
-0.4
38 ERG24 delta(14)-sterol reductase 855441 YNL280C 2.5 1.6
 0.9
 -1.3
-1.8
 -0.3
-0.5
 1.4
0.0
 0.8
0.1
 1.4
-1.1
 0.3
-0.1
 1.1
-0.8
 -0.5
-0.5
 3.1
-0.7
 1.4
0.6
 0.8
0.1
 2.5
0.8
 2.2
-0.3
 0.8
0.3
 1.7
-0.4
 0.8
0.1
39 RTS3 Rts3p 853065 YGR161C 2.5 1.5
















40 IZH4 Izh4p 854052 YOL101C 2.5 1.5
















41 ICS2 Ics2p 852454 YBR157C 2.5 1.5
















42 IGO1 phosphatase regulator 855565 YNL157W 2.5 1.5
1.7
-0.7
 0.0
-1.0
 1.1
-0.4
 -0.2
-1.4
 0.2
-0.0
 1.3
-0.6
 -0.6
-1.5
 0.7
-1.3
 1.7
0.7
 0.8
0.5
 -0.9
-1.0
 -0.3
-0.9
 -0.3
-1.1
 2.0
0.3
 0.8
-0.7
 0.4
-0.0
43 YNL208W uncharacterized protein 855513 YNL208W 2.5 1.4
















44 PMT3 dolichyl-phosphate-mannose-protein mannosyltransferase PMT3 854499 YOR321W 2.5 1.4
0.2
-0.4
 0.8
 -0.1
 0.3
 -0.1
 1.5
 -0.9
 0.6
 -1.4
 1.1
 -0.5
 -0.1
 -1.1
 -0.6
 0.4
 -0.5
45 DER1 derlin 852500 YBR201W 2.5 1.4
0.6
-0.3
 -0.2
-0.5
 1.7
1.5
 -0.7
-0.8
 0.8
-0.0
 0.3
0.1
 0.1
-1.0
 2.2
0.2
 1.9
0.8
 -0.6
-0.7
 1.4
-0.1
 1.7
1.1
 0.5
0.3
 3.0
1.7
 0.3
-0.1
 -0.7
-0.9
46 SCM4 Scm4p 852940 YGR049W 2.5 1.4
















47 EUG1 protein disulfide isomerase EUG1 852130 YDR518W 2.4 1.4
-1.3
-2.0
 -0.3
-0.6
 -0.4
-0.5
 -0.1
-1.3
 -0.2
-0.9
 -0.1
-1.8
 -0.8
-1.9
 0.9
0.6
 0.4
-0.4
 2.3
-0.5
 0.6
0.0
 1.7
0.3
 -0.7
-1.3
 1.4
-0.4
 0.6
-0.4
 0.8
-0.6
48 MRL1 Mrl1p 856194 YPR079W 2.4 1.3
 1.1
 3.3
-0.4
 -1.1
 0.7
 -1.5
 0.2
 0.6
 -0.1
 -1.0
 1.3
 -0.7
 1.5
 1.0
 -0.3
 0.0
 0.1
 -0.3
49 YBR085C-A uncharacterized protein 852381 YBR085C-A 2.4 1.3
 1.0















50 RHO2 Rho family GTPase RHO2 855634 YNL090W 2.4 1.1
 1.3
 -0.2














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