Orthologous genes in OrthoFinder**

Species Gene Description
 sce-u.3   TPD3   protein phosphatase 2A structural subunit TPD3 
 sce-r.3   TPD3   protein phosphatase 2A structural subunit TPD3 
 sce-m.4   TPD3   protein phosphatase 2A structural subunit TPD3 
 hsa-u.4   PPP2R1B   protein phosphatase 2 scaffold subunit Abeta 
 hsa-u.4   PPP2R1A   protein phosphatase 2 scaffold subunit Aalpha 
 mmu-u.4   Ppp2r1b   protein phosphatase 2, regulatory subunit A, beta 
 mmu-u.4   Ppp2r1a   protein phosphatase 2, regulatory subunit A, alpha 
 rno-u.3   Ppp2r1b   protein phosphatase 2 scaffold subunit A beta 
 rno-u.3   Ppp2r1a   protein phosphatase 2 scaffold subunit A alpha 
 dre-u.3   ppp2r1bb   protein phosphatase 2, regulatory subunit A, beta b 
 dre-u.3   ppp2r1ba   protein phosphatase 2, regulatory subunit A, beta a 
 dme-u.3   Pp2A-29B   Protein phosphatase 2A at 29B 
 cel-u.3   paa-1   putative serine/threonine-protein phosphatase PP2A regulatory subunit 
 mcc-u.3   PPP2R1B   protein phosphatase 2 scaffold subunit Abeta 
 mcc-u.3   PPP2R1A   protein phosphatase 2 scaffold subunit Aalpha 
 cfa-u.3   PPP2R1B   protein phosphatase 2 scaffold subunit Abeta 
 cfa-u.3   PPP2R1A   protein phosphatase 2 scaffold subunit Aalpha 

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Top 50 coexpressed genes to TPD3 (sce-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 sce3050   Proteasome  9 36 6.28
 sce3013   Nucleocytoplasmic transport  3 65 -
 sce4138   Autophagy - yeast  3 90 -
 sce4141   Protein processing in endoplasmic reticulum  3 93 -
 sce1240   Biosynthesis of cofactors  2 131 -

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sce:TPD3 (protein phosphatase 2A structural subunit TPD3) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

sce-u.3
for
TPD3
sce-r.3
for
TPD3
sce-m.4
for
TPD3
hsa-u.4
for
PPP2R1B
hsa-u.4
for
PPP2R1A
mmu-u.4
for
Ppp2r1b
mmu-u.4
for
Ppp2r1a
rno-u.3
for
Ppp2r1b
rno-u.3
for
Ppp2r1a
dre-u.3
for
ppp2r1bb
dre-u.3
for
ppp2r1ba
dme-u.3
for
Pp2A-29B
cel-u.3
for
paa-1
mcc-u.3
for
PPP2R1B
mcc-u.3
for
PPP2R1A
cfa-u.3
for
PPP2R1B
cfa-u.3
for
PPP2R1A
1 GPB2 Gpb2p 851243 YAL056W 6.8 3.8














2 APL2 Apl2p 853723 YKL135C 6.7 3.3
 3.1
 1.4
1.3
 4.9
3.7
 2.1
0.9
 4.9
4.5
 2.0
0.9
 5.4
2.6
 4.1
0.7
 5.5
0.7
 5.9
 6.3
 1.8
 4.7
2.2
 3.8
1.7
 4.7
3.1
3 PSK1 serine/threonine protein kinase PSK1 851216 YAL017W 5.9 3.3
1.0
 0.7
 0.2
 -0.3
 1.4
 -1.5
 -1.3
 -0.3
 -0.7
0.7
 1.0
 -1.7
 0.2
4 RPN3 proteasome regulatory particle lid subunit RPN3 856742 YER021W 5.9 3.2
 2.5
 2.0
 5.8
 0.6
 5.8
 0.5
 4.7
 4.9
 3.4
 3.3
 4.7
 1.1
 6.0
 2.0
 2.6
5 DOA1 Doa1p 853667 YKL213C 5.5 1.9
 3.3
 2.7
 1.8
 1.1
 1.4
 -0.3
 1.3
 4.1
 2.0
 2.4
 1.2
 1.3
 1.1
 -0.3
 1.4
6 PPH21 phosphoprotein phosphatase 2A catalytic subunit PPH21 851421 YDL134C 5.1 2.4
 2.5
 1.2
0.9
 5.1
2.9
 1.9
1.7
 4.3
2.3
 0.9
0.7
 3.4
3.0
 3.0
2.6
 4.3
3.4
 5.7
5.3
 8.3
2.9
 0.8
0.4
 2.9
2.4
 1.9
1.8
 4.0
2.4
7 AIP1 Aip1p 855117 YMR092C 5.1 3.0
 1.9
 0.8
 4.9
 2.9
 3.9
 1.1
 3.5
 3.1
 2.9
 1.7
 3.2
1.7
 0.6
 5.3
 2.6
 4.0
8 BCH1 exomer complex subunit 855277 YMR237W 5.0 2.7
 2.1













9 RPT3 proteasome regulatory particle base subunit RPT3 852003 YDR394W 5.0 2.6
 2.2
 1.6
 6.5
 1.3
 4.4
 1.3
 2.6
 6.3
 4.4
 3.3
0.1
 5.5
 1.7
 6.4
 1.5
 2.1
10 RPN6 proteasome regulatory particle lid subunit RPN6 851461 YDL097C 4.9 2.5
 2.2
 4.5
 3.9
 3.3
 2.9
 1.4
 2.7
 3.9
2.6
 2.3
1.6
 4.1
 7.8
 2.4
 2.3
 2.6
 0.9
11 QNS1 glutamine-dependent NAD(+) synthetase 856473 YHR074W 4.7 2.4
 2.2
 1.2
 0.3
 0.9
 -0.4
 1.4
 0.5
 0.6
 0.1
 0.9
 -0.2
 1.7
 0.0
 -0.5
 2.0
12 HFD1 hexadecenal dehydrogenase 855137 YMR110C 4.7 2.1
 2.5
 1.8
-0.1
 0.5
0.3
 1.4
0.7
 0.2
0.2
 0.7
0.2
 0.8
0.1
 1.5
1.0
 0.5
0.2
 2.2
 1.3
0.3
 0.3
0.1
 1.4
1.0
 -0.0
-0.7
 0.2
0.2
13 AIM2 protein AIM2 851248 YAL049C 4.7 3.4
 1.2
 -1.0
 -0.5
 -0.2
 -0.5
 0.5
 -1.1
 -1.8
 -1.0

0.3
 0.4
 -0.4
 -2.1
14 SAC6 fimbrin 851707 YDR129C 4.5 2.3
 2.0
 2.1
1.2
 1.2
0.9
 0.7
0.7
 2.7
1.3
 2.6
0.9
 2.1
-0.0
 0.7
-0.2
 -0.2
-0.6
 1.2
 1.8
 1.5
-0.0
 0.7
0.2
 1.1
1.0
 1.2
-0.2
15 PTC3 type 2C protein phosphatase PTC3 852224 YBL056W 4.4 2.5
1.2
0.1
 0.1
-0.7
 2.6
0.3
 0.3
-0.3
 0.2
-1.7
 -0.1
-0.6
 1.5
0.9
 3.2
0.7
 3.2
3.0
 1.2
0.4
 1.6
-1.1
 0.4
-0.4
 2.4
0.4
 1.6
0.8
16 YBP1 Ybp1p 852517 YBR216C 4.3 2.4
 1.8













17 SEC21 coatomer subunit gamma 855429 YNL287W 4.3 1.9
 2.2
 0.7
0.0
 2.9
2.0
 1.8
1.5
 3.1
2.8
 0.5
-0.1
 3.8
1.7
 3.6
 3.7
 2.1
 3.3
 1.2
0.6
 6.3
2.4
 0.3
-1.1
 2.3
0.6
18 RPN5 proteasome regulatory particle lid subunit RPN5 851408 YDL147W 4.2 1.8
 2.3
 2.2
 1.1
 1.5
 1.7
 1.2
 0.7
 4.0
 2.8
 2.4
 2.5
 2.4
 -0.9
 0.3
 0.1
19 RPN9 proteasome regulatory particle lid subunit RPN9 852037 YDR427W 4.2 1.8
 2.3
 1.6
 3.7
 1.5
 3.1
 1.5
 2.5
 2.2
 1.8
 2.1
 5.5
 1.8
 3.7
 1.4
 2.7
20 PBN1 Pbn1p 850305 YCL052C 4.2 2.2
 1.9













21 UBP6 ubiquitin-specific protease UBP6 850562 YFR010W 4.1 2.1
 1.9
 2.3
 1.4
 2.0
 3.5
 1.0
 3.6
 4.3
 3.7
 2.0
 5.8
 1.0
 1.1
 0.6
 1.6
22 HSM3 Hsm3p 852575 YBR272C 4.1 2.3
 1.7













23 STE11 mitogen-activated protein kinase kinase kinase STE11 851076 YLR362W 4.1 2.0
 2.0
 -0.8
-1.6
 -0.5
-0.5
 -1.0
-1.3
 -0.5
-1.5
 -0.6
-0.7
 0.4
-0.2
 -0.2
-0.6
 -0.6
-1.6

0.3
-1.0
 0.6
-1.0
 0.9
-0.8
 0.4
-0.2
24 CUB1 Cub1p 855867 YPL260W 4.1 2.3
 1.7













25 CDC48 AAA family ATPase CDC48 851431 YDL126C 4.0 1.5
 2.4
 2.9
1.7
 6.1
-0.3
 2.0
2.0
 5.0
-0.7
 1.0
0.2
 5.3
0.9
 5.2
1.2
 4.1
0.6
 6.1
-1.3
 6.7
6.1
 1.0
0.5
 6.0
-1.1
 1.3
0.8
 3.1
0.8
26 SRP1 karyopherin alpha 855532 YNL189W 4.0 2.2
 1.7
 1.8
1.4
 3.3
1.6
 1.9
1.7
 1.7
-0.2
 1.4
0.9
 0.6
0.2
 4.8
3.0
 5.4
5.3
 1.1
 1.6
 1.5
0.8
 3.1
0.9
 1.6
0.5
 1.1
1.0
27 RPT5 proteasome regulatory particle base subunit RPT5 854284 YOR117W 3.9 2.2
 1.6
 2.2
 3.7
 0.5
 3.3
 1.1
 1.9
 5.6
 5.2
 2.9
 5.6
 2.4
 2.0
 1.2
 2.9
28 ARP3 actin-related protein 3 853528 YJR065C 3.9 2.5
 1.4
 1.0
0.6
 3.0
0.3
 0.1
-0.5
 3.5
1.1
 0.7
-1.4
 4.1
1.4
 2.8
-0.4
 2.6
0.3
 4.5
 5.4
 0.6
-0.4
 1.1
-0.9
 2.1
-0.6
 1.4
-0.4
29 RPN1 proteasome regulatory particle base subunit RPN1 856422 YHR027C 3.9 2.0
 1.8
 2.8
 5.2
 3.5
 5.8
 2.3
 3.4
 4.9
 3.7
 3.7
 9.1
 2.0
 3.7
 2.7
 2.6
30 MON2 Mon2p 855420 YNL297C 3.9 2.1
 1.7
 0.6
 -1.0
 -0.0
 -0.5
 -0.3
 -1.1
 2.5
 2.5
 1.9
 2.1
 1.7
 -0.6
 0.0
 -0.7
31 RPN12 proteasome regulatory particle lid subunit RPN12 850613 YFR052W 3.9 2.0
 1.8
 0.4
 5.8
 -0.9
 2.3
 1.5
 2.2
 5.3
 3.1
 4.0
-0.9
 3.5
 1.0
 2.8
 1.5
 3.4
32 UFD2 ubiquitin-ubiquitin ligase UFD2 851337 YDL190C 3.8 2.2
2.0
 2.0
 0.2
 2.5
 0.1
 2.7
 3.7
 2.6
 2.2
 1.5
 2.1
 1.7
 3.0
 2.6
33 ENT3 Ent3p 853589 YJR125C 3.8 2.2
 1.5
 0.6
 -0.1
 1.6
 0.9
 -0.1
 1.2
 2.1
-0.7
 1.9
1.6
 0.5
 2.0
 1.7
 0.3
 2.1
 0.5
34 VPS1 dynamin-like GTPase VPS1 853870 YKR001C 3.8 1.7
 2.0
 1.8
 3.0
 0.0
 2.2
 -0.7
 2.3
 2.4
0.9
 1.4
1.2
 3.4
 3.5
 2.7
 1.7

35 ATG21 Atg21p 856004 YPL100W 3.8 1.9
 1.8













36 YPK1 serine/threonine protein kinase YPK1 853733 YKL126W 3.8 1.7
 2.0
 0.7
0.7
 -0.1
-0.6
 1.2
0.6
 0.2
-0.2
 2.2
1.8
 0.3
-0.5
 1.2
0.9
 0.9
0.2
-0.7
 1.5
0.7
 -0.5
-0.6
 3.7
1.5
 1.5
-0.3
37 CCT7 chaperonin-containing T-complex subunit CCT7 853333 YJL111W 3.8 1.6
 2.1
 1.5
 6.0
 1.8
 4.1
 1.5
 3.5
 3.2
 3.2
 1.1
 5.7
 2.5
 2.4
 0.4
0.3
 3.5
0.3
38 SLM1 phosphatidylinositol 4,5-bisphosphate-binding protein 854701 YIL105C 3.8 1.8
 1.9













39 NUP84 Nup84p 851441 YDL116W 3.7 1.7
 1.9
 2.2
 -0.1
 2.1
 1.3
 0.2
 -0.5
 3.1
 3.4
 1.4
2.2
 -0.0
 1.0
 -0.1
40 SIF2 Sif2p 852399 YBR103W 3.7 1.9
 1.8
 -0.4
-1.2
 0.1
-0.2
 1.3
0.5
 1.9
0.2
 0.0
 0.5
 0.7
-0.4
 0.2
-0.1
 3.8
1.3
0.1
 1.5
-0.7
 0.5
-0.9
 1.5
-0.6
41 UBA1 E1 ubiquitin-activating protein UBA1 853670 YKL210W 3.7 1.8
 1.8
 2.9
1.7
 7.5
1.5
 2.6
2.0
 9.0
0.6
 0.3
0.2
 7.1
0.0
 4.1
1.3
 4.1
0.7
 4.2
 5.0
 -0.7
-1.2
 7.0
-0.1
 3.2
1.1
 4.7
-0.1
42 RPT4 proteasome regulatory particle base subunit RPT4 854433 YOR259C 3.7 1.7
 1.9
 1.3
 1.0
 0.2
 1.5
 -0.4
 2.0
 5.8
 3.4
 5.0
0.6
 3.7
 1.2
 -0.3
 0.4
 -0.4
43 MSN5 karyopherin MSN5 851935 YDR335W 3.7 1.9
 1.7
 1.9
 1.3
 2.4
 2.5
 0.8
 2.1
 0.2
 0.7
 0.6
3.5
 3.2
 1.2
 1.2
44 MDR1 GTPase-activating protein MDR1 852992 YGR100W 3.7 1.9
 1.7
 -0.1
-0.3
 2.1
0.4
 0.4
-0.3
 1.2
0.2
 0.5
-0.0
 2.3
0.7
 0.3
0.2
 1.0
1.0
 1.5
 1.1
 0.5
0.4
 2.7
0.2
 0.6
0.3
 1.4
0.5
45 CDC24 Rho family guanine nucleotide exchange factor CDC24 851190 YAL041W 3.7 2.5
 1.1
 -1.0
 1.6
 0.1
-1.2
 1.0
0.9
 0.5
-0.3
 1.4
0.7
 2.0
-0.1
 0.9
-0.6
 1.0
1.1
-1.5
 1.2
0.7
 0.5
-0.4
 1.5
-1.3
46 SSL1 TFIIH/NER complex subunit SSL1 850691 YLR005W 3.6 1.5
 2.0
 1.4
 -1.4
 0.6
 -0.7
 0.8
 -0.7
 2.0
 1.7
 0.2
 0.8
 1.8
 -1.7
 0.6
 -2.4
47 CLF1 Clf1p 850808 YLR117C 3.6 1.9
 1.6
 0.5
 0.6
 1.9
 0.5
 -0.5
 0.9
 1.0
 0.8
 2.4
 3.4
 -0.2
 -0.0
 -0.1
 -0.3
48 MDM10 Mdm10p 851223 YAL010C 3.6 2.1














49 SHE4 She4p 854200 YOR035C 3.6 1.8
 1.7
 0.8
-0.9
 3.7
-0.4
 2.3
-0.4
 2.9
-0.6
 0.6
-0.3
 1.0
0.0
 1.6
0.5
 1.5
0.1
 0.3
 1.3
 -0.5
-0.6
 2.9
-0.8
 0.8
-0.7
 3.7
1.2
50 YAP1 DNA-binding transcription factor YAP1 855005 YML007W 3.6 1.3
 2.2













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