Orthologous genes in OrthoFinder**

Species Gene Description
 sce-u.3   TUS1   Rho family guanine nucleotide exchange factor TUS1 
 sce-r.3   TUS1   Rho family guanine nucleotide exchange factor TUS1 
 sce-m.4   TUS1   Rho family guanine nucleotide exchange factor TUS1 
 spo-u.3   nut2   mediator complex subunit Med10 
 hsa-u.4   ARHGEF12   Rho guanine nucleotide exchange factor 12 
 mmu-u.4   Arhgef12   Rho guanine nucleotide exchange factor (GEF) 12 
 rno-u.3   Arhgef12   Rho guanine nucleotide exchange factor 12 
 gga-u.3   ARHGEF12   Rho guanine nucleotide exchange factor 12 
 dre-u.3   arhgef12b   Rho guanine nucleotide exchange factor (GEF) 12b 
 dre-u.3   arhgef12a   Rho guanine nucleotide exchange factor (GEF) 12a 
 cel-u.3   rhgf-1   RHo Guanine nucleotide exchange Factor 
 mcc-u.3   ARHGEF12   Rho guanine nucleotide exchange factor 12 
 cfa-u.3   ARHGEF12   Rho guanine nucleotide exchange factor 12 

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Top 50 coexpressed genes to TUS1 (sce-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 sce4113   Meiosis - yeast  6 128 3.10
 sce4138   Autophagy - yeast  5 90 2.98
 sce4213   Longevity regulating pathway - multiple species  4 38 3.51
 sce4139   Mitophagy - yeast  3 40 2.31
 sce4011   MAPK signaling pathway - yeast  4 114 -

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sce:TUS1 (Rho family guanine nucleotide exchange factor TUS1) External Links;


Show/Hide Columns:        
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

sce-u.3
for
TUS1
sce-r.3
for
TUS1
sce-m.4
for
TUS1
spo-u.3
for
nut2
hsa-u.4
for
ARHGEF12
mmu-u.4
for
Arhgef12
rno-u.3
for
Arhgef12
gga-u.3
for
ARHGEF12
dre-u.3
for
arhgef12b
dre-u.3
for
arhgef12a
cel-u.3
for
rhgf-1
mcc-u.3
for
ARHGEF12
cfa-u.3
for
ARHGEF12
1 ROM2 Rho family guanine nucleotide exchange factor ROM2 851086 YLR371W 8.2 4.2
 3.7
0.4
0.3
 0.5
0.4
 1.5
0.5
 2.2
0.7
 1.6
-0.2
 1.5
0.3
1.7
-0.6
 0.4
-1.1
2 SSK2 mitogen-activated protein kinase kinase kinase SSK2 855765 YNR031C 7.5 3.6
 3.5
0.6
 1.1
 0.5
 1.4
 0.9
 4.7
0.1
 -0.2
3 DCK1 Dck1p 851141 YLR422W 5.8 2.5
 3.1
2.8
2.4
 3.6
1.7
 2.2
2.0
 2.0
1.4
 2.9
2.7
 1.0
0.6
 1.4
 2.6
1.8
 3.1
1.4
4 CSF1 Csf1p 850776 YLR087C 5.7 2.5
 3.0
2.8
 1.7
 1.2
 1.8
 1.1
 0.7
 1.8
 2.5
 0.6
5 SPO14 phospholipase D 853902 YKR031C 5.5 2.6
 2.7
 1.4
 0.8
-0.2
 1.6
1.1
 1.1
1.0
 1.3
 2.0
0.9
 3.2
1.7
 2.5
 0.1
-0.5
 1.4
0.6
6 UBP7 ubiquitin-specific protease UBP7 854650 YIL156W 5.5 3.3
 2.0









7 GPR1 Gpr1p 851527 YDL035C 5.4 2.5
 2.7
 0.3








8 TOR1 phosphatidylinositol kinase-related protein kinase TOR1 853529 YJR066W 5.4 3.5
 1.7
 -0.1
-1.4
 1.9
 2.7
 1.8
 1.7
 1.1
 0.9
 0.6
 2.1
 0.6
9 RAV1 Rav1p 853490 YJR033C 5.3 3.0
 2.1
2.0
0.2
 3.1
2.0
 3.0
0.9
 2.0
0.9
 0.5
-0.5
 1.4
1.2
 2.4
 0.3
-0.3
 2.1
1.0
10 SYT1 Arf family guanine nucleotide exchange factor SYT1 856210 YPR095C 5.1 3.0
 2.0
 2.8
 1.7
-0.3
 4.1
-0.5
 0.6
0.6
 1.7
0.5
 2.4
1.3
 2.6
2.5
 0.1
 0.2
0.2
 1.8
0.2
11 ATG26 sterol 3-beta-glucosyltransferase 850886 YLR189C 4.9 3.0
 1.8
0.6
0.3
 0.7
0.4
 0.7
0.4
 1.1
0.9
 1.7
1.5
 1.1
0.8
 1.6
1.4
 0.6
0.1
 0.0
-0.9
12 RAD26 DNA-dependent ATPase RAD26 853492 YJR035W 4.8 2.3
 2.4
0.9
 0.5
 1.8
 0.2
 0.2
 0.6
 0.6
0.1
 1.1
 0.9
13 SAC3 Sac3p 851737 YDR159W 4.8 2.0
 2.6
2.1
 0.4
 1.2
 1.2
 1.7
 3.1
 0.5
 0.4
 0.0
14 MDS3 Mds3p 852678 YGL197W 4.8 2.7
1.8








15 RIM15 protein kinase RIM15 850511 YFL033C 4.8 2.3
 2.4
-0.0
-0.7
 1.4
-1.1
 0.8
-0.4
 0.7
0.2
 1.2
1.2
 1.2
0.1
 1.3
0.7
 0.1
-0.2
 0.3
-0.5
16 BPH1 Bph1p 850398 YCR032W 4.8 2.7
 1.9
 1.4
0.5
 3.6
 5.0
-1.0
 4.8
0.1
 3.2
0.9
 2.7
 1.3
 1.3
 1.3
-1.0
 4.2
-0.2
17 PRP22 DEAH-box ATP-dependent RNA helicase PRP22 856732 YER013W 4.7 2.4
 2.1
1.7
0.8
 1.1
1.0
 0.9
0.8
 2.3
2.0
 2.8
1.1
 1.4
1.2
 1.1
0.9
 1.6
1.5
 0.4
0.2
18 MEC1 protein kinase MEC1 852433 YBR136W 4.5 2.0
 2.4
 2.2
 0.8
 0.4
 -0.7
 1.4
 2.4
 3.8
 0.8
 0.8
 1.7
19 TAO3 Tao3p 854677 YIL129C 4.5 2.7
 1.7
 0.5
-0.5
 2.4
1.0
 3.0
1.9
 4.5
1.7
 1.7
1.7
 2.2
1.9
 3.3
0.7
 2.3
 0.8
0.8
 0.9
-0.4
20 DNA2 bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease DNA2 856569 YHR164C 4.5 1.8
 2.6
0.7
 -0.5
-1.1
 0.6
 1.0
 -0.1
 2.4
 -0.7
21 SIN3 transcriptional regulator SIN3 854158 YOL004W 4.4 2.3
 2.0
 0.1
 0.1
-0.2
 -0.1
-1.4
 2.9
-0.0
 2.0
1.3
 -0.2
-0.2
 4.1
2.9
 1.0
 0.6
0.1
 1.2
-1.2
22 VPS13 membrane morphogenesis protein VPS13 850619 YLL040C 4.3 2.1
 2.1
 0.5
 3.0
2.1
 2.4
2.0
 0.6
 0.6
0.2
 0.4
-0.1
 1.7
1.1
 1.9
 2.7
2.0
 1.0
-0.0
23 PKH3 protein kinase PKH3 852077 YDR466W 4.3 2.0
 2.2









24 REV3 DNA-directed DNA polymerase 855936 YPL167C 4.3 1.6
 2.6
 -0.2
 1.6
 1.9
 1.4
 1.7
 0.8
 3.1
 0.4
 -0.3
 0.2
25 MIL1 Mil1p 850510 YFL034W 4.3 2.4
-0.3
 1.1
 0.4
 0.5
 0.6
 1.1
 1.3
 0.8
 0.4
 -0.9
26 ULS1 translocase ULS1 854363 YOR191W 4.2 2.4

0.8
 -0.6
 -0.3
0.6
 1.7
0.6
 0.1
27 MDR1 GTPase-activating protein MDR1 852992 YGR100W 4.2 2.0
 2.1
1.9
1.3
 0.9
0.6
 1.0
1.0
 3.4
0.8
 1.9
0.4
 3.4
1.0
 1.2
 1.2
0.7
 1.5
0.9
28 MIP1 DNA-directed DNA polymerase gamma MIP1 854508 YOR330C 4.2 2.4
-1.1
 -0.4
 0.3
 0.4
 -0.8
 -0.1
 0.9
 0.4
 -0.8
 0.4
29 VPS34 phosphatidylinositol 3-kinase VPS34 850941 YLR240W 4.2 2.0
 2.1
 0.5
 1.2
 0.3
 0.6
 0.3
 0.3
 2.8
 0.8
 -0.6
 -0.7
30 FAB1 1-phosphatidylinositol-3-phosphate 5-kinase 850574 YFR019W 4.2 2.4
0.5
 1.9
 1.9
 2.6
 0.5
 -0.1
 1.7
1.2
 0.7
31 SKI2 SKI complex RNA helicase subunit SKI2 851114 YLR398C 4.2 2.4
 1.6
0.5
0.4
 -0.5
-0.7
 1.7
-1.9
 1.2
-2.2
 1.0
-0.1
 2.5
1.1
 1.0
0.8
 0.2
-1.2
 0.3
-0.5
32 SIR3 chromatin-silencing protein SIR3 851163 YLR442C 4.2 2.4










33 FMP27 Fmp27p 851175 YLR454W 4.1 2.3
 1.7
2.8
 1.3
 2.5
 2.3

1.5
 2.8
 0.1
34 GCN2 serine/threonine-protein kinase GCN2 851877 YDR283C 4.1 2.0
 2.0
 0.4
 2.3
 1.4
 1.2
 0.1
 0.8
 2.6
 -0.8
 0.8
 0.4
35 MMS22 Mms22p 851030 YLR320W 4.1 2.5
 1.5









36 RGR1 Rgr1p 850760 YLR071C 4.1 2.1
 1.9
 -0.8
 0.4
 1.1
 -0.2
-0.8
 1.8
 -0.5
 2.6
 0.6
 0.4
 0.8
37 CDC15 serine/threonine protein kinase CDC15 851274 YAR019C 4.1 2.3


-0.2
 0.4
 -1.6
 0.4
 0.5


38 SEC3 GTP-Rho binding exocyst subunit SEC3 856726 YER008C 4.1 2.3
 1.7









39 VPS8 CORVET complex membrane-binding subunit VPS8 851261 YAL002W 4.0 2.6
 1.4
 0.6
0.1
 1.1
 1.8
 -0.5
 0.6
 1.3
 0.8
 -0.6
40 LAM1 Lam1p 856560 YHR155W 4.0 1.5
 2.4









41 SFI1 Sfi1p 850657 YLL003W 4.0 2.2
 1.7









42 ESL2 Esl2p 853971 YKR096W 4.0 2.3
 1.6









43 HER1 Her1p 854402 YOR227W 4.0 2.5
 1.5









44 PRP8 U4/U6-U5 snRNP complex subunit PRP8 856570 YHR165C 4.0 1.5
 2.3
 -0.4
 1.5
 2.6
 1.7
 3.2
 1.4
 1.0
 1.2
 -1.1
 1.0
45 CFT1 cleavage/polyadenylation factor CFT1 851895 YDR301W 4.0 1.7
 2.2
 -0.4
 -1.2
 0.2
 0.9
 -0.2
-0.9
 -0.6
 2.4
 0.1
 -0.8
 -0.7
46 BNI1 formin BNI1 855450 YNL271C 3.9 2.2

1.7
1.5
 1.4
-0.1
 0.5
-0.5
 1.8
1.8
 1.9
1.8
 1.5
-0.2
 1.0
-0.1
 1.6
-0.7
 0.3
-1.3
47 MHP1 Mhp1p 853408 YJL042W 3.9 2.3
 1.5









48 ALY1 Aly1p 853891 YKR021W 3.9 1.6
 2.2









49 CYR1 adenylate cyclase 853452 YJL005W 3.9 2.2
 1.6
3.6
1.0
 2.9
2.2
 2.8
2.4
 2.3
1.2
 -0.7
 1.2
 0.0
 2.5
-0.1
 3.2
0.9
50 SEA4 Sea4p 852170 YBL104C 3.9 1.5
 2.3
-0.5
 0.3
 -0.4
 0.1
 -0.9
 3.0
1.3
 0.8
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