Orthologous genes in OrthoFinder**

Species Gene Description
 mmu-u.4  Mmab  methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human) 
 mmu-r.6  Mmab  methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human) 
 mmu-m.5  Mmab  methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human) 
 rno-u.3  Mmab  metabolism of cobalamin associated B 
 hsa-u.4  MMAB  metabolism of cobalamin associated B 
 mcc-u.3  MMAB  metabolism of cobalamin associated B 
 cfa-u.3  MMAB  metabolism of cobalamin associated B 
 gga-u.3  MMAB  metabolism of cobalamin associated B 
 dre-u.3  mmab  metabolism of cobalamin associated B 
 cel-u.3  mmab-1  Corrinoid adenosyltransferase 

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Top 50 coexpressed genes to Mmab (mmu-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mmu100   Steroid biosynthesis  11 19 6.61
 mmu900   Terpenoid backbone biosynthesis  8 22 6.33
 mmu1212   Fatty acid metabolism  8 58 6.14
 mmu280   Valine, leucine and isoleucine degradation  5 51 6.42
 mmu1040   Biosynthesis of unsaturated fatty acids  4 31 5.71

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mmu:Mmab (methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)) External Links;


Show/Hide Columns:          
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID CoexPub LINK Target Reference

mmu-u.4
for
Mmab


mmu-r.6
for
Mmab


mmu-m.5
for
Mmab


rno-u.3
for
Mmab


hsa-u.4
for
MMAB


mcc-u.3
for
MMAB


cfa-u.3
for
MMAB


gga-u.3
for
MMAB


dre-u.3
for
mmab


cel-u.3
for
mmab-1

1 Mvk mevalonate kinase 17855 1 14.1 12.4
7.0
8.2
17.8
5.1
7.8
10.8
1.8
0.1
2 Nsdhl NAD(P) dependent steroid dehydrogenase-like 18194 0 10.3 10.9
4.1
4.2
10.8
3.8
3.4
6.1
1.5

3 Lss lanosterol synthase 16987 0 9.6 9.0
4.5
5.6
10.3
3.1
1.2
6.2
1.1

4 Mvd mevalonate (diphospho) decarboxylase 192156 0 9.4 9.6
4.0

12.2
3.6
2.6
4.8
1.2
1.7
5 Fdps farnesyl diphosphate synthetase 110196 0 9.3 8.8
4.3
4.4
13.2
1.3
2.3
7.4
1.8
3.0
6 Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 208715 0 9.2 9.6
3.8
5.2
-0.9
10.7
0.8
1.5
-0.2
2.0
0.4
3.2
-0.1
0.1
1.1
7 Fdft1 farnesyl diphosphate farnesyl transferase 1 14137 0 8.9 8.7
4.0
5.7
11.2
1.9
2.2
8.1
-0.5

8 Cyp51 cytochrome P450, family 51 13121 0 8.7 8.9
3.7
4.7
8.9
1.8
1.2

0.1

9 Acat2 acetyl-Coenzyme A acetyltransferase 2 110460 0 8.4 9.2
3.2
5.5
-0.6
12.8

3.3
3.7
1.3

10 Pmvk phosphomevalonate kinase 68603 0 8.2 8.6
3.4
4.0
3.7
3.3
1.2
4.6
1.1
-0.7
11 Dhcr7 7-dehydrocholesterol reductase 13360 0 8.1 8.8
3.2
4.2
3.6
12.0
6.8
2.8
2.8
2.5
1.6
4.3
1.1
0.2
-0.2
-0.0
12 Ldlr low density lipoprotein receptor 16835 0 8.0 7.4
3.9
4.8
-0.0
9.2
3.0
1.4
-0.8
2.2
1.5
4.8
1.5
1.7
-0.1
0.6
-1.6
13 Abcb8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 74610 0 8.0 6.5
4.3
4.2
2.1
2.6
0.9
1.8
1.4
1.3
14 Sc5d sterol-C5-desaturase 235293 0 7.9 7.8
3.5
3.6
7.7
0.4
1.9
4.0
2.1

15 Aacs acetoacetyl-CoA synthetase 78894 0 7.7 7.4
3.5
4.0
5.3
0.7
2.4
4.9
1.0
0.5
16 Msmo1 methylsterol monoxygenase 1 66234 0 7.7 7.4
3.5
5.1
10.6
2.3
1.2
0.5
5.5
0.8

17 Sqle squalene epoxidase 20775 0 7.6 7.6
3.3
4.0
9.0
1.3
0.4
5.2
-0.6

18 Insig1 insulin induced gene 1 231070 0 7.6 8.2
2.9
3.9
-1.0
9.6
-0.3
-0.0
-0.3
1.4
5.4
-0.5
0.8
-0.5

19 Idi1 isopentenyl-diphosphate delta isomerase 319554 0 7.5 7.1
3.5
3.5
10.3
2.4
-0.8
0.9
7.1
-1.7
0.6
20 Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 15490 0 7.4 6.7
3.7
6.9
9.9
1.8
2.3
5.3
1.9

21 Cyb5b cytochrome b5 type B 66427 0 7.3 7.1
3.3
3.8
-0.2
4.6
4.4
1.9
1.7
0.8
0.6
1.8
0.2
-0.8
-0.8
0.3
0.2
22 Tm7sf2 transmembrane 7 superfamily member 2 73166 0 6.9 8.0
2.4
4.2
3.6
12.0
6.8
2.8
2.8
2.5
1.6
4.3
1.1
0.2
-0.2
-0.0
23 Srebf2 sterol regulatory element binding factor 2 20788 0 6.5 6.5
2.8
4.7
3.4
8.6
5.2
1.1
0.9
1.6
5.5
2.4
-1.5
-1.8
-1.6
24 Stard4 StAR-related lipid transfer (START) domain containing 4 170459 0 6.4 6.4
2.8
3.9
0.3
1.0
1.8
1.1
1.6
0.7
5.2
2.8
0.1
0.0
1.0
25 Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase 15357 0 6.4 6.3
2.9
3.8
8.7
-0.0
1.5
4.9
0.8
0.1
1.8
26 Pcyt2 phosphate cytidylyltransferase 2, ethanolamine 68671 0 6.4 6.4
2.8
2.5
8.3
2.5
3.0
0.5
-1.2
2.5
-0.8
27 Dhcr24 24-dehydrocholesterol reductase 74754 0 6.1 6.1
2.7
5.4
10.3
2.7
1.9
4.7
2.0
-0.5
-1.5
28 Acly ATP citrate lyase 104112 0 6.1 6.0
2.8
4.5
4.8
0.5
2.2
2.4
0.7
0.6
0.5
0.5
29 Slc25a1 solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 13358 0 6.0 6.3
2.5
3.0
7.5
4.0
2.9
-0.1
0.0
-1.3
2.1
-0.6
30 Fasn fatty acid synthase 14104 0 5.8 6.7
2.1
4.3
8.4
1.0
2.7
2.0
-1.6
-0.1
31 Echdc1 enoyl Coenzyme A hydratase domain containing 1 52665 0 5.8 5.3
2.8
4.3
1.7
2.1
1.0
0.6

2.1
32 Mrps27 mitochondrial ribosomal protein S27 218506 0 5.7 5.6
2.6

2.1
1.4
2.3
-0.1
1.4
1.5
33 Tecr trans-2,3-enoyl-CoA reductase 106529 0 5.6 6.1
2.2
3.5
0.3
2.7
0.3
2.5
1.3
0.7
1.0
0.1
1.5
0.5
1.8
34 Acaca acetyl-Coenzyme A carboxylase alpha 107476 0 5.4 5.0
2.5
4.4
2.3
7.6
1.7
1.4
0.6
3.3
1.6
2.7
0.2
-0.8
-1.1
-0.4
35 Nudt2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 66401 0 5.3 5.4
2.3
1.8
2.0

2.3
0.7
0.9
4.0
36 Scd2 stearoyl-Coenzyme A desaturase 2 20250 0 5.3 5.1
2.4
3.3
3.0
10.5
0.5
1.8
0.3
0.8
0.3
2.9
1.0
0.6
0.5
0.6
-0.8
37 Acsl3 acyl-CoA synthetase long-chain family member 3 74205 0 5.2 5.3
2.2
1.9
1.1
4.5
1.6
0.5
-0.6
0.9
-0.6
2.7
-0.7
0.5
0.5
0.9
-1.3
38 Erg28 ergosterol biosynthesis 28 58520 0 5.1 4.7
2.5
2.8
10.0
3.0
3.9
4.4
0.4

39 Rdh11 retinol dehydrogenase 11 17252 0 5.1 5.3
2.1
0.5
0.2
4.9
1.2
2.2
1.5
1.6
1.4
3.5
1.0
2.7
1.8
3.4
2.4
40 Gpam glycerol-3-phosphate acyltransferase, mitochondrial 14732 0 5.1 4.6
2.5
2.8
1.4
0.9
0.5
0.0
-0.2
0.5
41 Mccc2 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) 78038 0 5.1 4.6
2.5
4.5
1.8
2.8
0.4
1.4
1.2
1.8
0.3
2.1
42 Fads2 fatty acid desaturase 2 56473 0 5.0 4.7
2.4
2.7
2.5
9.1
8.8
2.4
1.0
2.2
1.5
1.7
1.1
-0.3
1.3
0.2
43 Pcsk9 proprotein convertase subtilisin/kexin type 9 100102 0 5.0 4.6
2.4
4.3
4.2
0.4

0.4
-1.0

44 Gstz1 glutathione transferase zeta 1 (maleylacetoacetate isomerase) 14874 0 4.8 5.0
2.0
2.3
4.3
0.1
1.6
2.1
0.5
2.4
2.1
45 Fads1 fatty acid desaturase 1 76267 0 4.7 5.2
1.8
2.7
2.5
9.1
8.8
2.4
1.0
2.2
1.5
1.7
1.1
-0.3
1.3
0.2
46 D2hgdh D-2-hydroxyglutarate dehydrogenase 98314 0 4.7 4.7
2.1
1.9
1.5
2.6
0.9
0.4
2.5
2.3
47 Tbc1d7 TBC1 domain family, member 7 67046 0 4.7 4.1
2.4
3.9

0.9
2.9
0.7
-0.1

48 Gatb glutamyl-tRNA(Gln) amidotransferase, subunit B 229487 0 4.6 4.2
2.3
1.6
3.4
0.7
2.9
1.2
2.1
0.4
49 Kptn kaptin 70394 0 4.4 4.1
2.1
3.0
0.9
1.0
2.3
2.0
1.3

50 Ivd isovaleryl coenzyme A dehydrogenase 56357 0 4.3 4.9
1.6
2.0
2.6
2.6
1.2
0.7
0.3
1.0
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